| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1038901885 |
| P356 | DOI | 10.1186/1471-230X-14-66 |
| P932 | PMC publication ID | 3985724 |
| P698 | PubMed publication ID | 24708589 |
| P2093 | author name string | Jyrki Tenhunen | |
| Xiaoping Zou | |||
| Runkuan Yang | |||
| Shengtao Zhu | |||
| Henri Kajander | |||
| Marja-Leena Koskinen | |||
| Tor Inge Tonnessen | |||
| P2860 | cites work | A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release | Q24321082 |
| Release of chromatin protein HMGB1 by necrotic cells triggers inflammation | Q28131815 | ||
| Selective protein arylation and acetaminophen-induced hepatotoxicity | Q30427535 | ||
| Liver regeneration | Q33870218 | ||
| Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity | Q34074958 | ||
| Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation | Q34156078 | ||
| High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity | Q34262481 | ||
| Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure | Q34331677 | ||
| Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice. | Q52522262 | ||
| Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice. | Q53538229 | ||
| Leaky gut hypothesis: a historical perspective | Q68759507 | ||
| Role of macrophages in acetaminophen (paracetamol)-induced hepatotoxicity | Q71681485 | ||
| Mild hypothermia attenuates liver injury and improves survival in mice with acetaminophen toxicity | Q79621336 | ||
| The cytokine activity of HMGB1. | Q34398253 | ||
| Tissue repair: an important determinant of final outcome of toxicant-induced injury | Q34408161 | ||
| Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock | Q35052743 | ||
| Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor | Q35997495 | ||
| Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose | Q36093484 | ||
| Intracellular signaling mechanisms of acetaminophen-induced liver cell death | Q36263962 | ||
| The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion | Q36403403 | ||
| HMGB1 as a potential therapeutic target | Q36767904 | ||
| High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity | Q36990574 | ||
| The evolving story of macrophages in acute liver failure | Q38028255 | ||
| HMGB1 modulates inflammatory responses in LPS-activated macrophages | Q40128453 | ||
| Hepatocyte and immune system: acute phase reaction as a contribution to early defence mechanisms | Q40394411 | ||
| Hepatic cell division and tissue repair: a key to survival after liver injury | Q41105352 | ||
| Macrophages and inflammatory mediators in chemical toxicity: a battle of forces | Q42134547 | ||
| Mice overexpressing the gene for heparin-binding epidermal growth factor-like growth factor (HB-EGF) have increased resistance to hemorrhagic shock and resuscitation | Q42573638 | ||
| Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock | Q44028476 | ||
| HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice | Q44116679 | ||
| Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease | Q44410276 | ||
| Bacterial translocation in acute liver injury induced by D-galactosamine | Q44632263 | ||
| Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen-induced toxicity in mice | Q44673571 | ||
| Ethyl pyruvate ameliorates acute alcohol-induced liver injury and inflammation in mice | Q44675014 | ||
| Lipopolysaccharide-binding protein modulates acetaminophen-induced liver injury in mice | Q44934325 | ||
| Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis | Q44969138 | ||
| Bile high-mobility group box 1 contributes to gut barrier dysfunction in experimental endotoxemia. | Q45983944 | ||
| P275 | copyright license | Creative Commons Attribution 2.0 Generic | Q19125117 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | paracetamol | Q57055 |
| hepatotoxicity | Q1349821 | ||
| P304 | page(s) | 66 | |
| P577 | publication date | 2014-04-05 | |
| P1433 | published in | BMC Gastroenterology | Q15759922 |
| P1476 | title | HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity | |
| P478 | volume | 14 |
| Q41593902 | A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice |
| Q91178769 | Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability |
| Q51702513 | Chemokine (C-C motif) receptor 2-positive monocytes aggravate the early phase of acetaminophen-induced acute liver injury. |
| Q95362919 | Diclofenac Sodium Treatment Ameliorates Extrapancreatic Organ Injuries in a Murine Model of Acute Pancreatitis Induced by Caerulein |
| Q35406168 | Elevated HMGB1-related interleukin-6 is associated with dynamic responses of monocytes in patients with active pulmonary tuberculosis |
| Q28068263 | Ethyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuries |
| Q39426851 | HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure |
| Q39186586 | HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis. |
| Q35045701 | High-mobility group box 1 protein and its role in severe acute pancreatitis |
| Q38311148 | Immune mechanisms in acetaminophen-induced acute liver failure |
| Q90695387 | Intestinal Epithelial Chemokine (C-C Motif) Ligand 7 Overexpression Enhances Acetaminophen-Induced Hepatotoxicity in Mice |
| Q33848167 | Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology |
| Q42256796 | Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity. |
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