| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1035094532 |
| P356 | DOI | 10.1038/NPROT.2009.98 |
| P932 | PMC publication ID | 2858690 |
| P698 | PubMed publication ID | 19798082 |
| P5875 | ResearchGate publication ID | 26864451 |
| P50 | author | J. Keith Joung | Q28033740 |
| P2093 | author name string | Daniel F Voytas | |
| Jeffry D Sander | |||
| Morgan L Maeder | |||
| Stacey Thibodeau-Beganny | |||
| P2860 | cites work | In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase. | Q46025403 |
| Validated zinc finger protein designs for all 16 GNN DNA triplet targets | Q46443445 | ||
| Protein engineering: The fate of fingers | Q47352700 | ||
| High-throughput beta-galactosidase assay for bacterial cell-based reporter systems | Q47901402 | ||
| Evolution of programmable zinc finger-recombinases with activity in human cells. | Q51067699 | ||
| High-frequency homologous recombination in plants mediated by zinc-finger nucleases. | Q51327085 | ||
| Custom zinc-finger nucleases for use in human cells. | Q51391970 | ||
| Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code | Q56896662 | ||
| Site-specific cleavage of DNA–RNA hybrids by zinc finger/FokI cleavage domain fusions | Q58375256 | ||
| Controlling gene expression in plants using synthetic zinc finger transcription factors | Q78691900 | ||
| Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells | Q24535831 | ||
| Genetic analysis of prokaryotic and eukaryotic DNA-binding proteins in Escherichia coli | Q24548197 | ||
| Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain | Q24567623 | ||
| Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks | Q24645403 | ||
| Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases | Q24647647 | ||
| Positive and negative regulation of endogenous genes by designed transcription factors | Q24649843 | ||
| Progress and prospects: zinc-finger nucleases as gene therapy agents | Q24650545 | ||
| Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification | Q24651280 | ||
| Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases | Q24652815 | ||
| High-frequency modification of plant genes using engineered zinc-finger nucleases | Q24654686 | ||
| Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases | Q24680179 | ||
| A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions | Q24681782 | ||
| Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection | Q24683209 | ||
| Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes | Q27635218 | ||
| Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions | Q27733960 | ||
| Enhancing Gene Targeting with Designed Zinc Finger Nucleases | Q28202461 | ||
| Engineering polydactyl zinc-finger transcription factors | Q28217078 | ||
| Highly efficient endogenous human gene correction using designed zinc-finger nucleases | Q28243157 | ||
| Precise genome modification in the crop species Zea mays using zinc-finger nucleases | Q28243268 | ||
| Gene targeting using zinc finger nucleases | Q28265983 | ||
| Unexpected failure rates for modular assembly of engineered zinc fingers | Q28278303 | ||
| Zinc-finger nucleases: the next generation emerges | Q28283445 | ||
| Targeted transgene integration in plant cells using designed zinc finger nucleases | Q28305200 | ||
| An improved zinc-finger nuclease architecture for highly specific genome editing | Q28307951 | ||
| Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases | Q28307957 | ||
| Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery | Q29014419 | ||
| Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases | Q29615069 | ||
| Chimeric nucleases stimulate gene targeting in human cells | Q29615384 | ||
| Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins | Q30699677 | ||
| Scanning the human genome with combinatorial transcription factor libraries. | Q30887293 | ||
| Human zinc fingers as building blocks in the construction of artificial transcription factors. | Q30887297 | ||
| Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers | Q32028923 | ||
| Genetic reprogramming of tumor cells by zinc finger transcription factors | Q33221141 | ||
| Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly. | Q33280963 | ||
| Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool. | Q33285803 | ||
| Engineering Cys2His2 zinc finger domains using a bacterial cell-based two-hybrid selection system | Q33322077 | ||
| Modulation of drug resistance by artificial transcription factors. | Q33322421 | ||
| Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN). | Q33406501 | ||
| Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains | Q33786657 | ||
| Targeted mutagenesis using zinc-finger nucleases in Arabidopsis | Q33836378 | ||
| Stimulation of homologous recombination through targeted cleavage by chimeric nucleases | Q33927812 | ||
| Custom-designed zinc finger nucleases: what is next? | Q34067230 | ||
| Regulation of transgene expression in plants with polydactyl zinc finger transcription factors | Q34192580 | ||
| Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors | Q34192593 | ||
| Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage | Q34222841 | ||
| Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells | Q34353549 | ||
| Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site | Q34434986 | ||
| Design, engineering, and characterization of zinc finger nucleases | Q34559924 | ||
| Efficient gene targeting in Drosophila with zinc-finger nucleases | Q34588397 | ||
| Critical parameters for genome editing using zinc finger nucleases | Q34592886 | ||
| Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases | Q34615432 | ||
| Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells | Q35133826 | ||
| Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases | Q35645641 | ||
| Synergy between adjacent zinc fingers in sequence-specific DNA recognition | Q36152818 | ||
| Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity. | Q36347830 | ||
| Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases. | Q36545930 | ||
| Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases. | Q37018820 | ||
| Synthesis of programmable integrases | Q37126112 | ||
| Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc-finger arrays | Q37202413 | ||
| The use of zinc finger peptides to study the role of specific factor binding sites in the chromatin environment. | Q38288344 | ||
| Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins | Q38357603 | ||
| Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene | Q38473641 | ||
| Expanding or restricting the target site repertoire of zinc-finger nucleases: the inter-domain linker as a major determinant of target site selectivity | Q39500874 | ||
| Comparison of zinc finger nucleases for use in gene targeting in mammalian cells | Q40003411 | ||
| DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases | Q40047890 | ||
| Mammalian gene targeting with designed zinc finger nucleases | Q40371944 | ||
| Activation of vascular endothelial growth factor A transcription in tumorigenic glioblastoma cell lines by an enhancer with cell type-specific DNase I accessibility | Q40742581 | ||
| Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A. | Q40832375 | ||
| Induction of angiogenesis in a mouse model using engineered transcription factors | Q42808653 | ||
| P433 | issue | 10 | |
| P921 | main subject | open-source software | Q1130645 |
| P304 | page(s) | 1471-1501 | |
| P577 | publication date | 2009-09-17 | |
| P1433 | published in | Nature Protocols | Q3337109 |
| P1476 | title | Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays | |
| P478 | volume | 4 |
| Q34292208 | A synthetic biology framework for programming eukaryotic transcription functions. |
| Q34244995 | A transcription activator-like effector toolbox for genome engineering |
| Q36268744 | An ensemble micro neural network approach for elucidating interactions between zinc finger proteins and their target DNA |
| Q37734422 | An improved predictive recognition model for Cys(2)-His(2) zinc finger proteins |
| Q38831318 | Approaches to Inactivate Genes in Zebrafish |
| Q45872160 | Benzoate X receptor zinc-finger gene switches for drug-inducible regulation of transcription. |
| Q38588821 | CRISPR-Cas: From the Bacterial Adaptive Immune System to a Versatile Tool for Genome Engineering |
| Q41755483 | CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox |
| Q37950979 | Cell Biology Symposium: Zinc finger nucleases to create custom-designed modifications in the swine (Sus scrofa) genome. |
| Q46626607 | Cloning and evaluation of different constitutive promoters in the oleaginous yeast Rhodosporidium toruloides |
| Q37213389 | Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila |
| Q34476881 | Completion of the swine genome will simplify the production of swine as a large animal biomedical model |
| Q42859214 | Context dependence between subdomains in the DNA binding interface of the I-CreI homing endonuclease |
| Q42132395 | Correction of the ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Zinc-Finger Nuclease Homology-Directed Repair |
| Q30537830 | Coupling endonucleases with DNA end-processing enzymes to drive gene disruption |
| Q36832214 | Design and Development of Artificial Zinc Finger Transcription Factors and Zinc Finger Nucleases to the hTERT Locus |
| Q26787105 | Designed nucleases for targeted genome editing |
| Q38669948 | Developmental history and application of CRISPR in human disease |
| Q37042113 | Editing the epigenome: technologies for programmable transcription and epigenetic modulation |
| Q34350238 | Efficient CRISPR-Cas9-mediated genome editing in Plasmodium falciparum. |
| Q24605428 | Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription |
| Q40403124 | Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells |
| Q30596307 | Efficient methods for targeted mutagenesis in zebrafish using zinc-finger nucleases: data from targeting of nine genes using CompoZr or CoDA ZFNs |
| Q47684229 | Engineered Zinc Finger DNA-Binding Domains: Synthesis, Assessment of DNA-Binding Affinity, and Direct Protein Delivery to Mammalian Cells |
| Q34257442 | Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects |
| Q41600298 | Engineering and Application of Zinc Finger Proteins and TALEs for Biomedical Research |
| Q42209309 | Engineering designer nucleases with customized cleavage specificities |
| Q34425833 | Engineering designer transcription activator-like effector nucleases (TALENs) by REAL or REAL-Fast assembly |
| Q34412002 | Evaluation of OPEN zinc finger nucleases for direct gene targeting of the ROSA26 locus in mouse embryos |
| Q36832219 | Expanding the Repertoire of Target Sites for Zinc Finger Nuclease-mediated Genome Modification |
| Q38255828 | Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9. |
| Q36268716 | Exploiting the recognition code for elucidating the mechanism of zinc finger protein-DNA interactions |
| Q30400051 | Extensive protein and DNA backbone sampling improves structure-based specificity prediction for C2H2 zinc fingers. |
| Q35773798 | From DNA to targeted therapeutics: bringing synthetic biology to the clinic |
| Q51830160 | Gene Editing in One-Cell Embryos by Zinc-Finger and TAL Nucleases. |
| Q38846192 | Gene editing and its application for hematological diseases |
| Q37763190 | Generation and genetic modification of induced pluripotent stem cells |
| Q50696210 | Generation of targeted mouse mutants by embryo microinjection of TALENs. |
| Q34982862 | Genetic therapies for cystic fibrosis lung disease |
| Q38665676 | Genome editing in zebrafish: a practical overview |
| Q38113338 | Genome editing of human pluripotent stem cells to generate human cellular disease models |
| Q58579131 | Genome editing of oncogenes with ZFNs and TALENs: caveats in nuclease design |
| Q38716194 | Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis |
| Q39239599 | Genome editing: a robust technology for human stem cells |
| Q38842828 | Genome engineering tools for building cellular models of disease |
| Q38253811 | Genome engineering via TALENs and CRISPR/Cas9 systems: challenges and perspectives |
| Q37999109 | Genome modifications in plant cells by custom-made restriction enzymes |
| Q22122302 | Genome-scale engineering for systems and synthetic biology |
| Q33977811 | High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases |
| Q37692030 | How to Train a Cell-Cutting-Edge Molecular Tools |
| Q34289107 | Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs). |
| Q35775664 | In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases |
| Q49703597 | Innovative approaches to genome editing in avian species. |
| Q37181366 | Integrase-defective lentiviral vectors as a delivery platform for targeted modification of adenosine deaminase locus |
| Q42265729 | Is BAC transgenesis obsolete? State of the art in the era of designer nucleases |
| Q34167797 | Modular extracellular sensor architecture for engineering mammalian cell-based devices |
| Q35088938 | Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells |
| Q39576319 | Myelopoiesis and myeloid leukaemogenesis in the zebrafish |
| Q52663398 | Neuroepigenetic Editing. |
| Q38519892 | Novel Genome-Editing Tools to Model and Correct Primary Immunodeficiencies. |
| Q50488180 | Nuclear gene targeting in Chlamydomonas using engineered zinc-finger nucleases. |
| Q38175498 | Nuclease-mediated genome editing: At the front-line of functional genomics technology |
| Q39018926 | Nuclease-stimulated homologous recombination at the human β-globin gene |
| Q38214809 | Precision genome editing: a small revolution for glycobiology. |
| Q27011249 | Progress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseases |
| Q38531847 | Recent developments and clinical studies utilizing engineered zinc finger nuclease technology. |
| Q37659896 | Redesign of extensive protein-DNA interfaces of meganucleases using iterative cycles of in vitro compartmentalization |
| Q38325156 | Redesigning the single-chain variant of the restriction endonuclease PvuII by circular permutation. |
| Q36298666 | Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains |
| Q48925635 | Seamless genome editing in human pluripotent stem cells using custom endonuclease-based gene targeting and the piggyBac transposon. |
| Q34154630 | Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA) |
| Q34110518 | Selection-independent generation of gene knockout mouse embryonic stem cells using zinc-finger nucleases |
| Q41875772 | Selective DNA demethylation by fusion of TDG with a sequence-specific DNA-binding domain |
| Q34760684 | Simultaneous screening and validation of effective zinc finger nucleases in yeast |
| Q21559671 | Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes |
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| Q36405518 | Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs |
| Q26782876 | Strategies for precision modulation of gene expression by epigenome editing: an overview |
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| Q52770186 | TALEN-mediated Drosophila genome editing: protocols and applications. |
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