Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability

scientific article published on 15 July 2019

Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP4.1406
P932PMC publication ID6824060
P698PubMed publication ID31701068

P50authorSanjeev GumberQ40048306
Daniel M ChopykQ89492252
Mehul S. SutharQ90167763
Mark J CzajaQ90707713
P2093author name stringArash Grakoui
Jing Wen
Matthew G Zimmerman
Johnasha D Stuart
Manoj Thapa
P2860cites workHydrogen sulfide protects against acetaminophen-induced acute liver injury by inhibiting apoptosis via the JNK/MAPK signaling pathwayQ91802535
Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosaQ24811694
Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tractsQ28217340
Apoptosis: a review of programmed cell deathQ28305845
Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or NecrosisQ33755165
Identifying the stem cell of the intestinal crypt: strategies and pitfallsQ34304069
Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatmentQ34551121
Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis.Q34789354
HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicityQ35141090
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's DiseaseQ36212145
Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeabilityQ37051510
Character and temporal evolution of apoptosis in acetaminophen-induced acute liver failure*.Q37612383
Acetaminophen-related hepatotoxicityQ38149899
Disrupted barrier function through epithelial cell apoptosisQ40216846
Further studies on the response of intestinal crypt cells of different hierarchical status to eighteen different cytotoxic agentsQ41158641
Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epitheliumQ41285833
Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in miceQ42556951
Outcomes of liver transplantation for paracetamol (acetaminophen)-induced hepatic failureQ43269343
Lgr5+ stem cells are indispensable for radiation-induced intestinal regenerationQ43548445
Acetaminophen changes intestinal epithelial cell membrane properties, subsequently affecting absorption processesQ43605000
Alterations in cytokine/chemokine expression during organ-to-organ communication established via acetaminophen-induced toxicityQ44651552
The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicityQ46835446
Dysregulation of junctional adhesion molecule-A contributes to ethanol-induced barrier disruption in intestinal epithelial cell monolayers.Q47134866
Acute Liver FailureQ56069625
Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic ShockQ57099957
Cryopreserved human intestinal mucosal epithelium: a novel in vitro experimental system for the evaluation of enteric drug metabolism, P450 induction, and enterotoxicityQ57099979
Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicityQ57461348
Acute Brain Damage Induced by Acetaminophen in Mice: Effect of Diphenyl Diselenide on Oxidative Stress and Mitochondrial DysfunctionQ59273475
Inhibition of tumour necrosis factor alpha does not prevent experimental paracetamol-induced hepatic necrosisQ73504535
Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsisQ77855901
Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in miceQ88014266
The gut-liver axis and the intersection with the microbiomeQ88634168
The role of apoptosis in acetaminophen hepatotoxicityQ89151907
P433issue11
P921main subjectparacetamolQ57055
P304page(s)1435-1449
P577publication date2019-07-15
P1433published inHepatology CommunicationsQ50817751
P1476titleAcetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability
P478volume3