| scholarly article | Q13442814 |
| P2093 | author name string | Han Z | |
| Wyche JH | |||
| Bremner TA | |||
| Hendrickson EA | |||
| P2860 | cites work | Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c | Q24309066 |
| A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes | Q28237565 | ||
| Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis | Q28292299 | ||
| Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase | Q28302692 | ||
| Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway | Q28639902 | ||
| Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE | Q29619356 | ||
| Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme | Q34240507 | ||
| Prevention of vertebrate neuronal death by the crmA gene | Q34349314 | ||
| Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice | Q34408475 | ||
| Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death | Q36366579 | ||
| Protease activation during apoptosis: death by a thousand cuts? | Q40459802 | ||
| ICE-related proteases in apoptosis. | Q41099872 | ||
| Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases. | Q41173395 | ||
| Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis | Q41204766 | ||
| Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. | Q41284156 | ||
| Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity | Q43605647 | ||
| ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis | Q47961195 | ||
| FLICE Induced Apoptosis in a Cell-free System | Q58883549 | ||
| P433 | issue | 20 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 13432-13436 | |
| P577 | publication date | 1997-05-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro | |
| P478 | volume | 272 |
| Q42650629 | A kiss of death--proteasome-mediated membrane fusion and programmed cell death in plant defense against bacterial infection |
| Q40632732 | A serine protease is involved in the initiation of DNA damage-induced apoptosis |
| Q39691361 | A switch-on mechanism to activate maize ribosome-inactivating protein for targeting HIV-infected cells |
| Q33833384 | Activation of apoptosis and its inhibition |
| Q73911130 | Aldehyde and phosphinate analogs of glutathione and glutathionylspermidine: potent, selective binding inhibitors of the E. coli bifunctional glutathionylspermidine synthetase/amidase |
| Q36360700 | Alternative splicing of Drosophila Nmnat functions as a switch to enhance neuroprotection under stress |
| Q35058831 | An Uncleavable Procaspase-3 Mutant Has a Lower Catalytic Efficiency but an Active Site Similar to That of Mature Caspase-3 |
| Q46627623 | Anti-inflammatory properties of tianeptine on lipopolysaccharide-induced changes in microglial cells involve toll-like receptor-related pathways |
| Q53598963 | Apoptosis by cyclosporine in mesangial cells. |
| Q73695363 | Apoptosis induced by dithiothreitol in HL-60 cells shows early activation of caspase 3 and is independent of mitochondria |
| Q37099926 | Apoptosis-associated caspase activation assays |
| Q37698147 | Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging. |
| Q40810138 | Bcl-xL blocks transforming growth factor-beta 1-induced apoptosis by inhibiting cytochrome c release and not by directly antagonizing Apaf-1-dependent caspase activation in prostate epithelial cells |
| Q35642101 | Bid-independent mitochondrial activation in tumor necrosis factor alpha-induced apoptosis and liver injury |
| Q44598662 | Bisindolylmaleimide IX is a potent inducer of apoptosis in chronic lymphocytic leukaemic cells and activates cleavage of Mcl-1. |
| Q84880485 | Calcineurin B subunit acts as a potential agent for preventing cardiac ischemia/reperfusion injury |
| Q77896984 | Cascades of mammalian caspase activation in the yeast Saccharomyces cerevisiae |
| Q48932616 | Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis |
| Q24290854 | Caspase activation is required for terminal erythroid differentiation |
| Q40889554 | Caspase inhibitor P35 and inhibitor of apoptosis Op-IAP block in vivo proteolytic activation of an effector caspase at different steps |
| Q35049064 | Caspase inhibitors as anti-inflammatory and antiapoptotic agents. |
| Q40431489 | Caspase-3 can be pseudo-activated by a Ca2+-dependent proteolysis at a non-canonical site. |
| Q48149085 | Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP. |
| Q43202448 | Caspase-3-like activity determines the type of cell death following ionizing radiation in MOLT-4 human leukaemia cells |
| Q37446194 | Caspase-9 activation by the apoptosome is not required for fas-mediated apoptosis in type II Jurkat cells |
| Q43732818 | Caspase-9 processing by caspase-3 via a feedback amplification loop in vivo |
| Q55511537 | Caspase-independent cell death does not elicit a proliferative response in melanoma cancer cells. |
| Q40424967 | Caspases activation in hyperthermia-induced stimulation of TRAIL apoptosis. |
| Q24647389 | Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis |
| Q58289992 | Characterization of Caspase Processing and Activation in HL-60 Cell Cytosol Under Cell-free Conditions |
| Q28546869 | Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound |
| Q33869177 | Cif (Cytochrome c efflux-inducing factor) activity is regulated by Bcl-2 and caspases and correlates with the activation of Bid. |
| Q40298735 | Cis-hydroxyproline-induced inhibition of pancreatic cancer cell growth is mediated by endoplasmic reticulum stress |
| Q40963135 | Cleavage of transcription factor SP1 by caspases during anti-IgM-induced B-cell apoptosis |
| Q73704701 | Co-localization of active caspase-3 and DNA fragmentation (TUNEL) in normal and hyperthermia-induced abnormal mouse development |
| Q44526029 | Concurrent upregulation of endogenous proapoptotic and antiapoptotic factors in failing human hearts |
| Q64975715 | Countering TRAIL Resistance in Melanoma. |
| Q57243254 | Critical role of mitochondria-mediated apoptosis for JNJ-26481585-induced antitumor activity in rhabdomyosarcoma |
| Q27642657 | Crystal structure of an invertebrate caspase |
| Q34309056 | Cytoprotective effects of a cyclic RGD peptide in steatotic liver cold ischemia and reperfusion injury |
| Q40908454 | Cytoskeletal disruption induces T cell apoptosis by a caspase-3 mediated mechanism |
| Q92229529 | Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide |
| Q43902939 | Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells |
| Q36375602 | Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells |
| Q43963394 | Effect of AT(1) receptor blockade on cardiac apoptosis in angiotensin II-induced hypertension |
| Q34789025 | Effect of serum containing Jinmaitong Capsule on rats' Schwann cell apoptosis induced by high glucose concentration |
| Q38739992 | Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype |
| Q39567967 | Glucocorticoid receptors take part in the apoptotic process of human lens epithelial cells, but the glucocorticoid receptor antagonist RU486 does not rescue the cells fully |
| Q46112305 | Granzyme release and caspase activation in activated human T-lymphocytes. |
| Q57065814 | HCMV Infection and Apoptosis: How Do Monocytes Survive HCMV Infection? |
| Q30389783 | Highly pathogenic avian influenza H5N1 virus delays apoptotic responses via activation of STAT3. |
| Q36736892 | Human Cytomegalovirus Promotes Survival of Infected Monocytes via a Distinct Temporal Regulation of Cellular Bcl-2 Family Proteins |
| Q36276722 | Human cytomegalovirus stimulates monocyte-to-macrophage differentiation via the temporal regulation of caspase 3. |
| Q33261810 | IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells |
| Q38902471 | Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma |
| Q33911071 | Impaired Akt activity down-modulation, caspase-3 activation, and apoptosis in cells expressing a caspase-resistant mutant of RasGAP at position 157 |
| Q46802250 | Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria |
| Q43900075 | Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3. |
| Q40123719 | Labeling of apoptotic JURL-MK1 cells by fluorescent caspase-3 inhibitor FAM-DEVD-fmk occurs mainly at site(s) different from caspase-3 active site |
| Q48877474 | Leczyme |
| Q21563509 | Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability |
| Q33724036 | MicroRNA-98 rescues proliferation and alleviates ox-LDL-induced apoptosis in HUVECs by targeting LOX-1 |
| Q35834606 | Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis |
| Q33799742 | Mitogen-activated protein kinase-activated protein kinase 2 mediates apoptosis during lung vascular permeability by regulating movement of cleaved caspase 3 |
| Q44409476 | Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers |
| Q55510382 | NGAL protects against endotoxin-induced renal tubular cell damage by suppressing apoptosis. |
| Q93105091 | Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity |
| Q40571359 | Ochratoxin A induces apoptosis in human lymphocytes through down regulation of Bcl-xL. |
| Q43227881 | Okadaic acid induces DNA fragmentation via caspase-3-dependent and caspase-3-independent pathways in Chinese hamster ovary (CHO)-K1 cells |
| Q40714385 | Olecular mechanism underlying the myeloperoxidase induced apoptosis of HUVEC-12 cells |
| Q34826141 | Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS. |
| Q39867609 | Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway |
| Q28237935 | PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibition |
| Q37095286 | PI3K-dependent upregulation of Mcl-1 by human cytomegalovirus is mediated by epidermal growth factor receptor and inhibits apoptosis in short-lived monocytes |
| Q22253392 | Palmitoyl protein thioesterase 1 protects against apoptosis mediated by Ras-Akt-caspase pathway in neuroblastoma cells |
| Q39180303 | Parathyroid hormone-related protein regulates integrin α6 and β4 levels via transcriptional and post-translational pathways |
| Q36121738 | Photofrin binds to procaspase-3 and mediates photodynamic treatment-triggered methionine oxidation and inactivation of procaspase-3. |
| Q74028194 | Prediction of the tertiary structure and substrate binding site of caspase-8 |
| Q34275921 | Proteinase families and their inhibitors |
| Q41038385 | Proteolytic cleavage of HsRad51 during apoptosis |
| Q33807797 | Quantitative analysis of pathways controlling extrinsic apoptosis in single cells |
| Q28354545 | Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes |
| Q38929164 | Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia |
| Q45269805 | Regulation of monocyte apoptosis by the protein kinase Cdelta-dependent phosphorylation of caspase-3. |
| Q48088809 | Relative level of expression of Bax and Bcl-XL determines the cellular fate of apoptosis/necrosis induced by the overexpression of Bax. |
| Q37164382 | Secondary necrotic neutrophils release interleukin-16C and macrophage migration inhibitory factor from stores in the cytosol. |
| Q44038797 | Selective inhibition of dipeptidyl peptidase I, not caspases, prevents the partial processing of procaspase-3 in CD3-activated human CD8(+) T lymphocytes |
| Q37160973 | Shift from apoptotic to necrotic cell death during human papillomavirus-induced transformation of keratinocytes |
| Q39714230 | Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation |
| Q40399595 | Sodium butyrate sensitizes human glioma cells to TRAIL-mediated apoptosis through inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. |
| Q38073714 | Spinal muscular atrophy and the antiapoptotic role of survival of motor neuron (SMN) protein |
| Q40141181 | Subunit S5a of the 26S proteasome is regulated by antiapoptotic signals |
| Q38446898 | Surviving apoptosis: life-death signaling in single cells. |
| Q28476828 | Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma |
| Q51302970 | Synergistic protective effect of folic acid and vitamin B12 against nicotine-induced oxidative stress and apoptosis in pancreatic islets of the rat. |
| Q54022088 | TGF-beta induces the expression of the FLICE-inhibitory protein and inhibits Fas-mediated apoptosis of microglia. |
| Q36067201 | TIMP-1 deficiency leads to lethal partial hepatic ischemia and reperfusion injury |
| Q39314142 | TRAIL resistance in human neuroblastoma SK-N-AS cells is dependent on protein kinase C and involves inhibition of caspase-3 proteolytic processing |
| Q43136832 | The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing |
| Q78181058 | The activity of caspase-3-like proteases is elevated during the development of colorectal carcinoma |
| Q24532851 | The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases |
| Q61443242 | The prodomain of caspase-3 regulates its own removal and caspase activation |
| Q40872725 | The short prodomain influences caspase-3 activation in HeLa cells |
| Q88453324 | Thick Filament Protein Network, Functions, and Disease Association |
| Q37285124 | Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis |
| Q38862080 | Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways |
| Q87249480 | U0126, an Inhibitor of MEK1/2, Increases Tumor Necrosis Factor-α-Induced Apoptosis, but not Interleukin-6 Induced Apoptosis in C-28/I2 Human Chondrocytes |
| Q46908404 | Up-regulation of NFATc4 involves in neuronal apoptosis following intracerebral hemorrhage |
| Q36371312 | XIAP-mediated caspase inhibition in Hodgkin's lymphoma-derived B cells |
| Q40255749 | Zebrafish caspase-3: molecular cloning, characterization, crystallization and phylogenetic analysis |
| Q35843434 | miR-155 targets Caspase-3 mRNA in activated macrophages |
| Q54104034 | p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells. |
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