The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid

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The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...732964W
P356DOI10.1371/JOURNAL.PONE.0032964
P932PMC publication ID3314661
P698PubMed publication ID22470433
P5875ResearchGate publication ID223983021

P50authorNicolas ChomontQ56909197
Jean-Pierre RoutyQ86903586
Cécile TremblayQ88627432
Vanessa Sue WaclecheQ92703971
Petronela AncutaQ120389399
P2093author name stringMathieu Goupil
Annie Gosselin
Hassen Kared
Mohamed-Rachid Boulassel
Nicole Bernard
Patricia Monteiro
P2860cites workEmerging concepts in the immunopathogenesis of AIDSQ22241984
CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tractQ22242965
Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tractQ22242981
Microbial translocation is a cause of systemic immune activation in chronic HIV infectionQ22251054
HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cellsQ22251066
The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammatQ24648890
Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cellsQ28201575
The major genetic determinants of HIV-1 control affect HLA class I peptide presentationQ29417018
Development, cytokine profile and function of human interleukin 17-producing helper T cellsQ29617131
Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infectionQ29619124
Retinoic acid imprints gut-homing specificity on T cellsQ29619126
Phenotypic and functional features of human Th17 cellsQ29619323
Lymphocyte homing and homeostasisQ29619924
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cellsQ29622847
Targeting early infection to prevent HIV-1 mucosal transmission.Q30386549
Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7.Q50638760
Early proliferation of CCR5(+) CD38(+++) antigen-specific CD4(+) Th1 effector cells during primary HIV-1 infection.Q51991924
Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.Q51993308
Changes in immunological and virological parameters in HIV-1 infected subjects following leukapheresis.Q52006628
A live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profilesQ62577375
Quantification of physiological levels of retinoic acidQ69497333
Wall shear stress: the missing step for T cell transmigration?Q73933996
Trapping and apoptosis of novel subsets of memory T lymphocytes expressing CCR6 in the spleen of HIV-infected patientsQ79466226
Immune reconstitution in the sigmoid colon after long-term HIV therapyQ82949871
HLA/KIR restraint of HIV: surviving the fittestQ37051248
Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune controlQ37054526
Retinoic acid-dependent regulation of immune responses by dendritic cells and macrophagesQ37096952
The gastrointestinal tract and AIDS pathogenesisQ37128853
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infectionQ37273158
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infectionQ37273195
T-cell recruitment to the intestinal mucosaQ37288118
Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infectionQ37366149
Migration, maintenance and recall of memory T cells in peripheral tissuesQ37400599
Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity.Q37401744
The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.Q37428017
Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1.Q37446484
HIV: a discovery opening the road to novel scientific knowledge and global health improvementQ37691603
Th17 lineage commitment and HIV-1 pathogenesisQ37764652
HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individualsQ37771138
Maintenance of CD4+ T-cell memory and HIV persistence: keeping memory, keeping HIV.Q37829627
Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection.Q38984682
Virus-specific interleukin-17-producing CD4+ T cells are detectable in early human immunodeficiency virus type 1 infectionQ39766907
Resistance of chemokine receptor 6-deficient mice to Yersinia enterocolitica infection: evidence of defective M-cell formation in vivoQ41445006
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.Q41541656
HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesisQ41952863
The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut.Q43095069
HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi.Q44368205
Long-term nonprogressive disease among untreated HIV-infected individuals: clinical implications of understanding immune control of HIV.Q44910750
Human immunodeficiency virus type 1 infection is associated with significant mucosal inflammation characterized by increased expression of CCR5, CXCR4, and beta-chemokinesQ44965151
Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responsesQ46137651
Early events in sexual transmission of HIV and SIV and opportunities for interventionsQ30395919
Gut-associated lymphoid tissue-primed CD4+ T cells display CCR9-dependent and -independent homing to the small intestine.Q33230787
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patientsQ33346244
Autocrine production of beta-chemokines protects CMV-Specific CD4 T cells from HIV infectionQ33513965
Dynamic T cell migration program provides resident memory within intestinal epitheliumQ33730150
Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressorsQ33865979
HIV preferentially infects HIV-specific CD4+ T cellsQ33958893
Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut.Q33984007
Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissueQ34152017
Retinoic acid: an educational "vitamin elixir" for gut-seeking T cellsQ34358924
Natural suppression of human immunodeficiency virus type 1 replication is mediated by transitional memory CD8+ T cells.Q34529732
Infection of CD127+ (interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infectionQ34571341
HIV infection and the gastrointestinal immune systemQ34601874
HIV-specific CD4+ T cells may contribute to viral persistence in HIV controllersQ34699130
Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infectionQ34976860
Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infectionQ35064033
Chemokines in lymphocyte trafficking and intestinal immunityQ35173622
Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte traffickingQ35208814
The search for the CD8+ cell anti-HIV factor (CAF).Q35595818
Chemoattractants and their receptors in homeostasis and inflammationQ35931538
Decreased CXCR3+ CD8 T cells in advanced human immunodeficiency virus infection suggest that a homing defect contributes to cytotoxic T-lymphocyte dysfunctionQ35947828
Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapyQ36304297
CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skinQ36370073
HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacityQ36371562
HIV disease: fallout from a mucosal catastrophe?Q36398125
Getting to the guts of HIV pathogenesisQ36399719
CCR6 and CCL20: partners in intestinal immunity and lymphorganogenesisQ36631416
Current concepts in AIDS pathogenesis: insights from the SIV/macaque modelQ36705227
Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infectionsQ36915902
Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapyQ36950611
HIV controllers: how do they tame the virus?Q36991310
Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapyQ37033224
The highway code of T cell trafficking.Q37045760
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecttretinoinQ29417
P304page(s)e32964
P577publication date2012-03-28
P1433published inPLOS OneQ564954
P1476titleThe colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid
P478volume7

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cites work (P2860)
Q40800676A high rate of β7+ gut homing lymphocytes in HIV infected Immunogical Non Responders is associated with poor CD4 T cell recovery during suppressive HAART.
Q40699445Brief Report: A High Rate of β7+ Gut-Homing Lymphocytes in HIV-Infected Immunological Nonresponders is Associated With Poor CD4 T-Cell Recovery During Suppressive HAART
Q58076945CD16 monocytes give rise to CD103RALDH2TCF4 dendritic cells with unique transcriptional and immunological features
Q38631641Characterization of Mycobacterium tuberculosis-Specific Cells Using MHC Class II Tetramers Reveals Phenotypic Differences Related to HIV Infection and Tuberculosis Disease
Q21090481Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration
Q40114928Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.
Q26748743Gut barrier structure, mucosal immunity and intestinal microbiota in the pathogenesis and treatment of HIV infection
Q36364264Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach
Q34351320Immune activation and HIV persistence: implications for curative approaches to HIV infection
Q40625213Mucosal Regulatory T Cells and T Helper 17 Cells in HIV-Associated Immune Activation
Q40565584New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy
Q37587740Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

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