| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.3109/03602539709037573 |
| P698 | PubMed publication ID | 9187511 |
| P2093 | author name string | S D Cohen | |
| E A Khairallah | |||
| P2860 | cites work | N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen | Q28268181 |
| A metabolite of acetaminophen covalently binds to the 56 kDa selenium binding protein | Q28319102 | ||
| Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: correlation of nuclear Ca2+ accumulation and early DNA fragmentation with cell death | Q28334002 | ||
| DNA sequencing of a mouse liver protein that binds selenium: implications for selenium's mechanism of action in cancer prevention | Q28511425 | ||
| Macromolecular domains within the cell nucleus | Q29618685 | ||
| Alkylation of the liver plasma membrane and inhibition of the Ca2+ ATPase by acetaminophen | Q30403284 | ||
| Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: Analysis of instances of therapeutic misadventure | Q34303815 | ||
| Different patterns of regulation of the genes encoding the closely related 56 kDa selenium- and acetaminophen-binding proteins in normal tissues and during carcinogenesis | Q34361964 | ||
| Purification, antibody production, and partial amino acid sequence of the 58-kDa acetaminophen-binding liver proteins | Q34366778 | ||
| Metabolic zonation of the liver: regulation and implications for liver function | Q35417325 | ||
| Calcium-Mediated Mechanisms in Chemically Induced Cell Death | Q36213544 | ||
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| The relationship between cellular ion deregulation and acute and chronic toxicity | Q38602125 | ||
| An Evaluation of the Role of Calcium in Cell Injury | Q39373633 | ||
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| Mechanisms of Acetaminophen Toxicity: Immunochemical Detection of Drug-Protein Adducts | Q40463574 | ||
| Specific targets of covalent drug-protein interactions in hepatocytes and their toxicological significance in drug-induced liver injury | Q40817414 | ||
| Cytotoxic effects of N-acetyl-p-benzoquinone imine, a common arylating intermediate of paracetamol and N-hydroxyparacetamol | Q41593798 | ||
| Immunochemical analysis of acetaminophen covalent binding to proteins. Partial characterization of the major acetaminophen-binding liver proteins | Q43525945 | ||
| Effects of ethanol and inhibitors on the binding and metabolism of acetaminophen and N-acetyl-p-benzoquinone imine by hepatic microsomes from control and ethanol-treated rats | Q43587661 | ||
| Selective alterations in the patterns of newly synthesized proteins by acetaminophen and its dimethylated analogues in primary cultures of mouse hepatocytes | Q43742165 | ||
| Paracetamol-induced hepatic necrosis in the mouse-relationship between covalent binding, hepatic glutathione depletion and the protective effect of alpha-mercaptopropionylglycine | Q43861375 | ||
| Acetaminophen hepatotoxicity: correspondence of selective protein arylation in human and mouse liver in vitro, in culture, and in vivo | Q44689259 | ||
| Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice | Q44944222 | ||
| Genes encoding the acetaminophen and selenium binding proteins map to mouse chromosome 3. | Q48057159 | ||
| Identification of the mouse liver 44-kDa acetaminophen-binding protein as a subunit of glutamine synthetase | Q48070308 | ||
| Reversal of acetaminophen toxicity in isolated hamster hepatocytes by dithiothreitol. | Q50910005 | ||
| Intracellular calcium disruption as a secondary event in acetaminophen-induced hepatotoxicity. | Q52518013 | ||
| Species differences in hepatic glutathione depletion, covalent binding and hepatic necrosis after acetaminophen. | Q53715160 | ||
| Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters. | Q53995063 | ||
| Ultrastructural changes during acute acetaminophen-induced hepatotoxicity in the mouse: a time and dose study. | Q54106117 | ||
| Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen. | Q54306619 | ||
| Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. | Q54662525 | ||
| P433 | issue | 1-2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hepatotoxicity | Q1349821 |
| P304 | page(s) | 59-77 | |
| P577 | publication date | 1997-02-01 | |
| P1433 | published in | Drug Metabolism Reviews | Q5308857 |
| P1476 | title | Selective protein arylation and acetaminophen-induced hepatotoxicity | |
| P478 | volume | 29 |
| Q34027600 | Acetaminophen hepatotoxicity: An update |
| Q61640562 | Acetaminophen-induced -nitrosylation and -sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids |
| Q35956222 | Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition |
| Q37512777 | Acylcarnitine profiles in acetaminophen toxicity in the mouse: comparison to toxicity, metabolism and hepatocyte regeneration |
| Q35101500 | Age-related changes in the hepatic pharmacology and toxicology of paracetamol |
| Q34560275 | Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity |
| Q44651552 | Alterations in cytokine/chemokine expression during organ-to-organ communication established via acetaminophen-induced toxicity |
| Q36382247 | Apoptosis and necrosis in the liver: a tale of two deaths? |
| Q43215803 | Attenuation of Acetaminophen-Induced Hepatotoxicity In Vivo and In Vitro by a 43-kD Protein Isolated from the Herb Cajanus indicus L. |
| Q59276899 | Attenuation of Kupffer Cell Function in Acute on Chronic Liver Injury Enhanced Engraftment of Transplanted Hepatocytes |
| Q28486047 | CREBH determines the severity of sulpyrine-induced fatal shock |
| Q34164559 | Challenges and limitations of gene expression profiling in mechanistic and predictive toxicology |
| Q43559068 | Changes in susceptibility to acetaminophen-induced liver injury by the organic anion indocyanine green |
| Q36581963 | Classical and alternative activation of rat hepatic sinusoidal endothelial cells by inflammatory stimuli |
| Q36061821 | Drug bioactivation, covalent binding to target proteins and toxicity relevance |
| Q37427278 | Effects of acetaminophen on mitochondrial complex I activity in the rat liver and kidney: a PET study with 18F-BCPP-BF. |
| Q36221425 | Enhanced Production of Adenosine Triphosphate by Pharmacological Activation of Adenosine Monophosphate-Activated Protein Kinase Ameliorates Acetaminophen-Induced Liver Injury |
| Q42164557 | Extensive protein carbonylation precedes acrolein-mediated cell death in mouse hepatocytes |
| Q38240924 | Extracorporeal treatment for acetaminophen poisoning: recommendations from the EXTRIP workgroup |
| Q36331567 | Functional role of monocytes and macrophages for the inflammatory response in acute liver injury |
| Q36642297 | Glycocapture-assisted global quantitative proteomics (gagQP) reveals multiorgan responses in serum toxicoproteome |
| Q35141090 | HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity |
| Q89768096 | Hepatoprotective Effect of Citrus aurantium L. Against APAP-induced Liver Injury by Regulating Liver Lipid Metabolism and Apoptosis |
| Q43775840 | Hepatoprotective effects of Platycodon grandiflorum on acetaminophen-induced liver damage in mice |
| Q93942848 | Hepatotoxicity of acetaminophen and N-acetyl-p-benzoquinone imine and enhancement by fructose |
| Q34262481 | High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity |
| Q35760821 | IRE1α activation protects mice against acetaminophen-induced hepatotoxicity |
| Q34078203 | JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo. |
| Q47102849 | Lysophosphatidic acid protects against acetaminophen-induced acute liver injury |
| Q34071991 | Lysosomal iron mobilization and induction of the mitochondrial permeability transition in acetaminophen-induced toxicity to mouse hepatocytes. |
| Q37463698 | Mechanism of protection by metallothionein against acetaminophen hepatotoxicity |
| Q24629891 | Mechanisms of acetaminophen-induced liver necrosis |
| Q38212434 | Mechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patients |
| Q41948906 | NQO2 is a reactive oxygen species generating off-target for acetaminophen. |
| Q35195519 | Nrf2-mediated liver protection by sauchinone, an antioxidant lignan, from acetaminophen toxicity through the PKCδ-GSK3β pathway |
| Q33781271 | Pharmacogenetics of cytochromes P450. |
| Q77933557 | Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species |
| Q31860421 | Prevention of acetaminophen-induced liver toxicity by 2(R,S)-n-propylthiazolidine-4(R)-carboxylic acid in mice |
| Q37210142 | Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity |
| Q48251701 | Protective effects of tannic acid on pressure overload-induced cardiac hypertrophy and underlying mechanisms in rats. |
| Q30883318 | Protein targets of monocrotaline pyrrole in pulmonary artery endothelial cells |
| Q36804882 | Protein targets of reactive metabolites of thiobenzamide in rat liver in vivo |
| Q34819836 | Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting |
| Q46252513 | Reduced acetaminophen-induced liver injury in mice by genetic disruption of IL-1 receptor antagonist. |
| Q36040842 | Regulation of alternative macrophage activation in the liver following acetaminophen intoxication by stem cell-derived tyrosine kinase |
| Q39790357 | Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice |
| Q84450207 | Renal function and arterial blood pressure alterations after exposure to acetaminophen with a potential role of Nigella sativa oil in adult male rats |
| Q34074958 | Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity |
| Q36923111 | Robust protein nitration contributes to acetaminophen-induced mitochondrial dysfunction and acute liver injury |
| Q37442120 | Role of cytochrome P450 2E1 in protein nitration and ubiquitin-mediated degradation during acetaminophen toxicity |
| Q35564727 | S-adenosyl-l-methionine protection of acetaminophen mediated oxidative stress and identification of hepatic 4-hydroxynonenal protein adducts by mass spectrometry |
| Q33236211 | Selenium-binding protein 2, the major hepatic target for acetaminophen, shows sex differences in protein abundance |
| Q35589761 | Separation and detection methods for covalent drug-protein adducts |
| Q37612627 | TRPM2 channels mediate acetaminophen-induced liver damage |
| Q33760064 | The hepatic stem cell niche: identification by label-retaining cell assay |
| Q42704179 | The protective role of NAD(P)H:quinone oxidoreductase 1 on acetaminophen-induced liver injury is associated with prevention of adenosine triphosphate depletion and improvement of mitochondrial dysfunction |
| Q60932222 | Therapeutic Potential of Plants and Plant Derived Phytochemicals against Acetaminophen-Induced Liver Injury |
| Q34005330 | Xenobiotic-metabolizing enzymes as autoantigens in human autoimmune disorders. An update. |
| Q42965190 | rhIL-1Ra reduces hepatocellular apoptosis in mice with acetaminophen-induced acute liver failure |
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