In vivo chemical screening for modulators of hematopoiesis and hematological diseases

scientific article

In vivo chemical screening for modulators of hematopoiesis and hematological diseases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2012/851674
P932PMC publication ID3385708
P698PubMed publication ID22778745
P5875ResearchGate publication ID229017348

P2093author name stringJ-R Joanna Yeh
Yiyun Zhang
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How were new medicines discovered?Q29616641
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Erythroid inhibition by the leukemic fusion AML1-ETO is associated with impaired acetylation of the major erythroid transcription factor GATA-1.Q30439786
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Young thrombocytes initiate the formation of arterial thrombi in zebrafishQ30479622
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T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation.Q34412894
Hematopoietic stem cell fate is established by the Notch-Runx pathwayQ34451310
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Small zebrafish in a big chemical pond.Q35951647
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Use of the zebrafish system to study primitive and definitive hematopoiesisQ36312218
AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiencyQ36371457
Beta-catenin is dispensable for hematopoiesis and lymphopoiesisQ36399011
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivoQ36488720
Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantationQ36508850
A practical view of 'druggability'.Q36524844
Definitive hematopoietic stem/progenitor cells manifest distinct differentiation output in the zebrafish VDA and PBI.Q37106412
Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferationQ37209033
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Hematopoietic stem cell development is dependent on blood flow.Q37294702
Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryoQ37327026
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasisQ37416219
Hematopoietic cell development in the zebrafish embryoQ37505960
Systematizing serendipity for cardiovascular drug discoveryQ37557135
Experimental basis of cord blood transplantationQ37607981
Zebrafish tumor assays: the state of transplantationQ37667075
Cellular dissection of zebrafish hematopoiesisQ37873092
Laser-induced thrombosis in zebrafishQ37873097
Engineering zinc finger nucleases for targeted mutagenesis of zebrafishQ37933553
Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemiaQ38287713
Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.Q38290513
AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.Q38302335
COX2 overexpression is a prognostic marker for Stage III breast cancerQ38474547
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjecthemopoiesisQ919283
P304page(s)851674
P577publication date2012-06-19
P1433published inAdvances in HematologyQ26842580
P1476titleIn vivo chemical screening for modulators of hematopoiesis and hematological diseases
P478volume2012

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cites work (P2860)
Q35934157Danio rerio: Small Fish Making a Big Splash in Leukemia
Q58780870Rare Genetic Blood Disease Modeling in Zebrafish
Q38951357Understanding the regulation of vertebrate hematopoiesis and blood disorders - big lessons from a small fish

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