| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1146/ANNUREV.PHARMTOX.43.100901.140251 |
| P8608 | Fatcat ID | release_pvc4sjkh4nbpjmmrs55bn7emvi |
| P3181 | OpenCitations bibliographic resource ID | 3069171 |
| P698 | PubMed publication ID | 12171978 |
| P2093 | author name string | Laurence S Kaminsky | |
| Laurence S. Kaminsky | |||
| Xinxin Ding | |||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | toxicity | Q274160 |
| P304 | page(s) | 149-173 | |
| 149-73 | |||
| P577 | publication date | 2003-04-01 | |
| P1433 | published in | Annual Review of Pharmacology and Toxicology | Q567365 |
| P1476 | title | Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts | |
| HUMAN EXTRAHEPATIC CYTOCHROMES P450: Function in Xenobiotic Metabolism and Tissue-Selective Chemical Toxicity in the Respiratory and Gastrointestinal Tracts | |||
| P478 | volume | 43 |
| Q33745362 | 3-Methylindole metabolites induce lung CYP1A1 and CYP2F1 enzymes by AhR and non-AhR mechanisms, respectively |
| Q91588465 | A Pilot Study towards the Impact of Type 2 Diabetes on the Expression and Activities of Drug Metabolizing Enzymes and Transporters in Human Duodenum |
| Q33511275 | A possible link between iron deficiency and gastrointestinal carcinogenesis |
| Q33662661 | A practical strategy to design and develop an isoform-specific fluorescent probe for a target enzyme: CYP1A1 as a case study. |
| Q38132657 | A review of the toxicology and pathology of the gastrointestinal tract |
| Q24762873 | A review of the volatiles from the healthy human body |
| Q37604428 | A role for cytochrome b5 in the In vivo disposition of anticancer and cytochrome P450 probe drugs in mice |
| Q37707721 | A targeted proteomics approach for profiling murine cytochrome P450 expression |
| Q51088643 | A transit compartment model unmasks OxyContin's reflective pharmacokinetics from urine measurements in humans. |
| Q91178769 | Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability |
| Q38795261 | Activation of transcription factors in human bronchial epithelial cells exposed to aqueous extracts of mainstream cigarette smoke in vitro. |
| Q29347041 | Age-related changes in the mRNA levels of CYP1A1, CYP2B1/2 and CYP3A1 isoforms in rat small intestine |
| Q46110077 | Age-specific pulmonary cytochrome P-450 3A1 expression in postnatal and adult rats |
| Q38823495 | An in vitro system for measuring genotoxicity mediated by human CYP3A4 in Saccharomyces cerevisiae |
| Q37104008 | An intestinal epithelium-specific cytochrome P450 (P450) reductase-knockout mouse model: direct evidence for a role of intestinal p450s in first-pass clearance of oral nifedipine |
| Q28079725 | An update on the role of intestinal cytochrome P450 enzymes in drug disposition |
| Q38065254 | Animal models of toxicology testing: the role of pigs |
| Q39461122 | Asiatic acid attenuates pre-neoplastic lesions, oxidative stress, biotransforming enzymes and histopathological alterations in 1,2-dimethylhydrazine-induced experimental rat colon carcinogenesis |
| Q48023226 | Assessment of the pulmonary CYP1A1 metabolism of mavoglurant (AFQ056) in rat. |
| Q48032010 | Attenuation of experimental autoimmune neuritis with locally administered lovastatin-encapsulating poly(lactic-co-glycolic) acid nanoparticles |
| Q42970314 | Benzylmorpholine analogs as selective inhibitors of lung cytochrome P450 2A13 for the chemoprevention of lung cancer in tobacco users |
| Q35482371 | Bimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals |
| Q34134358 | Bimodal targeting of microsomal cytochrome P450s to mitochondria: implications in drug metabolism and toxicity |
| Q34363058 | Bioavailability and risk assessment of orally ingested polycyclic aromatic hydrocarbons |
| Q35858693 | Bioinformatics Analysis of the Effects of Tobacco Smoke on Gene Expression |
| Q54336579 | Biotransformation enzymes and lung cell response to 2-hydroxyethyl-methacrylate. |
| Q48030737 | Biotransformation kinetics and sorption of cocaine and its metabolites and the factors influencing their estimation in wastewater |
| Q38357424 | Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer |
| Q38914395 | CYP1A1 I462V polymorphism is associated with reduced genotoxicity in yeast despite positive association with increased cancer risk. |
| Q57813096 | CYP1A1 and 1B1-mediated metabolic pathways of dolutegravir, an HIV integrase inhibitor |
| Q34471338 | CYP2A13 genetic polymorphism in French Caucasian, Gabonese and Tunisian populations |
| Q45766133 | CYP2A6 deletion polymorphism is associated with decreased susceptibility of lung cancer in Asian smokers: a meta-analysis |
| Q37329175 | CYP2A6 polymorphisms and risk for tobacco-related cancers. |
| Q34824471 | CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme |
| Q36432432 | CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor α in Human Liver |
| Q51709663 | CYP2J2 - regulation, function and polymorphism. |
| Q38923338 | CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of β-catenin signaling |
| Q36657755 | CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma |
| Q46007990 | Capsaicin alleviates the imbalance in xenobiotic metabolizing enzymes and tumor markers during experimental lung tumorigenesis. |
| Q28201838 | Catalog of 680 variations among eight cytochrome P450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population |
| Q37643164 | Cell-specific Expression of CYP2A5 in the Mouse Respiratory Tract: Effects of Olfactory Toxicants |
| Q28392962 | Cellular and molecular mechanisms in environmental and occupational inhalation toxicology |
| Q39860920 | Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes |
| Q30917115 | Characterization of Pulmonary CYP4B2, Specific Catalyst of Methyl Oxidation of 3-Methylindole |
| Q39240054 | Characterization of an epoxide-derived metabolite of dictamnine using high-performance liquid chromatography with hybrid linear trap quadrupole orbitrap mass spectrometry |
| Q34178969 | Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif |
| Q24607638 | Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq |
| Q35695041 | Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures during colon cancer initiation and progression in the rat. |
| Q35925302 | Chiral polychlorinated biphenyls: absorption, metabolism and excretion--a review |
| Q91816169 | Circulating Extracellular Vesicles Containing Xenobiotic Metabolizing CYP Enzymes and Their Potential Roles in Extrahepatic Cells Via Cell-Cell Interactions |
| Q52925491 | Combined therapeutic efficacy of carvacrol and X-radiation against 1,2-dimethyl hydrazine-induced experimental rat colon carcinogenesis. |
| Q36553701 | Concepts in molecular dermatotoxicology |
| Q52101444 | Conditional knockout of the mouse NADPH-cytochrome p450 reductase gene. |
| Q42486887 | Coordinate regulation of cytochrome P450 1a1 expression in mouse liver by the aryl hydrocarbon receptor and the beta-catenin pathway |
| Q42710037 | Cytochrome P450 2A13 is an efficient enzyme in metabolic activation of aflatoxin G1 in human bronchial epithelial cells |
| Q34358307 | Cytochrome P450 2J2: distribution, function, regulation, genetic polymorphisms and clinical significance |
| Q50485616 | Cytochrome P450 2W1 (CYP2W1) - ready for use as the biomarker and drug target for cancer? |
| Q46076879 | Cytochrome P450 and Non-Cytochrome P450 Oxidative Metabolism: Contributions to the Pharmacokinetics, Safety, and Efficacy of Xenobiotics |
| Q36572566 | Cytochrome P450 interactions in human cancers: new aspects considering CYP1B1. |
| Q34099083 | Cytochrome P450 levels are altered in patients with esophageal squamous-cell carcinoma |
| Q28564167 | Cytochrome P450 oxidoreductase participates in nitric oxide consumption by rat brain |
| Q37954366 | Cytochrome P450 polymorphisms and drug-induced interstitial lung disease |
| Q36960539 | Cytochrome P450 reaction-phenotyping: an industrial perspective |
| Q44433892 | Cytochrome P450-isoenzyme 1A1 in susceptibility to tobacco-related lung cancer |
| Q36493140 | Cytochrome P450-mediated metabolism and DNA binding of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline and its carcinogenic isomer 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in mice |
| Q42011544 | Cytochrome P450s and cytochrome P450 reductase in the olfactory organ of the cotton leafworm Spodoptera littoralis |
| Q36006519 | Cytochrome p450 enzymes and cardiovascular disease |
| Q37550663 | Cytochrome p450 mRNA expression in the rodent brain: species-, sex-, and region-dependent differences |
| Q24816161 | Decreased expression of cytochrome P450 protein in non-malignant colonic tissue of patients with colonic adenoma |
| Q48247052 | Development of cocaine-induced interstitial lung damage in two CYP2C and VKORC1 variant allele carriers |
| Q37601039 | Dietary flavonoids modulate CYP2C to improve drug oral bioavailability and their qualitative/quantitative structure-activity relationship |
| Q93115203 | Dietary restriction induces posttranscriptional regulation of longevity genes |
| Q40072362 | Dietary supplementation with vitamin D stimulates intestinal epithelial cell turnover after massive small bowel resection in rats |
| Q31155554 | Differential expression of cytochrome P450 enzymes in normal and tumor tissues from childhood rhabdomyosarcoma |
| Q53189497 | Differential gene expression of CYP3A isoforms in equine liver and intestines. |
| Q24811694 | Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa |
| Q38683483 | Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction |
| Q39189868 | Do We Need to Study Metabolism and Distribution in the Eye: Why, When, and Are We There Yet? |
| Q36061821 | Drug bioactivation, covalent binding to target proteins and toxicity relevance |
| Q37550548 | Drug metabolism and pharmacokinetics |
| Q45949148 | Drug-drug interaction and doping, part 1: an in vitro study on the effect of non-prohibited drugs on the phase I metabolic profile of toremifene. |
| Q37188039 | Dual mechanisms of CYP3A protein regulation by proinflammatory cytokine stimulation in primary hepatocyte cultures. |
| Q46861134 | Effect of Ginkgo biloba extract on oxidative metabolism of valproic acid in hepatic microsomes from donors with the CYP2C9*1/*1 genotype |
| Q41456158 | Effect of Short-Term Fasting on Systemic Cytochrome P450-Mediated Drug Metabolism in Healthy Subjects: A Randomized, Controlled, Crossover Study Using a Cocktail Approach |
| Q51296585 | Effect of grapefruit juice and food on the pharmacokinetics of pirfenidone in healthy Chinese volunteers: a diet-drug interaction study. |
| Q44160942 | Effect of mosquito mats (pyrethroid-based) vapor inhalation on rat brain cytochrome P450s |
| Q36874272 | Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice |
| Q57888889 | Effects of Hypericum perforatum hydroalcoholic extract, hypericin, and hyperforin on cytotoxicity and CYP3A4 mRNA expression in hepatic cell lines: a comparative study |
| Q39062803 | Effects of long-term ethanol consumption and Aldh1b1 depletion on intestinal tumourigenesis in mice |
| Q35000765 | Efflux transporters- and cytochrome P-450-mediated interactions between drugs of abuse and antiretrovirals |
| Q35190683 | Elucidating Organ-Specific Metabolic Toxicity Chemistry from Electrochemiluminescent Enzyme/DNA Arrays and Bioreactor Bead-LC-MS/MS. |
| Q64096564 | Esophageal cancer genetics in South Africa |
| Q37496632 | Estrogen receptor-dependent regulation of CYP2B6 in human breast cancer cells |
| Q51928851 | Evaluation of 227 drugs for in vitro inhibition of cytochrome P450 2B6. |
| Q45093840 | Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes via in vivo and in vitro oxidation of midazolam and triazolam |
| Q53568534 | Exposure reconstruction for reducing uncertainty in risk assessment: example using MTBE biomarkers and a simple pharmacokinetic model. |
| Q36878107 | Expression of cytochrome P450 2A13 in human non-small cell lung cancer and its clinical significance |
| Q55031591 | Expression of cytochrome P450 mRNAs in Type II alveolar cells from subjects with chronic obstructive pulmonary disease. |
| Q35173305 | Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers |
| Q57258718 | Extrahepatic Drug-Metabolizing Enzymes and Their Significance |
| Q55281935 | Extrahepatic cytochrome P450s play an insignificant role in triptolide-induced toxicity. |
| Q33837831 | Formation of covalently bound protein adducts from the cytotoxicant naphthalene in nasal epithelium: species comparisons |
| Q24299330 | From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey |
| Q37810200 | From known knowns to known unknowns: predicting in vivo drug metabolites |
| Q34318422 | Gene and protein expression and cellular localisation of cytochrome P450 enzymes of the 1A, 2A, 2C, 2D and 2E subfamilies in equine intestine and liver |
| Q42930859 | Gene expression analysis of membrane transporters and drug-metabolizing enzymes in the lung of healthy and COPD subjects |
| Q37145892 | Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa |
| Q38556530 | Gene-environment interactions in esophageal cancer |
| Q35996452 | Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse model |
| Q33942976 | Generation and characterization of a novel CYP2A13--transgenic mouse model |
| Q36497642 | Generation and characterization of a novel Cyp2a(4/5)bgs-null mouse model |
| Q33289676 | Genetic variability in CYP3A4 and CYP3A5 in primary liver, gastric and colorectal cancer patients |
| Q39965794 | Genetic variation of genes for xenobiotic-metabolizing enzymes and risk of bronchial asthma: the importance of gene-gene and gene-environment interactions for disease susceptibility |
| Q43426007 | Genotoxic bioactivation of constituents of a diesel exhaust particle extract by the human lung |
| Q38429245 | Genotyping of CYP3A5 polymorphisms among Bulgarian patients with sporadic colorectal cancer and controls |
| Q93016091 | Hepatic and intestinal biotransformation gene expression and drug disposition in a dextran sulfate sodium-induced colitis mouse model |
| Q34927091 | Hepatic metabolism affects the atropselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice |
| Q37559609 | Hormonal regulation of CYP1A expression |
| Q90440705 | Human CYP2D6 Is Functional in Brain In Vivo: Evidence from Humanized CYP2D6 Transgenic Mice |
| Q30502781 | Humanized mice with ectopic artificial liver tissues. |
| Q38559382 | Hybrid volatolomics and disease detection |
| Q37781056 | Hypothesis-based weight of evidence: a tool for evaluating and communicating uncertainties and inconsistencies in the large body of evidence in proposing a carcinogenic mode of action--naphthalene as an example |
| Q36518971 | Hypothesis-based weight-of-evidence evaluation and risk assessment for naphthalene carcinogenesis |
| Q34434931 | Identification of cytochrome P450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): insights from a novel Cyp2abfgs-null mouse |
| Q42360559 | Identification of non-reported bupropion metabolites in human plasma |
| Q36283239 | Identification of significant pathways in gastric cancer based on protein-protein interaction networks and cluster analysis |
| Q35835738 | Identification of structural alerts for liver and kidney toxicity using repeated dose toxicity data |
| Q24313179 | Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone |
| Q37724295 | In vitro analysis of factors influencing CYP1A2 expression as potential determinants of interindividual variation |
| Q46709627 | In vitro inhibition of CYP3A4 metabolism and P-glycoprotein-mediated transport by trade herbal products |
| Q37134511 | Increased CYP4B1 mRNA is associated with the inhibition of dextran sulfate sodium-induced colitis by caffeic acid in mice |
| Q33495694 | Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke |
| Q37524932 | Influence of dietary fat type on benzo(a)pyrene [B(a)P] biotransformation in a B(a)P-induced mouse model of colon cancer |
| Q42129498 | Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes |
| Q46104847 | Inhibition of 17β-estradiol activation by CYP1A1: Genotype- and regioselective inhibition by St. John's Wort and several natural polyphenols |
| Q44942366 | Inhibition of rat respiratory-tract cytochrome P-450 activity after acute low-level m-xylene inhalation: role in 1-nitronaphthalene toxicity |
| Q44483426 | Inhibition of small-conductance Cl- channels by the interleukin-1beta-stimulated production of superoxide in rabbit gastric parietal cells |
| Q27304925 | Integrative approach to analyze biodiversity and anti-inflammatory bioactivity of Wedelia medicinal plants |
| Q37106018 | Intestinal cytochromes P450 regulating the intestinal microbiota and its probiotic profile |
| Q35071729 | Keratinocyte growth factor protects against Clara cell injury induced by naphthalene |
| Q45234608 | Kinetic analysis of oxidation of coumarins by human cytochrome P450 2A6. |
| Q35130044 | Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B(1) in rats |
| Q44792952 | Lansoprazole-tacrolimus interaction in Japanese transplant recipient with CYP2C19 polymorphism |
| Q57889260 | Lebensmittelchemie 2010 |
| Q46472643 | Localization of cytochrome P450 CYP2S1 expression in human tissues by in situ hybridization and immunohistochemistry |
| Q36508577 | Mechanism of chloroform-induced renal toxicity: non-involvement of hepatic cytochrome P450-dependent metabolism |
| Q33872242 | Mechanisms of differential expression of the CYP2A13 7520C and 7520G alleles in human lung: allelic expression analysis for CYP2A13 heterogeneous nuclear RNA, and evidence for the involvement of multiple cis-regulatory single nucleotide polymorphism |
| Q61799495 | Metabolic Activation and Carcinogenesis of Tobacco-Specific Nitrosamine N'-Nitrosonornicotine (NNN): A Density Function Theory and Molecular Docking Study |
| Q41889718 | Metabolic and Pharmacokinetic Differentiation of STX209 and Racemic Baclofen in Humans |
| Q28391158 | Metabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic amines |
| Q33840727 | Mice deficient in intestinal epithelium cytochrome P450 reductase are prone to acute toxin-induced mucosal damage. |
| Q58744465 | Microvillous cells in the olfactory epithelium express elements of the solitary chemosensory cell transduction signaling cascade |
| Q44261825 | Mitigating role of baicalein on lysosomal enzymes and xenobiotic metabolizing enzyme status during lung carcinogenesis of Swiss albino mice induced by benzo(a)pyrene |
| Q53087003 | Modulating effect of d-carvone on 1,2-dimethylhydrazine-induced pre-neoplastic lesions, oxidative stress and biotransforming enzymes, in an experimental model of rat colon carcinogenesis. |
| Q47881274 | Modulating nasal mucosal permeation using metabolic saturation and enzyme inhibition techniques |
| Q34462494 | Modulation of N-nitrosomethylbenzylamine metabolism by black raspberries in the esophagus and liver of Fischer 344 rats |
| Q53067235 | Modulatory effect of troxerutin on biotransforming enzymes and preneoplasic lesions induced by 1,2-dimethylhydrazine in rat colon carcinogenesis. |
| Q44995235 | Molecular modelling of CYP2A enzymes: application to metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). |
| Q28592705 | Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) |
| Q36292830 | Multidrug resistance (MDR1) gene in inflammatory bowel disease: a key player? |
| Q31052044 | NGS meta data analysis for identification of SNP and INDEL patterns in human airway transcriptome: A preliminary indicator for lung cancer |
| Q33647378 | Naphthalene metabolism in relation to target tissue anatomy, physiology, cytotoxicity and tumorigenic mechanism of action |
| Q38882614 | Neurotoxicity in the Post-HAART Era: Caution for the Antiretroviral Therapeutics |
| Q92088494 | New insights into host adaptation to swine respiratory disease revealed by genetic differentiation and RNA sequencing analyses |
| Q37028008 | Nicotine Increases Codeine Analgesia Through the Induction of Brain CYP2D and Central Activation of Codeine to Morphine. |
| Q35099123 | Nicotine exposure and metabolizer phenotypes from analysis of urinary nicotine and its 15 metabolites by LC-MS. |
| Q38706678 | Nitric oxide-regulated proteolysis of human CYP2B6 via the ubiquitin-proteasome system |
| Q34912607 | Nutrition and the prevention and treatment of cancer: association of cytochrome P450 CYP1B1 with the role of fruit and fruit extracts |
| Q34651516 | Odorant metabolism catalyzed by olfactory mucosal enzymes influences peripheral olfactory responses in rats |
| Q36728950 | Olfactory uptake of manganese requires DMT1 and is enhanced by anemia |
| Q90354935 | Organ-Specific Screening for Protein Damage Using Magnetic Bead Bioreactors and LC-MS/MS |
| Q38111712 | Oxidants and redox signaling in acute lung injury |
| Q88640110 | Pathways of Metabolite-Related Damage to a Synthetic p53 Gene Exon 7 Oligonucleotide Using Magnetic Enzyme Bioreactor Beads and LC-MS/MS Sequencing |
| Q51112914 | Personalized oxycodone dosing: using pharmacogenetic testing and clinical pharmacokinetics to reduce toxicity risk and increase effectiveness. |
| Q90623180 | Pesticide toxicity: a mechanistic approach |
| Q37182212 | PhRMA white paper on ADME pharmacogenomics. |
| Q27012807 | PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6 |
| Q38815352 | Pharmacokinetic Drug Interactions with Tobacco, Cannabinoids and Smoking Cessation Products |
| Q36110576 | Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP. |
| Q51905139 | Physiologically based pharmacokinetic modelling: a sub-compartmentalized model of tissue distribution. |
| Q45030843 | Pigs in Toxicology: Breed Differences in Metabolism and Background Findings. |
| Q36820603 | Pilot study of CYP2B6 genetic variation to explore the contribution of nitrosamine activation to lung carcinogenesis. |
| Q46149439 | Plasma caffeic acid is associated with statistical clustering of the anticolitic efficacy of caffeic acid in dextran sulfate sodium-treated mice |
| Q35637318 | Polycyclic aromatic hydrocarbons and digestive tract cancers: a perspective |
| Q36885659 | Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance |
| Q33290134 | Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk |
| Q34311334 | Potent Mutagenicity of 3-Methylindole Requires Pulmonary Cytochrome P450-Mediated Bioactivation: A Comparison to the Prototype Cigarette Smoke Mutagens B(a)P and NNK |
| Q33437736 | Prediction of hepatic clearance in human from in vitro data for successful drug development |
| Q92924537 | Predominant Mycotoxins, Pathogenesis, Control Measures, and Detection Methods in Fermented Pastes |
| Q41905925 | Preferential expression of cytochrome CYP CYP2R1 but not CYP1B1 in human cord blood hematopoietic stem and progenitor cells |
| Q46099886 | Preparation of Specific Compartments of the Lungs for Pathologic and Biochemical Analysis of Toxicologic Responses |
| Q38741017 | Prognosis genes in gastric adenocarcinoma identified by cross talk genes in disease‑related pathways |
| Q38244067 | Proteomics in mechanistic toxicology: history, concepts, achievements, caveats, and potential |
| Q44645569 | Pulmonary cytochrome P450 enzymes belonging to the CYP4B subfamily from an Australian marsupial, the tammar wallaby (Macropus eugenii) |
| Q37587216 | QSAR of cytochrome inhibitors |
| Q28540182 | Qualitative de novo analysis of full length cDNA and quantitative analysis of gene expression for common marmoset (Callithrix jacchus) transcriptomes using parallel long-read technology and short-read sequencing |
| Q30525178 | RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes |
| Q30361702 | Rapid birth-death evolution specific to xenobiotic cytochrome P450 genes in vertebrates |
| Q26765805 | Redox Control of Multidrug Resistance and Its Possible Modulation by Antioxidants |
| Q42112553 | Reduction of aromatic and heterocyclic aromatic N-hydroxylamines by human cytochrome P450 2S1. |
| Q43115159 | Regulatory mechanisms to control tissue alpha-tocopherol. |
| Q47741693 | Respiratory sensitization: toxicological point of view on the available assays |
| Q42562000 | Response to letter by Dr. Marc Hershenson (exposure of airway smooth muscle cells to cigarette smoke extract). |
| Q36695365 | Resveratrol inhibits benzo[a]pyrene-DNA adduct formation in human bronchial epithelial cells |
| Q34667734 | Retracted: Association of CYP2A6*4 with Susceptibility of Lung Cancer: A Meta-Analysis |
| Q37412014 | Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model |
| Q88654500 | Role of Sequence Variations in AhR Gene Towards Modulating Smoking Induced Lung Cancer Susceptibility in North Indian Population: A Multiple Interaction Analysis |
| Q36316872 | Role of efflux pumps and metabolising enzymes in drug delivery |
| Q26765518 | Role of endoplasmic reticulum stress in drug-induced toxicity |
| Q34405400 | Role of hepatic and intestinal p450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice |
| Q35002429 | Role of intestinal cytochrome P450 (P450) in modulating the bioavailability of oral lovastatin: insights from studies on the intestinal epithelium-specific P450 reductase knockout mouse |
| Q34169548 | Role of metabolic activation and the TRPA1 receptor in the sensory irritation response to styrene and naphthalene |
| Q36572621 | Role of the aryl hydrocarbon receptor in drug metabolism |
| Q28307748 | Role of the modulation of CYP1A1 expression and activity in chemoprevention |
| Q38582374 | Safety and efficacy of intranasally administered medications in the emergency department and prehospital settings |
| Q47912016 | Salvia fruticosa Modulates mRNA Expressions and Activity Levels of Xenobiotic Metabolizing CYP1A2, CYP2E1, NQO1, GPx, and GST Enzymes in Human Colorectal Adenocarcinoma HT-29 Cells |
| Q36296210 | Selective expression of CYP2A13 in human pancreatic α-islet cells |
| Q28394227 | Sensory irritation as a basis for setting occupational exposure limits |
| Q35589761 | Separation and detection methods for covalent drug-protein adducts |
| Q44208681 | Severe acute nephrotoxicity in a kidney transplant patient despite low tacrolimus levels: a possible interaction between donor and recipient genetic polymorphisms |
| Q90202659 | Similarities and differences in the biotransformation and transcriptomic responses of Caenorhabditis elegans and Haemonchus contortus to five different benzimidazole drugs |
| Q36588312 | Species difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126 |
| Q35165381 | Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compounds |
| Q33651967 | Stereoselective biotransformation of ketamine in equine liver and lung microsomes |
| Q54516740 | Stress is a critical player in CYP3A, CYP2C, and CYP2D regulation: role of adrenergic receptor signaling pathways. |
| Q30396630 | Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR. |
| Q24316102 | Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates |
| Q42176374 | Supramolecular protein assembly supports immobilization of a cytochrome P450 monooxygenase system as water-insoluble gel. |
| Q42933973 | Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smoke exposure in nasal and bronchial tissues |
| Q37731519 | Tamoxifen-DNA adduct formation in monkey and human reproductive organs |
| Q35962274 | Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development |
| Q38072075 | The development of models for the evaluation of pulmonary drug disposition |
| Q40575130 | The human CYP1A1 gene is regulated in a developmental and tissue-specific fashion in transgenic mice |
| Q34169785 | The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans |
| Q45556999 | The influence of smoking on bone loss and response to nasal estradiol. |
| Q35828032 | The unique regulation of brain cytochrome P450 2 (CYP2) family enzymes by drugs and genetics. |
| Q54238102 | Tissue Distribution and Gender-Specific Protein Expression of Cytochrome P450 in five Mouse Genotypes with a Background of FVB. |
| Q47695475 | Tissue distribution of CYP3A29 mRNA expression in Bama miniature pig by quantitative reverse transcriptase-polymerase chain reaction (RT-PCR). |
| Q92309713 | Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung |
| Q22305492 | Toxic hepatitis in occupational exposure to solvents |
| Q37204684 | Toxicity and metabolism of methylnaphthalenes: comparison with naphthalene and 1-nitronaphthalene. |
| Q40620243 | Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague-Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology |
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