Intestinal Epithelial Chemokine (C-C Motif) Ligand 7 Overexpression Enhances Acetaminophen-Induced Hepatotoxicity in Mice

scientific article published on 11 October 2019

Intestinal Epithelial Chemokine (C-C Motif) Ligand 7 Overexpression Enhances Acetaminophen-Induced Hepatotoxicity in Mice is …
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scholarly articleQ13442814

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P356DOI10.1016/J.AJPATH.2019.09.009
P698PubMed publication ID31610172

P2093author name stringYong Jiang
Peng Chen
Neil Kaplowitz
Sanda Win
Zhihong Luo
Mengwei Niu
Shenhai Gong
P2860cites workAcetaminophen absorption and metabolism in an intestine/liver microphysiological systemQ60212326
Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in miceQ88014266
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c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src.Q30009024
Epithelial barriers in homeostasis and diseaseQ34093056
Microbiota and the gut-liver axis: bacterial translocation, inflammation and infection in cirrhosisQ34647371
Acetaminophen hepatotoxicity and acute liver failureQ34657996
HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicityQ35141090
Bacterial translocation and changes in the intestinal microbiome in mouse models of liver diseaseQ35977446
Myosin light chain kinase: pulling the strings of epithelial tight junction functionQ36062835
Cytokine regulation of tight junctionsQ37308566
Bacterial translocation aggravates CCl4-induced liver cirrhosis by regulating CD4+ T cells in ratsQ37612290
Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicityQ37656707
Intestinal bacteria and the regulation of immune cell homeostasisQ37700728
Intestinal epithelial cells: regulators of barrier function and immune homeostasisQ38190874
Acetaminophen hepatotoxicity: an updated reviewQ38299336
Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epitheliumQ38417912
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Acetaminophen-induced stimulation of MDR1 expression and activity in rat intestine and in LS 174T human intestinal cell lineQ39642818
Lipopolysaccharide binding protein inhibitory peptide protects against acetaminophen-induced hepatotoxicityQ39654999
Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis.Q40608400
Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in miceQ41583258
Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in miceQ42556951
Intestinal glucose uptake protects liver from lipopolysaccharide and D-galactosamine, acetaminophen, and alpha-amanitin in miceQ43065171
Acetaminophen changes intestinal epithelial cell membrane properties, subsequently affecting absorption processesQ43605000
The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicityQ46835446
Acute liver failureQ56430379
Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver diseaseQ57110449
Intestinal immune dysregulation driven by dysbiosis promotes barrier disruption and bacterial translocation in rats with cirrhosisQ58556455
Mechanisms regulating intestinal barrier integrity and its pathological implicationsQ58774497
P433issue1
P304page(s)57-67
P577publication date2019-10-11
P1433published inThe American Journal of PathologyQ4744259
P1476titleIntestinal Epithelial Chemokine (C-C Motif) Ligand 7 Overexpression Enhances Acetaminophen-Induced Hepatotoxicity in Mice
P478volume190