| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M211392200 |
| P698 | PubMed publication ID | 12499369 |
| P50 | author | Xingzhi Xu | Q37375592 |
| P2093 | author name string | David F Stern | |
| P2860 | cites work | Linkage of ATM to cell cycle regulation by the Chk2 protein kinase | Q22008502 |
| Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome | Q22011001 | ||
| Identification of genes periodically expressed in the human cell cycle and their expression in tumors | Q29619131 | ||
| Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage | Q29619360 | ||
| p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks | Q30014828 | ||
| Utilization of oriented peptide libraries to identify substrate motifs selected by ATM. | Q30868748 | ||
| Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation | Q33558779 | ||
| 53BP1, a mediator of the DNA damage checkpoint | Q34153067 | ||
| A unified view of the DNA-damage checkpoint | Q34560932 | ||
| The DNA binding domain of the gene 2.5 single-stranded DNA-binding protein of bacteriophage T7. | Q38359396 | ||
| Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage | Q39457941 | ||
| Chk2 activation and phosphorylation-dependent oligomerization | Q39674829 | ||
| The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways | Q40750310 | ||
| The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage | Q41854894 | ||
| Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways | Q41861185 | ||
| The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors | Q42672394 | ||
| The hCds1 (Chk2)-FHA domain is essential for a chain of phosphorylation events on hCds1 that is induced by ionizing radiation | Q43628901 | ||
| Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. | Q43711748 | ||
| Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks | Q43773216 | ||
| Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1. | Q44284890 | ||
| Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways | Q58883742 | ||
| Transport between the cell nucleus and the cytoplasm | Q22065411 | ||
| ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway | Q22253899 | ||
| ATM-dependent phosphorylation of nibrin in response to radiation exposure | Q22254062 | ||
| BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage | Q24292278 | ||
| Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 | Q24311891 | ||
| Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis | Q24515107 | ||
| UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization | Q24531288 | ||
| hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks | Q24644470 | ||
| Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin | Q24672721 | ||
| Megabase chromatin domains involved in DNA double-strand breaks in vivo | Q24680284 | ||
| Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint | Q27937738 | ||
| The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
| DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 | Q28131715 | ||
| Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX | Q28139663 | ||
| Substrate specificities and identification of putative substrates of ATM kinase family members | Q28141080 | ||
| A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage | Q28144576 | ||
| NFBD1/KIAA0170 is a novel nuclear transcriptional transactivator with BRCT domain | Q28145496 | ||
| Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products | Q28145751 | ||
| ATM phosphorylates histone H2AX in response to DNA double-strand breaks | Q28188651 | ||
| Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress | Q28201846 | ||
| ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses | Q28202998 | ||
| Chromosomal stability and the DNA double-stranded break connection | Q28205315 | ||
| ATR and ATRIP: partners in checkpoint signaling | Q28207471 | ||
| Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies | Q28208525 | ||
| Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations | Q28215462 | ||
| Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1 | Q28285538 | ||
| ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage | Q28364113 | ||
| Genomic instability in mice lacking histone H2AX | Q28589826 | ||
| Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks | Q28609912 | ||
| Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways | Q29615271 | ||
| Cell cycle checkpoint signaling through the ATM and ATR kinases | Q29617837 | ||
| Recombinational DNA double-strand breaks in mice precede synapsis | Q29618790 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | DNA damage | Q5205747 |
| P304 | page(s) | 8795-8803 | |
| P577 | publication date | 2002-12-23 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways | |
| P478 | volume | 278 |
| Q24299264 | A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination |
| Q24626425 | A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication |
| Q64390175 | A Perspective on Chromosomal Double Strand Break Markers in Mammalian Cells |
| Q29547735 | ATM and related protein kinases: safeguarding genome integrity |
| Q37624182 | Assembly of checkpoint and repair machineries at DNA damage sites |
| Q33952979 | BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response |
| Q37507563 | BRCA1 and its toolbox for the maintenance of genome integrity |
| Q36325528 | Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks |
| Q36627909 | Candidate protein biodosimeters of human exposure to ionizing radiation. |
| Q28293996 | Cell-cycle checkpoints and cancer |
| Q35906070 | Checking on DNA damage in S phase |
| Q35157595 | Checkpoint mediators: relaying signals from DNA strand breaks |
| Q35371237 | DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells |
| Q39675593 | DNA damage signaling in response to double-strand breaks during mitosis |
| Q90324833 | Dehydroepiandrosterone Induces Temozolomide Resistance Through Modulating Phosphorylation and Acetylation of Sp1 in Glioblastoma |
| Q30483874 | Differential regulation of centrosome integrity by DNA damage response proteins. |
| Q27676862 | Dimerization, but not phosphothreonine binding, is conserved between the forkhead-associated domains of Drosophila MU2 and human MDC1 |
| Q39945678 | Disassembly of MDC1 foci is controlled by ubiquitin-proteasome-dependent degradation |
| Q44548807 | Distinct pathways of nonhomologous end joining that are differentially regulated by DNA-dependent protein kinase-mediated phosphorylation |
| Q90351981 | Estrogen Modulates the Sensitivity of Lung Vagal C Fibers in Female Rats Exposed to Intermittent Hypoxia |
| Q47276758 | Functional Analysis of Human Hub Proteins and Their Interactors Involved in the Intrinsic Disorder-Enriched Interactions |
| Q34579811 | HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability |
| Q35126538 | Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast |
| Q33207461 | Histone H2AX phosphorylation induced by selective photolysis of BrdU-labeled DNA with UV light: relation to cell cycle phase |
| Q42672338 | Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. |
| Q35971184 | Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer |
| Q39705486 | Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability |
| Q38383031 | Interplay between the DNA damage proteins MDC1 and ATM in the regulation of the spindle assembly checkpoint |
| Q34285463 | Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage |
| Q34454221 | MDC1 interacts with Rad51 and facilitates homologous recombination |
| Q64236098 | MRE11 UFMylation promotes ATM activation |
| Q24563397 | Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention |
| Q33658905 | Mediator of DNA damage checkpoint 1 (MDC1) contributes to high NaCl-induced activation of the osmoprotective transcription factor TonEBP/OREBP. |
| Q28213030 | Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control |
| Q22337187 | Microcephalin Is a DNA Damage Response Protein Involved in Regulation of CHK1 and BRCA1 |
| Q39982082 | Modification of the ionizing radiation response in living cells by an scFv against the DNA-dependent protein kinase |
| Q35842531 | Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage |
| Q36204487 | Molecular basis of ataxia telangiectasia and related diseases |
| Q38655248 | Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth. |
| Q28205262 | NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage |
| Q28304255 | NFBD1/MDC1 associates with p53 and regulates its function at the crossroad between cell survival and death in response to DNA damage |
| Q35070481 | NFBD1/MDC1 is phosphorylated by PLK1 and controls G2/M transition through the regulation of a TOPOIIα-mediated decatenation checkpoint |
| Q39546495 | NFBD1/MDC1 regulates Cav1 and Cav2 independently of DNA damage and p53. |
| Q39918729 | NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway |
| Q28212425 | Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains |
| Q37719701 | Phosphorylation of LSD1 by PLK1 promotes its chromatin release during mitosis. |
| Q37802636 | RAD18 lives a double life: Its implication in DNA double-strand break repair |
| Q64388640 | RNF126 Quenches RNF168 Function in the DNA Damage Response |
| Q50077606 | RNF126 as a biomarker of a poor prognosis in invasive breast cancer and CHK1 inhibitor efficacy in breast cancer cells |
| Q39852750 | Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling |
| Q47896370 | Radiosensitization of esophageal cancer cells ECA109 by knockdown of H2AX. |
| Q27310232 | Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors |
| Q34364324 | Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity |
| Q30419946 | Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1 |
| Q27676675 | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain |
| Q28247374 | The DNA damage response mediator MDC1 directly interacts with the anaphase-promoting complex/cyclosome |
| Q37034923 | The DNA damage response pathways: at the crossroad of protein modifications |
| Q39747969 | Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition |
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