Caging the uncageable: using metal complex release for photochemical control over irreversible inhibition

scientific article published on 6 October 2016

Caging the uncageable: using metal complex release for photochemical control over irreversible inhibition is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1039/C6CC07083C
P932PMC publication ID5076553
P698PubMed publication ID27711349

P2093author name stringClaudia Turro
Izabela Podgorski
Jeremy J Kodanko
Jessica K White
Matthew Huisman
Veronica G Lewalski
P2860cites workCathepsin L is significantly associated with apoptosis and plaque destabilization in human atherosclerosisQ24314942
Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complexQ27620728
Irreversible inhibitors of serine, cysteine, and threonine proteasesQ28217093
Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinaseQ29617738
Unusually efficient pyridine photodissociation from Ru(II) complexes with sterically bulky bidentate ancillary ligandsQ30598699
Light activation of a cysteine protease inhibitor: caging of a peptidomimetic nitrile with Ru(II)(bpy)2Q33635076
Photoactivated chemotherapy (PACT): the potential of excited-state d-block metals in medicine.Q34105908
The resurgence of covalent drugsQ34174891
Structure-based development of specific inhibitors for individual cathepsins and their medical applicationsQ34598268
Cathepsin L targeting in cancer treatment.Q36218199
New Ru(II) complexes for dual photoreactivity: ligand exchange and (1)O2 generationQ36533554
Photoremovable protecting groups in chemistry and biology: reaction mechanisms and efficacy.Q36570458
Principles and applications of the photochemical control of cellular processes.Q37158588
Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds.Q37237208
Development of nitrile-based peptidic inhibitors of cysteine cathepsinsQ37694669
Cathepsins and their involvement in immune responsesQ37774592
Photoactivated inhibition of cathepsin K in a 3D tumor modelQ38791995
A luminescent ruthenium(II) complex for light-triggered drug release and live cell imaging.Q38845855
Design strategies to improve the sensitivity of photoactive metal carbonyl complexes (photoCORMs) to visible light and their potential as CO-donors to biological targetsQ39162940
A luminescent and biocompatible photoCORM.Q39257040
Cellular toxicity induced by the photorelease of a caged bioactive molecule: design of a potential dual-action Ru(II) complexQ43497813
A new strategy for neurochemical photodelivery: metal-ligand heterolytic cleavageQ44284606
Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivoQ73077056
P433issue85
P407language of work or nameEnglishQ1860
P304page(s)12590-12593
P577publication date2016-10-06
P1433published inChemical CommunicationsQ426303
P1476titleCaging the uncageable: using metal complex release for photochemical control over irreversible inhibition
P478volume52

Reverse relations

cites work (P2860)
Q55474273Affinity-Enhanced Luminescent Re(I)- and Ru(II)-Based Inhibitors of the Cysteine Protease Cathepsin L.
Q57046763Catch and Release Photosensitizers: Combining Dual Action Ruthenium Complexes with Protease Inactivation for Targeting Invasive Cancers
Q48094567DFT Investigation of Ligand Photodissociation in [RuII(tpy)(bpy)(py)]2+ and [RuII(tpy)(Me2bpy)(py)]2+ Complexes.
Q90618948Designing Photolabile Ruthenium Polypyridyl Crosslinkers for Hydrogel Formation and Multiplexed, Visible-light Degradation
Q64988533Photoactivation of imatinib-antibody conjugate using low-energy visible light from Ru(ii)-polypyridyl cages.
Q60960387Photochemical resolution of a thermally inert cyclometalated Ru(phbpy)(N-N)(sulfoxide)+ complex
Q55365212Ru(II) Polypyridyl Complexes Derived from Tetradentate Ancillary Ligands for Effective Photocaging.
Q58547514Ru(ii) complexes with diazine ligands: electronic modulation of the coordinating group is key to the design of "dual action" photoactivated agents
Q50091548Ru(ii) polypyridyl complexes as photocages for bioactive compounds containing nitriles and aromatic heterocycles

Search more.