| scholarly article | Q13442814 |
| P50 | author | Lei Zhang | Q79298697 |
| Yannick Doyon | Q37382505 | ||
| Farhoud Faraji | Q42756919 | ||
| Philip D Gregory | Q54131584 | ||
| Edward Rebar | Q56842111 | ||
| Fyodor Urnov | Q60057726 | ||
| P2093 | author name string | Jeffrey C Miller | |
| Sharon L Amacher | |||
| Jasmine M McCammon | |||
| George E Katibah | |||
| Catherine Ngo | |||
| Rainier Amora | |||
| Toby D Hocking | |||
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| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Danio rerio | Q169444 |
| biomedical engineering | Q327092 | ||
| bioengineering | Q580689 | ||
| P304 | page(s) | 702-8 | |
| P577 | publication date | 2008-06-01 | |
| P1433 | published in | Nature Biotechnology | Q1893837 |
| P1476 | title | Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases | |
| P478 | volume | 26 |
| Q59360160 | A Collection of Transgenic Medaka Strains for Efficient Site-Directed Transgenesis Mediated by phiC31 Integrase |
| Q92378292 | A Practical Guide to Genome Editing Using Targeted Nuclease Technologies |
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| Q36057568 | A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR. |
| Q30496374 | A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease |
| Q38201212 | A guide to genome engineering with programmable nucleases |
| Q39220822 | A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish |
| Q51467581 | A highly effective TALEN-mediated approach for targeted gene disruption in Xenopus tropicalis and zebrafish. |
| Q50066031 | A highly specific SpCas9 variant is identified by in vivo screening in yeast. |
| Q36619882 | A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly |
| Q41994593 | A mobile insulator system to detect and disrupt cis-regulatory landscapes in vertebrates |
| Q34205743 | A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. |
| Q50495165 | A novel arrangement of zinc finger nuclease system for in vivo targeted genome engineering: the tomato LEC1-LIKE4 gene case. |
| Q42417041 | A novel cold-sensitive mutant of ntla reveals temporal roles of brachyury in zebrafish |
| Q41845562 | A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity |
| Q37294140 | A novel technique based on in vitro oocyte injection to improve CRISPR/Cas9 gene editing in zebrafish. |
| Q41959958 | A novel zinc-finger nuclease platform with a sequence-specific cleavage module. |
| Q24657663 | A primer for morpholino use in zebrafish. |
| Q33745521 | A simple strategy for heritable chromosomal deletions in zebrafish via the combinatorial action of targeting nucleases |
| Q37094235 | A systematic genome-wide analysis of zebrafish protein-coding gene function |
| Q38214055 | A tale of two models: mouse and zebrafish as complementary models for lymphatic studies |
| Q34059478 | A time-invariant principle of genome evolution |
| Q45096961 | Activation domains for controlling plant gene expression using designed transcription factors |
| Q38877482 | Activities and specificities of homodimeric TALENs in Saccharomyces cerevisiae. |
| Q41901647 | Adding fingers to an engineered zinc finger nuclease can reduce activity |
| Q30386096 | Advancements in zebrafish applications for 21st century toxicology. |
| Q38028180 | Advances in targeted genome editing |
| Q38691942 | Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9. |
| Q37610145 | Advancing toxicology research using in vivo high throughput toxicology with small fish models |
| Q38831338 | Allograft Cancer Cell Transplantation in Zebrafish |
| Q55249537 | An Efficient CRISPR/Cas9 Platform for Rapidly Generating Simultaneous Mutagenesis of Multiple Gene Homoeologs in Allotetraploid Oilseed Rape. |
| Q21128790 | An essential role for maternal control of Nodal signaling |
| Q55014350 | An optimised pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridisation. |
| Q34250428 | An optimized two-finger archive for ZFN-mediated gene targeting |
| Q28534870 | An over expression APP model for anti-Alzheimer disease drug screening created by zinc finger nuclease technology |
| Q33575355 | Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction |
| Q33997893 | Analysis of the retina in the zebrafish model |
| Q44399844 | Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells. |
| Q47690667 | Application of dead end-knockout zebrafish as recipients of germ cell transplantation. |
| Q26776515 | Applications of CRISPR-Cas systems in neuroscience |
| Q38831318 | Approaches to Inactivate Genes in Zebrafish |
| Q33408789 | Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels |
| Q48457178 | Automated visual choice discrimination learning in zebrafish (Danio rerio). |
| Q34401485 | Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion. |
| Q36719581 | Biallelic editing of a lamprey genome using the CRISPR/Cas9 system |
| Q43076954 | Big fish in the genome era. |
| Q38054450 | Biological and biomedical applications of engineered nucleases |
| Q34016420 | CBFβ and RUNX1 are required at 2 different steps during the development of hematopoietic stem cells in zebrafish |
| Q41721624 | CCR5 Gene Editing of Resting CD4(+) T Cells by Transient ZFN Expression From HIV Envelope Pseudotyped Nonintegrating Lentivirus Confers HIV-1 Resistance in Humanized Mice |
| Q39276137 | CHO-gmt5, a novel CHO glycosylation mutant for producing afucosylated and asialylated recombinant antibodies |
| Q64937079 | CRISPR-Cas9 Mediated Genome Editing in Bicyclus anynana Butterflies. |
| Q36370882 | CRISPR-STAT: an easy and reliable PCR-based method to evaluate target-specific sgRNA activity |
| Q57493121 | CRISPR/Cas9 System: A Bacterial Tailor for Genomic Engineering |
| Q37559474 | CRISPR/Cas9 in zebrafish: an efficient combination for human genetic diseases modeling |
| Q44022346 | CRISPR/Cas9-mediated targeted mutagenesis in Nicotiana tabacum |
| Q92408890 | Cas Endonuclease Technology-A Quantum Leap in the Advancement of Barley and Wheat Genetic Engineering |
| Q55281542 | Cattle with a precise, zygote-mediated deletion safely eliminate the major milk allergen beta-lactoglobulin. |
| Q37950979 | Cell Biology Symposium: Zinc finger nucleases to create custom-designed modifications in the swine (Sus scrofa) genome. |
| Q28538875 | Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering |
| Q54404041 | Characterization of immunoglobulin heavy chain knockout rats. |
| Q37820263 | Chemical approaches towards unravelling kinase-mediated signalling pathways |
| Q34423547 | Chimeric TALE recombinases with programmable DNA sequence specificity |
| Q37080386 | Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. |
| Q37825815 | Cilia in cell signaling and human disorders |
| Q40139400 | Comparative analysis of chimeric ZFP-, TALE- and Cas9-piggyBac transposases for integration into a single locus in human cells |
| Q37872274 | Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells |
| Q34030982 | Conditional gene-trap mutagenesis in zebrafish |
| Q82793602 | Construction and testing of engineered zinc-finger proteins for sequence-specific modification of mtDNA |
| Q38732235 | Corticotropin-releasing hormone: Mediator of vertebrate life stage transitions? |
| Q28298846 | Creating designed zinc-finger nucleases with minimal cytotoxicity |
| Q37331954 | Cryopreservation and in vitro fertilization at the zebrafish international resource center |
| Q52430907 | CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair. |
| Q45016625 | Current genomic editing approaches in avian transgenesis |
| Q30483303 | Defective glycinergic synaptic transmission in zebrafish motility mutants |
| Q26738425 | Defects of the Glycinergic Synapse in Zebrafish |
| Q38706633 | Deficiency of Cholesteryl Ester Transfer Protein Protects Against Atherosclerosis in Rabbits |
| Q38992859 | Derivation of stable zebrafish ES-like cells in feeder-free culture |
| Q30620310 | Developing highER-throughput zebrafish screens for in-vivo CNS drug discovery |
| Q28281488 | Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases |
| Q91697849 | Discovery of Novel Therapeutics for Muscular Dystrophies using Zebrafish Phenotypic Screens |
| Q28275277 | Distinct factors control histone variant H3.3 localization at specific genomic regions |
| Q64116989 | Diversifying the structure of zinc finger nucleases for high-precision genome editing |
| Q37363187 | Early zebrafish development: it's in the maternal genes |
| Q54597063 | Ectopic expression of cone-specific G-protein-coupled receptor kinase GRK7 in zebrafish rods leads to lower photosensitivity and altered responses. |
| Q45026864 | Editing of the Luteinizing Hormone Gene to Sterilize Channel Catfish, Ictalurus punctatus, Using a Modified Zinc Finger Nuclease Technology with Electroporation |
| Q52691670 | Efficient Gene Transfer and Gene Editing in Sterlet (Acipenser ruthenus). |
| Q33779575 | Efficient and heritable gene targeting in tilapia by CRISPR/Cas9. |
| Q47584760 | Efficient creation of an APOE knockout rabbit |
| Q36323686 | Efficient detection, quantification and enrichment of subtle allelic alterations. |
| Q37018820 | Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases. |
| Q29042244 | Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases |
| Q21089956 | Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases |
| Q35027766 | Efficient knockin mouse generation by ssDNA oligonucleotides and zinc-finger nuclease assisted homologous recombination in zygotes |
| Q46862201 | Efficient knockout of transplanted green fluorescent protein gene in medaka using TALENs. |
| Q30596307 | Efficient methods for targeted mutagenesis in zebrafish using zinc-finger nucleases: data from targeting of nine genes using CompoZr or CoDA ZFNs |
| Q34176369 | Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases. |
| Q50496238 | Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases. |
| Q24654113 | Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease |
| Q29622846 | Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases |
| Q26860518 | Emergence of zebrafish models in oncology for validating novel anticancer drug targets and nanomaterials |
| Q36252515 | Emerging applications for zebrafish as a model organism to study oxidative mechanisms and their roles in inflammation and vascular accumulation of oxidized lipids |
| Q38209315 | Emerging gene editing strategies for Duchenne muscular dystrophy targeting stem cells |
| Q37293062 | Emerging gene knockout technology in zebrafish: zinc-finger nucleases |
| Q38109520 | Emerging tools for synthetic genome design |
| Q26782747 | Enabling functional genomics with genome engineering |
| Q33886716 | Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases |
| Q55359800 | Engineering altered protein-DNA recognition specificity. |
| Q36228494 | Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases |
| Q38328602 | Engineering novel Lec1 glycosylation mutants in CHO-DUKX cells: molecular insights and effector modulation of N-acetylglucosaminyltransferase I. |
| Q38126465 | Engineering subtle targeted mutations into the mouse genome |
| Q38964283 | Enhanced gene disruption by programmable nucleases delivered by a minicircle vector |
| Q38097104 | Enhancer and gene traps for molecular imaging and genetic analysis in zebrafish |
| Q28299915 | Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures |
| Q92152766 | Evaluation and Reduction of CRISPR Off-Target Cleavage Events |
| Q34027107 | Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish |
| Q34412002 | Evaluation of OPEN zinc finger nucleases for direct gene targeting of the ROSA26 locus in mouse embryos |
| Q42130461 | Expanding CRISPR/Cas9 Genome Editing Capacity in Zebrafish Using SaCas9. |
| Q38135492 | Expanding horizons: ciliary proteins reach beyond cilia |
| Q26995224 | Expanding the scope of site-specific recombinases for genetic and metabolic engineering |
| Q37701251 | Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants. |
| Q27316307 | Expression of a Mutant kcnj2 Gene Transcript in Zebrafish |
| Q59047288 | Expression of a Mutant kcnj2 Gene Transcript in Zebrafish |
| Q36213693 | Expression of sclerostin in the developing zebrafish (Danio rerio) brain and skeleton |
| Q37365207 | Fishing for the genetic basis of cardiovascular disease. |
| Q57253689 | Fishing for understanding: Unlocking the zebrafish gene editor’s toolbox |
| Q64926601 | Fishing in the Cell Powerhouse: Zebrafish as A Tool for Exploration of Mitochondrial Defects Affecting the Nervous System. |
| Q35809888 | From phenotype to mechanism after zebrafish small molecule screens. |
| Q38827394 | GRK5-Knockout Mice Generated by TALEN-Mediated Gene Targeting |
| Q51830160 | Gene Editing in One-Cell Embryos by Zinc-Finger and TAL Nucleases. |
| Q33930132 | Gene correction by homologous recombination with zinc finger nucleases in primary cells from a mouse model of a generic recessive genetic disease |
| Q39591047 | Gene editing of human embryonic stem cells via an engineered baculoviral vector carrying zinc-finger nucleases |
| Q39417255 | Gene editing tools: state-of-the-art and the road ahead for the model and non-model fishes |
| Q38060592 | Gene knockout and knockin by zinc-finger nucleases: current status and perspectives |
| Q50463345 | Gene replacement by zinc finger nucleases in medaka embryos. |
| Q34093764 | Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases |
| Q37552793 | Gene targeting from laboratory to livestock: current status and emerging concepts. |
| Q24634563 | Gene targeting in the rat: advances and opportunities |
| Q38174163 | Gene targeting technologies in rats: zinc finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeats |
| Q39428538 | Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases |
| Q36225555 | Generating conditional mutations in zebrafish using gene-trap mutagenesis |
| Q89805532 | Generation and Characterization of a CRISPR/Cas9 -Induced 3-mst Deficient Zebrafish |
| Q36878238 | Generation and application of signaling pathway reporter lines in zebrafish |
| Q42951825 | Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning |
| Q44928029 | Generation of albino Xenopus tropicalis using zinc-finger nucleases |
| Q88733441 | Generation of genetically-engineered animals using engineered endonucleases |
| Q39506695 | Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations |
| Q28472632 | Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases |
| Q50696210 | Generation of targeted mouse mutants by embryo microinjection of TALENs. |
| Q30409021 | Genetic analysis of Xenopus tropicalis |
| Q38662564 | Genetic approaches to retinal research in zebrafish. |
| Q33699347 | Genetic model system studies of the development of the enteric nervous system, gut motility and Hirschsprung's disease |
| Q37350419 | Genetic models of cancer in zebrafish |
| Q37688945 | Genetically modified mice-successes and failures of a widely used technology |
| Q26852316 | Genetics in non-genetic model systems |
| Q26772108 | Genome Editing and Its Applications in Model Organisms |
| Q91901314 | Genome Editing with mRNA Encoding ZFN, TALEN, and Cas9 |
| Q29301748 | Genome Engineering With Zinc-Finger Nucleases |
| Q38918318 | Genome editing comes of age. |
| Q46305641 | Genome editing in fishes and their applications |
| Q46270371 | Genome editing in livestock: Are we ready for a revolution in animal breeding industry? |
| Q43179154 | Genome editing in plants via designed zinc finger nucleases |
| Q38665676 | Genome editing in zebrafish: a practical overview |
| Q34431649 | Genome editing of BmFib-H gene provides an empty Bombyx mori silk gland for a highly efficient bioreactor. |
| Q58579131 | Genome editing of oncogenes with ZFNs and TALENs: caveats in nuclease design |
| Q28290795 | Genome editing with engineered zinc finger nucleases |
| Q37999109 | Genome modifications in plant cells by custom-made restriction enzymes |
| Q39026438 | Genome-Editing Technologies: Principles and Applications |
| Q26769662 | Genome-editing Technologies for Gene and Cell Therapy |
| Q36129624 | Genome-editing technologies and their potential application in horticultural crop breeding |
| Q26800186 | Genome-editing tools for stem cell biology |
| Q36559247 | Genomic deletion induced by Tol2 transposon excision in zebrafish |
| Q44156848 | Genomic editing opens new avenues for zebrafish as a model for neurodegeneration |
| Q47327309 | Germline-specific dgcr8 knockout in zebrafish using a BACK approach. |
| Q34614125 | Global analysis of Drosophila Cys₂-His₂ zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants |
| Q33366500 | Group II intron-based gene targeting reactions in eukaryotes |
| Q37697893 | Hemostasis in Danio rerio: is the zebrafish a useful model for platelet research? |
| Q36972087 | Hepatocyte polarity |
| Q33479155 | Heritable and lineage-specific gene knockdown in zebrafish embryo |
| Q34850698 | Heritable and precise zebrafish genome editing using a CRISPR-Cas system |
| Q55054727 | Heritable gene targeting in zebrafish using customized TALENs. |
| Q34110498 | Heritable targeted inactivation of myostatin gene in yellow catfish (Pelteobagrus fulvidraco) using engineered zinc finger nucleases |
| Q46153915 | Heritable targeted inactivation of the rainbow trout (Oncorhynchus mykiss) master sex-determining gene using zinc-finger nucleases. |
| Q34794536 | High cholesterol diet induces IL-1β expression in adult but not larval zebrafish. |
| Q34755909 | High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design |
| Q33977811 | High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases |
| Q34325057 | High frequency targeted mutagenesis using engineered endonucleases and DNA-end processing enzymes |
| Q52707887 | High-Efficiency Gene Targeting in Drosophila with Zinc Finger Nucleases |
| Q36909774 | High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases. |
| Q24654686 | High-frequency modification of plant genes using engineered zinc-finger nucleases |
| Q90236873 | High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping |
| Q30407556 | High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9. |
| Q35517574 | High-throughput genome editing and phenotyping facilitated by high resolution melting curve analysis |
| Q37196274 | High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity |
| Q34504179 | Highly active zinc-finger nucleases by extended modular assembly |
| Q36228544 | Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs |
| Q43186432 | Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle |
| Q51751324 | Highly sialylated recombinant human erythropoietin production in large-scale perfusion bioreactor utilizing CHO-gmt4 (JW152) with restored GnT I function. |
| Q35153109 | Highly specific contractions of a single CAG/CTG trinucleotide repeat by TALEN in yeast. |
| Q39553858 | Homology-Independent Integration of Plasmid DNA into the Zebrafish Genome. |
| Q27024966 | Hooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era |
| Q63246437 | How mRNA therapeutics are entering the monoclonal antibody field |
| Q34124290 | Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo |
| Q41387328 | Ikk2 regulates cytokinesis during vertebrate development |
| Q37838907 | Imaging circuit formation in zebrafish |
| Q38306651 | Immune cell dynamics in the CNS: Learning from the zebrafish |
| Q34289107 | Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs). |
| Q35775664 | In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases |
| Q36065342 | In vivo chemical screening for modulators of hematopoiesis and hematological diseases |
| Q28241725 | In vivo genome editing restores haemostasis in a mouse model of haemophilia |
| Q41438039 | In vivo genome editing using a high-efficiency TALEN system |
| Q45876060 | In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency |
| Q35830212 | In vivo testing of microRNA-mediated gene knockdown in zebrafish |
| Q40427406 | Inactivation of GDP-fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR-Cas9 for production of fucose-free antibodies |
| Q36861730 | Increasing cloning possibilities using artificial zinc finger nucleases |
| Q34022968 | Integration mechanisms of transgenes and population fitness of GH transgenic fish |
| Q38284819 | Interactions of the orexin/hypocretin neurones and the histaminergic system |
| Q35241649 | Interpreting human genetic variation with in vivo zebrafish assays |
| Q37832417 | Investigating the genetics of visual processing, function and behaviour in zebrafish |
| Q37215261 | Knockout of Myostatin by Zinc-finger Nuclease in Sheep Fibroblasts and Embryos |
| Q24633888 | Knockout rats via embryo microinjection of zinc-finger nucleases |
| Q38806486 | LITTLE FISH, BIG DATA: ZEBRAFISH AS A MODEL FOR CARDIOVASCULAR AND METABOLIC DISEASE. |
| Q26995406 | Learning and memory in zebrafish larvae |
| Q37076779 | Learning to Fish with Genetics: A Primer on the Vertebrate Model Danio rerio |
| Q35131131 | Lessons from morpholino-based screening in zebrafish |
| Q35228795 | Life or death? A physiogenomic approach to understand individual variation in responses to hemorrhagic shock |
| Q39083067 | Male-sterile maize plants produced by targeted mutagenesis of the cytochrome P450-like gene (MS26) using a re-designed I-CreI homing endonuclease |
| Q30488639 | Maternal Interferon Regulatory Factor 6 is required for the differentiation of primary superficial epithelia in Danio and Xenopus embryos |
| Q91912653 | Meeting report of the OECD conference on "Genome Editing: Applications in Agriculture-Implications for Health, Environment and Regulation" |
| Q35701287 | Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy |
| Q38434192 | Methods for studying the zebrafish brain: past, present and future |
| Q34150507 | Methods for targeted mutagenesis in zebrafish using TALENs |
| Q26741958 | Methods of Genome Engineering: a New Era of Molecular Biology |
| Q50010782 | Microinjection of CRISPR/Cas9 Protein into Channel Catfish, Ictalurus punctatus, Embryos for Gene Editing. |
| Q52651990 | Minimum length of direct repeat sequences required for efficient homologous recombination induced by zinc finger nuclease in yeast. |
| Q38128482 | Mitophagy and neurodegeneration: the zebrafish model system |
| Q90412003 | Modeling Neuronal Diseases in Zebrafish in the Era of CRISPR |
| Q36066204 | Modeling disease mutations by gene targeting in one-cell mouse embryos |
| Q33703193 | Modern approaches for ultrastructural analysis of the zebrafish embryo |
| Q27664531 | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus |
| Q35054386 | Molecular psychiatry of zebrafish. |
| Q38325411 | Molecular scissors and their application in genetically modified farm animals |
| Q35036609 | Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development |
| Q58728468 | Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration |
| Q28300904 | Mutagenesis and phenotyping resources in zebrafish for studying development and human disease |
| Q39576319 | Myelopoiesis and myeloid leukaemogenesis in the zebrafish |
| Q37954778 | New insights into signaling during myelination in zebrafish |
| Q37582455 | New model systems to illuminate thyroid organogenesis. Part I: an update on the zebrafish toolbox |
| Q34998404 | New school in liver development: lessons from zebrafish |
| Q24631042 | Newer gene editing technologies toward HIV gene therapy |
| Q37482873 | NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish |
| Q46151976 | Noggin is required for first pharyngeal arch differentiation in the frog Xenopus tropicalis |
| Q38709200 | Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery |
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| Q30401043 | Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish |
| Q37672305 | Novel Genetic and Molecular Tools for the Investigation and Control of Dengue Virus Transmission by Mosquitoes |
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| Q33402786 | Novel insights into the genetic controls of primitive and definitive hematopoiesis from zebrafish models |
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| Q37989800 | On the emerging role of rabbit as human disease model and the instrumental role of novel transgenic tools. |
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| Q52644569 | Parameters and efficiency of direct gene disruption by zinc finger nucleases in medaka embryos. |
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| Q38689981 | Plant genome editing with TALEN and CRISPR. |
| Q35067240 | Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo |
| Q37194743 | Precise and heritable genome editing in evolutionarily diverse nematodes using TALENs and CRISPR/Cas9 to engineer insertions and deletions |
| Q28243268 | Precise genome modification in the crop species Zea mays using zinc-finger nucleases |
| Q41294499 | Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish |
| Q64989716 | Precision gene editing technology and applications in nephrology. |
| Q33540638 | Precision genetics for complex objectives in animal agriculture |
| Q33736344 | Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences |
| Q49916186 | Primordial germ cell-mediated transgenesis and genome editing in birds. |
| Q33696087 | Probing the DNA-binding affinity and specificity of designed zinc finger proteins |
| Q33885425 | Production of Mutated Porcine Embryos Using Zinc Finger Nucleases and a Reporter-based Cell Enrichment System |
| Q49417992 | Production of Wilson Disease Model Rabbits with Homology-Directed Precision Point Mutations in the ATP7B Gene Using the CRISPR/Cas9 System. |
| Q27011249 | Progress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseases |
| Q33559271 | Progress and prospects: techniques for site-directed mutagenesis in animal models. |
| Q24650545 | Progress and prospects: zinc-finger nucleases as gene therapy agents |
| Q44467416 | Properties of gene knockdown system by vector-based siRNA in zebrafish |
| Q28751821 | Proprietary science, open science and the role of patent disclosure: the case of zinc-finger proteins |
| Q47352700 | Protein engineering: The fate of fingers |
| Q38039493 | Protein tyrosine phosphatases in health and disease |
| Q45926089 | Protocadherin-19 is essential for early steps in brain morphogenesis. |
| Q43240978 | Rapid and highly efficient construction of TALE-based transcriptional regulators and nucleases for genome modification |
| Q30493523 | Rapid behavior-based identification of neuroactive small molecules in the zebrafish |
| Q64077710 | Rapid habituation of a touch-induced escape response in Zebrafish (Danio rerio) Larvae |
| Q33406501 | Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN). |
| Q58780870 | Rare Genetic Blood Disease Modeling in Zebrafish |
| Q37795947 | Rat traps: filling the toolbox for manipulating the rat genome |
| Q39680707 | Re-programming DNA-binding specificity in zinc finger proteins for targeting unique address in a genome. |
| Q38531847 | Recent developments and clinical studies utilizing engineered zinc finger nuclease technology. |
| Q38157100 | Recent progress in genome engineering techniques in the silkworm, Bombyx mori. |
| Q26861563 | Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond |
| Q26744279 | Regeneration of Zebrafish CNS: Adult Neurogenesis |
| Q89940610 | Regeneration of the central nervous system-principles from brain regeneration in adult zebrafish |
| Q37424994 | Removal of the bloom syndrome DNA helicase extends the utility of imprecise transposon excision for making null mutations in Drosophila |
| Q28245039 | Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection |
| Q35806361 | Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish. |
| Q33974209 | Reverse genetics in zebrafish by TILLING. |
| Q38848999 | Screening of mRNA Chemical Modification to Maximize Protein Expression with Reduced Immunogenicity. |
| Q34154630 | Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA) |
| Q34110518 | Selection-independent generation of gene knockout mouse embryonic stem cells using zinc-finger nucleases |
| Q30401800 | Sensory hair cell regeneration in the zebrafish lateral line |
| Q34496614 | Silencer-delimited transgenesis: NRSE/RE1 sequences promote neural-specific transgene expression in a NRSF/REST-dependent manner. |
| Q34390580 | Simple methods for generating and detecting locus-specific mutations induced with TALENs in the zebrafish genome |
| Q37481066 | Simple vertebrate models for chemical genetics and drug discovery screens: lessons from zebrafish and Xenopus. |
| Q34760684 | Simultaneous screening and validation of effective zinc finger nucleases in yeast |
| Q26749033 | Site-Specific Integration of Exogenous Genes Using Genome Editing Technologies in Zebrafish |
| Q29029547 | Site-directed mutagenesis in Arabidopsis using custom-designed zinc finger nucleases |
| Q41455914 | Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases |
| Q34029188 | Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads |
| Q34568279 | Stability of zinc finger nuclease protein is enhanced by the proteasome inhibitor MG132. |
| Q36709900 | Stable gene silencing in zebrafish with spatiotemporally targetable RNA interference |
| Q36314622 | Stressing zebrafish for behavioral genetics |
| Q36321605 | Study of pluripotency markers in zebrafish embryos and transient embryonic stem cell cultures |
| Q38658928 | Studying Autophagy in Zebrafish. |
| Q40654970 | Synthetic mRNA: Production, Introduction into Cells, and Physiological Consequences |
| Q39335486 | Synthetic nucleases for genome engineering in plants: prospects for a bright future |
| Q37202609 | SysZNF: the C2H2 zinc finger gene database |
| Q91930979 | Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9 |
| Q37557135 | Systematizing serendipity for cardiovascular drug discovery |
| Q43775785 | TALEN-mediated precise genome modification by homologous recombination in zebrafish. |
| Q36540717 | TALENs: a widely applicable technology for targeted genome editing |
| Q36017209 | Targeted Mutagenesis in Plant Cells through Transformation of Sequence-Specific Nuclease mRNA. |
| Q24653591 | Targeted chromosomal deletions in human cells using zinc finger nucleases |
| Q50496178 | Targeted disruption of exogenous EGFP gene in medaka using zinc-finger nucleases. |
| Q50469532 | Targeted disruption of the sheep MSTN gene by engineered zinc-finger nucleases. |
| Q29308378 | Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme |
| Q42862072 | Targeted gene disruption in somatic zebrafish cells using engineered TALENs |
| Q36179350 | Targeted gene knockout by direct delivery of zinc-finger nuclease proteins |
| Q28241553 | Targeted genome editing across species using ZFNs and TALENs |
| Q37718373 | Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases |
| Q24655166 | Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly |
| Q64386982 | Targeted genome editing in pluripotent stem cells using zinc-finger nucleases |
| Q35149230 | Targeted genome engineering via zinc finger nucleases |
| Q34196443 | Targeted genome modification in mice using zinc-finger nucleases |
| Q28300670 | Targeted integration in rat and mouse embryos with zinc-finger nucleases |
| Q37349104 | Targeted manipulation of mammalian genomes using designed zinc finger nucleases |
| Q34257396 | Targeted mutagenesis in Atlantic salmon (Salmo salar L.) using the CRISPR/Cas9 system induces complete knockout individuals in the F0 generation |
| Q51139534 | Targeted mutagenesis in sea urchin embryos using TALENs. |
| Q39977246 | Targeted mutagenesis in the progeny of maize transgenic plants |
| Q43227935 | Targeted mutagenesis in zebrafish |
| Q42926067 | Targeted mutagenesis in zebrafish using customized zinc-finger nucleases |
| Q34748828 | Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus). |
| Q37935723 | Targeted mutagenesis of zebrafish: use of zinc finger nucleases |
| Q51270120 | Targeted mutagenesis using zinc-finger nucleases in perennial fruit trees. |
| Q35445369 | Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates |
| Q28305200 | Targeted transgene integration in plant cells using designed zinc finger nucleases |
| Q24599859 | Targeting DNA With Fingers and TALENs |
| Q27974482 | Targeting Plasmodium PI(4)K to eliminate malaria |
| Q82102673 | Techniques for optimizing the creation of mutations in zebrafish using N-ethyl-N-nitrosourea |
| Q28474883 | Temporally-controlled site-specific recombination in zebrafish |
| Q38608686 | The Power of Zebrafish in Personalised Medicine. |
| Q39160939 | The Role of Gene Editing in Neurodegenerative Diseases |
| Q55709239 | The Role of Gene Editing in Neurodegenerative Diseases. |
| Q37393740 | The Tol2-mediated Gal4-UAS method for gene and enhancer trapping in zebrafish |
| Q38831316 | The Toolbox for Conditional Zebrafish Cancer Models. |
| Q28658542 | The Zebrafish GenomeWiki: a crowdsourcing approach to connect the long tail for zebrafish gene annotation |
| Q35917118 | The challenges of implementing pathogen control strategies for fishes used in biomedical research |
| Q38985822 | The combinational use of CRISPR/Cas9-based gene editing and targeted toxin technology enables efficient biallelic knockout of the α-1,3-galactosyltransferase gene in porcine embryonic fibroblasts |
| Q37755505 | The discovery of zinc fingers and their development for practical applications in gene regulation and genome manipulation |
| Q89595669 | The gonadotropin-releasing hormones: Lessons from fish |
| Q37417898 | The power of the zebrafish for disease analysis |
| Q42745255 | The world according to zebrafish: how neural circuits generate behavior |
| Q37266220 | The zebrafish as a model for complex tissue regeneration |
| Q37659191 | The zebrafish model system in cardiovascular research: A tiny fish with mighty prospects |
| Q38839128 | Tissue-specific gene targeting using CRISPR/Cas9. |
| Q38788714 | To CRISPR and beyond: the evolution of genome editing in stem cells |
| Q56057560 | Tools for translation: non-viral materials for therapeutic mRNA delivery |
| Q35176354 | Toward a better understanding of human eye disease insights from the zebrafish, Danio rerio. |
| Q37884001 | Toward molecular genetic dissection of neural circuits for emotional and motivational behaviors |
| Q37948867 | Towards artificial metallonucleases for gene therapy: recent advances and new perspectives |
| Q47761069 | Trait stacking via targeted genome editing. |
| Q45142353 | Transient cold shock enhances zinc-finger nuclease-mediated gene disruption. |
| Q42019037 | Tumor-specific signaling to p53 is mimicked by Mdm2 inactivation in zebrafish: insights from mdm2 and mdm4 mutant zebrafish |
| Q42102618 | Unsuccessful attempt at gene-editing by homologous recombination in the zebrafish germ line using the approach of "Rong and Golic". |
| Q35017855 | Use of RecA fusion proteins to induce genomic modifications in zebrafish |
| Q37189999 | Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo |
| Q39355528 | Use of zinc finger nuclease technology to knock out efflux transporters in C2BBe1 cells. |
| Q50431170 | Using Zebrafish to Test the Genetic Basis of Human Craniofacial Diseases. |
| Q37777386 | Using Zinc Finger Nucleases for Efficient and Heritable Gene Disruption in Zebrafish |
| Q36619859 | Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases |
| Q39244796 | Using engineered endonucleases to create knockout and knockin zebrafish models |
| Q35094539 | Using the zebrafish lateral line to uncover novel mechanisms of action and prevention in drug-induced hair cell death |
| Q38691398 | Using zebrafish as a model to study the role of epigenetics in hearing loss |
| Q37354305 | Using zebrafish to assess the impact of drugs on neural development and function |
| Q90543376 | Versatile Genome Engineering Techniques Advance Human Ocular Disease Researches in Zebrafish |
| Q35823895 | Versatile and efficient genome editing in human cells by combining zinc-finger nucleases with adeno-associated viral vectors. |
| Q36360163 | ZEBRAFISH AS AN IN VIVO MODEL FOR SUSTAINABLE CHEMICAL DESIGN. |
| Q29615505 | ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering |
| Q33806411 | ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms. |
| Q34047654 | Zebrafish Genome Engineering Using the CRISPR-Cas9 System. |
| Q30393797 | Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein. |
| Q28078210 | Zebrafish Models of Human Leukemia: Technological Advances and Mechanistic Insights |
| Q57166914 | Zebrafish Models of Neurodevelopmental Disorders: Past, Present, and Future |
| Q35463427 | Zebrafish antipredatory responses: a future for translational research? |
| Q33584755 | Zebrafish as a model for cancer self-renewal |
| Q35070710 | Zebrafish as a model for normal and malignant hematopoiesis |
| Q38140444 | Zebrafish as a model system for mitochondrial biology and diseases |
| Q38131275 | Zebrafish as a model to study PTPs during development |
| Q37831557 | Zebrafish as a model to understand autophagy and its role in neurological disease |
| Q36947906 | Zebrafish churchill regulates developmental gene expression and cell migration |
| Q36894189 | Zebrafish models for ectopic mineralization disorders: practical issues from morpholino design to post-injection observations |
| Q45734117 | Zebrafish models for human cancer |
| Q38198431 | Zebrafish models of cancer: progress and future challenges |
| Q37889227 | Zebrafish models to study hypoxia-induced pathological angiogenesis in malignant and nonmalignant diseases. |
| Q38088821 | Zebrafish muscular disease models towards drug discovery |
| Q58567978 | Zebrafish research: Rewriting the rulebook |
| Q36242764 | Zebrafish rest regulates developmental gene expression but not neurogenesis |
| Q36072567 | Zebrafish thrombocytes: functions and origins |
| Q38414520 | Zebrafish xenotransplantation as a tool for in vivo cancer study |
| Q60043617 | Zebrafish: Development of a Vertebrate Model Organism |
| Q37387341 | Zebrafish: a model for the study of addiction genetics |
| Q37714977 | Zebrafish: a model system to examine the neurodevelopmental basis of schizophrenia |
| Q33957629 | ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool |
| Q37241457 | Zinc Finger Nucleases: Tailor-made for Gene Therapy |
| Q37415654 | Zinc finger nuclease knock-out of NADPH:cytochrome P450 oxidoreductase (POR) in human tumor cell lines demonstrates that hypoxia-activated prodrugs differ in POR dependence |
| Q39168458 | Zinc finger nuclease: a new approach for excising HIV-1 proviral DNA from infected human T cells |
| Q33622931 | Zinc finger nucleases as tools to understand and treat human diseases |
| Q24603161 | Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases |
| Q24604726 | Zinc finger-based knockout punches for zebrafish genes |
| Q36079444 | Zinc-finger nuclease-mediated targeted insertion of reporter genes for quantitative imaging of gene expression in sea urchin embryos. |
| Q35174917 | Zinc-finger nucleases for somatic gene therapy: the next frontier |
| Q37612948 | Zinc-finger nucleases: a powerful tool for genetic engineering of animals |
| Q37771055 | Zinc-finger nucleases: new strategies to target the rat genome |
| Q37148527 | Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells |
| Q26741950 | mRNA-Based Therapeutics - Advances and Perspectives |
| Q38252360 | mRNA-based therapeutics--developing a new class of drugs |
| Q33939746 | p53 Gene repair with zinc finger nucleases optimised by yeast 1-hybrid and validated by Solexa sequencing |
| Q28488259 | p53 gene targeting by homologous recombination in fish ES cells |
| Q37609161 | ΦC31 integrase mediates efficient cassette exchange in the zebrafish germline |
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