| scholarly article | Q13442814 |
| P356 | DOI | 10.1111/J.1476-5381.2010.01095.X |
| P953 | full work available at URL | https://doi.org/10.1111/j.1476-5381.2010.01095.x |
| https://europepmc.org/articles/PMC3166693 | ||
| https://europepmc.org/articles/pmc3166693?pdf=render | ||
| https://europepmc.org/articles/PMC3166693?pdf=render | ||
| https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21039417/?tool=EBI | ||
| https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21039417/pdf/?tool=EBI | ||
| P932 | PMC publication ID | 3166693 |
| P698 | PubMed publication ID | 21039417 |
| P5875 | ResearchGate publication ID | 47642739 |
| P2093 | author name string | Sang Hyun Sung | |
| Young Woo Kim | |||
| Sang Geon Kim | |||
| Se Jin Hwang | |||
| Da Hye Ryu | |||
| Hee Yeon Kay | |||
| P2860 | cites work | Acetaminophen-induced hepatotoxicity | Q28185453 |
| An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements | Q28244853 | ||
| Nrf2 is essential for protection against acute pulmonary injury in mice | Q28343659 | ||
| Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous | Q28508176 | ||
| PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress | Q28511471 | ||
| Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice | Q29615438 | ||
| Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers | Q29616503 | ||
| Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription | Q29617066 | ||
| Selective protein arylation and acetaminophen-induced hepatotoxicity | Q30427535 | ||
| High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes | Q31783158 | ||
| Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1. | Q33707120 | ||
| Up-regulation of NAD(P)H quinone oxidoreductase 1 during human liver injury | Q33866612 | ||
| Protein oxidation and aging | Q34243989 | ||
| Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice | Q34640445 | ||
| Inhibition of lipopolysaccharide‐inducible nitric oxide synthase, TNF‐α and COX‐2 expression by sauchinone effects on I‐κBα phosphorylation, C/EBP and AP‐1 activation | Q35045262 | ||
| Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen. | Q35828534 | ||
| Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans | Q37363157 | ||
| Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism | Q38308355 | ||
| Sauchinone, a Lignan from Saururus chinensis, Inhibits Staurosporine-Induced Apoptosis in C6 Rat Glioma Cells | Q38519310 | ||
| Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB. | Q39318861 | ||
| Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2. | Q40301567 | ||
| Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1. | Q40445871 | ||
| Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis | Q43223981 | ||
| Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells | Q43556602 | ||
| Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust | Q43662015 | ||
| Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene | Q43829185 | ||
| Sauchinone, a lignan from Saururus chinensis, suppresses iNOS expression through the inhibition of transactivation activity of RelA of NF-kappaB. | Q44746982 | ||
| Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury. | Q45925809 | ||
| Protective effect of sauchinone by upregulating heme oxygenase-1 via the P38 MAPK and Nrf2/ARE pathways in HepG2 cells. | Q45933050 | ||
| The role of phase II antioxidant enzymes in protecting memory T cells from spontaneous apoptosis in young and old mice | Q46664087 | ||
| Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. | Q46808839 | ||
| Inhibition of osteoclast differentiation and bone resorption by sauchinone. | Q51979767 | ||
| Acetaminophen toxicity. Opposite effects of two forms of glutathione peroxidase. | Q54100952 | ||
| The effect of omeprazole pretreatment on acetaminophen metabolism in rapid and slow metabolizers of S-mephenytoin | Q73562528 | ||
| Hepatoprotective diastereomeric lignans from Saururus chinensis herbs | Q74104284 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | paracetamol | Q57055 |
| P304 | page(s) | 1653-1665 | |
| P577 | publication date | 2011-08-01 | |
| P1433 | published in | British Journal of Pharmacology | Q919631 |
| P1476 | title | Nrf2-mediated liver protection by sauchinone, an antioxidant lignan, from acetaminophen toxicity through the PKCδ-GSK3β pathway | |
| P478 | volume | 163 |
| Q39345969 | A critical review on hepatoprotective effects of bioactive food components. |
| Q46448963 | Antioxidant activities of ginsenoside Rg1 against cisplatin-induced hepatic injury through Nrf2 signaling pathway in mice |
| Q26738964 | Chronic over-nutrition and dysregulation of GSK3 in diseases |
| Q38167610 | Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases. |
| Q39094306 | Naturally Occurring Nrf2 Activators: Potential in Treatment of Liver Injury. |
| Q28396556 | Nrf2 inhibits epithelial-mesenchymal transition by suppressing snail expression during pulmonary fibrosis |
| Q92869440 | Nrf2 signaling attenuates epithelial-to-mesenchymal transition and renal interstitial fibrosis via PI3K/Akt signaling pathways |
| Q43226578 | Nuclear factor (erythroid-derived 2)-like 2, the brake in oxidative stress that nicotinamide adenine dinucleotide phosphate-oxidase-4 needs to protect the heart |
| Q55716716 | Oleanolic acid attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells. |
| Q36476000 | Protection against acetaminophen-induced acute liver failure by omentum adipose tissue derived stem cells through the mediation of Nrf2 and cytochrome P450 expression |
| Q36879950 | Role of the Nrf2-ARE pathway in liver diseases |
| Q47155068 | Sake lees hydrolysate protects against acetaminophen-induced hepatotoxicity via activation of the Nrf2 antioxidant pathway |
| Q37989366 | Target molecules of food phytochemicals: food science bound for the next dimension |
| Q37883102 | Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway. |
| Q26779146 | The Role of Oxidative Stress and Antioxidants in Liver Diseases |
| Q60932222 | Therapeutic Potential of Plants and Plant Derived Phytochemicals against Acetaminophen-Induced Liver Injury |
| Q34678974 | Therapeutic targeting of GSK3β enhances the Nrf2 antioxidant response and confers hepatic cytoprotection in hepatitis C. |
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