| scholarly article | Q13442814 |
| P50 | author | Andrew J Wood | Q37375156 |
| Philip D Gregory | Q54131584 | ||
| Edward Rebar | Q56842111 | ||
| Fyodor Urnov | Q60057726 | ||
| Lei Zhang | Q79298697 | ||
| Xiangdong Meng | Q117751691 | ||
| P2093 | author name string | Barbara J Meyer | |
| Jeffrey C Miller | |||
| Catherine S Pickle | |||
| Edward J Ralston | |||
| Andrew H Lee | |||
| Te-Wen Lo | |||
| Bryan Zeitler | |||
| Elo Leung | |||
| Rainier Amora | |||
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| Genome editing with engineered zinc finger nucleases | Q28290795 | ||
| Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures | Q28299915 | ||
| A TALE nuclease architecture for efficient genome editing | Q28301656 | ||
| Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases | Q29615069 | ||
| Single-copy insertion of transgenes in Caenorhabditis elegans | Q29617695 | ||
| Targeting X chromosomes for repression | Q34003258 | ||
| Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells | Q35133826 | ||
| TAL effectors: finding plant genes for disease and defense | Q37767018 | ||
| P433 | issue | 6040 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 307 | |
| P577 | publication date | 2011-07-15 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Targeted genome editing across species using ZFNs and TALENs | |
| P478 | volume | 333 |
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| Q37213389 | Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila |
| Q37392808 | Comparison of TALEN scaffolds in Xenopus tropicalis |
| Q38557791 | Concise Review: Patient-Derived Stem Cell Research for Monogenic Disorders |
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| Q28647654 | Construction of a self-cloning system in the unicellular green alga Pseudochoricystis ellipsoidea |
| Q40396022 | Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases. |
| Q38687781 | Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDS. |
| Q29615793 | DNA targeting specificity of RNA-guided Cas9 nucleases |
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| Q34201832 | Dependence of the sperm/oocyte decision on the nucleosome remodeling factor complex was acquired during recent Caenorhabditis briggsae evolution |
| Q97092110 | Design and Derivation of Multi-Reporter Pluripotent Stem Cell Lines via CRISPR/Cas9n-Mediated Homology-Directed Repair |
| Q35422003 | Determining the specificities of TALENs, Cas9, and other genome-editing enzymes |
| Q41504240 | Development of a versatile and conventional technique for gene disruption in filamentous fungi based on CRISPR-Cas9 technology |
| Q22252341 | Discovery and resupply of pharmacologically active plant-derived natural products: A review |
| Q46440057 | Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing |
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| Q51263172 | Efficient TALEN construction and evaluation methods for human cell and animal applications. |
| Q34994351 | Efficient TALEN construction for Bombyx mori gene targeting |
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| Q35931459 | Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9 |
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| Q34425833 | Engineering designer transcription activator-like effector nucleases (TALENs) by REAL or REAL-Fast assembly |
| Q38056410 | Engineering imaging probes and molecular machines for nanomedicine |
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| Q38964283 | Enhanced gene disruption by programmable nucleases delivered by a minicircle vector |
| Q26861350 | Epigenome engineering in cancer: fairytale or a realistic path to the clinic? |
| Q92928116 | Ethics assessment in research proposals adopting CRISPR technology |
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| Q39011134 | Gene Targeting Without DSB Induction Is Inefficient in Barley |
| Q38726631 | Gene editing in birds takes flight. |
| Q50610935 | Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus. |
| Q38060592 | Gene knockout and knockin by zinc-finger nucleases: current status and perspectives |
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| Q34160912 | Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing. |
| Q33674499 | Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells |
| Q33777855 | Genetic and epigenetic control of gene expression by CRISPR-Cas systems |
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| Q27024130 | Genetic and genomic tools for the marine annelid Platynereis dumerilii |
| Q35652611 | Genetics of juvenile idiopathic arthritis: new tools bring new approaches. |
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| Q51840886 | Genome Editing of C. elegans. |
| Q52688164 | Genome Writing: Current Progress and Related Applications. |
| Q39227817 | Genome editing approaches: manipulating of lovastatin and taxol synthesis of filamentous fungi by CRISPR/Cas9 system |
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| Q55054727 | Heritable gene targeting in zebrafish using customized TALENs. |
| Q35112105 | Heritable multiplex genetic engineering in rats using CRISPR/Cas9. |
| Q83225630 | Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9 |
| Q34755909 | High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design |
| Q40712721 | High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos |
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| Q36909774 | High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases. |
| Q35143589 | High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells |
| Q34427918 | Highly efficient and specific genome editing in silkworm using custom TALENs |
| Q36228544 | Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs |
| Q35153109 | Highly specific contractions of a single CAG/CTG trinucleotide repeat by TALEN in yeast. |
| Q27023722 | Homing endonucleases: DNA scissors on a mission |
| Q35977923 | Immunoblot screening of CRISPR/Cas9-mediated gene knockouts without selection |
| Q38243939 | Impact of RNA-guided technologies for target identification and deconvolution |
| Q34289107 | Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs). |
| Q38949154 | Inactivation of Phaeodactylum tricornutum urease gene using transcription activator-like effector nuclease-based targeted mutagenesis |
| Q34525438 | Induced Pluripotent Stem Cells Meet Genome Editing |
| Q37995010 | Induced pluripotent stem cells and severe combined immunodeficiency: merely disease modeling or potentially a novel cure? |
| Q35018507 | Inheritable and precise large genomic deletions of non-coding RNA genes in zebrafish using TALENs |
| Q42240373 | Inhibiting replication of begomoviruses using artificial zinc finger nucleases that target viral-conserved nucleotide motif. |
| Q37037229 | Innovation in academic chemical screening: filling the gaps in chemical biology |
| Q64762178 | Interrogating Parkinson's disease associated redox targets: Potential application of CRISPR editing |
| Q26830468 | Introduction to germ cell development in Caenorhabditis elegans |
| Q30300051 | Knockout of the adp gene related with colonization in Bacillus nematocida B16 using customized transcription activator-like effectors nucleases |
| Q55054726 | Knockout rats generated by embryo microinjection of TALENs. |
| Q36135110 | Life in the fast lane: mammalian disease models in the genomics era. |
| Q27010108 | Making designer mutants in model organisms |
| Q26740311 | Mapping paths: new approaches to dissect eukaryotic signaling circuitry |
| Q27331430 | Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle |
| Q34150507 | Methods for targeted mutagenesis in zebrafish using TALENs |
| Q26741958 | Methods of Genome Engineering: a New Era of Molecular Biology |
| Q36945218 | Minireview: Genome Editing of Human Pluripotent Stem Cells for Modeling Metabolic Disease. |
| Q38598073 | Modeling Disease In Vivo With CRISPR/Cas9. |
| Q37968206 | Modeling human neurodegenerative diseases in transgenic systems |
| Q37974831 | Modular recognition of nucleic acids by PUF, TALE and PPR proteins |
| Q38243804 | Molecular biology approaches in bioadhesion research |
| Q46645932 | More options for gene editing |
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| Q24609428 | Multiplex genome engineering using CRISPR/Cas systems |
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| Q37656497 | Nanomedicine: tiny particles and machines give huge gains |
| Q41436826 | New Biotechnological Tools for the Genetic Improvement of Major Woody Fruit Species |
| Q37662636 | New and TALENted genome engineering toolbox |
| Q41383078 | New techniques and tools in 2011 |
| Q42322559 | Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases |
| Q26742111 | Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation |
| Q35025959 | Nuclease-mediated gene editing by homologous recombination of the human globin locus |
| Q38175498 | Nuclease-mediated genome editing: At the front-line of functional genomics technology |
| Q41812045 | Oligonucleotide delivery by nucleofection does not rescue the reduced proliferation phenotype of gene-edited cells |
| Q64039678 | Opportunities and Challenges for Molecular Understanding of Ciliopathies-The 100,000 Genomes Project |
| Q37236715 | Optimization of scarless human stem cell genome editing |
| Q43761427 | Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease. |
| Q48300051 | Optimized co-transfection of murine embryonic stem cells |
| Q26778501 | Origins of Programmable Nucleases for Genome Engineering |
| Q99603700 | Peel-1 negative selection promotes screening-free CRISPR-Cas9 genome editing in Caenorhabditis elegans |
| Q37256433 | Pluripotent stem cell models of human heart disease |
| Q64957232 | Potential Application of TALENs against Murine Cytomegalovirus Latent Infections. |
| Q37194743 | Precise and heritable genome editing in evolutionarily diverse nematodes using TALENs and CRISPR/Cas9 to engineer insertions and deletions |
| Q48102459 | Precise editing of CLAVATA genes in Brassica napus L. regulates multilocular silique development |
| Q38289442 | Primary immunodeficiencies: a decade of shifting paradigms, the current status and the emergence of cutting-edge therapies and diagnostics |
| Q36490741 | Proliferation of genetically modified human cells on electrospun nanofiber scaffolds |
| Q99417440 | RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges |
| Q33911868 | Random mutagenesis analysis and identification of a novel C2H2-type transcription factor from the nematode-trapping fungus Arthrobotrys oligospora |
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| Q35050871 | Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair |
| Q37661378 | Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization |
| Q37532863 | Rapid creation of forward-genetics tools for C. briggsae using TALENs: lessons for nonmodel organisms |
| Q46395427 | Rapid generation of genetic diversity by multiplex CRISPR/Cas9 genome editing in rice |
| Q54974860 | Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods. |
| Q35630262 | Rapid prototyping of microbial cell factories via genome-scale engineering. |
| Q37296970 | Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics |
| Q26773752 | Rendering the Intractable More Tractable: Tools from Caenorhabditis elegans Ripe for Import into Parasitic Nematodes |
| Q38304212 | Repair of single-point mutations by polypurine reverse Hoogsteen hairpins |
| Q21133603 | Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloning |
| Q38670133 | Research on genodermatoses using novel genome-editing tools |
| Q37680338 | SAPTA: a new design tool for improving TALE nuclease activity |
| Q38848999 | Screening of mRNA Chemical Modification to Maximize Protein Expression with Reduced Immunogenicity. |
| Q42784808 | Sculpting genomes with a hammer and chisel |
| Q34153816 | Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac |
| Q38829554 | Sexual plasticity: A fishy tale |
| Q45901069 | Site-specific gene targeting using transcription activator-like effector (TALE)-based nuclease in Brassica oleracea. |
| Q38586389 | Stable gene replacement in barley by targeted double-strand break induction |
| Q34845881 | Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells |
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| Q46783752 | Structure, transcription and post-transcriptional regulation of the bread wheat orthologs of the barley cleistogamy gene Cly1. |
| Q40654970 | Synthetic mRNA: Production, Introduction into Cells, and Physiological Consequences |
| Q38621515 | Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization |
| Q36088336 | TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction |
| Q36320913 | TAL effectors mediate high-efficiency transposition of the piggyBac transposon in silkworm Bombyx mori L |
| Q37940951 | TAL effectors: customizable proteins for DNA targeting |
| Q38109405 | TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins |
| Q42906173 | TAL effectors: tools for DNA targeting |
| Q34394269 | TALEN and CRISPR/Cas Genome Editing Systems: Tools of Discovery. |
| Q38983286 | TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism |
| Q53587180 | TALEN utilization in rice genome modifications. |
| Q52770186 | TALEN-mediated Drosophila genome editing: protocols and applications. |
| Q33625156 | TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys |
| Q47109251 | TALEN-mediated gene mutations in monkeys. |
| Q33702173 | TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells |
| Q38233430 | TALEN-mediated genome editing: prospects and perspectives |
| Q37543719 | TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome. |
| Q37234547 | TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs |
| Q33698693 | TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity |
| Q36540717 | TALENs: a widely applicable technology for targeted genome editing |
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| Q36686560 | Targeted disruption of sp7 and myostatin with CRISPR-Cas9 results in severe bone defects and more muscular cells in common carp |
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| Q51139534 | Targeted mutagenesis in sea urchin embryos using TALENs. |
| Q24599859 | Targeting DNA With Fingers and TALENs |
| Q37148023 | The CRISPR/Cas9 system for gene editing and its potential application in pain research |
| Q33796268 | The DEP domain-containing protein TOE-2 promotes apoptosis in the Q lineage of C. elegans through two distinct mechanisms |
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