Human connexin26 and connexin30 form functional heteromeric and heterotypic channels

scientific article (publication date: September 2007)

Human connexin26 and connexin30 form functional heteromeric and heterotypic channels is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPCELL.00011.2007
P698PubMed publication ID17615163
P5875ResearchGate publication ID6223094

P50authorThomas W. WhiteQ42427523
P2093author name stringSteven S Scherer
Peter R Brink
Junxian Zhang
Sabrina W Yum
Virginijus Valiunas
Giedrius Kanaporis
P2860cites workCrystal structure of the Aequorea victoria green fluorescent proteinQ27733214
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Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potentialQ28218302
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Expression of the gap-junction connexins 26 and 30 in the rat cochleaQ28287580
Gap junctions in the rat cochlea: immunohistochemical and ultrastructural analysisQ28300307
Gating properties of gap junction channels assembled from connexin43 and connexin43 fused with green fluorescent proteinQ28367650
Gap junctions in the inner ear: comparison of distribution patterns in different vertebrates and assessement of connexin composition in mammalsQ28508885
Gap junction channels formed by coexpressed connexin40 and connexin43Q28576324
Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cellsQ29547331
Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafnessQ30478884
Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell deathQ30578611
Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activationQ31135115
Species-specific voltage-gating properties of connexin-45 junctions expressed in Xenopus oocytesQ33907175
Intracellular domains of mouse connexin26 and -30 affect diffusional and electrical properties of gap junction channelsQ33952503
Gap junction-mediated intercellular biochemical coupling in cochlear supporting cells is required for normal cochlear functionsQ34084948
Structural and functional diversity of connexin genes in the mouse and human genomeQ34137753
Mechanisms of Cx43 and Cx26 transport to the plasma membrane and gap junction regenerationQ34450643
Potassium ion recycling pathway via gap junction systems in the mammalian cochlea and its interruption in hereditary nonsyndromic deafnessQ34505515
High-resolution FRET microscopy of cholera toxin B-subunit and GPI-anchored proteins in cell plasma membranesQ34709520
Peering inside lipid rafts and caveolaeQ34825921
Nonredundant Gap Junction FunctionsQ35128775
Connexin gene pathologyQ35161187
Functional consequences of heterogeneous gap junction channel formation and its influence in health and diseaseQ36162581
Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 A using imaging fluorescence resonance energy transferQ36256233
Expression of a connexin 43/beta-galactosidase fusion protein inhibits gap junctional communication in NIH3T3 cellsQ36382571
Distinct and gradient distributions of connexin26 and connexin30 in the cochlear sensory epithelium of guinea pigsQ36908171
Fluorescence energy transfer reveals microdomain formation at physiological temperatures in lipid mixtures modeling the outer leaflet of the plasma membraneQ40247658
Gap-junctional single-channel permeability for fluorescent tracers in mammalian cell culturesQ40288658
Fluorescence resonance energy transferQ40398693
Cochlear gap junctions coassembled from Cx26 and 30 show faster intercellular Ca2+ signaling than homomeric counterparts.Q40461910
Quantitative fluorescence resonance energy transfer (FRET) measurement with acceptor photobleaching and spectral unmixingQ40524681
Transport and function of cx26 mutants involved in skin and deafness disorders.Q40542422
Connexin43 and connexin26 form gap junctions, but not heteromeric channels in co-expressing cellsQ40558677
Resonance energy transfer: methods and applicationsQ40684664
The gap junction communication channelQ40974984
Connections with connexins: the molecular basis of direct intercellular signalingQ41006464
Multiple connexin proteins in single intercellular channels: connexin compatibility and functional consequencesQ41141420
Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cellsQ41665390
Scrape-loading and dye transfer. A rapid and simple technique to study gap junctional intercellular communicationQ43521106
Hydrogen peroxide inhibits gap junctional coupling and modulates intracellular free calcium in cochlear Hensen cells.Q43649289
The effects of cytoplasmic acidification upon electrical coupling in the organ of CortiQ44968909
Altered permeability and modulatory character of connexin channels during mammary gland developmentQ44987231
Impaired permeability to Ins(1,4,5)P3 in a mutant connexin underlies recessive hereditary deafnessQ45183609
Compartmentalized and signal-selective gap junctional coupling in the hearing cochlea.Q46911582
Perspectives: biomedicine. The benefits of recyclingQ48110744
Evidence for the co-localization of another connexin with connexin-43 at astrocytic gap junctions in rat brainQ48720791
Species specificity of mammalian connexin-26 to form open voltage-gated hemichannels.Q50460921
Mutations in the gene for connexin 26 (GJB2) that cause hearing loss have a dominant negative effect on connexin 30.Q50484268
Connexin interaction patterns in keratinocytes revealed morphologically and by FRET analysis.Q50774956
Biophysical properties of mouse connexin30 gap junction channels studied in transfected human HeLa cells.Q53926502
Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctionsQ59212248
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)C1032-48
P577publication date2007-09-01
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleHuman connexin26 and connexin30 form functional heteromeric and heterotypic channels
P478volume293

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