scholarly article | Q13442814 |
P2093 | author name string | Yoshihide Kanaoka | |
Joshua A Boyce | |||
P2860 | cites work | Characterization of the human cysteinyl leukotriene CysLT1 receptor | Q22010199 |
Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4 | Q24564369 | ||
Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma | Q24564777 | ||
Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes | Q24633568 | ||
Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors | Q24646354 | ||
Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor | Q24647514 | ||
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor | Q24672638 | ||
Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial | Q28192038 | ||
Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis | Q28194143 | ||
Expression of 5-lipoxygenase and cyclooxygenase pathway enzymes in nasal polyps of patients with aspirin-intolerant asthma | Q28196323 | ||
CysLT1 receptor upregulation by TGF-β and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4 | Q28203816 | ||
Effect of leukotriene modifier drugs on the safety of oral aspirin challenges | Q28212449 | ||
Expression of the cysteinyl leukotriene receptors cysLT(1) and cysLT(2) in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis | Q28217469 | ||
Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils. | Q44072149 | ||
Effects of montelukast and beclomethasone on airway function and asthma control | Q44237810 | ||
Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects | Q44241228 | ||
Expression of cysteinyl leukotriene synthetic and signalling proteins in inflammatory cells in active seasonal allergic rhinitis | Q44602473 | ||
Human T(H)2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1. | Q44891908 | ||
Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthma | Q46363432 | ||
Identification of endogenous surrogate ligands for human P2Y12 receptors by in silico and in vitro methods | Q46721760 | ||
CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation. | Q46818525 | ||
Agonist- and T(H)2 cytokine-induced up-regulation of cysteinyl leukotriene receptor messenger RNA in human monocytes | Q46946616 | ||
Reduced expression of the prostaglandin E2 receptor E-prostanoid 2 on bronchial mucosal leukocytes in patients with aspirin-sensitive asthma | Q48020876 | ||
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells | Q57920567 | ||
Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin | Q67257989 | ||
Recovery of Leukotriene E4from the Urine of Patients with Airway Obstruction | Q67491764 | ||
Urinary Leukotriene E4Concentrations Increase after Aspirin Challenge in Aspirin-sensitive Asthmatic Subjects | Q67915846 | ||
Transcellular biosynthesis of sulfidopeptide leukotrienes during receptor-mediated stimulation of human neutrophil/platelet mixtures | Q68578025 | ||
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors | Q28261556 | ||
Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand | Q28287399 | ||
Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling | Q28297665 | ||
The mechanism of LTE4-induced histamine hyperresponsiveness in guinea-pig tracheal and human bronchial smooth muscle, in vitro | Q28322346 | ||
The type 1 cysteinyl leukotriene receptor triggers calcium influx and chemotaxis in mouse alpha beta- and gamma delta effector T cells | Q28509514 | ||
GPR17 regulates immune pulmonary inflammation induced by house dust mites | Q28512834 | ||
Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2 | Q28585904 | ||
Innate lymphoid cells--a proposal for uniform nomenclature | Q29617431 | ||
Characterization of the human cysteinyl leukotriene 2 receptor | Q30305734 | ||
Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammation | Q33356884 | ||
Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937. | Q33826817 | ||
Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist | Q33964630 | ||
Enhanced leukotriene synthesis in leukocytes of atopic and asthmatic subjects | Q34402988 | ||
CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells | Q34662206 | ||
Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes | Q34681509 | ||
Increase in urinary leukotriene LTE4 levels in acute asthma: correlation with airflow limitation | Q35536504 | ||
Cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammation | Q36339008 | ||
Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblasts | Q36353710 | ||
T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4. | Q36376120 | ||
Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells | Q36929692 | ||
Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production | Q36991150 | ||
Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17. | Q37193227 | ||
Prostaglandin E2 deficiency causes a phenotype of aspirin sensitivity that depends on platelets and cysteinyl leukotrienes | Q37240446 | ||
GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4. | Q37261678 | ||
Leukotriene E4-induced airway hyperresponsiveness of guinea pig tracheal smooth muscle to histamine and evidence for three separate sulfidopeptide leukotriene receptors | Q37562061 | ||
Pathogenesis of aspirin-exacerbated respiratory disease and reactions | Q38103710 | ||
A randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthma | Q39290977 | ||
Functional expression of cysteinyl leukotriene receptors on human platelets | Q39708804 | ||
A role for inflammatory mediators in heterologous desensitization of CysLT1 receptor in human monocytes. | Q39766422 | ||
Genome-wide methylation profile of nasal polyps: relation to aspirin hypersensitivity in asthmatics | Q39811129 | ||
Correlation between expression of 5-lipoxygenase-activating protein, 5-lipoxygenase, and cellular leukotriene synthesis | Q41714750 | ||
Cutting edge: Leukotriene C4 activates mouse platelets in plasma exclusively through the type 2 cysteinyl leukotriene receptor | Q42153378 | ||
Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma | Q42745189 | ||
Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase. | Q42809059 | ||
Attenuated zymosan-induced peritoneal vascular permeability and IgE-dependent passive cutaneous anaphylaxis in mice lacking leukotriene C4 synthase | Q43586333 | ||
IL-13 and IL-4 up-regulate cysteinyl leukotriene 1 receptor expression in human monocytes and macrophages | Q43710176 | ||
Inhaled leukotriene E(4), but not leukotriene D(4), increased airway inflammatory cells in subjects with atopic asthma | Q43796672 | ||
Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses | Q43946818 | ||
Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma | Q69352841 | ||
Comparative contractile responses to sulfidopeptide leukotrienes in normal and asthmatic human subjects | Q69829869 | ||
Bronchoconstrictor effects of leukotriene C in humans | Q70298182 | ||
Comparative bronchoconstrictor effects of histamine, leukotriene C, and leukotriene D in normal human volunteers | Q70629252 | ||
Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: a 6-month randomized multicenter trial. Zileuton Study Group | Q71823499 | ||
Expression of LTC4 synthase during the development of eosinophils in vitro from cord blood progenitors | Q71834809 | ||
Activation of protein kinase C down-regulates leukotriene C4 synthase activity and attenuates cysteinyl leukotriene production in an eosinophilic substrain of HL-60 cells | Q72037718 | ||
Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects | Q72252746 | ||
Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma | Q72352958 | ||
The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma | Q72605042 | ||
Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: a randomized, placebo-controlled clinical trial | Q73784748 | ||
Cromolyn sodium prevents bronchoconstriction and urinary LTE4 excretion in aspirin-induced asthma | Q74289995 | ||
Characteristics of leukotriene biosynthesis by human granulocytes in presence of plasma | Q74345295 | ||
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics | Q74490010 | ||
Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects | Q77178375 | ||
IL-5 increases expression of 5-lipoxygenase-activating protein and translocates 5-lipoxygenase to the nucleus in human blood eosinophils | Q77929292 | ||
Cyclooxygenase-2 mRNA is downexpressed in nasal polyps from aspirin-sensitive asthmatics | Q77950275 | ||
Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammation | Q80967764 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial 3.0 Unported | Q18810331 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 288-95 | |
P577 | publication date | 2014-07-01 | |
P1433 | published in | Allergy, Asthma & Immunology Research | Q13429052 |
P1476 | title | Cysteinyl leukotrienes and their receptors; emerging concepts | |
P478 | volume | 6 |
Q36636612 | A Case of Pranlukast-Induced Anaphylactic Shock |
Q38931124 | Aspirin-exacerbated respiratory disease and current treatment modalities |
Q38455960 | Aspirin-exacerbated respiratory disease: characteristics and management strategies |
Q104495231 | Biological and physical approaches on the role of piplartine (piperlongumine) in cancer |
Q26767423 | Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases |
Q40110465 | Computational Modeling of Competitive Metabolism between ω3- and ω6-Polyunsaturated Fatty Acids in Inflammatory Macrophages |
Q39000200 | Current complications and treatment of aspirin-exacerbated respiratory disease |
Q41044958 | Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders |
Q91142640 | Cysteinyl leukotriene receptor 2 drives lung immunopathology through a platelet and high mobility box 1-dependent mechanism |
Q36080707 | Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease |
Q38272869 | Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling. |
Q92340531 | Expression of COX-1, COX-2, 5-LOX and CysLT2 in nasal polyps and bronchial tissue of patients with aspirin exacerbated airway disease |
Q51000114 | High-affinity pan-specific monoclonal antibodies that target cysteinyl leukotrienes and show efficacy in an acute model of colitis. |
Q90445119 | Ibuprofen-induced localized frontal and temporal forehead swellings: A rare case report |
Q47958695 | Identification of phenotypic clusters of nonsteroidal anti-inflammatory drugs exacerbated respiratory disease |
Q28076134 | Insights into Group 2 Innate Lymphoid Cells in Human Airway Disease |
Q38699307 | Leukotriene C4 Potentiates IL-33-Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation |
Q48939543 | Leukotriene Receptor Antagonists and Antiallergy Drugs |
Q38973369 | Leukotriene Receptor Antagonists for the Treatment of Asthma in Elderly Patients |
Q28276574 | Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets |
Q51469727 | Metabolomic analysis identifies potential diagnostic biomarkers for aspirin-exacerbated respiratory disease. |
Q36504328 | P2Y12 antagonist attenuates eosinophilic inflammation and airway hyperresponsiveness in a mouse model of asthma |
Q26769046 | Pharmacotherapy in the management of asthma in the elderly: a review of clinical studies |
Q35914881 | Phenotype-based Discovery of 2-[(E)-2-(Quinolin-2-yl)vinyl]phenol as a Novel Regulator of Ocular Angiogenesis |
Q33734371 | Plasma LTE4/PGF2α Ratio and Blood Eosinophil Count Are Increased in Elderly Asthmatics With Previous Asthma Exacerbation. |
Q38899898 | Regulation of inflammation by lipid mediators in oral diseases |
Q28081823 | Seven steps to the diagnosis of NSAIDs hypersensitivity: how to apply a new classification in real practice? |
Q36240870 | Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function |
Q26699997 | Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector |
Q90341485 | Systematic Understanding of Bioactive Lipids in Neuro-Immune Interactions: Lessons from an Animal Model of Multiple Sclerosis |
Q90862887 | Targeting cell signaling in allergic asthma |
Q26999358 | The 5-lipoxygenase pathway: oxidative and inflammatory contributions to the Alzheimer's disease phenotype |
Q64107048 | The complex pathophysiology of allergic rhinitis: scientific rationale for the development of an alternative treatment option |
Q34483226 | The efficacy and safety of selective H1-antihistamine versus leukotriene receptor antagonist for seasonal allergic rhinitis: a meta-analysis |
Q90277653 | The mercapturomic profile of health and non-communicable diseases |
Q26749097 | Update on the Management of Aspirin-Exacerbated Respiratory Disease |
Search more.