HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC

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HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1000414
P3181OpenCitations bibliographic resource ID1596954
P932PMC publication ID2671846
P698PubMed publication ID19424423
P5875ResearchGate publication ID24410324

P50authorBarton HaynesQ4865631
Andrew James McMichaelQ21165187
Brian GaschenQ117221701
Elena E GiorgiQ122828494
Bette KorberQ30505218
Cathal SeoigheQ32937297
Beatrice H. HahnQ55293537
Tanmoy BhattacharyaQ55414889
Guido FerrariQ56481169
Brandon KeeleQ68690678
George M. ShawQ78514357
P2093author name stringMichael Liu
Marcus Daniels
Natasha Wood
P2860cites workConformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimeticQ22010407
The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and ImmunogensQ22242262
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HyPhy: hypothesis testing using phylogeniesQ29013475
Bayes empirical bayes inference of amino acid sites under positive selectionQ29547692
Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytesQ29616210
Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope geneQ29617599
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infectionQ29619510
Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptaseQ29619994
Population genetic estimation of the loss of genetic diversity during horizontal transmission of HIV-1.Q33237376
Vaccination and timing influence SIV immune escape viral dynamics in vivoQ33316821
Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantageQ33325923
Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertionsQ33732677
Rapid viral escape at an immunodominant simian-human immunodeficiency virus cytotoxic T-lymphocyte epitope exacts a dramatic fitness costQ33754974
Characterization of human immunodeficiency virus type 1 (HIV-1) envelope variation and neutralizing antibody responses during transmission of HIV-1 subtype B.Q33780595
Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levelsQ33780649
Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolutionQ34092644
Cellular immune responses to HIV.Q34223069
Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infectionQ34228730
Consistent patterns of change during the divergence of human immunodeficiency virus type 1 envelope from that of the inoculated virus in simian/human immunodeficiency virus-infected macaquesQ34301728
Human immunodeficiency virus type 1 env evolves toward ancestral states upon transmission to a new host.Q34353398
Accuracy and power of statistical methods for detecting adaptive evolution in protein coding sequences and for identifying positively selected sitesQ34569737
Effect of recombination on the accuracy of the likelihood method for detecting positive selection at amino acid sites.Q34617942
An HIV vaccine--evolving conceptsQ34629012
A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivoQ34858885
Targeting therapeutics to an exposed and conserved binding element of the HIV-1 fusion proteinQ34981730
Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivityQ35101464
Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolutionQ35634318
In vivo CD8+ T cell control of immunodeficiency virus infection in humans and macaquesQ35748658
Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infectionQ35857268
Mobile genetic elements: the agents of open source evolutionQ36247081
Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte responseQ36399559
Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencingQ36540055
Estimating selection pressures on HIV-1 using phylogenetic likelihood models.Q37081175
Models of coding sequence evolutionQ37089708
Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitopeQ37683431
Restraining the conformation of HIV-1 gp120 by removing a flexible loopQ38774625
Induction of multifunctional human immunodeficiency virus type 1 (HIV-1)-specific T cells capable of proliferation in healthy subjects by using a prime-boost regimen of DNA- and modified vaccinia virus Ankara-vectored vaccines expressing HIV-1 Gag cQ39028785
The C-terminal tail of the gp41 transmembrane envelope glycoprotein of HIV-1 clades A, B, C, and D may exist in two conformations: an analysis of sequence, structure, and functionQ40417980
HIV gp120: double lock strategy foils host defencesQ40843036
Co-evolution of human immunodeficiency virus and cytotoxic T-lymphocyte responses.Q41672909
In vivo fitness costs of different Gag CD8 T-cell escape mutant simian-human immunodeficiency viruses for macaquesQ42248380
Widespread adaptive evolution in the human immunodeficiency virus type 1 genomeQ45710774
HIV-1 subtype A envelope variants from early in infection have variable sensitivity to neutralization and to inhibitors of viral entryQ46170039
HIV evolution: CTL escape mutation and reversion after transmissionQ47211742
Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmissionQ47878972
Recco: recombination analysis using cost optimizationQ48024454
Automated phylogenetic detection of recombination using a genetic algorithm.Q51938478
Reversion of CTL escape–variant immunodeficiency viruses in vivoQ56427919
Founder Effects in the Assessment of HIV Polymorphisms and HLA Allele AssociationsQ56880587
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemiaQ57075698
Potential impact of recombination on sitewise approaches for detecting positive natural selectionQ59192521
HIV-1 Epitope-Specific CD8+ T Cell Responses Strongly Associated with Delayed Disease Progression Cross-Recognize Epitope Variants EfficientlyQ61053915
Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDSQ73034306
Simulation study of the reliability and robustness of the statistical methods for detecting positive selection at single amino acid sitesQ78461368
PCR-sequence-specific primer typing of HLA class I and class II allelesQ78464052
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectHIVQ15787
P304page(s)e1000414
P577publication date2009-05-01
P1433published inPLOS PathogensQ283209
P1476titleHIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC
P478volume5

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