scholarly article | Q13442814 |
P2093 | author name string | Anthony J Apostoli | |
Christopher J B Nicol | |||
P2860 | cites work | Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies. | Q53224210 |
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CLA-1/SR-BI Is Expressed in Atherosclerotic Lesion Macrophages and Regulated by Activators of Peroxisome Proliferator-Activated Receptors | Q58150309 | ||
Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan | Q73088375 | ||
Bezafibrate induces multidrug-resistance P-Glycoprotein 3 expression in cultured human hepatocytes and humanized livers of chimeric mice | Q80410289 | ||
[TNF-alpha induced reversal of multidrug resistance in human hepatocellular carcinoma cells] | Q80772491 | ||
Reversal of drug resistance in ovarian cancer: where do we go from here? | Q81351629 | ||
Restoration of PPARγ reverses lipid accumulation in alveolar macrophages of GM-CSF knockout mice | Q82241424 | ||
Telmisartan exerts antiatherosclerotic effects by activating peroxisome proliferator-activated receptor-γ in macrophages | Q83809430 | ||
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway | Q22010685 | ||
Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer | Q24307584 | ||
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL | Q24311741 | ||
PPAR and LXR activators regulate ABCA12 expression in human keratinocytes | Q24317055 | ||
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line | Q24338329 | ||
Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis. | Q24531488 | ||
The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention | Q24601222 | ||
A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport | Q24603087 | ||
ABC transporters: the power to change | Q24634548 | ||
Inhibition of cholesterol absorption associated with a PPAR alpha-dependent increase in ABC binding cassette transporter A1 in mice | Q44535882 | ||
High-density lipoproteins: a new potential therapeutic target for the prevention of cardiovascular disease | Q44788570 | ||
Reduction of intracellular cholesterol accumulation in THP-1 macrophages by a combination of rosiglitazone and atorvastatin | Q44926037 | ||
Regulation of ABCA1 expression in human keratinocytes and murine epidermis. | Q45947272 | ||
Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin. | Q45985449 | ||
Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver | Q46440370 | ||
Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing | Q46533975 | ||
Effects of fibrate drugs on expression of ABCA1 and HDL biogenesis in hepatocytes | Q46689993 | ||
PPARalpha agonists positively and negatively regulate the expression of several nutrient/drug transporters in mouse small intestine | Q46918057 | ||
Effects of combined PPARgamma and PPARalpha agonist therapy on reverse cholesterol transport in the Zucker diabetic fatty rat. | Q46923577 | ||
Induction of hepatic transporters multidrug resistance-associated proteins (Mrp) 3 and 4 by clofibrate is regulated by peroxisome proliferator-activated receptor alpha | Q46935309 | ||
The effect of PPARalpha and PPARgamma ligands on inflammation and ABCA1 expression in cultured gallbladder epithelial cells | Q46953942 | ||
Breast cancer resistance protein impacts clinical outcome in platinum-based chemotherapy for advanced non-small cell lung cancer | Q47969061 | ||
Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha. | Q51556346 | ||
Expression of the transcription factor lung Krüppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo. | Q52032014 | ||
Effects of rosiglitazone and atorvastatin on the expression of genes that control cholesterol homeostasis in differentiating monocytes | Q40334975 | ||
The CD44 receptor interacts with P-glycoprotein to promote cell migration and invasion in cancer | Q40390461 | ||
Molecular physiology of reverse cholesterol transport | Q40526401 | ||
Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux. | Q40558191 | ||
PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway | Q40669358 | ||
Human MDR 1 protein overexpression delays the apoptotic cascade in Chinese hamster ovary fibroblasts. | Q41091588 | ||
Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation | Q41451147 | ||
PPAR-gamma: adipogenic regulator and thiazolidinedione receptor | Q41755813 | ||
Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice | Q42526889 | ||
Multidrug resistance in breast cancer: from in vitro models to clinical studies | Q42695791 | ||
PPARγ activates ABCA1 gene transcription but reduces the level of ABCA1 protein in HepG2 cells | Q42856938 | ||
Regulatory action on rosiglitazone by the U.S. Food and Drug Administration | Q42860408 | ||
ABC transporters in cancer: more than just drug efflux pumps. | Q43193922 | ||
Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial | Q43553725 | ||
Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. | Q43579744 | ||
Regulation of rat multidrug resistance protein 2 by classes of prototypical microsomal enzyme inducers that activate distinct transcription pathways | Q43994076 | ||
Induction of hepatic ABC transporter expression is part of the PPARalpha-mediated fasting response in the mouse | Q44269265 | ||
Ceramide stimulates ABCA12 expression via peroxisome proliferator-activated receptor {delta} in human keratinocytes | Q24651375 | ||
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1 | Q28141056 | ||
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis | Q28199913 | ||
The human ATP-binding cassette (ABC) transporter superfamily | Q28204495 | ||
Multidrug resistance in cancer: role of ATP-dependent transporters | Q28208049 | ||
Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines | Q28247169 | ||
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors | Q28276138 | ||
Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages | Q28283333 | ||
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators | Q28304744 | ||
The PPARs: from orphan receptors to drug discovery | Q28371618 | ||
Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse | Q28509638 | ||
ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins | Q28594013 | ||
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype | Q29615563 | ||
Targeting multidrug resistance in cancer | Q29616803 | ||
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines | Q29620217 | ||
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation | Q29620219 | ||
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial | Q30080004 | ||
Conjugated linoleic acid isomers reduce cholesterol accumulation in acetylated LDL-induced mouse RAW264.7 macrophage-derived foam cells | Q30319415 | ||
Bezafibrate stimulates canalicular localization of NBD-labeled PC in HepG2 cells by PPARalpha-mediated redistribution of ABCB4. | Q30764627 | ||
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor | Q30881181 | ||
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway | Q31793810 | ||
Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells. | Q31856730 | ||
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes | Q31932176 | ||
Influence of lipid lowering fibrates on P-glycoprotein activity in vitro. | Q33196280 | ||
Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells | Q33247258 | ||
Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting | Q33293463 | ||
P-glycoprotein: from genomics to mechanism. | Q34272173 | ||
Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux. | Q34277079 | ||
Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999 | Q34360283 | ||
Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients | Q34433361 | ||
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants | Q34488592 | ||
Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner | Q34556218 | ||
Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist. | Q34582444 | ||
Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes. | Q34701840 | ||
Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial | Q34985342 | ||
New strategies in managing and preventing atherosclerosis: focus on HDL. | Q35002306 | ||
Pleiotropic effects of glitazones: a double edge sword? | Q35025858 | ||
Assessing the association of pioglitazone use and bladder cancer through drug adverse event reporting | Q35043204 | ||
Medicinal Chemistry and Actions of Dual and Pan PPAR Modulators | Q35216684 | ||
Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro | Q35753181 | ||
Inflammation in atherosclerosis and diabetes mellitus | Q35813657 | ||
PPARs: therapeutic targets for metabolic disease | Q36110177 | ||
Retinoid x receptor heterodimers in the metabolic syndrome | Q36225102 | ||
PPARs in diseases: control mechanisms of inflammation | Q36353852 | ||
Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein | Q36501176 | ||
The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis | Q36506556 | ||
Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins | Q36525551 | ||
Pathomechanisms of harlequin ichthyosis and ABCA transporters in human diseases | Q36538928 | ||
Effect of fenofibrate therapy and ABCA1 polymorphisms on high-density lipoprotein subclasses in the Genetics of Lipid Lowering Drugs and Diet Network | Q36687632 | ||
PPARs and molecular mechanisms of transrepression | Q36791361 | ||
A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration | Q36868737 | ||
The biochemistry and function of stratum corneum lipids. | Q36885208 | ||
Is there a role for fibrates in the management of dyslipidemia in the metabolic syndrome? | Q36918533 | ||
Role of the MRP1/ABCC1 multidrug transporter protein in cancer | Q37034313 | ||
Ichthyosis update: towards a function-driven model of pathogenesis of the disorders of cornification and the role of corneocyte proteins in these disorders | Q37045238 | ||
Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins | Q37083713 | ||
Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid. | Q37291393 | ||
Direct antiatherosclerotic effects of PPAR agonists | Q37365530 | ||
Troglitazone reverses the multiple drug resistance phenotype in cancer cells. | Q37403238 | ||
On the mechanism for PPAR agonists to enhance ABCA1 gene expression | Q37464644 | ||
PPARs: diverse regulators in energy metabolism and metabolic diseases | Q37681306 | ||
New insights into the role of PPARs | Q37903527 | ||
Mammalian multidrug-resistance proteins (MRPs). | Q37941757 | ||
Atherosclerosis: current pathogenesis and therapeutic options | Q37953777 | ||
Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators. | Q37977108 | ||
Multiple pathways are involved in drug resistance to doxorubicin in an osteosarcoma cell line | Q38290528 | ||
Regulation of breast cancer resistant protein by peroxisome proliferator-activated receptor α in human brain microvessel endothelial cells | Q38328428 | ||
13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages | Q39435368 | ||
Mycophenolic acid induces ATP-binding cassette transporter A1 (ABCA1) expression through the PPARγ-LXRα-ABCA1 pathway | Q39456852 | ||
Reversal of P-glycoprotein-mediated multidrug resistance in SGC7901/VCR cells by PPARgamma activation by troglitazone | Q39691751 | ||
Interaction of thiazolidinediones (glitazones) with the ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein | Q39795888 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P304 | page(s) | 504918 | |
P577 | publication date | 2012-08-07 | |
P1433 | published in | PPAR Research | Q15756406 |
P1476 | title | PPAR Medicines and Human Disease: The ABCs of It All. | |
P478 | volume | 2012 |
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