Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

scientific article

Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2010PLoSO...512303F
P356DOI10.1371/JOURNAL.PONE.0012303
P932PMC publication ID2924888
P698PubMed publication ID20808830
P5875ResearchGate publication ID46108576

P50authorBarton HaynesQ4865631
Andrew James McMichaelQ21165187
Persephone BorrowQ28839540
Vitaly GanusovQ41045019
Will FischerQ54215194
Beatrice H. HahnQ55293537
Tanmoy BhattacharyaQ55414889
Alan S. PerelsonQ55719625
Chien-Chi LoQ56433234
Timothy C. WallstromQ56808373
Brandon KeeleQ68690678
George M. ShawQ78514357
Thomas LeitnerQ84143742
Elena E GiorgiQ122828494
Bette KorberQ30505218
Peter T. HraberQ37366689
P2093author name stringLance Green
Cliff S Han
Shuyi Wang
Ambarish Nag
Cheryl D Gleasner
P2860cites workHIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBECQ21559422
Mutations of Bacteria from Virus Sensitivity to Virus ResistanceQ24533278
Genome sequencing in microfabricated high-density picolitre reactorsQ24544260
Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infectionQ24645815
A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamicsQ24682089
Inefficient cytotoxic T lymphocyte-mediated killing of HIV-1-infected cells in vivoQ25255777
A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum LikelihoodQ27861000
Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virusQ28302762
APE: Analyses of Phylogenetics and Evolution in R languageQ29546513
Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine designQ41338220
Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeysQ43212235
Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infectionQ43542210
Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infectionQ45771143
A new perspective on V3 phenotype prediction.Q45967036
Higher set point plasma viral load and more-severe acute HIV type 1 (HIV-1) illness predict mortality among high-risk HIV-1-infected African womenQ46695815
Systematic artifacts in metagenomes from complex microbial communities.Q51655718
Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants.Q51926211
HIV-1 Epitope-Specific CD8+ T Cell Responses Strongly Associated with Delayed Disease Progression Cross-Recognize Epitope Variants EfficientlyQ61053915
HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation timeQ29547822
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infectionQ29619510
Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptaseQ29619994
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV InfectionQ33239376
Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1Q33290217
Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivoQ33455862
Accurate determination of microbial diversity from 454 pyrosequencing dataQ33492259
Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequencesQ33545560
High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men.Q33582135
Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeysQ33712291
Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeysQ33712578
Wide variation in the multiplicity of HIV-1 infection among injection drug usersQ33877419
Hepatitis C virus transmission bottlenecks analyzed by deep sequencing.Q33877425
Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte responseQ36399559
Fitness constraints on immune escape from HIV: Implications of envelope as a target for both HIV-specific T cells and antibodyQ36447143
Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequencesQ36637273
Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infectionQ36898637
Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variantsQ37145228
Transmission and long-term stability of compensated CD8 escape mutationsQ37145270
Rare HLA drive additional HIV evolution compared to more frequent allelesQ37219577
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infectionQ37273158
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infectionQ37273195
Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipientsQ37273283
Ultradeep pyrosequencing detects complex patterns of CD8+ T-lymphocyte escape in simian immunodeficiency virus-infected macaquesQ37275022
Modeling sequence evolution in acute HIV-1 infectionQ37384535
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectevasion of host immune responseQ1660157
HIV transmissionQ49029021
P304page(s)e12303
P577publication date2010-08-20
P1433published inPLOS OneQ564954
P1476titleTransmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing
P478volume5

Reverse relations

cites work (P2860)
Q34733504A mechanistic understanding of allosteric immune escape pathways in the HIV-1 envelope glycoprotein
Q34960846A multiple-alignment based primer design algorithm for genetically highly variable DNA targets
Q40047295A novel HIV vaccine targeting the protease cleavage sites
Q38853281A penalized regression approach to haplotype reconstruction of viral populations arising in early HIV/SIV infection
Q36167660A quantitative quasispecies theory-based model of virus escape mutation under immune selection
Q35647691Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID
Q34185814Acute HIV-1 Infection
Q34720403Acute phase CD8+ T lymphocytes against alternate reading frame epitopes select for rapid viral escape during SIV infection
Q52595348Analysis of HIV-1 envelope evolution suggests antibody-mediated selection of common epitopes among Chinese former plasma donors from a narrow-source outbreak.
Q36878885Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds
Q36267348Antigenic characterization of the human immunodeficiency virus (HIV-1) envelope glycoprotein precursor incorporated into nanodiscs
Q35600172Applications of next-generation sequencing technologies to diagnostic virology
Q92226023Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection
Q38839394Autologous Stem Cell Transplantation Disrupts Adaptive Immune Responses during Rebound Simian/Human Immunodeficiency Virus Viremia
Q37272098Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression.
Q38063560Biology as population dynamics: heuristics for transmission risk
Q28082862Bottlenecks in HIV-1 transmission: insights from the study of founder viruses
Q35823144Broad CTL Response in Early HIV Infection Drives Multiple Concurrent CTL Escapes
Q35592229Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection
Q33743734CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies
Q30397667CD8(+)T-cell-mediated control of HIV-1 and SIV infection
Q37308724Can non-lytic CD8+ T cells drive HIV-1 escape?
Q26781511Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV Reservoirs
Q28727944Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data
Q35895762Clonality and intracellular polyploidy in virus evolution and pathogenesis
Q35759184Comparison of Major and Minor Viral SNPs Identified through Single Template Sequencing and Pyrosequencing in Acute HIV-1 Infection
Q36172206Comparison of a high-resolution melting assay to next-generation sequencing for analysis of HIV diversity
Q36978861Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design
Q36079024Competitive exclusion by autologous antibodies can prevent broad HIV-1 antibodies from arising
Q30421085Complete viral RNA genome sequencing of ultra-low copy samples by sequence-independent amplification
Q36972240Computational inference methods for selective sweeps arising in acute HIV infection
Q36154322Conflicting selection pressures on T-cell epitopes in HIV-1 subtype B.
Q35826200Contribution of intra- and interhost dynamics to norovirus evolution
Q40409331Deep Sequencing of the Hepatitis B Virus Genome: Analysis of Multiple Samples by Implementation of the Illumina Platform
Q28546549Deep sequencing of protease inhibitor resistant HIV patient isolates reveals patterns of correlated mutations in Gag and protease
Q42118138Deep sequencing of virus-infected cells reveals HIV-encoded small RNAs
Q30410411Defining epitope coverage requirements for T cell-based HIV vaccines: theoretical considerations and practical applications
Q35140450Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants.
Q28551914Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus
Q36414547Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages
Q34308788Early immune adaptation in HIV-1 revealed by population-level approaches
Q36000736Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape
Q28822525Epigraph: A Vaccine Design Tool Applied to an HIV Therapeutic Vaccine and a Pan-Filovirus Vaccine
Q41368316Epitope-specific CD8+ T cell kinetics rather than viral variability determine the timing of immune escape in simian immunodeficiency virus infection
Q35076549Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection
Q38855080Epstein-Barr virus latent membrane protein 1 genetic variability in peripheral blood B cells and oropharyngeal fluids
Q37442895Escape from CD8(+) T cell responses in Mamu-B*00801(+) macaques differentiates progressors from elite controllers
Q90629776Estimating the Timing of Early Simian-Human Immunodeficiency Virus Infections: a Comparison between Poisson Fitter and BEAST
Q34227393Estimating the strength of selective sweeps from deep population diversity data.
Q31057988Estimation of genetic diversity in viral populations from next generation sequencing data with extremely deep coverage
Q34193198Evaluation of cervical mucosa in transmission bottleneck during acute HIV-1 infection using a cervical tissue-based organ culture
Q39938731Evolution of foot-and-mouth disease virus intra-sample sequence diversity during serial transmission in bovine hosts
Q38108358Evolutionary dynamics and information hierarchies in biological systems
Q56914147First-Class Control of HIV-1
Q35274776Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection
Q42239239Fitness valleys constrain HIV-1's adaptation to its secondary chemokine coreceptor.
Q35665770For protection from HIV-1 infection, more might not be better: a systematic analysis of HIV Gag epitopes of two alleles associated with different outcomes of HIV-1 infection
Q60957354Full-Length Envelope Analyzer (FLEA): A tool for longitudinal analysis of viral amplicons
Q35826158Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages
Q46236976Genetic analysis of a rabies virus host shift event reveals within-host viral dynamics in a new host
Q57196807Genetic diversity and molecular epidemiology of HIV transmission
Q42113280Grand Challenges in the Immunology of HIV and AIDS
Q40354550Graph-based optimization of epitope coverage for vaccine antigen design
Q47548221HIV evolution and diversity in ART-treated patients
Q37853935HIV sexual transmission and microbicides
Q36526615HIV transmission
Q40168307HIV-1 Epitope Variability Is Associated with T Cell Receptor Repertoire Instability and Breadth
Q34957142HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention
Q34864743HIV-1 envelope accessible surface and polarity: clade, blood, and brain
Q37913478HIV-1 evolution in relation to molecular epidemiology and antiretroviral resistance
Q38765830HIV-1 full-genome phylogenetics of generalized epidemics in sub-Saharan Africa: impact of missing nucleotide characters in next-generation sequences
Q28536682HIV-1 transmission during early infection in men who have sex with men: a phylodynamic analysis
Q82718989HIV-1: from escapism to conservatism
Q35188022High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection
Q47551736Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection.
Q39250937Homogenous HIV-1 subtype B quasispecies in Brazilian men and women recently infected via heterosexual transmission
Q40054979How germinal centers evolve broadly neutralizing antibodies: the breadth of the follicular helper T cell response.
Q33982561Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection
Q34332536Human cytomegalovirus intrahost evolution-a new avenue for understanding and controlling herpesvirus infections
Q27012467Human endogenous retroviruses and the nervous system
Q34407843Human immunodeficiency virus type-1 (HIV-1) continues to evolve in presence of broadly neutralizing antibodies more than ten years after infection
Q36702615Human immunodeficiency viruses appear compartmentalized to the female genital tract in cross-sectional analyses but genital lineages do not persist over time
Q35192955Human leukocyte antigen variants B*44 and B*57 are consistently favorable during two distinct phases of primary HIV-1 infection in sub-Saharan Africans with several viral subtypes
Q55299659Hybrid stochastic framework predicts efficacy of prophylaxis against HIV: An example with different dolutegravir prophylaxis schemes.
Q35798108Immune-mediated attenuation of HIV-1
Q51002244Immunogenicity of sequences around HIV-1 protease cleavage sites: potential targets and population coverage analysis for a HIV vaccine targeting protease cleavage sites.
Q42208915Impaired Nef function is associated with early control of HIV-1 viremia
Q51384061Impaired immune evasion in HIV through intracellular delays and multiple infection of cells.
Q28477088Implications of CTL-mediated killing of HIV-infected cells during the non-productive stage of infection
Q35009489Improved detection of rare HIV-1 variants using 454 pyrosequencing
Q35790802In-depth characterization of viral isolates from plasma and cells compared with plasma circulating quasispecies in early HIV-1 infection.
Q30658257Indel and Carryforward Correction (ICC): a new analysis approach for processing 454 pyrosequencing data
Q34985572Inferring HIV Escape Rates from Multi-Locus Genotype Data
Q40301168Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment
Q35993707Interplay between HIV-1 and Host Genetic Variation: A Snapshot into Its Impact on AIDS and Therapy Response.
Q90362089Into the Deep (Sequence) of the Foot-and-Mouth Disease Virus Gene Pool: Bottlenecks and Adaptation during Infection in Naïve and Vaccinated Cattle
Q35909939Investigating the Consequences of Interference between Multiple CD8+ T Cell Escape Mutations in Early HIV Infection
Q30414086Limited nucleotide changes in the Rev response element (RRE) during HIV-1 infection alter overall Rev-RRE activity and Rev multimerization
Q36246646Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants
Q92523449Longitudinal within-host evolution of HIV Nef-mediated CD4, HLA and SERINC5 downregulation activity: a case study
Q48165950Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults
Q37653075Mathematical modeling of escape of HIV from cytotoxic T lymphocyte responses.
Q64235564Mechanistic framework predicts drug-class specific utility of antiretrovirals for HIV prophylaxis
Q36887522Modeling sequence evolution in HIV-1 infection with recombination
Q21245370Modeling the within-host dynamics of HIV infection
Q39535964Modelling the spread of HIV immune escape mutants in a vaccinated population
Q33900353Molecularly tagged simian immunodeficiency virus SIVmac239 synthetic swarm for tracking independent infection events
Q38507640Mutations in a dominant Nef epitope of simian immunodeficiency virus diminish TCR:epitope peptide affinity but not epitope peptide:MHC class I binding
Q30652082Nautilus: a bioinformatics package for the analysis of HIV type 1 targeted deep sequencing data
Q56880081New insights into the evolutionary rate of HIV-1 at the within-host and epidemiological levels
Q38020606Next generation deep sequencing and vaccine design: today and tomorrow
Q35873113Next-Generation Sequencing Reveals Frequent Opportunities for Exposure to Hepatitis C Virus in Ghana
Q58755453Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control
Q34574693Observing micro-evolutionary processes of viral populations at multiple scales
Q47547864On the Demographic and Selective Forces Shaping Patterns of Human Cytomegalovirus Variation within Hosts
Q61454368On the unfounded enthusiasm for soft selective sweeps II: Examining recent evidence from humans, flies, and viruses
Q42680526Patterns and rates of viral evolution in HIV-1 subtype B infected females and males
Q90466201Personalized viral genomic investigation of herpes simplex virus 1 perinatal viremic transmission with dual fatality
Q34539700Phylodynamic inference and model assessment with approximate bayesian computation: influenza as a case study
Q30404569Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants
Q58762598Phylogenetic approach to recover integration dates of latent HIV sequences within-host
Q59355665Phylogenetic patterns recover known HIV epidemiological relationships and reveal common transmission of multiple variants
Q39108740Polyvalent vaccine approaches to combat HIV-1 diversity
Q36479690Population genomics of intrapatient HIV-1 evolution
Q38146008Population genomics of rapid adaptation by soft selective sweeps.
Q37272324Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells
Q35541130PrimerDesign-M: a multiple-alignment based multiple-primer design tool for walking across variable genomes
Q37273690Programmed death-1 is a marker for abnormal distribution of naive/memory T cell subsets in HIV-1 infection.
Q35034097Properties of MHC class I presented peptides that enhance immunogenicity
Q37252805Quantifying selection against synonymous mutations in HIV-1 env evolution.
Q37643964Quantitative characterization of defective virus emergence by deep sequencing
Q36154488Quantitative experimental determination of primer-dimer formation risk by free-solution conjugate electrophoresis
Q36936058Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice
Q38849453Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection
Q34269570Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection.
Q34042642Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections
Q33828583Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection
Q42208022Reliable reconstruction of HIV-1 whole genome haplotypes reveals clonal interference and genetic hitchhiking among immune escape variants.
Q38398452Restriction of V3 region sequence divergence in the HIV-1 envelope gene during antiretroviral treatment in a cohort of recent seroconverters
Q34303615Retroviral vectors for analysis of viral mutagenesis and recombination
Q33910862Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus
Q35558621Role of donor genital tract HIV-1 diversity in the transmission bottleneck
Q28742018SHIV-162P3 infection of rhesus macaques given maraviroc gel vaginally does not involve resistant viruses
Q27313564SIV genome-wide pyrosequencing provides a comprehensive and unbiased view of variation within and outside CD8 T lymphocyte epitopes
Q35581949SIVmac251 is inefficiently transmitted to rhesus macaques by penile inoculation with a single SIVenv variant found in ramp-up phase plasma
Q30407004Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection
Q42213317Short communication: HIV-1 gag genetic variation in a single acutely infected participant defined by high-resolution deep sequencing
Q42795407Simulation of B cell affinity maturation explains enhanced antibody cross-reactivity induced by the polyvalent malaria vaccine AMA1.
Q36433960Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification
Q34700534Soft selective sweeps in complex demographic scenarios.
Q36231944Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics
Q33815539Stochastic theory of early viral infection: continuous versus burst production of virions
Q35099081Structured observations reveal slow HIV-1 CTL escape
Q34451254Targeted deep sequencing of HIV-1 using the IonTorrentPGM platform
Q36093618Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection
Q34936638The Effect of Interference on the CD8(+) T Cell Escape Rates in HIV.
Q36856091The HIV-1 env protein: a coat of many colors
Q34642996The T-cell response to HIV.
Q42593675The dynamics of HIV-1 adaptation in early infection.
Q37949561The emerging role of leukocyte immunoglobulin-like receptors (LILRs) in HIV-1 infection
Q35671910The evolution of HIV: inferences using phylogenetics
Q35377813The route of HIV escape from immune response targeting multiple sites is determined by the cost-benefit tradeoff of escape mutations
Q54263974Time Intervals in Sequence Sampling, Not Data Modifications, Have a Major Impact on Estimates of HIV Escape Rates.
Q33618602Transcytosis of HIV-1 through vaginal epithelial cells is dependent on trafficking to the endocytic recycling pathway
Q40634933Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection
Q34583054Ultra-deep mutant spectrum profiling: improving sequencing accuracy using overlapping read pairs
Q30240629Understanding the complex evolution of rapidly mutating viruses with deep sequencing: Beyond the analysis of viral diversity
Q42234045Untangling the influences of unmodeled evolutionary processes on phylogenetic signal in a forensically important HIV-1 transmission cluster
Q26861425Using nonhuman primates to model HIV transmission
Q36497283Vertical T cell immunodominance and epitope entropy determine HIV-1 escape
Q27349889Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques
Q35593158Viral determinants of HIV-1 macrophage tropism
Q33844706Viral linkage in HIV-1 seroconverters and their partners in an HIV-1 prevention clinical trial
Q36179597Viral population dynamics and virulence thresholds
Q27013917Viral quasispecies evolution
Q41929341Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.
Q39400038Virus-Host Gene Interactions Define HIV-1 Disease Progression.
Q47593460Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico
Q30469621Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection
Q33619649Within-Epitope Interactions Can Bias CTL Escape Estimation in Early HIV Infection

Search more.