Structure-based development of cathepsin L inhibitors and therapeutic applications for prevention of cancer metastasis and cancer-induced osteoporosis.

scientific article published on January 2002

Structure-based development of cathepsin L inhibitors and therapeutic applications for prevention of cancer metastasis and cancer-induced osteoporosis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0065-2571(01)00060-7
P8608Fatcat IDrelease_rdl3z7tz3jcaxp43r5atbnz7aq
P698PubMed publication ID12123713

P50authorHideaki TsugeQ46648414
P2093author name stringN Katunuma
M Fukushima
M Nukatsuka
P2860cites workBone loss induced by cancer treatment and its managementQ77312714
Synthesis of peptide aldehyde derivatives as selective inhibitors of human cathepsin L and their inhibitory effect on bone resorptionQ77449793
Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitorsQ27730182
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesisQ28293009
Response to intravenous bisphosphonate therapy in hypercalcaemic patients with and without bone metastases: the role of parathyroid hormone-related proteinQ36079478
A simple method to assess osteoclast-mediated bone resorption using unfractionated bone cellsQ39100887
Overview of bisphosphonatesQ41637516
Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures.Q54137269
Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not DemineralizationQ57272396
Effects of dichloromethylene diphosphonate on the osteolytic and osteoplastic effects of rat prostate adenocarcinoma cellsQ69977844
Participation of cathepsin L on bone resorptionQ70670024
Prolongation of survival period and improvement of cancer cachexia by long-term administration of UFTQ71148343
Comparative study of inhibitory effects by murine interferon ? and a new bisphosphonate (alendronate) in hypercalcemic, nude mice bearing human tumor (LJC-1-JCK)Q71649346
Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivoQ73077056
Cathepsin K antisense oligodeoxynucleotide inhibits osteoclastic bone resorptionQ73174502
Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivoQ73673392
Regulation of collagenolytic protease secretion through c-Src in osteoclastsQ73937025
Regulation of collagenolytic cysteine protease synthesis by estrogen in osteoclastsQ74015246
Distinct roles of cathepsin K and cathepsin L in osteoclastic bone resorptionQ74095795
Effects of YM175, a new-generation bisphosphonate, on hypercalcemia induced by tumor-derived bone resorbing factors in ratsQ74441299
Bone metastases--the clinical problemQ77312680
P407language of work or nameEnglishQ1860
P921main subjectcancer metastasisQ120912394
P304page(s)159-172
P577publication date2002-01-01
P1433published inAdvances in Enzyme RegulationQ15756443
P1476titleStructure-based development of cathepsin L inhibitors and therapeutic applications for prevention of cancer metastasis and cancer-induced osteoporosis
P478volume42

Reverse relations

cites work (P2860)
Q55474273Affinity-Enhanced Luminescent Re(I)- and Ru(II)-Based Inhibitors of the Cysteine Protease Cathepsin L.
Q38025001Cancer-associated lysosomal changes: friends or foes?
Q37724780Cathepsin L in metastatic bone disease: therapeutic implications
Q36218199Cathepsin L targeting in cancer treatment.
Q36650691Protease inhibitors and their peptidomimetic derivatives as potential drugs

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