Aspirin sensitivity: Lessons in the regulation (and dysregulation) of mast cell function

scientific article published on 01 October 2019

Aspirin sensitivity: Lessons in the regulation (and dysregulation) of mast cell function is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/J.JACI.2019.08.022
P932PMC publication ID7735393
P698PubMed publication ID31587797

P2093author name stringJoshua A Boyce
P2860cites workCysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytesQ24633568
Mast Cell: A Multi-Functional Master CellQ26771463
Cromolyn sodium suppresses eosinophilic inflammation in patients with aspirin-intolerant asthmaQ28188506
Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitisQ28194143
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory diseaseQ28194657
Aspirin-sensitive rhinosinusitis is associated with reduced E-prostanoid 2 receptor expression on nasal mucosal inflammatory cellsQ28194899
Expression of 5-lipoxygenase and cyclooxygenase pathway enzymes in nasal polyps of patients with aspirin-intolerant asthmaQ28196323
Impaired E Prostanoid2 Expression and Resistance to Prostaglandin E2 in Nasal Polyp Fibroblasts from Subjects with Aspirin-Exacerbated Respiratory Disease.Q30279219
Prevalence of aspirin-exacerbated respiratory disease among asthmatic patients: A meta-analysis of the literatureQ34441715
Prostaglandin D₂: a dominant mediator of aspirin-exacerbated respiratory diseaseQ34892917
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulationQ35545787
Evidence for intranasal antinuclear autoantibodies in patients with chronic rhinosinusitis with nasal polypsQ36062767
Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation PathwayQ36119388
Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonistsQ36370341
T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4.Q36376120
Leukotriene E4 activates peroxisome proliferator-activated receptor gamma and induces prostaglandin D2 generation by human mast cellsQ36711106
Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitisQ37138334
The cytokine interleukin-33 mediates anaphylactic shockQ37238924
Prostaglandin E2 deficiency causes a phenotype of aspirin sensitivity that depends on platelets and cysteinyl leukotrienesQ37240446
Genome-wide methylation profile of nasal polyps: relation to aspirin hypersensitivity in asthmaticsQ39811129
Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory diseaseQ41146048
Human mast cells express multiple EP receptors for prostaglandin E2 that differentially modulate activation responsesQ41864224
Low E-prostanoid 2 receptor levels and deficient induction of the IL-1β/IL-1 type I receptor/COX-2 pathway: Vicious circle in patients with aspirin-exacerbated respiratory disease.Q42484997
KIT Inhibition by Imatinib in Patients with Severe Refractory AsthmaQ43575814
Certain subphenotypes of aspirin-exacerbated respiratory disease distinguished by latent class analysis.Q45986027
Low prostaglandin E2 and cyclooxygenase expression in nasal mucosa fibroblasts of aspirin-intolerant asthmaticsQ46240727
Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthmaQ46363432
Type 2 Cysteinyl Leukotriene Receptors Drive IL-33-Dependent Type 2 Immunopathology and Aspirin Sensitivity.Q47669026
Reduced expression of the prostaglandin E2 receptor E-prostanoid 2 on bronchial mucosal leukocytes in patients with aspirin-sensitive asthmaQ48020876
Organization of secondary lymphoid tissue and local IgE formation to Staphylococcus aureus enterotoxins in nasal polyp tissue.Q49126882
The atopy trait in hypersensitivity to nonsteroidal anti-inflammatory drugs.Q51021309
Aspirin-Exacerbated Respiratory Disease--New Prime Suspects.Q51550145
Omalizumab reduces cysteinyl leukotriene and 9α,11β-prostaglandin F2 overproduction in aspirin-exacerbated respiratory disease.Q51574958
Elevated total serum IgE in nonatopic patients with aspirin-exacerbated respiratory disease.Q51699073
Leukotriene E4 induces airflow obstruction and mast cell activation via the CysLT1 receptor.Q52727846
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammationQ57023002
The Pivotal Role of 5-Lipoxygenase Products in the Reaction of Aspirin-sensitive Asthmatics to AspirinQ57240791
Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease (AERD)Q58556061
Allergic inflammatory memory in human respiratory epithelial progenitor cellsQ59050242
Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-αQ59092114
Urinary Leukotriene E4Concentrations Increase after Aspirin Challenge in Aspirin-sensitive Asthmatic SubjectsQ67915846
Sodium cromoglycate nebulized solution has an acute bronchodilative effect in patients with aspirin-intolerant asthma (AIA)Q67986774
Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthmaQ69352841
Slow-reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitroQ70469921
Comparative bronchoconstrictor effects of histamine, leukotriene C, and leukotriene D in normal human volunteersQ70629252
Inflammatory cell populations in bronchial biopsies from aspirin-sensitive asthmatic subjectsQ70839055
Inhaled PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthmaQ70906164
Preferential generation of prostaglandin D2 by rat and human mast cellsQ71578709
Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthmaQ72352958
Cysteinyl leukotrienes overproduction and mast cell activation in aspirin-provoked bronchospasm in asthmaQ72964940
Attenuation of aspirin-induced bronchoconstriction by sodium cromoglycate and nedocromil sodiumQ73227991
The effect of an anti-IgE monoclonal antibody on the early- and late-phase responses to allergen inhalation in asthmatic subjectsQ73442941
Cromolyn sodium prevents bronchoconstriction and urinary LTE4 excretion in aspirin-induced asthmaQ74289995
Interaction of PGH synthase isozymes-1 and -2 with nonsteroidal anti-inflammatory drugsQ74454826
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmaticsQ74490010
Bronchial hyperresponsiveness, hypersensitivity to analgesics and urinary leukotriene E4 excretion in patients with aspirin-intolerant asthmaQ77451452
Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cellsQ80736011
Omalizumab can inhibit respiratory reaction during aspirin desensitizationQ88734764
COX-1 mediates IL-33-induced extracellular signal-regulated kinase activation in mast cells: Implications for aspirin sensitivityQ90288923
Cysteinyl leukotriene receptor 2 drives lung immunopathology through a platelet and high mobility box 1-dependent mechanismQ91142640
Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-exacerbated Respiratory Disease. A Prospective TrialQ93056163
P433issue4
P921main subjectaspirinQ18216
mast cellQ191989
P1104number of pages7
P304page(s)875-881
P577publication date2019-10-01
P1433published inThe Journal of Allergy and Clinical ImmunologyQ7743550
P1476titleAspirin sensitivity: Lessons in the regulation (and dysregulation) of mast cell function
P478volume144

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cites work (P2860)
Q90108933Omalizumab for Aspirin-Hypersensitivity and Leukotriene Overproduction in Aspirin-Exacerbated Respiratory Disease: A Randomized Trial
Q104496576Systematic review of outcomes for endoscopic sinus surgery and subsequent aspirin desensitization in aspirin-exacerbated respiratory disease

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