| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1006776093 |
| P356 | DOI | 10.1007/S00430-016-0454-1 |
| P698 | PubMed publication ID | 27048482 |
| P50 | author | Rafał Seredyński | Q87638119 |
| P2093 | author name string | Jan Gutowicz | |
| Mateusz Kędzior | |||
| P2860 | cites work | Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion | Q22000757 |
| Evolutionary families of peptidases | Q24527684 | ||
| L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L | Q24531160 | ||
| Molecular and biotechnological aspects of microbial proteases | Q24548591 | ||
| The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction | Q24556546 | ||
| Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment | Q24561952 | ||
| MEROPS: the database of proteolytic enzymes, their substrates and inhibitors | Q24623108 | ||
| An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs | Q24646704 | ||
| Bacterial alpha2-macroglobulins: colonization factors acquired by horizontal gene transfer from the metazoan genome? | Q24804769 | ||
| Human primary osteoclasts: in vitro generation and applications as pharmacological and clinical assay | Q24806517 | ||
| Cysteine cathepsins: from structure, function and regulation to new frontiers | Q26860406 | ||
| Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion | Q27230072 | ||
| Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex | Q27620728 | ||
| Crystal structure of the apoptotic suppressor CrmA in its cleaved form | Q27625472 | ||
| Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex | Q27630750 | ||
| Crystal structure of Stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases | Q27640485 | ||
| The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease | Q27641705 | ||
| The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family | Q27644771 | ||
| Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin | Q27652954 | ||
| Versatile Loops in Mycocypins Inhibit Three Protease Families | Q27657876 | ||
| Structure of a bacterial α2-macroglobulin reveals mimicry of eukaryotic innate immunity | Q27695619 | ||
| X-ray crystallographic structure of a papain-leupeptin complex | Q27732072 | ||
| Crystal structure of human osteoclast cathepsin K complex with E-64 | Q27734783 | ||
| Archaea associated with human surfaces: not to be underestimated | Q28085673 | ||
| Transglutaminase 2: an enigmatic enzyme with diverse functions | Q28205648 | ||
| Irreversible inhibitors of serine, cysteine, and threonine proteases | Q28217093 | ||
| Structure of papain | Q28255054 | ||
| Cellular functions of tissue transglutaminase | Q28260600 | ||
| Cysteine peptidases of kinetoplastid parasites | Q37887589 | ||
| Cruzain : the path from target validation to the clinic | Q37887591 | ||
| Inhibitors of cathepsin K: a patent review (2004 - 2010). | Q37933395 | ||
| Cystatins in immune system | Q38079586 | ||
| Transglutaminase as a therapeutic target for celiac disease | Q38269678 | ||
| Inhibition of chymotrypsin- and subtilisin-like serine proteases with Tk-serpin from hyperthermophilic archaeon Thermococcus kodakaraensis | Q38339032 | ||
| Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study | Q39671546 | ||
| Candida albicans produces a cystatin-type cysteine proteinase inhibitor | Q39935408 | ||
| Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways | Q39986102 | ||
| Recombinant cathepsin S propeptide attenuates cell invasion by inhibition of cathepsin L-like proteases in tumor microenvironment | Q40001461 | ||
| Alpha 2-macroglobulin | Q40103351 | ||
| In vitro prevention of cell-mediated xeno-graft rejection via the Fas/FasL-pathway in CrmA-transducted porcine kidney cells | Q40809405 | ||
| Baculovirus p35 and Z-VAD-fmk inhibit thapsigargin-induced apoptosis of breast cancer cells | Q41091177 | ||
| The papain inhibitor (SPI) of Streptomyces mobaraensis inhibits bacterial cysteine proteases and is an antagonist of bacterial growth. | Q41441223 | ||
| Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes | Q41515448 | ||
| Trichocystatin-2 (TC-2): an endogenous inhibitor of cysteine proteinases in Trichomonas vaginalis is associated with TvCP39. | Q41748529 | ||
| The cathepsin L of Toxoplasma gondii (TgCPL) and its endogenous macromolecular inhibitor, toxostatin | Q41786335 | ||
| Molecular docking of cathepsin L inhibitors in the binding site of papain | Q41889166 | ||
| Inactivation of papain by antithrombin due to autolytic digestion: a model of serpin inactivation of cysteine proteinases | Q42159081 | ||
| Characterization of the leupeptin-inactivating enzyme from Streptomyces exfoliatus SMF13 which produces leupeptin | Q42159277 | ||
| Papain-like cysteine proteases | Q42169600 | ||
| Protease-inhibitory activities of leupeptin analogues | Q42204244 | ||
| The Cladosporium fulvum virulence protein Avr2 inhibits host proteases required for basal defense. | Q42439452 | ||
| CrmA gene transfer rescued CsA-induced renal cell apoptosis in graft kidney | Q42937716 | ||
| Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis | Q43269533 | ||
| Affinity of Avr2 for tomato cysteine protease Rcr3 correlates with the Avr2-triggered Cf-2-mediated hypersensitive response | Q43485716 | ||
| Inhibition of collagenolytic cathepsins by beta-lactoglobulin in milk and its suppressive effect on bone resorption. | Q43519208 | ||
| Enhanced bystander cytotoxicity of P450 gene-directed enzyme prodrug therapy by expression of the antiapoptotic factor p35. | Q43601113 | ||
| The endolysosomal cysteine cathepsins L and K are involved in macrophage-mediated clearance of Staphylococcus aureus and the concomitant cytokine induction | Q43650853 | ||
| Structure-based design of specific cathepsin inhibitors and their application to protection of bone metastases of cancer cells | Q43857553 | ||
| Effect of codon optimization on expression levels of human cystatin C in Pichia pastoris | Q43907658 | ||
| Overlapping binding sites for trypsin and papain on a Kunitz-type proteinase inhibitor from Prosopis juliflora. | Q44165216 | ||
| Functional conservation of a natural cysteine peptidase inhibitor in protozoan and bacterial pathogens | Q44428880 | ||
| A conserved Streptococcus pyogenes extracellular cysteine protease cleaves human fibronectin and degrades vitronectin | Q44441388 | ||
| Protease inhibitor leupeptin attenuates myocardial stunning in rat heart | Q44712824 | ||
| Inhibition of calpains, by treatment with leupeptin, improves motoneuron survival and muscle function in models of motoneuron degeneration | Q44828699 | ||
| Reduction of experimental human fibrosarcoma lung metastasis in mice by adenovirus-mediated cystatin C overexpression in the host | Q44837416 | ||
| Gene transfer of baculoviral p35 by adenoviral vector protects human cerebral neurons from apoptosis | Q45016128 | ||
| Mechanism of Association of a Specific Aldehyde Inhibitor, Leupeptin, with Bovine Trypsin1 | Q45154584 | ||
| A comparison of staphostatin B with standard mechanism serine protease inhibitors | Q45219871 | ||
| Biosynthesis, localization, and processing of falcipain cysteine proteases of Plasmodium falciparum | Q45234045 | ||
| Chagasin, the endogenous cysteine-protease inhibitor of Trypanosoma cruzi, modulates parasite differentiation and invasion of mammalian cells | Q45267339 | ||
| Molecular evolution of daphnia immunity genes: polymorphism in a gram-negative binding protein gene and an alpha-2-macroglobulin gene | Q45857334 | ||
| CrmA gene expression protects mice against concanavalin-A-induced hepatitis by inhibiting IL-18 secretion and hepatocyte apoptosis | Q45864989 | ||
| Prolongation of transgene expression by coexpression of cytokine response modifier a in rodent liver after adenoviral gene transfer | Q45883755 | ||
| Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex. | Q46026102 | ||
| Identification of EhICP1, a chagasin-like cysteine protease inhibitor of Entamoeba histolytica | Q46367406 | ||
| Cladosporium Avr2 inhibits tomato Rcr3 protease required for Cf-2-dependent disease resistance. | Q46450242 | ||
| Leupeptin-sensitive proteases involved in cell survival after X-ray irradiation in human RSa cells | Q46553518 | ||
| Fungal effector protein AVR2 targets diversifying defense-related cys proteases of tomato | Q46616039 | ||
| Fighting an enemy within: cytoplasmic inhibitors of bacterial cysteine proteases. | Q46620016 | ||
| SpeB-Spi: a novel protease-inhibitor pair from Streptococcus pyogenes | Q46620020 | ||
| Cathepsin B inhibitory activities of phthalates isolated from a marine Pseudomonas strain | Q46741636 | ||
| Alpha2-macroglobulin does not function as a C3 homologue in the plasma hemolytic system of the American horseshoe crab, Limulus | Q47770681 | ||
| WF14865A and B, new cathepsins B and L inhibitors produced by Aphanoascus fulvescens. I. Taxonomy, production, purification and biological properties | Q48747041 | ||
| WF14861, a new cathepsins B and L inhibitor produced by Colletotrichum sp. I. Taxonomy, production, purification and structure elucidation | Q48759994 | ||
| Leupeptin, a calpain inhibitor, protects inner ear hair cells from aminoglycoside ototoxicity. | Q50464679 | ||
| Inhibitory activity against papain, a CA1 cysteine peptidase, in Saccharomycetaceae. | Q51133255 | ||
| Extracellular proteolytic enzymes of filamentous fungi. | Q52566137 | ||
| Serine and cysteine proteases are translocated to similar extents upon formation of covalent complexes with serpins. Fluorescence perturbation and fluorescence resonance energy transfer mapping of the protease binding site in CrmA complexes with gra | Q53584976 | ||
| Anti-protease and Immunomodulatory Activities of Bacteria Associated with Caribbean Sponges | Q57846727 | ||
| CA074 methyl ester: a proinhibitor for intracellular cathepsin B | Q67587602 | ||
| Potent slow-binding inhibition of cathepsin B by its propeptide | Q67974285 | ||
| Inhibition of calpain in intact platelets by the thiol protease inhibitor E-64d | Q69329203 | ||
| Bacterial expression of human cysteine proteinase inhibitor stefin A | Q69549767 | ||
| Isolation and characterization of new thiol protease inhibitors estatins A and B | Q69751767 | ||
| Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro | Q70136099 | ||
| E-64 [L-trans-epoxysuccinyl-leucyl-amido(4-guanidino)butane] and related epoxides as inhibitors of cysteine proteinases | Q70236431 | ||
| Inhibition studies of some serine and thiol proteinases by new leupeptin analogues | Q70672494 | ||
| Potent inhibitors of cysteine proteases from the marine fungus Microascus longirostris | Q71105363 | ||
| Inhibitions by E-64 derivatives of rat liver cathepsin B and cathepsin L in vitro and in vivo | Q71479486 | ||
| Leupeptin and E-64, inhibitors of cysteine proteinases, prevent gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts | Q72202550 | ||
| Cathestatins, new cysteine protease inhibitors produced by Penicillium citrinum | Q72276077 | ||
| Physiological roles of leupeptin and extracellular proteases in mycelium development of Streptomyces exfoliatus SMF13 | Q72293764 | ||
| Leupeptins, new protease inhibitors from Actinomycetes | Q72484077 | ||
| Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo | Q73077056 | ||
| Synthesis of peptide aldehyde derivatives as selective inhibitors of human cathepsin L and their inhibitory effect on bone resorption | Q77449793 | ||
| Structural basis of inhibition of cysteine proteases by E-64 and its derivatives | Q77917019 | ||
| Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice | Q79834386 | ||
| Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer | Q80726283 | ||
| MEROPS: the peptidase database | Q81573212 | ||
| Overexpression of stefin A in human esophageal squamous cell carcinoma cells inhibits tumor cell growth, angiogenesis, invasion, and metastasis | Q81639153 | ||
| Degradation of fibrinogen and collagen by staphopains, cysteine proteases released from Staphylococcus aureus | Q82475044 | ||
| Cryptostatin, a chagasin-family cysteine protease inhibitor of Cryptosporidium parvum | Q83736470 | ||
| A novel transglutaminase substrate from Streptomyces mobaraensis inhibiting papain-like cysteine proteases | Q84472165 | ||
| Inhibition of mammalian cathepsins by Plesiomonas shigelloides | Q94505689 | ||
| Multifunctional role of plant cysteine proteinases | Q28284726 | ||
| Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease | Q28285644 | ||
| In support of the trap hypothesis. Chymotrypsin is not rigidly held in its complex with human alpha 2-macroglobulin | Q28338507 | ||
| Cathepsin B localizes to plasma membrane caveolae of differentiating myoblasts and is secreted in an active form at physiological pH | Q28573039 | ||
| Leupeptin inhibits ventilator-induced diaphragm dysfunction in rats | Q28575964 | ||
| A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor | Q28592058 | ||
| Cladosporium fulvum overcomes Cf-2-mediated resistance by producing truncated AVR2 elicitor proteins | Q30839223 | ||
| Phylogenomic analysis of the cystatin superfamily in eukaryotes and prokaryotes | Q30888032 | ||
| A Phytophthora infestans cystatin-like protein targets a novel tomato papain-like apoplastic protease | Q31073721 | ||
| Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases | Q31151222 | ||
| Suppression of gingival inflammation induced by Porphyromonas gingivalis in rats by leupeptin | Q32177130 | ||
| Sequence conservation in the chagasin family suggests a common trend in cysteine proteinase binding by unrelated protein inhibitors | Q33183985 | ||
| Viral cystatin evolution and three-dimensional structure modelling: a case of directional selection acting on a viral protein involved in a host-parasitoid interaction | Q33368470 | ||
| Macrocypins, a family of cysteine protease inhibitors from the basidiomycete Macrolepiota procera | Q33493184 | ||
| Vaccinia virus protein F1L is a caspase-9 inhibitor | Q33648434 | ||
| Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis | Q33717065 | ||
| A superfamily of archaeal, bacterial, and eukaryotic proteins homologous to animal transglutaminases | Q33871440 | ||
| Clitocypin, a new type of cysteine proteinase inhibitor from fruit bodies of mushroom clitocybe nebularis. | Q33896708 | ||
| A virus essential for insect host-parasite interactions encodes cystatins. | Q33908903 | ||
| The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K. | Q34009651 | ||
| Antipain, a new protease inhibitor isolated from actinomycetes | Q34052364 | ||
| Everything in moderation: archaea as 'non-extremophiles'. | Q34068342 | ||
| Identification, characterization and localization of chagasin, a tight-binding cysteine protease inhibitor in Trypanosoma cruzi. | Q34102897 | ||
| Identification of a novel maturation mechanism and restricted substrate specificity for the SspB cysteine protease of Staphylococcus aureus. | Q34147146 | ||
| Families of cysteine peptidases. | Q34317817 | ||
| Staphopains modulate Staphylococcus aureus biofilm integrity. | Q34353371 | ||
| Immune response of Anopheles gambiae to the early sporogonic stages of the human malaria parasite Plasmodium falciparum | Q34427362 | ||
| Cysteine proteases of parasitic organisms | Q34534692 | ||
| Transglutaminases: multifunctional cross‐linking enzymes that stabilize tissues | Q34547164 | ||
| Crystal structure of chagasin, the endogenous cysteine-protease inhibitor from Trypanosoma cruzi. | Q34570251 | ||
| Aeropin from the extremophile Pyrobaculum aerophilum bypasses the serpin misfolding trap | Q34652212 | ||
| Cathepsin L activity controls adipogenesis and glucose tolerance | Q34654358 | ||
| Sexual development in Plasmodium parasites: knowing when it's time to commit | Q34672315 | ||
| Thiol-dependent cathepsins: pathophysiological implications and recent advances in inhibitor design | Q34754118 | ||
| Prevention of apoptosis by a baculovirus gene during infection of insect cells | Q34993245 | ||
| Immunomodulatory properties of cystatins | Q35003239 | ||
| Processing and activation of lysosomal proteinases | Q35055169 | ||
| Transglutaminases: crosslinking enzymes with pleiotropic functions | Q35058528 | ||
| Characterization of macroautophagic flux in vivo using a leupeptin-based assay | Q35079032 | ||
| Cysteine protease inhibitors containing small rings | Q35181404 | ||
| Structural determinants of caspase-9 inhibition by the vaccinia virus protein, F1L | Q35182960 | ||
| Functions of Propeptide Parts in Cysteine Proteases | Q35552225 | ||
| Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division | Q35617768 | ||
| Repurposing FDA approved drugs against the human fungal pathogen, Candida albicans | Q35657134 | ||
| Cysteine proteases as disease markers | Q35693690 | ||
| Functional and Structural Characterization of the Antiphagocytic Properties of a Novel Transglutaminase from Streptococcus suis. | Q35905346 | ||
| Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease | Q35916157 | ||
| Proteinaceous cysteine protease inhibitors | Q36072062 | ||
| Codon preference optimization increases prokaryotic cystatin C expression | Q36316406 | ||
| Subterfuge and manipulation: type III effector proteins of phytopathogenic bacteria | Q36497116 | ||
| Cathepsin B inhibition limits bone metastasis in breast cancer | Q36511851 | ||
| Inhibitors of cathepsin B. | Q36570016 | ||
| An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif | Q36686481 | ||
| Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease | Q36740290 | ||
| Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytes. | Q36744868 | ||
| Two decades of thyroglobulin type-1 domain research. | Q36988309 | ||
| Cysteine cathepsin proteases as pharmacological targets in cancer | Q37013943 | ||
| Papain-like cysteine proteases: key players at molecular battlefields employed by both plants and their invaders. | Q37244403 | ||
| Fungal effector proteins | Q37462879 | ||
| Baculovirus P35 protein: an overview of its applications across multiple therapeutic and biotechnological arenas | Q37615213 | ||
| Cystatin superfamily | Q37696036 | ||
| Plant cystatins | Q37766012 | ||
| Yersinia enterocolitica outer protein T (YopT). | Q37831516 | ||
| Fungal proteases and their pathophysiological effects | Q37831836 | ||
| Papain-like proteases of Staphylococcus aureus | Q37887583 | ||
| The lysine-specific gingipain of Porphyromonas gingivalis : importance to pathogenicity and potential strategies for inhibition | Q37887585 | ||
| Falcipains and other cysteine proteases of malaria parasites | Q37887586 | ||
| Entamoeba histolytica cathepsin-like enzymes : interactions with the host gut. | Q37887588 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 275-296 | |
| P577 | publication date | 2016-04-05 | |
| P1433 | published in | Medical Microbiology and Immunology | Q15760239 |
| P1476 | title | Microbial inhibitors of cysteine proteases | |
| P478 | volume | 205 |
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