Blimp1 is a critical determinant of the germ cell lineage in mice

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Blimp1 is a critical determinant of the germ cell lineage in mice is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1029698104
P356DOI10.1038/NATURE03813
P3181OpenCitations bibliographic resource ID609301
P698PubMed publication ID15937476
P5875ResearchGate publication ID7805764

P50authorAzim SuraniQ793786
Michel C. NussenzweigQ24804686
Dónal O'CarrollQ30093304
Bernhard PayerQ30502265
Katia AncelinQ55278842
P2093author name stringAlexander Tarakhovsky
Mitinori Saitou
Sheila C Barton
Yasuhide Ohinata
Yukiko Ono
Mitsue Sano
Tetyana Obukhanych
P2860cites workRTP family members induce functional expression of mammalian odorant receptorsQ24315887
Bmp4 is required for the generation of primordial germ cells in the mouse embryoQ24608134
The fragilis interferon-inducible gene family of transmembrane proteins is associated with germ cell specification in miceQ24793373
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression programQ28216493
Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cellsQ28252567
The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouseQ28508481
Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cellsQ28589532
BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryoQ28591381
Chromatin modification and epigenetic reprogramming in mammalian developmentQ29617802
Detection of messenger RNA by in situ hybridization to tissue sections and whole mountsQ29618776
Stella is a maternal effect gene required for normal early development in miceQ34280753
Reprogramming of genome function through epigenetic inheritanceQ34426502
Primordial germ cells in the mouseQ35544665
Germ cells: finding programs of mass repressionQ35714520
Germ cell specification and migration in Drosophila and beyondQ35842842
Emerging asymmetry and embryonic patterning in early mouse developmentQ35856909
The anterior-posterior axis emerges respecting the morphology of the mouse embryo that changes and aligns with the uterus before gastrulation.Q40533417
A molecular programme for the specification of germ cell fate in mice.Q48558286
A high-resolution, fluorescence-based method for localization of endogenous alkaline phosphatase activity.Q50516067
Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice.Q50779221
Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B CellsQ52005022
Initiation of gastrulation in the mouse embryo is preceded by an apparent shift in the orientation of the anterior-posterior axis.Q52093963
Acquisition of Hox codes during gastrulation and axial elongation in the mouse embryo.Q52103471
The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development.Q52115389
Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strainQ73336003
Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cellsQ73473616
P433issue7048
P407language of work or nameEnglishQ1860
P921main subjectPR domain containing 1, with ZNF domainQ21496758
P1104number of pages7
P304page(s)207-213
P577publication date2005-06-05
P1433published inNatureQ180445
P1476titleBlimp1 is a critical determinant of the germ cell lineage in mice
P478volume436

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Q36496353NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers
Q38984753Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.
Q47136549Nanos promotes epigenetic reprograming of the germline by down-regulation of the THAP transcription factor LIN-15B.
Q28478468Negative regulation of interferon-β gene expression during acute and persistent virus infections
Q33517621New evidence confirms that the mitochondrial bottleneck is generated without reduction of mitochondrial DNA content in early primordial germ cells of mice
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Q46871747No evidence for neo-oogenesis may link to ovarian senescence in adult monkey
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Q50217919Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification.
Q37670100Notch signaling regulates ovarian follicle formation and coordinates follicular growth.
Q28565289Nuclear receptor co-repressor is required to maintain proliferation of normal intestinal epithelial cells in culture and down-modulates the expression of pigment epithelium-derived factor
Q35238314Nuclear reprogramming in mouse primordial germ cells: epigenetic contribution.
Q57039980OTX2 restricts entry to the mouse germline
Q50451732Of Mice and Men: In Vivo and In Vitro Studies of Primordial Germ Cell Specification.
Q37868707Of stem cells and germ cells
Q81715653One PRDM is not enough for germ cell development
Q34409727Ontological differences in first compared to third trimester human fetal placental chorionic stem cells
Q36119945Oocyte family trees: old branches or new stems?
Q24621872Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women
Q36421518Oocyte-like cells induced from mouse spermatogonial stem cells
Q50642120Oocytes.
Q98158654Origin and function of the yolk sac in primate embryogenesis
Q33565484PRDM Proteins: Molecular Mechanisms in Signal Transduction and Transcriptional Regulation
Q37949547PRDM proteins: important players in differentiation and disease
Q88669854PRDM1 silences stem cell-related genes and inhibits proliferation of human colon tumor organoids
Q47162986PRDM1/BLIMP1 is widely distributed to the nascent fetal-placental interface in the mouse gastrula
Q34545167PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency
Q91608202PRDM14 and BLIMP1 control the development of chicken primordial germ cells
Q34602255PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos
Q50420430Pediatric Germ Cell Tumors: A Developmental Perspective.
Q50548663Persistent Requirement and Alteration of the Key Targets of PRDM1 During Primordial Germ Cell Development in Mice.
Q34742136Perspectives of germ cell development in vitro in mammals
Q37579582Phenotype and function of protective, CD4-independent CD8 T cell memory
Q26772258Physiologic Course of Female Reproductive Function: A Molecular Look into the Prologue of Life
Q42955017Pluripotency takes off without Blimp1.
Q37776444Pluripotent Stem Cells: Origin, Maintenance and Induction
Q26823737Poised chromatin in the mammalian germ line
Q33648204Posterior localization of ApVas1 positions the preformed germ plasm in the sexual oviparous pea aphid Acyrthosiphon pisum.
Q38682042Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity
Q96613307Prdm1 overexpression causes a photoreceptor fate-shift in nascent, but not mature, bipolar cells
Q39045174Prdm1- and Sox6-mediated transcriptional repression specifies muscle fibre type in the zebrafish embryo
Q28591136Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation
Q37080808Prdm1a directly activates foxd3 and tfap2a during zebrafish neural crest specification
Q35054101Prdm6 is essential for cardiovascular development in vivo
Q28595065Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice
Q26766159Primordial Germ Cell Specification and Migration
Q26774606Primordial Germ Cells: Current Knowledge and Perspectives
Q50980266Primordial germ cell differentiation of nuclear transfer embryonic stem cells using surface modified electroconductive scaffolds.
Q34436937Primordial germ cell specification: a context-dependent cellular differentiation event [corrected].
Q33518562Primordial germ cell-like cells differentiated in vitro from skin-derived stem cells
Q22065789Primordial germ cells in mice
Q26796680Primordial germ cells: the first cell lineage or the last cells standing?
Q47132095Principles for the regulation of multiple developmental pathways by a versatile transcriptional factor, BLIMP1.
Q41193415Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency
Q34975362Production of offspring from a germline stem cell line derived from neonatal ovaries
Q91558589Programmed DNA elimination of germline development genes in songbirds
Q42371685Progress and future prospect of in vitro spermatogenesis
Q50594691Protein arginine methyltransferase 5 (Prmt5) is required for germ cell survival during mouse embryonic development.
Q33311620Proximal visceral endoderm and extraembryonic ectoderm regulate the formation of primordial germ cell precursors
Q34302826Purification of oogonial stem cells from adult mouse and human ovaries: an assessment of the literature and a view toward the future
Q37133634Rebuilding pluripotency from primordial germ cells
Q38733861Reconstitution in vitro of the entire cycle of the mouse female germ line
Q57197766Recurrence of perinatal lethal osteogenesis imperfecta in sibships: Parsing the risk between parental mosaicism for dominant mutations and autosomal recessive inheritance
Q42751372Redundant roles of PRDM family members in zebrafish craniofacial development
Q56142920Regulation of Maternal mRNAs in Early Development
Q34517964Regulation of male sex determination: genital ridge formation and Sry activation in mice
Q42429601Regulatory analysis of the C. elegans genome with spatiotemporal resolution
Q34510690Reinterpretation of evidence advanced for neo-oogenesis in mammals, in terms of a finite oocyte reserve
Q37247886RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1.
Q38516157Repression of somatic cell fate in the germline
Q28078353Reprogramming of germ cells into pluripotency
Q33379605Reprogramming primordial germ cells into pluripotent stem cells
Q39994213Requirement of Oct3/4 function for germ cell specification
Q38039002Resetting epigenetic signatures to induce somatic cell reprogramming
Q91952819Retinoic acid signaling in regulation of meiosis during embryonic development in mice
Q40720742Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells
Q34243070Role of polycomb group protein cbx2/m33 in meiosis onset and maintenance of chromosome stability in the Mammalian germline
Q57167334Roles of microRNAs in mammalian reproduction: from the commitment of germ cells to peri-implantation embryos
Q38726498SET domain-containing protein 5 is required for expression of primordial germ cell specification-associated genes in murine embryonic stem cells
Q34042884SOX17 is a critical specifier of human primordial germ cell fate
Q37565051SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate
Q97561767SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation
Q35783056STELLA-positive subregions of the primitive streak contribute to posterior tissues of the mouse gastrula
Q24309228SUMOylation of Blimp-1 promotes its proteasomal degradation
Q90476044Segregation of the mouse germline and soma
Q37243784Selective de-repression of germ cell-specific genes in mouse embryonic fibroblasts in a permissive epigenetic environment
Q37385497Self-renewing epiblast stem cells exhibit continual delineation of germ cells with epigenetic reprogramming in vitro
Q30176410Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates
Q48565926Sequences analyses and expression profiles in tissues and embryos of Japanese flounder (Paralichthys olivaceus) PRDM1.
Q35151140Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cells
Q35877654Sex Specification and Heterogeneity of Primordial Germ Cells in Mice
Q34005745Signaling pathways in spermatogonial stem cells and their disruption by toxicants
Q34110579Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells.
Q37077826Single-cell cDNA high-density oligonucleotide microarray analysis: detection of individual cell types and properties in complex biological processes
Q36863517Small SSEA-4-positive cells from human ovarian cell cultures: related to embryonic stem cells and germinal lineage?
Q42001929Sox2 modulates the function of two distinct cell lineages in mouse skin
Q38940310Specification and epigenetic programming of the human germ line
Q26822975Specifying and protecting germ cell fate
Q42144106Stage-Specific Demethylation in Primordial Germ Cells Safeguards against Precocious Differentiation.
Q31027730Stage-specific germ-cell marker genes are expressed in all mouse pluripotent cell types and emerge early during induced pluripotency
Q33986204Stem cell potential of the mammalian gonad
Q22122316Stem cells: Egg engineers
Q102075513Stem-cell-based embryo models for fundamental research and translation
Q40484534Stochastic specification of primordial germ cells from mesoderm precursors in axolotl embryos.
Q37581642Suppression of the SOX2 neural effector gene by PRDM1 promotes human germ cell fate in embryonic stem cells
Q33688750Systematic identification and comparison of expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in mouse germline stem cells
Q39525588TCam-2 seminoma cell line exhibits characteristic foetal germ cell responses to TGF-beta ligands and retinoic acid
Q101409802TGF-β1-regulated miR-3691-3p targets E2F3 and PRDM1 to inhibit prostate cancer progression
Q35224542Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
Q44726015Targeted expression in zebrafish primordial germ cells by Cre/loxP and Gal4/UAS systems.
Q35417181Testicular somatic cells, not gonocytes, are the major source of functional activin A during testis morphogenesis
Q50664884The Blimp-1 gene regulatory region directs EGFP expression in multiple hematopoietic lineages and testis in mice.
Q33794960The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.
Q39684525The Formation and Migration of Primordial Germ Cells in Mouse and Man.
Q28854377The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo
Q28085672The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond
Q36760326The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse.
Q35205001The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice
Q27313398The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification
Q38975123The biology of germ cell tumors in disorders of sex development
Q37206451The biology of infertility: research advances and clinical challenges
Q28655577The biology of the germ line in echinoderms
Q33291750The cis-regulatory logic of the mammalian photoreceptor transcriptional network
Q36081972The germ cell determinant Blimp1 is not required for derivation of pluripotent stem cells
Q34769303The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland
Q35801383The lesser known story of X chromosome reactivation: a closer look into the reprogramming of the inactive X chromosome
Q37385514The mammalian ovary from genesis to revelation
Q41997156The molecular characterization of porcine egg precursor cells.
Q34620075The murine allantois: emerging paradigms in development of the mammalian umbilical cord and its relation to the fetus
Q38010006The reciprocal relationship between primordial germ cells and pluripotent stem cells
Q37513681The rise of testicular germ cell tumours: the search for causes, risk factors and novel therapeutic targets.
Q37874665The role of BLIMP1 and its putative downstream target TFAP2C in germ cell development and germ cell tumours.
Q36921155The transcriptional repressor Blimp1 is expressed in rare luminal progenitors and is essential for mammary gland development
Q96131692The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice
Q28512957The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes
Q33402914The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development
Q34506971Time-lapse analysis reveals different modes of primordial germ cell migration in the medaka Oryzias latipes
Q37528278Tools for the genetic analysis of germ cells
Q34963433Transcription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice
Q61783468Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance
Q37439855Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties
Q37681231Transgenerational epigenetics in the germline cycle of Caenorhabditis elegans
Q40075894Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory
Q37068357Two-step oligoclonal development of male germ cells
Q37763939Use of human embryonic stem cell-based models for male reproductive toxicity screening
Q27335571Whole-mount MeFISH: a novel technique for simultaneous visualization of specific DNA methylation and protein/RNA expression
Q39305548Why are hematopoietic stem cells so 'sexy'? on a search for developmental explanation.
Q28506015Widespread but tissue-specific patterns of interferon-induced transmembrane protein 3 (IFITM3, FRAGILIS, MIL-1) in the mouse gastrula
Q38786073Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties
Q33319283X chromosome activity in mouse XX primordial germ cells
Q30833162X chromosome reactivation initiates in nascent primordial germ cells in mice
Q28076597Zebrafish Germ Cell Tumors
Q37598667Zebrafish models of germ cell tumor
Q52615339[Carcinoma in situ of the testis: predisposition, evolution and early detection].
Q41827449prdm1a Regulates sox10 and islet1 in the development of neural crest and Rohon-Beard sensory neurons

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