Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM.

scientific article

Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/EMBOJ/19.5.882
P932PMC publication ID305628
P698PubMed publication ID10698930
P5875ResearchGate publication ID232763522

P50authorHidde PloeghQ1617296
P2093author name stringG P Shi
H A Chapman
J A Villadangos
C Driessen
P2860cites workThe structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3Q24303524
Exploring the mechanisms of antigen processing by cell fractionationQ58199442
On the complexity of selfQ59092662
Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartmentsQ71843540
Allelic differences affecting invariant chain dependency of MHC class II subunit assemblyQ72112282
Selective modulation of the major histocompatibility complex class II antigen presentation pathway following B cell receptor ligation and protein kinase C activationQ73025366
Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null miceQ74595052
Large protein fragments as substrates for endocytic antigen capture by MHC class II moleculesQ77436913
Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loadingQ24328923
HLA-DM - an endosomal and lysosomal chaperone for the immune systemQ28143818
H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selectionQ28504958
Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathwayQ28507891
Antigen presentation and T cell development in H2-M-deficient miceQ28587240
Cathepsin S required for normal MHC class II peptide loading and germinal center developmentQ28611850
Self-release of CLIP in peptide loading of HLA-DR moleculesQ28612830
Negative Regulation by HLA-DO of MHC Class II-Restricted Antigen ProcessingQ28613199
Cathepsin L: Critical Role in Ii Degradation and CD4 T Cell Selection in the ThymusQ28613227
Assembly, transport, and function of MHC class II moleculesQ34328789
Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulumQ35843755
Defective intracellular transport as a common mechanism limiting expression of inappropriately paired class II major histocompatibility complex alpha/beta chainsQ36230461
Ii chain controls the transport of major histocompatibility complex class II molecules to and from lysosomes.Q36274077
Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells.Q36301521
The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodiesQ36351071
Specificity and promiscuity among naturally processed peptides bound to HLA-DR allelesQ36361966
The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancyQ36363714
The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent.Q36364225
Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesiclesQ36364770
Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CLQ36367626
HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR moleculesQ36377428
Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex PolymorphismQ36380525
Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentationQ36475793
Difference in antigen presentation pathways between cortical and medullary thymic epithelial cellsQ36820591
Cathepsin S activity regulates antigen presentation and immunityQ37382422
How MHC class II molecules reach the endocytic pathwayQ37693338
Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.Q40792165
How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathwayQ41020969
A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules.Q41030957
HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loadingQ41064461
Distinct antigen MHC class II complexes generated by separate processing pathways.Q41079003
Association between HLA-DM and HLA-DR in vivoQ41254547
Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump.Q41317185
In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptidesQ41418920
MHC class II function preserved by low-affinity peptide interactions preceding stable bindingQ41447819
Capture and processing of exogenous antigens for presentation on MHC molecules.Q41464375
Vacuolar ATPase activity is required for endosomal carrier vesicle formationQ41495121
Involvement of the vacuolar H(+)-ATPases in the secretory pathway of HepG2 cells.Q41528376
Endosomal proteolysis and MHC class II functionQ41729834
Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells.Q47872621
The role of endosomes and lysosomes in MHC class II functioningQ47927773
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)882-891
P577publication date2000-03-01
P1433published inThe EMBO JournalQ1278554
P1476titleEarly endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM.
P478volume19

Reverse relations

cites work (P2860)
Q38358249Activity and subcellular distribution of cathepsins in primary human monocytes
Q34129315Antigen processing in the endocytic compartment
Q93020630Class II MHC antigen processing in immune tolerance and inflammation
Q36266484Control of MHC class II antigen presentation in dendritic cells: a balance between creative and destructive forces.
Q46509529DM, but not cathepsin L, is required to control an aerosol infection with Mycobacterium tuberculosis
Q38869714Dynamics of the membrane-cytoskeleton interface in MHC class II-restricted antigen presentation
Q35749609Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing.
Q43559811Glycosylation signals that separate the trimerization from the mhc class II-binding domain control intracellular degradation of invariant chain
Q51035111Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner
Q45421005Immunogenicity of calreticulin-bound murine leukemia virus glycoprotein gp90.
Q58758033MHC Class II Expression Is Regulated in Dendritic Cells Independently of Invariant Chain Degradation
Q38167996MHC class II antigen presentation by dendritic cells regulated through endosomal sorting
Q35219022Mhc-guided processing: binding of large antigen fragments
Q28611993Presentation of antigens by MHC class II molecules: getting the most out of them
Q33885986Proteolysis in MHC class II antigen presentation: who's in charge?
Q40151915Reconstruction of a pathway of antigen processing and class II MHC peptide capture.
Q36037772Regulation of antigen presentation and cross-presentation in the dendritic cell network: facts, hypothesis, and immunological implications.
Q42132231Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells
Q43867816Specific role for cathepsin S in the generation of antigenic peptides in vivo
Q36674612The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity
Q60944020The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation
Q35821240The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules
Q38174878The lymph self-antigen repertoire
Q34676583The melting pot of the MHC II peptidome

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