| scholarly article | Q13442814 |
| P2093 | author name string | K F Austen | |
| J A Boyce | |||
| B K Lam | |||
| J F Penrose | |||
| F H Hsieh | |||
| P2860 | cites work | Characterization of the human cysteinyl leukotriene CysLT1 receptor | Q22010199 |
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| Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes | Q24545573 | ||
| cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase | Q24561546 | ||
| Purification to homogeneity and the N-terminal sequence of human leukotriene C4 synthase: a homodimeric glutathione S-transferase composed of 18-kDa subunits | Q24563352 | ||
| Molecular cloning and expression of human leukotriene-C4 synthase | Q24563556 | ||
| Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4 | Q24564369 | ||
| Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma | Q24564777 | ||
| Interconversion of leukotrienes catalyzed by purified gamma-glutamyl transpeptidase: concomitant formation of leukotriene D4 and gamma-glutamyl amino acids | Q27863434 | ||
| Induction of the high-affinity IgE receptor (Fc epsilon RI) on human mast cells by IL-4 | Q71784302 | ||
| Expression of LTC4 synthase during the development of eosinophils in vitro from cord blood progenitors | Q71834809 | ||
| Leukotriene E4 and granulocytic infiltration into asthmatic airways | Q72215711 | ||
| Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations | Q72409368 | ||
| Heterogeneity of human mast cells | Q72712445 | ||
| Arachidonic acid metabolism in purified human lung mast cells | Q72725472 | ||
| Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics | Q73271383 | ||
| Prostaglandin D2 as a mediator of allergic asthma | Q73556211 | ||
| Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese population | Q73885838 | ||
| IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and m | Q77399387 | ||
| IL-5 increases expression of 5-lipoxygenase-activating protein and translocates 5-lipoxygenase to the nucleus in human blood eosinophils | Q77929292 | ||
| Molecular cloning of the gene for human leukotriene C4 synthase. Organization, nucleotide sequence, and chromosomal localization to 5q35 | Q28278365 | ||
| A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP | Q28302244 | ||
| Rapid import of cytosolic 5-lipoxygenase into the nucleus of neutrophils after in vivo recruitment and in vitro adherence | Q28306480 | ||
| The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus | Q28512134 | ||
| Purification and characterisation of leukotriene A4 hydrolase from rat neutrophils | Q28583055 | ||
| The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils | Q28622214 | ||
| Characterization of the human cysteinyl leukotriene 2 receptor | Q30305734 | ||
| Generation of a novel stem cell factor-dependent mast cell progenitor. | Q31973461 | ||
| Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence | Q33555966 | ||
| 5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation | Q34215256 | ||
| Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, p cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing [...] | Q34249915 | ||
| Interleukin-4 and interleukin-13: their similarities and discrepancies | Q34488885 | ||
| Enhanced expression of cyclo-oxygenase isoenzyme 2 (COX-2) in asthmatic airways and its cellular distribution in aspirin-sensitive asthma | Q35563238 | ||
| Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosa | Q36350812 | ||
| T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro | Q36375111 | ||
| Generation of leukotrienes by purified human lung mast cells | Q36986695 | ||
| Cell-specific transcription of leukotriene C(4) synthase involves a Kruppel-like transcription factor and Sp1. | Q38314357 | ||
| Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation | Q40908061 | ||
| Translocation and Leukotriene Synthetic Capacity of Nuclear 5-Lipoxygenase in Rat Basophilic Leukemia Cells and Alveolar Macrophages | Q40972184 | ||
| TGF-beta increases leukotriene C4 synthase expression in the monocyte-like cell line, THP-1. | Q40978585 | ||
| cDNA Cloning, Expression, Mutagenesis, Intracellular Localization, and Gene Chromosomal Assignment of Mouse 5-Lipoxygenase | Q41323177 | ||
| Effect of a leukotriene antagonist, LY171883, on cold air-induced bronchoconstriction in asthmatics | Q41331562 | ||
| c-kit ligand mediates increased expression of cytosolic phospholipase A2, prostaglandin endoperoxide synthase-1, and hematopoietic prostaglandin D2 synthase and increased IgE-dependent prostaglandin D2 generation in immature mouse mast cells | Q41368938 | ||
| Correlation between expression of 5-lipoxygenase-activating protein, 5-lipoxygenase, and cellular leukotriene synthesis | Q41714750 | ||
| Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE. | Q42258225 | ||
| Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial Group | Q42556993 | ||
| Demonstration of the origin of human mast cells from CD34+ bone marrow progenitor cells | Q42829029 | ||
| Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects | Q44241228 | ||
| The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene | Q44659531 | ||
| Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators | Q44767894 | ||
| Purification and characterization of human skin mast cells. Evidence for human mast cell heterogeneity | Q45097717 | ||
| Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge | Q45402860 | ||
| Mast cells contain spleen-type prostaglandin D synthetase | Q49136546 | ||
| Airway mucosal inflammation even in patients with newly diagnosed asthma. | Q51670975 | ||
| Molecular Cloning of the Gene for Human Leukotriene C Synthase | Q56565417 | ||
| Human uterine mast cells. Isolation, purification, characterization, ultrastructure, and pharmacology | Q67698491 | ||
| Isolation and characterization of human intestinal mucosal mast cells | Q69383692 | ||
| Mast cells in rat gastrointestinal mucosa. I. Effects of fixation | Q70067435 | ||
| Slow-reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro | Q70469921 | ||
| Reversible translocation of 5-lipoxygenase in mast cells upon IgE/antigen stimulation | Q70589379 | ||
| Interleukin-3 in bronchial biopsies from nonasthmatics and patients with mild and allergen-induced asthma | Q70838986 | ||
| Effects of leukotriene D on the airways in asthma | Q71655873 | ||
| Interleukin-3 regulates development of the 5-lipoxygenase/leukotriene C4 synthase pathway in mouse mast cells | Q71742978 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | mast cell | Q191989 |
| interleukins | Q194908 | ||
| P304 | page(s) | 123-133 | |
| P577 | publication date | 2001-01-01 | |
| P1433 | published in | Journal of Experimental Medicine | Q3186912 |
| P1476 | title | T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4. | |
| P478 | volume | 193 |
| Q54411785 | 2-Aminoethoxydiphenyl borate administration into the nostril alleviates murine allergic rhinitis |
| Q24804581 | 5-Lipoxygenase Pathway, Dendritic Cells, and Adaptive Immunity |
| Q28191619 | 5-lipoxygenase and FLAP |
| Q42576928 | Activation of group 2 innate lymphoid cells: a new role for cysteinyl leukotrienes |
| Q92772379 | Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling |
| Q42129014 | Aspirin induces IL-4 production: augmented IL-4 production in aspirin-exacerbated respiratory disease |
| Q90523162 | Aspirin sensitivity: Lessons in the regulation (and dysregulation) of mast cell function |
| Q26750424 | Aspirin-exacerbated respiratory disease: pathophysiological insights and clinical advances |
| Q36301489 | Association of Leukotriene C4 Synthase A-444C Polymorphism with Asthma and Asthma Phenotypes in Romanian Population |
| Q43586333 | Attenuated zymosan-induced peritoneal vascular permeability and IgE-dependent passive cutaneous anaphylaxis in mice lacking leukotriene C4 synthase |
| Q28196491 | Bronchial mast cells are the dominating LTC4S-expressing cells in aspirin-tolerant asthma |
| Q90288923 | COX-1 mediates IL-33-induced extracellular signal-regulated kinase activation in mast cells: Implications for aspirin sensitivity |
| Q45269488 | Changes of 5-lipoxygenase pathway and proinflammatory mediators in cerebral cortex and lung tissue of sensitized rats. |
| Q30428097 | Characterization of a novel human mast cell line that responds to stem cell factor and expresses functional FcεRI |
| Q30311131 | Characterization of interleukin-4-stimulated nasal polyp fibroblasts |
| Q40792730 | Co-localization of leukotriene a4 hydrolase with 5-lipoxygenase in nuclei of alveolar macrophages and rat basophilic leukemia cells but not neutrophils |
| Q24633568 | Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes |
| Q24632991 | Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells |
| Q28243252 | Cysteinyl leukotrienes and their receptors; emerging concepts |
| Q36370341 | Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists |
| Q28219122 | Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis |
| Q33625414 | Dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization |
| Q30275780 | Eosinophils and Mast Cells in Aspirin-Exacerbated Respiratory Disease |
| Q24673057 | Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R |
| Q30300955 | Factors driving the aspirin exacerbated respiratory disease phenotype |
| Q34063491 | Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells |
| Q28575606 | Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4 |
| Q34997664 | Human bronchial fibroblasts express the 5-lipoxygenase pathway |
| Q41864224 | Human mast cells express multiple EP receptors for prostaglandin E2 that differentially modulate activation responses |
| Q36819955 | Human mast cells, bacteria, and intestinal immunity |
| Q42806538 | Identification of two novel nuclear import sequences on the 5-lipoxygenase protein |
| Q30577312 | Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33. |
| Q64999562 | Interferon-gamma-dependent inhibition of late allergic airway responses and eosinophilia by CD8+ gammadelta T cells. |
| Q36834591 | Interleukin-13 signaling and its role in asthma |
| Q35494300 | Interleukin-13, but not indomethacin, increases cysteinyl-leukotriene synthesis in human lung macrophages |
| Q30428747 | Interleukin-4 in the Generation of the AERD Phenotype: Implications for Molecular Mechanisms Driving Therapeutic Benefit of Aspirin Desensitization |
| Q35190740 | Leukotriene C(4) synthase |
| Q46091192 | Leukotriene C4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals |
| Q34159114 | Leukotriene C4 synthase: a pivotal enzyme in cellular biosynthesis of the cysteinyl leukotrienes |
| Q30455019 | Leukotriene Inhibitors in Sinusitis |
| Q43819595 | Leukotriene and prostanoid pathway enzymes in bronchial biopsies of seasonal allergic asthmatics |
| Q30433200 | Leukotriene receptors in rhinitis and sinusitis |
| Q44452637 | Leukotriene synthesis is increased by transcriptional up-regulation of 5-lipoxygenase, leukotriene A4 hydrolase, and leukotriene C4 synthase in asthmatic children |
| Q28276574 | Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets |
| Q34613746 | Mast cell growth, differentiation, and death |
| Q28084141 | Mast cell production and response to IL-4 and IL-13 |
| Q36819905 | Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation |
| Q36835143 | Mast cells and mastocytosis |
| Q35906088 | Mast-cell responses to pathogens. |
| Q37865512 | Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents |
| Q35210358 | Minimal persistent inflammation, an emerging concept in the nature and treatment of allergic rhinitis: the possible role of leukotrienes |
| Q38305612 | New insights on the signaling and function of the high-affinity receptor for IgE. |
| Q36348764 | Nuclear localization of 5-lipoxygenase as a determinant of leukotriene B4synthetic capacity |
| Q36677451 | Omalizumab reverses the phenotypic and functional effects of IgE-enhanced Fc epsilonRI on human skin mast cells |
| Q42745189 | Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma |
| Q42809059 | Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase. |
| Q30410446 | Prominent role of IFN-γ in patients with aspirin-exacerbated respiratory disease |
| Q53264281 | Rapid IgE desensitization is antigen specific and impairs early and late mast cell responses targeting FcεRI internalization. |
| Q53590812 | Release of prostaglandin D2 and leukotriene C4 in response to hyperosmolar stimulation of mast cells. |
| Q36287476 | Role of human mast cells and basophils in bronchial asthma |
| Q36240870 | Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function |
| Q28509450 | Structural and functional criteria reveal a new nuclear import sequence on the 5-lipoxygenase protein |
| Q34603405 | Surface CD88 functionally distinguishes the MCTC from the MCT type of human lung mast cell |
| Q43946818 | Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses |
| Q40048581 | The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2. |
| Q46773584 | The cysteinyl leukotrienes: where do they come from? What are they? Where are they going? |
| Q28191630 | The role of mast cells in asthma |
| Q27318045 | Transcriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization |
| Q79740863 | Ultraviolet B irradiation selectively increases the production of interleukin-8 in human cord blood-derived mast cells |
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