Cysteinyl leukotrienes and their receptors; emerging concepts

scientific article (publication date: July 2014)

Cysteinyl leukotrienes and their receptors; emerging concepts is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4168/AAIR.2014.6.4.288
P3181OpenCitations bibliographic resource ID287900
P932PMC publication ID4077954
P698PubMed publication ID24991451
P5875ResearchGate publication ID263746072

P2093author name stringYoshihide Kanaoka
Joshua A Boyce
P2860cites workCharacterization of the human cysteinyl leukotriene CysLT1 receptorQ22010199
Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4Q24564369
Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthmaQ24564777
Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytesQ24633568
Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptorsQ24646354
Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptorQ24647514
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptorQ24672638
Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trialQ28192038
Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitisQ28194143
Expression of 5-lipoxygenase and cyclooxygenase pathway enzymes in nasal polyps of patients with aspirin-intolerant asthmaQ28196323
CysLT1 receptor upregulation by TGF-β and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4Q28203816
Effect of leukotriene modifier drugs on the safety of oral aspirin challengesQ28212449
Expression of the cysteinyl leukotriene receptors cysLT(1) and cysLT(2) in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitisQ28217469
Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils.Q44072149
Effects of montelukast and beclomethasone on airway function and asthma controlQ44237810
Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjectsQ44241228
Expression of cysteinyl leukotriene synthetic and signalling proteins in inflammatory cells in active seasonal allergic rhinitisQ44602473
Human T(H)2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1.Q44891908
Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthmaQ46363432
Identification of endogenous surrogate ligands for human P2Y12 receptors by in silico and in vitro methodsQ46721760
CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation.Q46818525
Agonist- and T(H)2 cytokine-induced up-regulation of cysteinyl leukotriene receptor messenger RNA in human monocytesQ46946616
Reduced expression of the prostaglandin E2 receptor E-prostanoid 2 on bronchial mucosal leukocytes in patients with aspirin-sensitive asthmaQ48020876
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cellsQ57920567
Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skinQ67257989
Recovery of Leukotriene E4from the Urine of Patients with Airway ObstructionQ67491764
Urinary Leukotriene E4Concentrations Increase after Aspirin Challenge in Aspirin-sensitive Asthmatic SubjectsQ67915846
Transcellular biosynthesis of sulfidopeptide leukotrienes during receptor-mediated stimulation of human neutrophil/platelet mixturesQ68578025
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptorsQ28261556
Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligandQ28287399
Regulation of cysteinyl leukotriene type 1 receptor internalization and signalingQ28297665
The mechanism of LTE4-induced histamine hyperresponsiveness in guinea-pig tracheal and human bronchial smooth muscle, in vitroQ28322346
The type 1 cysteinyl leukotriene receptor triggers calcium influx and chemotaxis in mouse alpha beta- and gamma delta effector T cellsQ28509514
GPR17 regulates immune pulmonary inflammation induced by house dust mitesQ28512834
Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2Q28585904
Innate lymphoid cells--a proposal for uniform nomenclatureQ29617431
Characterization of the human cysteinyl leukotriene 2 receptorQ30305734
Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammationQ33356884
Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937.Q33826817
Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonistQ33964630
Enhanced leukotriene synthesis in leukocytes of atopic and asthmatic subjectsQ34402988
CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cellsQ34662206
Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienesQ34681509
Increase in urinary leukotriene LTE4 levels in acute asthma: correlation with airflow limitationQ35536504
Cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammationQ36339008
Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblastsQ36353710
T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4.Q36376120
Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cellsQ36929692
Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine productionQ36991150
Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17.Q37193227
Prostaglandin E2 deficiency causes a phenotype of aspirin sensitivity that depends on platelets and cysteinyl leukotrienesQ37240446
GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.Q37261678
Leukotriene E4-induced airway hyperresponsiveness of guinea pig tracheal smooth muscle to histamine and evidence for three separate sulfidopeptide leukotriene receptorsQ37562061
Pathogenesis of aspirin-exacerbated respiratory disease and reactionsQ38103710
A randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthmaQ39290977
Functional expression of cysteinyl leukotriene receptors on human plateletsQ39708804
A role for inflammatory mediators in heterologous desensitization of CysLT1 receptor in human monocytes.Q39766422
Genome-wide methylation profile of nasal polyps: relation to aspirin hypersensitivity in asthmaticsQ39811129
Correlation between expression of 5-lipoxygenase-activating protein, 5-lipoxygenase, and cellular leukotriene synthesisQ41714750
Cutting edge: Leukotriene C4 activates mouse platelets in plasma exclusively through the type 2 cysteinyl leukotriene receptorQ42153378
Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthmaQ42745189
Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase.Q42809059
Attenuated zymosan-induced peritoneal vascular permeability and IgE-dependent passive cutaneous anaphylaxis in mice lacking leukotriene C4 synthaseQ43586333
IL-13 and IL-4 up-regulate cysteinyl leukotriene 1 receptor expression in human monocytes and macrophagesQ43710176
Inhaled leukotriene E(4), but not leukotriene D(4), increased airway inflammatory cells in subjects with atopic asthmaQ43796672
Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responsesQ43946818
Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthmaQ69352841
Comparative contractile responses to sulfidopeptide leukotrienes in normal and asthmatic human subjectsQ69829869
Bronchoconstrictor effects of leukotriene C in humansQ70298182
Comparative bronchoconstrictor effects of histamine, leukotriene C, and leukotriene D in normal human volunteersQ70629252
Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: a 6-month randomized multicenter trial. Zileuton Study GroupQ71823499
Expression of LTC4 synthase during the development of eosinophils in vitro from cord blood progenitorsQ71834809
Activation of protein kinase C down-regulates leukotriene C4 synthase activity and attenuates cysteinyl leukotriene production in an eosinophilic substrain of HL-60 cellsQ72037718
Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjectsQ72252746
Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthmaQ72352958
The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthmaQ72605042
Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: a randomized, placebo-controlled clinical trialQ73784748
Cromolyn sodium prevents bronchoconstriction and urinary LTE4 excretion in aspirin-induced asthmaQ74289995
Characteristics of leukotriene biosynthesis by human granulocytes in presence of plasmaQ74345295
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmaticsQ74490010
Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjectsQ77178375
IL-5 increases expression of 5-lipoxygenase-activating protein and translocates 5-lipoxygenase to the nucleus in human blood eosinophilsQ77929292
Cyclooxygenase-2 mRNA is downexpressed in nasal polyps from aspirin-sensitive asthmaticsQ77950275
Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammationQ80967764
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)288-95
P577publication date2014-07-01
P1433published inAllergy, Asthma & Immunology ResearchQ13429052
P1476titleCysteinyl leukotrienes and their receptors; emerging concepts
P478volume6

Reverse relations

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