| scholarly article | Q13442814 |
| P50 | author | Peter Wright | Q7177800 |
| H. Jane Dyson | Q30513249 | ||
| Tsaffrir Zor | Q55293667 | ||
| Natalie K Goto | Q58183035 | ||
| P2093 | author name string | Maria Martinez-Yamout | |
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| Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions | Q27748755 | ||
| A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors | Q27860552 | ||
| NMRPipe: a multidimensional spectral processing system based on UNIX pipes | Q27860859 | ||
| NMR View: A computer program for the visualization and analysis of NMR data | Q27860951 | ||
| The myb gene family in cell growth, differentiation and apoptosis | Q28137891 | ||
| A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes | Q28141757 | ||
| MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines | Q28142772 | ||
| Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators | Q28219104 | ||
| Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP | Q28295041 | ||
| Orchestrated response: a symphony of transcription factors for gene control | Q28679048 | ||
| Rapid measurement of binding constants and heats of binding using a new titration calorimeter | Q29547842 | ||
| Transcriptional activation by recruitment | Q29615048 | ||
| 1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects | Q29616506 | ||
| Altered Hox expression and segmental identity in Mll-mutant mice | Q29620391 | ||
| Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation | Q31998382 | ||
| The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex | Q32068521 | ||
| Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia | Q33652400 | ||
| An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300 | Q33777090 | ||
| ATP-dependent chromatin-remodeling complexes. | Q33786898 | ||
| Gli genes in development and cancer | Q33814305 | ||
| An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines | Q33854728 | ||
| Role of secondary structure in discrimination between constitutive and inducible activators | Q33958946 | ||
| Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation | Q33962241 | ||
| Cubitus interruptus requires Drosophila CREB-binding protein to activate wingless expression in the Drosophila embryo | Q33962273 | ||
| Molecular interactions involved in the transactivation of the human T-cell leukemia virus type 1 promoter mediated by Tax and CREB-2 (ATF-4). | Q33963343 | ||
| Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins | Q34405465 | ||
| 11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene | Q35865236 | ||
| Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. | Q35987119 | ||
| Differential expression of the amv gene in human hematopoietic cells | Q36289210 | ||
| Myb: a transcriptional activator linking proliferation and differentiation in hematopoietic cells. | Q36354824 | ||
| Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivation | Q36571545 | ||
| Mechanism by which the IFN-beta enhanceosome activates transcription | Q36666284 | ||
| Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development | Q36745250 | ||
| MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis | Q37478854 | ||
| Myb and Ets proteins cooperate to transactivate an early myeloid gene | Q38296597 | ||
| Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors | Q38312442 | ||
| A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis | Q38335144 | ||
| Effects of HOX homeobox genes in blood cell differentiation | Q38341754 | ||
| Magnitude of the CREB-dependent transcriptional response is determined by the strength of the interaction between the kinase-inducible domain of CREB and the KIX domain of CREB-binding protein | Q39540298 | ||
| Core binding factor cannot synergistically activate the myeloperoxidase proximal enhancer in immature myeloid cells without c-Myb | Q40023226 | ||
| Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types | Q41558201 | ||
| The enhanceosome and transcriptional synergy. | Q41715800 | ||
| The CREB-binding protein (CBP) cooperates with the serum response factor for transactivation of the c-fos serum response element | Q42447720 | ||
| A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias | Q44069634 | ||
| Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription | Q44445912 | ||
| Binding of p53 to the KIX domain of CREB binding protein. A potential link to human T-cell leukemia virus, type I-associated leukemogenesis | Q45747438 | ||
| Isolation and characterization of a pufferfish MLL (mixed lineage leukemia)-like gene (fMll) reveals evolutionary conservation in vertebrate genes related to Drosophila trithorax | Q47775825 | ||
| Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals. | Q50335838 | ||
| Analysis of CREB mutants in Tax complex formation and trans-activation. | Q55239896 | ||
| Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP. | Q55240568 | ||
| Structural analyses of CREB-CBP transcriptional activator-coactivator complexes by NMR spectroscopy: implications for mapping the boundaries of structural domains | Q57078248 | ||
| Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients | Q57912400 | ||
| P433 | issue | 45 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | leukemia | Q29496 |
| P1104 | number of pages | 7 | |
| P304 | page(s) | 43168-43174 | |
| P577 | publication date | 2002-08-29 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domain | |
| P478 | volume | 277 |
| Q27650217 | A nuclear receptor-like pathway regulating multidrug resistance in fungi |
| Q27678036 | Allosteric Communication in the KIX Domain Proceeds through Dynamic Repacking of the Hydrophobic Core |
| Q34082986 | Allostery within a transcription coactivator is predominantly mediated through dissociation rate constants |
| Q41993123 | Amphipathic small molecules mimic the binding mode and function of endogenous transcription factors |
| Q37182653 | Amplification of signaling via cellular allosteric relay and protein disorder |
| Q24294691 | An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis |
| Q64289561 | An order-to-disorder structural switch activates the FoxM1 transcription factor |
| Q27679909 | Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription |
| Q35067189 | Assessing the permissiveness of transcriptional activator binding sites |
| Q33327692 | Binding-induced folding of a natively unstructured transcription factor. |
| Q37401763 | Boosting transcription by transcription: enhancer-associated transcripts. |
| Q39869280 | Conformational Ensembles of an Intrinsically Disordered Protein pKID with and without a KIX Domain in Explicit Solvent Investigated by All-Atom Multicanonical Molecular Dynamics |
| Q34205849 | Conformational control of the binding of the transactivation domain of the MLL protein and c-Myb to the KIX domain of CREB |
| Q35946120 | Conformational propensities of intrinsically disordered proteins influence the mechanism of binding and folding |
| Q24304641 | Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression |
| Q24670517 | Critical role for a single leucine residue in leukemia induction by E2A-PBX1 |
| Q52679677 | DNA binding and phosphorylation induce conformational alterations in the kinase-inducible domain of CREB. Implications for the mechanism of transcription function. |
| Q39148669 | Deciphering the mechanisms of binding induced folding at nearly atomic resolution: The Φ value analysis applied to IDPs |
| Q47821476 | Deciphering the promiscuous interactions between intrinsically disordered transactivation domains and the KIX domain. |
| Q34083040 | Dissecting allosteric effects of activator-coactivator complexes using a covalent small molecule ligand |
| Q50070855 | Dual Labeling of the CBP/p300 KIX domain for 19F NMR leads to identification of a new small molecule binding site. |
| Q42824174 | E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells |
| Q57170998 | Expanding the Paradigm: Intrinsically Disordered Proteins and Allosteric Regulation |
| Q34197530 | Expanding the proteome: disordered and alternatively folded proteins |
| Q58217754 | Experimental Results |
| Q93089162 | Explicit Characterization of the Free Energy Landscape of pKID-KIX Coupled Folding and Binding |
| Q39085729 | FP Tethering: a screening technique to rapidly identify compounds that disrupt protein-protein interactions |
| Q90781762 | Folding Free Energy Landscape of Ordered and Intrinsically Disordered Proteins |
| Q87135307 | Free-energy landscape of intrinsically disordered proteins investigated by all-atom multicanonical molecular dynamics |
| Q41001131 | Functional redundancy between the transcriptional activation domains of E2A is mediated by binding to the KIX domain of CBP/p300. |
| Q35114430 | HTLV-1 HBZ protein deregulates interactions between cellular factors and the KIX domain of p300/CBP. |
| Q41978045 | Hamiltonian Mapping Revisited: Calibrating Minimalist Models to Capture Molecular Recognition by Intrinsically Disordered Proteins |
| Q31134749 | Identification of small-molecule antagonists that inhibit an activator: coactivator interaction |
| Q26768540 | Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies |
| Q22061731 | Intrinsically unstructured proteins and their functions |
| Q47151585 | KIXBASE: A comprehensive web resource for identification and exploration of KIX domains. |
| Q24304256 | Leu628 of the KIX domain of CBP is a key residue for the interaction with the MLL transactivation domain |
| Q24650130 | Mapping the interactions of the p53 transactivation domain with the KIX domain of CBP |
| Q40210194 | Mechanism of coupled folding and binding of an intrinsically disordered protein |
| Q33943731 | Mixed lineage leukemia: a structure-function perspective of the MLL1 protein |
| Q43085639 | Molecular Basis for the Mechanism of Constitutive CBP/p300 Coactivator Recruitment by CRTC1-MAML2 and Its Implications in cAMP Signaling |
| Q36615930 | Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein |
| Q31026926 | Molecular Recognition of Protein Surfaces: High Affinity Ligands for the CBP KIX Domain |
| Q36087279 | Molecular characterization of HTLV-1 Tax interaction with the KIX domain of CBP/p300. |
| Q34386314 | Molecular recognition by the KIX domain and its role in gene regulation |
| Q38347957 | Mutational analysis of the KIX domain of CBP reveals residues critical for SREBP binding |
| Q33600399 | Mutations of Chromatin Structure Regulating Genes in Human Malignancies |
| Q36520402 | NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1. |
| Q27676154 | Ordering a Dynamic Protein Via a Small-Molecule Stabilizer |
| Q90439339 | Overview of Relaxation Dispersion NMR Spectroscopy to Study Protein Dynamics and Protein-Ligand Interactions |
| Q47215625 | Peptidomimetic blockade of MYB in acute myeloid leukemia |
| Q35169776 | Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis |
| Q34082751 | Prepaying the entropic cost for allosteric regulation in KIX |
| Q42284251 | Profiling the dynamic interfaces of fluorinated transcription complexes for ligand discovery and characterization |
| Q31039692 | Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell |
| Q33826548 | RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase |
| Q42935134 | Remarkably fast coupled folding and binding of the intrinsically disordered transactivation domain of cMyb to CBP KIX. |
| Q88500710 | Resolving biomolecular motion and interactions by R2 and R1ρ relaxation dispersion NMR |
| Q39838387 | Retinoid signaling and neurogenin2 function are coupled for the specification of spinal motor neurons through a chromatin modifier CBP |
| Q37183096 | Retroviral proteomics and interactomes: intricate balances of cell survival and viral replication |
| Q38033019 | Role and potential for therapeutic targeting of MYB in leukemia |
| Q36727341 | Role of Intrinsic Protein Disorder in the Function and Interactions of the Transcriptional Coactivators CREB-binding Protein (CBP) and p300 |
| Q37662267 | Role of RbBP5 and H3K4me3 in the vicinity of Snail transcription start site during epithelial-mesenchymal transition in prostate cancer cell |
| Q37011508 | Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300. |
| Q47229962 | Sequence and expression analyses of KIX domain proteins suggest their importance in seed development and determination of seed size in rice, and genome stability in Arabidopsis |
| Q34456840 | Shared structural features of the 9aaTAD family in complex with CBP. |
| Q38256411 | Situational awareness: regulation of the myb transcription factor in differentiation, the cell cycle and oncogenesis. |
| Q90083224 | Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein |
| Q57049907 | Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain |
| Q27653760 | Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains |
| Q34553972 | Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-κB and transcription regulatory factors |
| Q37173275 | Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system |
| Q34387213 | Targeting CREB for cancer therapy: friend or foe |
| Q34540086 | The 9aaTAD Transactivation Domains: From Gal4 to p53. |
| Q42727197 | The CBP/p300 TAZ1 domain in its native state is not a binding partner of MDM2. |
| Q37143502 | The allosteric communication pathways in KIX domain of CBP |
| Q36483412 | The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB. |
| Q42199690 | The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb |
| Q37359180 | The origin of allosteric functional modulation: multiple pre-existing pathways |
| Q36328456 | The robotic mouse: unravelling the function of AF4 in the cerebellum |
| Q31147980 | The role of HTS in drug discovery at the University of Michigan. |
| Q36841870 | Thermodynamic characterization of the interaction between CAR-RXR and SRC-1 peptide by isothermal titration calorimetry |
| Q42116808 | Transcriptional tools: Small molecules for modulating CBP KIX-dependent transcriptional activators |
| Q34035076 | Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition. |
| Q37593646 | Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing. |
| Q92099533 | Why are so many MLL lysine methyltransferases required for normal mammalian development? |
| Q33604849 | c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis |
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