| scholarly article | Q13442814 |
| P50 | author | William Vainchenker | Q3569009 |
| Guido Kroemer | Q19508945 | ||
| Laurence Zitvogel | Q28317098 | ||
| Ilio Vitale | Q28317127 | ||
| Maria Castedo | Q70911078 | ||
| Philippe Dessen | Q90281812 | ||
| Noelia Casares | Q93038508 | ||
| Vladimir Lazăr | Q108760737 | ||
| Nazanine Modjtahedi | Q114415898 | ||
| Arnaud Coquelle | Q114777979 | ||
| Sonia Vivet | Q114777980 | ||
| Marie O Pequignot | Q114777981 | ||
| Shahul Mouhamad | Q114777982 | ||
| Elise Schmitt | Q114777983 | ||
| P2093 | author name string | Carmen Garrido | |
| Audrey Kauffmann | |||
| Alexandre Valent | |||
| P2860 | cites work | The Hallmarks of Cancer | Q221226 |
| PUMA induces the rapid apoptosis of colorectal cancer cells | Q24291462 | ||
| PUMA, a novel proapoptotic gene, is induced by p53 | Q24291463 | ||
| Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells | Q24536196 | ||
| PUMA mediates the apoptotic response to p53 in colorectal cancer cells | Q24550772 | ||
| EMBOSS: the European Molecular Biology Open Software Suite | Q27860491 | ||
| Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells | Q27860926 | ||
| Polyploids require Bik1 for kinetochore–microtubule attachment | Q27937672 | ||
| Surfing the p53 network | Q28032484 | ||
| 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage | Q28145962 | ||
| Apoptosis in the pathogenesis and treatment of disease | Q28235731 | ||
| From polyploidy to aneuploidy, genome instability and cancer | Q28237393 | ||
| Cell death: critical control points | Q28240722 | ||
| Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells | Q28361124 | ||
| Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death | Q28363890 | ||
| Live or let die: the cell's response to p53 | Q29547663 | ||
| The pathophysiology of mitochondrial cell death | Q29547893 | ||
| Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells | Q29617924 | ||
| Role of BAX in the apoptotic response to anticancer agents | Q31523620 | ||
| Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope | Q34090039 | ||
| The influence of resection and aneuploidy on mortality in oral leukoplakia | Q34311848 | ||
| Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors | Q34314899 | ||
| The combination of genetic instability and clonal expansion predicts progression to esophageal adenocarcinoma | Q34360062 | ||
| Quantitation of mitochondrial alterations associated with apoptosis | Q34693198 | ||
| Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion | Q34831438 | ||
| Ways of dying: multiple pathways to apoptosis. | Q35560936 | ||
| Cytochrome C-mediated apoptosis | Q35799945 | ||
| Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint | Q35938685 | ||
| Biological implications of cell fusion. | Q36163604 | ||
| Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death. | Q36197250 | ||
| Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1. | Q36280815 | ||
| Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint". | Q36322436 | ||
| The predictive value of p53, p53R2, and p21 for the effect of chemoradiation therapy on oesophageal squamous cell carcinoma | Q36616178 | ||
| Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy. | Q40572671 | ||
| An anti-apoptotic viral protein that recruits Bax to mitochondria | Q40581687 | ||
| Gene expression and mitotic exit induced by microtubule-stabilizing drugs | Q40614304 | ||
| C-myc overexpression and p53 loss cooperate to promote genomic instability | Q40973006 | ||
| Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability | Q44714286 | ||
| Biphasic acute myeloid leukemia with near-tetraploidy and immunophenotypic transformation | Q44813833 | ||
| Molecular phenotype of spontaneously arising 4N (G2-tetraploid) intermediates of neoplastic progression in Barrett's esophagus | Q47745707 | ||
| DNA content as a prognostic marker in patients with oral leukoplakia | Q50673869 | ||
| A p53-dependent mouse spindle checkpoint | Q56445949 | ||
| Further characterisation of the p53 responsive element--identification of new candidate genes for trans-activation by p53 | Q73016679 | ||
| Cell fusion: a hidden enemy? | Q73466854 | ||
| Near-triploidy and near-tetraploidy in hematological malignancies and mutation of the p53 gene | Q75316555 | ||
| Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy | Q80402719 | ||
| p53 deficiency exacerbates pleiotropic mitotic defects, changes in nuclearity and polyploidy in transdifferentiating pancreatic acinar cells | Q81449654 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 2584-2595 | |
| P577 | publication date | 2006-05-04 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Apoptosis regulation in tetraploid cancer cells | |
| P478 | volume | 25 |
| Q54408711 | A four-lane highway to cancer |
| Q37783910 | A novel source of tetraploid cancer cell precursors: telomere insufficiency links aging to oncogenesis |
| Q38429571 | A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial. |
| Q33348538 | A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells |
| Q39087778 | AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53. |
| Q30543669 | ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy |
| Q39159318 | Abnormal mitosis triggers p53-dependent cell cycle arrest in human tetraploid cells. |
| Q30498067 | An automated fluorescence videomicroscopy assay for the detection of mitotic catastrophe |
| Q35535592 | Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma. |
| Q33579079 | Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells |
| Q36340540 | CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells |
| Q52765570 | Caspase 2 in mitotic catastrophe: The terminator of aneuploid and tetraploid cells. |
| Q57082812 | Caspase independence of radio-induced cell death |
| Q26740111 | Cell Fusion in the War on Cancer: A Perspective on the Inception of Malignancy |
| Q35972102 | Cell death signaling and anticancer therapy |
| Q26771165 | Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization |
| Q30549643 | Characterization of novel MPS1 inhibitors with preclinical anticancer activity |
| Q39141464 | Chromosomal Instability as a Driver of Tumor Heterogeneity and Evolution |
| Q53222824 | Chromosomal breaks during mitotic catastrophe trigger γH2AX-ATM-p53-mediated apoptosis |
| Q38855877 | Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells |
| Q57394700 | Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions |
| Q30497160 | Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells |
| Q37778009 | DNA Damage and Polyploidization |
| Q40038486 | DNA damage induces two distinct modes of cell death in ovarian carcinomas |
| Q37116325 | Death receptor pathways mediate targeted and non-targeted effects of ionizing radiations in breast cancer cells. |
| Q40001763 | Deregulation of Cdk2 causes Bim-mediated apoptosis in p53-deficient tumors following actin damage |
| Q35748364 | Dominant negative pleiotrophin induces tetraploidy and aneuploidy in U87MG human glioblastoma cells |
| Q37502273 | Escherichia coli-derived outer membrane vesicles are genotoxic to human enterocyte-like cells |
| Q39279911 | Excess F-actin mechanically impedes mitosis leading to cytokinesis failure in X-linked neutropenia by exceeding Aurora B kinase error correction capacity |
| Q24321782 | FLJ25439, a novel cytokinesis-associated protein, induces tetraploidization and maintains chromosomal stability via enhancing expression of endoplasmic reticulum stress chaperones |
| Q39028802 | GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis |
| Q59017675 | Generation of Immortalised But Unstable Cells after hTERT Introduction in Telomere-Compromised and p53-Deficient vHMECs |
| Q35020487 | Genomic Instability Induced By Human Papillomavirus Oncogenes |
| Q41764481 | Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. |
| Q36447691 | Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer |
| Q35227425 | Illicit survival of cancer cells during polyploidization and depolyploidization |
| Q61851522 | Immune effectors responsible for the elimination of hyperploid cancer cells |
| Q36654387 | Immunosurveillance against tetraploidization-induced colon tumorigenesis |
| Q36304190 | Independent transcriptional reprogramming and apoptosis induction by cisplatin |
| Q27302281 | Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway |
| Q41887009 | Investigating cytokinesis failure as a strategy in cancer therapy |
| Q38172298 | Isogenic radiation resistant cell lines: development and validation strategies. |
| Q39456888 | Karyotypic Aberrations in Oncogenesis and Cancer Therapy |
| Q37777023 | MOS, aneuploidy and the ploidy cycle of cancer cells |
| Q38938572 | MiR-363 sensitizes cisplatin-induced apoptosis targeting in Mcl-1 in breast cancer |
| Q52610466 | Mitotic catastrophe: a mechanism for avoiding genomic instability |
| Q29616161 | Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 |
| Q47843948 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. |
| Q37926477 | Molecular mechanisms of cisplatin resistance |
| Q36562331 | Morphometric analysis of immunoselection against hyperploid cancer cells |
| Q30494172 | Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos. |
| Q50876082 | NQO1 prevents radiation-induced aneuploidy by interacting with Aurora-A. |
| Q39958561 | Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa |
| Q38526539 | Notch activation is associated with tetraploidy and enhanced chromosomal instability in meningiomas |
| Q28544803 | Novel roles for p53 in the genesis and targeting of tetraploid cancer cells |
| Q24631776 | PUMA, a potent killer with or without p53 |
| Q37256726 | Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy |
| Q38900239 | Phosphorylation of myosin II regulatory light chain by ZIP kinase is responsible for cleavage furrow ingression during cell division in mammalian cultured cells |
| Q38121272 | Physiological significance of polyploidization in mammalian cells |
| Q36205846 | Polyploid titan cells produce haploid and aneuploid progeny to promote stress adaptation |
| Q54510509 | Preferential killing of p53-deficient cancer cells by reversine. |
| Q39597313 | Properties of cells with increased resistance to some picornaviruses |
| Q39841523 | Protein expression following gamma-irradiation relevant to growth arrest and apoptosis in colon cancer cells |
| Q37253577 | RABL6A Promotes Oxaliplatin Resistance in Tumor Cells and Is a New Marker of Survival for Resected Pancreatic Ductal Adenocarcinoma Patients. |
| Q34116777 | Radiation-induced cell death mechanisms |
| Q33287956 | Relevance of microRNAs in normal and malignant development, including human testicular germ cell tumours. |
| Q39478063 | Respiration characteristics of mitochondria in parental and giant transformed cells of the murine Nemeth-Kellner lymphoma |
| Q30573152 | Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention |
| Q42378412 | Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2. |
| Q90480415 | Role of Bcl-2 on drug resistance in breast cancer polyploidy-induced spindle poisons |
| Q37630572 | Role of prolonged mitotic checkpoint activation in the formation and treatment of cancer |
| Q36238666 | Selective killing of p53-deficient cancer cells by SP600125. |
| Q38707261 | Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines |
| Q35850149 | Surveillance mechanism linking Bub1 loss to the p53 pathway |
| Q51075833 | Synchronization and Desynchronization of Cells by Interventions on the Spindle Assembly Checkpoint. |
| Q39800101 | Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines |
| Q42446079 | Tetraploid cancer cell precursors in ovarian carcinoma |
| Q39984199 | Tetraploidy and CIN: a dangerous combination |
| Q57662446 | Tetraploidy in cancer and its possible link to aging |
| Q92965735 | The DNA-damage response and nuclear events as regulators of nonapoptotic forms of cell death |
| Q40446144 | The kinetics of p53 activation versus cyclin E accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint |
| Q30535409 | Transgenerational cell fate profiling: a method for the graphical presentation of complex cell cycle alterations |
| Q39929026 | Transient nutlin-3a treatment promotes endoreduplication and the generation of therapy-resistant tetraploid cells |
| Q40088786 | Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia |
| Q36729558 | Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition |
| Q34072697 | p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells |
| Q33766312 | p53 suppresses structural chromosome instability after mitotic arrest in human cells |
| Q35190108 | p53: Guardian of ploidy |
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