| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | William M Lee | |
| P2860 | cites work | Paracetamol pack size restriction: the impact on paracetamol poisoning and the over-the-counter supply of paracetamol, aspirin and ibuprofen | Q23724881 |
| Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and after study | Q28365305 | ||
| Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States | Q34165115 | ||
| Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: Analysis of instances of therapeutic misadventure | Q34303815 | ||
| Acute Liver Failure in the United States | Q34542334 | ||
| Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: an explanation for high acetaminophen dosage in humans without hepatic injury | Q34756497 | ||
| Changing Patterns of Causation and the Use of Transplantation in the United Kingdom | Q35549228 | ||
| Severity of overdose after restriction of paracetamol availability: retrospective study | Q38631431 | ||
| Acetaminophen toxicity in an urban county hospital | Q39454333 | ||
| Acetaminophen hepatotoxicity in alcoholics. A therapeutic misadventure | Q39727500 | ||
| FDA fails to reduce accessibility of paracetamol despite 450 deaths a year | Q42779844 | ||
| Viral and clinical factors associated with the fulminant course of hepatitis A infection | Q44562450 | ||
| Association of acetaminophen hepatotoxicity with fasting and ethanol use. | Q51592407 | ||
| Etiology and outcome for 295 patients with acute liver failure in the United States. | Q52907526 | ||
| A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993) | Q71584382 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | paracetamol | Q57055 |
| liver failure | Q970208 | ||
| P304 | page(s) | 6-9 | |
| P577 | publication date | 2004-07-01 | |
| P1433 | published in | Hepatology | Q15724398 |
| P1476 | title | Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure | |
| P478 | volume | 40 |
| Q43157715 | "Unintentional" acetaminophen overdose on the rise: who is responsible? Dr Robert J Fontana is interviewed by Paul C Adams |
| Q50295997 | A Prominent Role of Interleukin-18 in Acetaminophen-Induced Liver Injury Advocates Its Blockage for Therapy of Hepatic Necroinflammation |
| Q38570734 | A descriptive analysis of aspartate and alanine aminotransferase rise and fall following acetaminophen overdose. |
| Q51310956 | A generalisation of T-optimality for discriminating between competing models with an application to pharmacokinetic studies. |
| Q90627832 | A mitochondrial journey through acetaminophen hepatotoxicity |
| Q47266842 | A survey of adult awareness and use of medicine containing acetaminophen |
| Q47207031 | Acetaminophen Poisoning May Increase Coronary Artery Disease Risk: A Nationwide Cohort Study |
| Q36153444 | Acetaminophen Poisoning and Risk of Acute Pancreatitis: A Population-Based Cohort Study |
| Q35792449 | Acetaminophen and diphenhydramine premedication for allergic and febrile nonhemolytic transfusion reactions: good prophylaxis or bad practice? |
| Q80594536 | Acetaminophen hepatotoxicity |
| Q44967726 | Acetaminophen hepatoxicity: what do we know, what don't we know, and what do we do next? |
| Q42498074 | Acetaminophen increases the risk of arsenic-mediated development of hepatic damage in rats by enhancing redox-signaling mechanism |
| Q34601408 | Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study |
| Q34781465 | Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice |
| Q51795776 | Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice. |
| Q38272082 | Acetaminophen/paracetamol: A history of errors, failures and false decisions |
| Q37324707 | Acquired resistance to acetaminophen hepatotoxicity is associated with induction of multidrug resistance-associated protein 4 (Mrp4) in proliferating hepatocytes. |
| Q36054934 | Acute liver failure: Summary of a workshop |
| Q35565411 | Acute liver failure: a life-threatening disease. |
| Q35597357 | Age and paracetamol self-poisoning |
| Q46591900 | Alpha-lipoic acid treatment of acetaminophen-induced rat liver damage |
| Q90313359 | Alternatively activated macrophages promote resolution of necrosis following acute liver injury |
| Q37009975 | An amino acids mixture improves the hepatotoxicity induced by acetaminophen in mice |
| Q64238149 | An integrated safety analysis of combined acetaminophen and ibuprofen (Maxigesic /Combogesic) in adults |
| Q53689504 | Analgesics in patients with hepatic impairment: pharmacology and clinical implications. |
| Q34562529 | Antidote use in the critically ill poisoned patient |
| Q53205688 | Antioxidant and hepatoprotective activity of vitex honey against paracetamol induced liver damage in mice. |
| Q36382247 | Apoptosis and necrosis in the liver: a tale of two deaths? |
| Q43232351 | Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity |
| Q37316489 | Beta-catenin activation promotes liver regeneration after acetaminophen-induced injury |
| Q46373986 | CXCL16 deficiency attenuates acetaminophen-induced hepatotoxicity through decreasing hepatic oxidative stress and inflammation in mice |
| Q36534046 | Caspase-3/7-mediated Cleavage of β2-spectrin is Required for Acetaminophen-induced Liver Damage |
| Q91785591 | Characteristics and Outcomes of Acetaminophen Overdose and Hepatotoxicity in Thailand |
| Q46409648 | Chemoprotective effects of a protein from the red algae Porphyra yezoensis on acetaminophen-induced liver injury in rats |
| Q35849904 | Chemoprotective effects of a recombinant protein from Pyropia yezoensis and synthetic peptide against acetaminophen-induced Chang liver cell death |
| Q35864836 | Chlorogenic acid prevents acetaminophen-induced liver injury: the involvement of CYP450 metabolic enzymes and some antioxidant signals |
| Q60609564 | Circulating microRNAs as potential markers of human drug-induced liver injury |
| Q39192523 | Combination paracetamol and ibuprofen for pain relief after oral surgery: a dose ranging study |
| Q38954228 | Comparative evaluation of N-acetylcysteine and N-acetylcysteineamide in acetaminophen-induced hepatotoxicity in human hepatoma HepaRG cells |
| Q40376467 | Comparing the Therapeutic Effectiveness of N-acetylcysteine with the Combination of N-acetyl Cysteine and Cimetidine in Acute Acetaminophen Toxicity: A Double-Blinded Clinical Trial. |
| Q45786180 | Comparison of inhibitory effects between acetaminophen-glutathione conjugate and reduced glutathione in human glutathione reductase |
| Q35913165 | Complement activation in acetaminophen-induced liver injury in mice |
| Q43185909 | Cost minimization analysis comparing enteral N-acetylcysteine to intravenous acetylcysteine in the management of acute acetaminophen toxicity |
| Q36221269 | Critical role of c-jun N-terminal protein kinase in promoting mitochondrial dysfunction and acute liver injury |
| Q37317485 | Curcumin protects against acetaminophen-induced apoptosis in hepatic injury |
| Q35195090 | Dendritic cell depletion exacerbates acetaminophen hepatotoxicity |
| Q28551818 | Differential Cytotoxicity of Acetaminophen in Mouse Macrophage J774.2 and Human Hepatoma HepG2 Cells: Protection by Diallyl Sulfide |
| Q33917959 | Differential regulation of mitogen-activated protein kinase pathways by acetaminophen and its nonhepatotoxic regioisomer 3'-hydroxyacetanilide in TAMH cells |
| Q42723225 | Discovery of common urinary biomarkers for hepatotoxicity induced by carbon tetrachloride, acetaminophen and methotrexate by mass spectrometry-based metabolomics. |
| Q36346954 | Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury. |
| Q33755165 | Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis |
| Q46959086 | Drug-induced liver injury: summary of a single topic clinical research conference |
| Q92409348 | Effect of Ketorolac on the Prevention of Postoperative Catheter-Related Bladder Discomfort in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy: A Randomized, Double-Blinded, Placebo-Controlled Study |
| Q37446034 | Emerging role of high-mobility group box 1 (HMGB1) in liver diseases |
| Q35387099 | Encephalopathy in acute liver failure resulting from acetaminophen intoxication: new observations with potential therapy |
| Q36093484 | Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose |
| Q38677995 | Evaluation of a Food and Drug Administration Mandate to Limit Acetaminophen in Prescription Combination Products. |
| Q43137793 | FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable? |
| Q36988910 | Fas receptor-deficient lpr mice are protected against acetaminophen hepatotoxicity due to higher glutathione synthesis and enhanced detoxification of oxidant stress |
| Q47123699 | Fast food diet-induced non-alcoholic fatty liver disease exerts early protective effect against acetaminophen intoxication in mice |
| Q38612550 | Fructose diet alleviates acetaminophen-induced hepatotoxicity in mice. |
| Q43185237 | Gap junction dysfunction reduces acetaminophen hepatotoxicity with impact on apoptotic signaling and connexin 43 protein induction in rat. |
| Q90373313 | Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro |
| Q34622835 | HMGB1 in health and disease |
| Q35141090 | HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity |
| Q36846496 | Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function |
| Q39566852 | Hepatic Overexpression of Annexin A1 and A2 in Thioacetamide-Primed Mice Protects Them Against Acetaminophen-Induced Liver Failure and Death |
| Q46343410 | Hepatitis C is a predictor of acute liver injury among hospitalizations for acetaminophen overdose in the United States: a nationwide analysis |
| Q64929959 | Hepatoprotective Effect of Polysaccharides Isolated from Dendrobium officinale against Acetaminophen-Induced Liver Injury in Mice via Regulation of the Nrf2-Keap1 Signaling Pathway. |
| Q36048880 | Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: involvement of the antioxidant mechanisms |
| Q34632884 | Hepatoprotective activity of Tribulus terrestris extract against acetaminophen-induced toxicity in a freshwater fish (Oreochromis mossambicus). |
| Q35114156 | Hepatoprotective role of liver fatty acid binding protein in acetaminophen induced toxicity. |
| Q37653445 | Hepatotoxicity with Vismodegib: An MD Anderson Cancer Center and Research on Adverse Drug Events and Reports Project |
| Q34262481 | High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity |
| Q52680499 | Honey as a Potential Natural Antioxidant Medicine: An Insight into Its Molecular Mechanisms of Action. |
| Q28218108 | Hospitalizations for acetaminophen overdose: a Canadian population-based study from 1995 to 2004 |
| Q33580844 | Human bone marrow mesenchymal stem cell-derived hepatocytes improve the mouse liver after acute acetaminophen intoxication by preventing progress of injury |
| Q53625939 | Hyperbaric oxygen reduces acetaminophen toxicity and increases HIF-1alpha expression. |
| Q61800882 | Identification of Novel Regulatory Genes in APAP Induced Hepatocyte Toxicity by a Genome-Wide CRISPR-Cas9 Screen |
| Q48192189 | Increased Th1 immune response in SERPINB3 transgenic mice during acute liver failure. |
| Q36407344 | Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2 |
| Q38107461 | Inflammation and liver tumorigenesis |
| Q43701391 | Influence of acetaminophen at therapeutic doses on surrogate markers of severity of acute viral hepatitis. |
| Q34144857 | Influence of small doses of various drug vehicles on acetaminophen-induced liver injury. |
| Q50104614 | Interventions for paracetamol (acetaminophen) overdose |
| Q24246166 | Interventions for paracetamol (acetaminophen) overdose |
| Q40240110 | Involvement of the multidrug resistance P-glycoprotein in acetaminophen-induced toxicity in hepatoma-derived HepG2 and Hep3B cells. |
| Q42120606 | Lactobacillus fermentum Postbiotic-induced Autophagy as Potential Approach for Treatment of Acetaminophen Hepatotoxicity. |
| Q34013719 | Lactoferrin protects against acetaminophen-induced liver injury in mice |
| Q92923570 | Liquid Chromatography-Tandem Mass Spectrometry Analysis of Acetaminophen Covalent Binding to Glutathione S-Transferases |
| Q48294403 | Long-term mortality of acetaminophen poisoning: a nationwide population-based cohort study with 10-year follow-up in Taiwan. |
| Q90608222 | Lonicerae japonicae flos and Lonicerae flos: a systematic review of ethnopharmacology, phytochemistry and pharmacology |
| Q36363960 | Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy |
| Q46959059 | Metabolic insights into the hepatoprotective role of N-acetylcysteine in mouse liver |
| Q37791059 | Methylxanthines, Inflammation, and Cancer: Fundamental Mechanisms |
| Q36648759 | Mitochondrial protein thiol modifications in acetaminophen hepatotoxicity: effect on HMG-CoA synthase |
| Q52630593 | Molecular Adsorbent Recirculating System Treatment Can Reduce Blood Levels of N-Acetylcysteine in Patients With Acetaminophen Overdose: Case Reports. |
| Q36497612 | Mouse liver protein sulfhydryl depletion after acetaminophen exposure |
| Q33849607 | Multiplex cDNA quantification method that facilitates the standardization of gene expression data |
| Q37492578 | N-Acetyl-L-cysteine Protects the Enterocyte against Oxidative Damage by Modulation of Mitochondrial Function |
| Q39094306 | Naturally Occurring Nrf2 Activators: Potential in Treatment of Liver Injury. |
| Q46688268 | Neutrophil depletion protects against murine acetaminophen hepatotoxicity |
| Q43064050 | No evidence demonstrating hepatotoxicity associated with hydroxycitric acid |
| Q53631174 | Opposite roles of neutrophils and macrophages in the pathogenesis of acetaminophen-induced acute liver injury. |
| Q37407996 | Outcomes of patients with acetaminophen-associated toxic hepatitis at a far east poison center |
| Q46070490 | Over-the-counter access to emergency contraception without age restriction: an opinion of the Women's Health Practice and Research Network of the American College of Clinical Pharmacy |
| Q35048149 | Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase |
| Q36640752 | PXR antagonists and implication in drug metabolism |
| Q89495562 | PYP1-4 peptide from Pyropia yezoensis protects against acetaminophen-induced hepatotoxicity in HepG2 cells |
| Q46952527 | Platelet activating factor (PAF) antagonism with ginkgolide B protects the liver against acute injury. importance of controlling the receptor of PAF. |
| Q80101971 | Platelet-activating factor inactivator (rPAF-AH) enhances liver's recovery after paracetamol intoxication |
| Q50131013 | Platelets as Modulators of Liver Diseases |
| Q90524293 | Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity |
| Q34345049 | Pregnane X receptor and drug-induced liver injury. |
| Q37221746 | Prescription-acquired acetaminophen use and the risk of asthma in adults: a case-control study |
| Q37209229 | Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine |
| Q91934497 | Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial) |
| Q37210142 | Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity |
| Q43036372 | Protective effect of Baccharis trimera extract on acute hepatic injury in a model of inflammation induced by acetaminophen |
| Q36907101 | Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity. |
| Q34819836 | Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting |
| Q47779039 | Psychosocial and behavioral factors in acetaminophen-related acute liver failure and liver injury |
| Q39761031 | Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis. |
| Q60918101 | Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a ra |
| Q41895629 | Rational Design of Novel Pyridinol-Fused Ring Acetaminophen Analogues |
| Q79424116 | Recombinant platelet-activating factor-acetylhydrolase attenuates paracetamol-induced liver oxidative stress, injury, and regeneration |
| Q36747725 | Redox Nanoparticle Therapeutics for Acetaminophen-Induced Hepatotoxicity in Mice |
| Q46252513 | Reduced acetaminophen-induced liver injury in mice by genetic disruption of IL-1 receptor antagonist. |
| Q59273487 | Reduction of Acute Hepatic Damage Induced by Acetaminophen after Treatment with Diphenyl Diselenide in Mice |
| Q94543847 | Regulation of macrophage activation in the liver after acute injury: Role of the fibrinolytic system |
| Q34074958 | Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity |
| Q38256342 | Role of Nrf2 in chronic liver disease. |
| Q35202294 | Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage |
| Q37393413 | Role of hepatic resident and infiltrating macrophages in liver repair after acute injury. |
| Q36974467 | Role of neutrophils in the pathogenesis of acute inflammatory liver injury |
| Q36879950 | Role of the Nrf2-ARE pathway in liver diseases |
| Q26747404 | STAT3, a Key Parameter of Cytokine-Driven Tissue Protection during Sterile Inflammation - the Case of Experimental Acetaminophen (Paracetamol)-Induced Liver Damage |
| Q35224589 | Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling |
| Q52588977 | Salicytamide: a New Anti-inflammatory Designed Drug Candidate. |
| Q43265425 | Severe acetaminophen poisoning treated with a fractionated plasma separation and absorption system: A case report |
| Q38205014 | Signalling pathways involved in paracetamol-induced hepatotoxicity: new insights on the role of protein tyrosine phosphatase 1B. |
| Q37012989 | Sorbent-based artificial liver devices: principles of operation, chemical effects and clinical results |
| Q42927523 | Study of the Protective Effect of Teucrium polium L. Extract on Acetaminophen-Induced Hepatotoxicity in Mice |
| Q47881177 | Syndecan-1 limits the progression of liver injury and promotes liver repair in acetaminophen-induced liver injury in mice |
| Q28818435 | TAMH: A Useful In Vitro Model for Assessing Hepatotoxic Mechanisms |
| Q36525204 | TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner |
| Q39367617 | The 100 most influential publications in paracetamol poisoning treatment: a bibliometric analysis of human studies |
| Q47324914 | The Lipid Lowering and Cardioprotective Effects of Vernonia calvoana Ethanol Extract in Acetaminophen-Treated Rats |
| Q46254868 | The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice |
| Q33760064 | The hepatic stem cell niche: identification by label-retaining cell assay |
| Q35842779 | The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) |
| Q81636113 | The pregnane X receptor: from bench to bedside |
| Q33653566 | The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice |
| Q37863654 | The safety of Citrus aurantium (bitter orange) and its primary protoalkaloid p-synephrine |
| Q44947668 | Therapeutic effect of liposomal-N-acetylcysteine against acetaminophen-induced hepatotoxicity |
| Q28579485 | Ubiquitin-dependent degradation of p53 protein despite phosphorylation at its N terminus by acetaminophen |
| Q28571454 | Upregulation of calpastatin in regenerating and developing rat liver: role in resistance against hepatotoxicity |
| Q31131808 | Validation of ICD-9-CM/ICD-10 coding algorithms for the identification of patients with acetaminophen overdose and hepatotoxicity using administrative data |
| Q79793716 | [Is there a risk to prescribe paracetamol at therapeutic doses in patients with acute or chronic liver disease?] |
| Q38187448 | miRNAs and their application in drug-induced liver injury |
| Q35679117 | p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo |
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