| scholarly article | Q13442814 |
| P50 | author | Masja de Haas | Q47654799 |
| Marcel Kool | Q90637389 | ||
| P2093 | author name string | P Borst | |
| J A Juijn | |||
| M J van Eijk | |||
| R J Scheper | |||
| G L Scheffer | |||
| F Baas | |||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | multiple drug resistance | Q643839 |
| P304 | page(s) | 3537-47 | |
| P577 | publication date | 1997-08-15 | |
| P1433 | published in | Cancer Research | Q326097 |
| P1476 | title | Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines | |
| P478 | volume | 57 |
| Q39173262 | (99m)Tc(N)-DBODC(5), a potential radiolabeled probe for SPECT of multidrug resistance: in vitro study. |
| Q46382844 | A fluorometric screening assay for drug efflux transporter activity in the blood-brain barrier |
| Q36254826 | A new aspect on glutathione-associated biological function of MRP/GS-X pump and its gene expression |
| Q36617816 | A novel drug-phospholipid complex enriched with micelles: preparation and evaluation in vitro and in vivo |
| Q36868737 | A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration |
| Q21246014 | ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal |
| Q26823286 | ABC transporters in fish species: a review |
| Q41983373 | ABCC4 is required for cell proliferation and tumorigenesis in non-small cell lung cancer |
| Q36245109 | ABCC5 is required for cAMP-mediated hindgut invagination in sea urchin embryos |
| Q35595837 | ATP binding cassette transporter gene expression in rat liver progenitor cells |
| Q40962980 | ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1. |
| Q36381928 | ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs |
| Q24811895 | ATP-binding cassette (ABC) transporters in normal and pathological lung |
| Q34843023 | ATP-binding cassette efflux transporters in human placenta |
| Q58798114 | ATP-binding cassette transporters in progression and clinical outcome of pancreatic cancer: What is the way forward? |
| Q36793431 | ATP11B mediates platinum resistance in ovarian cancer |
| Q30681104 | Anthrapyridones, a novel group of antitumour non-cross resistant anthraquinone analogues. Synthesis and molecular basis of the cytotoxic activity towards K562/DOX cells |
| Q42159042 | Anti-cancer-prostaglandin-induced cell-cycle arrest and its modulation by an inhibitor of the ATP-dependent glutathione S-conjugate export pump (GS-X pump). |
| Q44485059 | Apparent lack of Mrp1-mediated efflux at the luminal side of mouse blood-brain barrier endothelial cells |
| Q39680524 | Association of ABCC2 and CDDP-Resistance in Two Sublines Resistant to CDDP Derived from a Human Nasopharyngeal Carcinoma Cell Line |
| Q36619759 | Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to Paclitaxel |
| Q30535334 | Bilirubin protects astrocytes from its own toxicity by inducing up-regulation and translocation of multidrug resistance-associated protein 1 (Mrp1) |
| Q38276429 | Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy? |
| Q40972218 | Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione. |
| Q33458922 | Cellular uptake and antiproliferative effects of 11-oxo-eicosatetraenoic acid |
| Q44410490 | Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood–brain barrier |
| Q39876230 | Characterization of the ATP-binding cassette transporter gene expression profile in Y79: a retinoblastoma cell line |
| Q40716260 | Characterization of the efflux transporter(s) responsible for restricting intestinal mucosa permeation of the coumarinic acid-based cyclic prodrug of the opioid peptide DADLE. |
| Q43756942 | Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate |
| Q44834355 | Chemosensitivity assessed by collagen gel droplet embedded culture drug sensitivity test, and MDR1, MRP1, and MRP2 mRNA expression in human colorectal adenocarcinomas |
| Q35498362 | Cholangiocyte bile salt transporters in cholesterol gallstone-susceptible and resistant inbred mouse strains |
| Q35090225 | Cholestasis. |
| Q28577126 | Cloning and characterization of the rat multidrug resistance-associated protein 1 |
| Q42958379 | Co-expression of CD147/EMMPRIN with monocarboxylate transporters and multiple drug resistance proteins is associated with epithelial ovarian cancer progression. |
| Q36982278 | Combination of gambogic acid with cisplatin enhances the antitumor effects on cisplatin-resistant lung cancer cells by downregulating MRP2 and LRP expression |
| Q54082066 | Comparison of the anticancer effect of free and HPMA copolymer-bound adriamycin in human ovarian carcinoma cells. |
| Q27314587 | Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea. |
| Q33737434 | Control of metazoan heme homeostasis by a conserved multidrug resistance protein |
| Q37311836 | Crucial role for phylogenetically conserved cytoplasmic loop 3 in ABCC4 protein expression |
| Q49562948 | DHA induces apoptosis of human malignant breast cancer tissues by the TLR-4/PPAR-α pathways. |
| Q53523852 | DNA bridging of yeast chromosomes VIII leads to near-reciprocal translocation and loss of heterozygosity with minor cellular defects. |
| Q48157328 | Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics |
| Q30419764 | Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice |
| Q36292935 | Determinants of CPT-11 and SN-38 activities in human lung cancer cells |
| Q33180943 | Development of multidrug-resistance convertors: sense or nonsense? |
| Q40949307 | Differences in substrate specificity among glutathione conjugates (GS-X) pump family members: comparison between multidrug resistance-associated protein and a novel transporter expressed on a cisplatin-resistant cell line (KCP-4). |
| Q46967012 | Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes |
| Q35795744 | Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 Proteins |
| Q24564700 | Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA |
| Q36642267 | Drug resistance features and S-phase fraction as possible determinants for drug response in a panel of human ovarian cancer xenografts |
| Q27692033 | Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms |
| Q35788063 | Drug transfer and metabolism by the human placenta. |
| Q43834993 | Effect of probenecid on fluorescein transport in the central nervous system using in vitro and in vivo models |
| Q40500023 | Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux. |
| Q46041576 | Efflux protein expression in human retinal pigment epithelium cell lines. |
| Q34003651 | Effluxing ABC transporters in human corneal epithelium. |
| Q37206023 | Enhancing chemosensitivity in oral squamous cell carcinoma by lentivirus vector-mediated RNA interference targeting EGFR and MRP2. |
| Q36115145 | Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP). |
| Q24685159 | Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart |
| Q39238708 | Expression levels of multidrug resistance-associated protein 4 (MRP4) in human leukemia and lymphoma cell lines, and the inhibitory effects of the MRP-specific inhibitor MK-571 on methotrexate distribution in rats |
| Q37666690 | Expression of Drug-Resistant Factor Genes in Hepatocellular Carcinoma Patients Undergoing Chemotherapy with Platinum Complex by Arterial Infusion |
| Q54102440 | Expression of MRP and cMOAT in childhood neuroblastomas and malignant liver tumors and its relevance to clinical behavior. |
| Q48761116 | Expression of drug resistance proteins Pgp, MRP1, MRP3, MRP5 and GST-pi in human glioma. |
| Q34239688 | Expression of multidrug resistance associated protein 5 (MRP5) on cornea and its role in drug efflux |
| Q46845549 | Expression of multidrug resistance proteins (Mrps) in astrocytes of the mouse brain: a single cell RT-PCR study. |
| Q40790894 | Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor |
| Q41444935 | Expression of multidrug resistance-associated protein 2 in human gallbladder carcinoma |
| Q24540140 | Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome |
| Q43608647 | Glutathione content is correlated with the sensitivity of lines of PC12 cells to cisplatin without a corresponding change in the accumulation of platinum. |
| Q24629542 | Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy |
| Q36316764 | Harnessing drug resistance: using ABC transporter proteins to target cancer cells |
| Q54374388 | Heterogeneity of anticancer drug sensitivity in squamous cell carcinoma of the tongue. |
| Q24623958 | High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance |
| Q37422773 | Human immunodeficiency virus protease inhibitors interact with ATP binding cassette transporter 4/multidrug resistance protein 4: a basis for unanticipated enhanced cytotoxicity |
| Q40379793 | Human multidrug resistance associated protein 4 confers resistance to camptothecins. |
| Q44105235 | Immortalization of human melanocytes does not alter the de novo properties of nitric oxide to induce cell detachment from extracellular matrix components via cGMP. |
| Q37352731 | In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer |
| Q54069066 | In vivo cisplatin resistance depending upon canalicular multispecific organic anion transporter (cMOAT). |
| Q31088404 | Increased expression of beta 2-microglobulin in multidrug-resistant tumour cells |
| Q39617875 | Increased expression of multidrug resistance related proteins Pgp, MRP1, and LRP/MVP occurs early in colorectal carcinogenesis |
| Q40067043 | Indomethacin induces apoptosis via a MRP1-dependent mechanism in doxorubicin-resistant small-cell lung cancer cells overexpressing MRP1. |
| Q38012447 | Inhaled chemotherapy in lung cancer: future concept of nanomedicine |
| Q28344522 | Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport |
| Q34325960 | Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes |
| Q39474195 | Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells. |
| Q34301527 | Involvement of the drug transporters p glycoprotein and multidrug resistance-associated protein Mrp2 in telithromycin transport |
| Q32063211 | Involvement of the multidrug resistance protein 3 in drug sensitivity and its expression in human glioma |
| Q37058949 | LOSS of Mrp1 alters detoxification enzyme expression in a tissue- and hormonal-status-specific manner |
| Q39932802 | Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin |
| Q44084745 | Lung resistance-related protein (LRP) expression in malignant ascitic cells as a prognostic marker for advanced ovarian serous carcinoma. |
| Q42053609 | MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver |
| Q34502459 | MRP subfamily transporters and resistance to anticancer agents |
| Q24650550 | MRP3, an organic anion transporter able to transport anti-cancer drugs |
| Q30988770 | MRP3: a molecular target for human glioblastoma multiforme immunotherapy |
| Q42141601 | Mechanisms of Cisplatin-Induced Apoptosis and of Cisplatin Sensitivity: Potential of BIN1 to Act as a Potent Predictor of Cisplatin Sensitivity in Gastric Cancer Treatment |
| Q37313443 | Mechanisms of the penetration of blood-borne substances into the brain |
| Q36254848 | Membrane topology of the human multidrug resistance-associated protein (MRP) and its homologs |
| Q38796029 | Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation. |
| Q42283115 | Modelling of the blood-brain barrier transport of morphine-3-glucuronide studied using microdialysis in the rat: involvement of probenecid-sensitive transport |
| Q28552735 | Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer |
| Q40652100 | Molecular cytogenetic characterization of drug-resistant leukemia cell lines by comparative genomic hybridization and fluorescence in situ hybridization |
| Q37666255 | Molecular mechanisms behind the resistance of cisplatin in germ cell tumours |
| Q37958163 | Multidrug resistance associated proteins in multidrug resistance. |
| Q36404168 | Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage |
| Q86003614 | Multidrug resistance protein 4 (MRP4) polymorphisms impact the 6-mercaptopurine dose tolerance during maintenance therapy in Japanese childhood acute lymphoblastic leukemia |
| Q24601963 | Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases |
| Q24673081 | Multidrug resistance related molecules in human and murine lung |
| Q40138673 | Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm |
| Q40579600 | Multidrug resistance-associated protein MRP1 expression in human gliomas: chemosensitization to vincristine and etoposide by indomethacin in human glioma cell lines overexpressing MRP1. |
| Q36439713 | Multidrug resistance-associated proteins 3, 4, and 5. |
| Q24681283 | Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs |
| Q37218229 | Multidrug-resistant protein-3 gene regulation by the transcription factor Nrf2 in human bronchial epithelial and non-small-cell lung carcinoma. |
| Q42518189 | Multiple pathways for fluoroquinolone secretion by human intestinal epithelial (Caco-2) cells |
| Q35669404 | N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids |
| Q41618394 | Net secretion of furosemide is subject to indomethacin inhibition, as observed in Caco-2 monolayers and excised rat jejunum |
| Q54950879 | Neurosteroid Transport in the Brain: Role of ABC and SLC Transporters. |
| Q38837269 | Nitric Oxide Synthase-2-Derived Nitric Oxide Drives Multiple Pathways of Breast Cancer Progression |
| Q42582684 | No evidence for the involvement of the multidrug resistance-associated protein and/or the monocarboxylic acid transporter in the intestinal transport of fluvastatin in the rat |
| Q37139330 | Novel Anticancer Platinum(IV) Complexes with Adamantylamine: Their Efficiency and Innovative Chemotherapy Strategies Modifying Lipid Metabolism |
| Q43012033 | Nucleotide binding to the human multidrug resistance protein 3, MRP3. |
| Q24670255 | Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma |
| Q36254844 | P-glycoprotein structure and evolutionary homologies |
| Q34351924 | PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis |
| Q42214835 | PPAR Medicines and Human Disease: The ABCs of It All. |
| Q40767821 | Paclitaxel and SN-38 overcome cisplatin resistance of ovarian cancer cell lines by down-regulating the influx and efflux system of cisplatin |
| Q53793272 | Pharmacogenetics of ABCB5, ABCC5 and RLIP76 and doxorubicin pharmacokinetics in Asian breast cancer patients. |
| Q37266833 | Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology |
| Q36995742 | Polymorphic transporters and platinum pharmacodynamics |
| Q36490749 | Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin |
| Q40927437 | Potent interaction of flavopiridol with MRP1 |
| Q33180580 | Preclinical perspectives on platinum resistance |
| Q90650446 | Prevalence of ABCC3-1767G/A polymorphism among patients with antiretroviral-associated hepatotoxicity |
| Q89638333 | Quantitative site- and structure-specific N-glycoproteomics characterization of differential N-glycosylation in MCF-7/ADR cancer stem cells |
| Q37121662 | Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. |
| Q33886564 | Recombinant single-chain variable fragment antibodies against extracellular epitopes of human multidrug resistance protein MRP3 for targeting malignant gliomas |
| Q35690177 | Regulation of hepatic ABCC transporters by xenobiotics and in disease states |
| Q36944317 | Renal xenobiotic transporters are differentially expressed in mice following cisplatin treatment |
| Q64092084 | Reproducibility of pharmacogenetics findings for paclitaxel in a heterogeneous population of patients with lung cancer |
| Q39043344 | Reversal effect of BM-cyclin 1 on multidrug resistance by down-regulating MRP2 in BALB/C nude mice bearing C-A120 cells |
| Q36648809 | Reversal of Taxol resistance in hepatoma by cyclosporin A: involvement of the PI-3 kinase-AKT 1 pathway |
| Q34992424 | Role of MRP4 and MRP5 in biology and chemotherapy |
| Q57813940 | Role of ZIP8 in regulation of cisplatin sensitivity through Bcl-2 |
| Q26767028 | Role of copper transporters in platinum resistance |
| Q39929809 | Role of glutathione S-transferase P1-1 in the cellular detoxification of cisplatin |
| Q24533593 | Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues |
| Q34627891 | Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma |
| Q37689499 | Role of multidrug transporters in neurotherapeutics |
| Q43009114 | Skeletal muscle expresses the extracellular cyclic AMP-adenosine pathway. |
| Q28508089 | Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4 |
| Q34472849 | Targeted disruption of the PDZK1 gene by homologous recombination |
| Q39056037 | Targeted induction of apoptosis in glioblastoma multiforme cells by an MRP3-specific TRAIL fusion protein in vitro |
| Q27008521 | Targeting inflammation: multiple innovative ways to reduce prostaglandin E₂ |
| Q34129121 | The MRP1-mediated effluxes of arsenic and antimony do not require arsenic-glutathione and antimony-glutathione complex formation. |
| Q42048574 | The effect of rifampin treatment on intestinal expression of human MRP transporters |
| Q37323504 | The extended-MDR phenotype |
| Q35234371 | The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs |
| Q34558556 | The impact of efflux transporters in the brain on the development of drugs for CNS disorders |
| Q37693485 | The role of cyclic nucleotide signaling pathways in cancer: targets for prevention and treatment |
| Q34502464 | The role of half-transporters in multidrug resistance |
| Q28346503 | The sulphonylurea glibenclamide inhibits multidrug resistance protein (MRP1) activity in human lung cancer cells |
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