| scholarly article | Q13442814 |
| retracted paper | Q45182324 |
| P356 | DOI | 10.1093/HMG/DDU734 |
| P698 | PubMed publication ID | 25561692 |
| P50 | author | Craig Magee | Q47503982 |
| P2093 | author name string | James P Allen | |
| Christian L Lorson | |||
| Philip J Young | |||
| Chenda O Seng | |||
| P2860 | cites work | The Gemin5 protein of the SMN complex identifies snRNAs | Q24297645 |
| Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis | Q24300255 | ||
| Functional organization of the Sm core in the crystal structure of human U1 snRNP | Q24309502 | ||
| An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs | Q24311843 | ||
| The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins | Q24316085 | ||
| Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly | Q24319038 | ||
| The survival motor neuron protein forms soluble glycine zipper oligomers | Q24600623 | ||
| PHENIX: a comprehensive Python-based system for macromolecular structure solution | Q24654617 | ||
| PROCHECK: a program to check the stereochemical quality of protein structures | Q26778411 | ||
| SMN tudor domain structure and its interaction with the Sm proteins | Q27629094 | ||
| High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues | Q27640685 | ||
| Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution | Q27654469 | ||
| The neurobiology of childhood spinal muscular atrophy. | Q41489423 | ||
| Mutation update of spinal muscular atrophy in Spain: molecular characterization of 745 unrelated patients and identification of four novel mutations in the SMN1 gene. | Q44669542 | ||
| Analysis of point mutations in the SMN1 gene in SMA patients bearing a single SMN1 copy. | Q45867775 | ||
| An exonic enhancer is required for inclusion of an essential exon in the SMA-determining gene SMN | Q73295491 | ||
| A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems | Q73297574 | ||
| SMN oligomerization defect correlates with spinal muscular atrophy severity | Q74557706 | ||
| Gemin2 plays an important role in stabilizing the survival of motor neuron complex | Q79794565 | ||
| SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN | Q81385781 | ||
| Structural basis of assembly chaperone- mediated snRNP formation | Q27683788 | ||
| Coot: model-building tools for molecular graphics | Q27860505 | ||
| SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model | Q27861069 | ||
| The CCP4 suite: programs for protein crystallography | Q27861090 | ||
| Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis | Q28115894 | ||
| The spliceosome: design principles of a dynamic RNP machine | Q28131809 | ||
| Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy | Q28137718 | ||
| The exon 2b region of the spinal muscular atrophy protein, SMN, is involved in self-association and SIP1 binding | Q28138530 | ||
| The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies | Q28140527 | ||
| SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets | Q28199238 | ||
| LSm proteins form heptameric rings that bind to RNA via repeating motifs | Q28264182 | ||
| Regulation of SMN protein stability | Q28304878 | ||
| Identification and characterization of a spinal muscular atrophy-determining gene | Q29547495 | ||
| A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy | Q29617367 | ||
| Practically useful: what the Rosetta protein modeling suite can do for you | Q30386768 | ||
| Inactivation of the SMN complex by oxidative stress | Q33355418 | ||
| Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick? | Q33785933 | ||
| Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). | Q33905442 | ||
| Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPs | Q34230914 | ||
| Essential role for the SMN complex in the specificity of snRNP assembly | Q34529450 | ||
| Splicing in disease: disruption of the splicing code and the decoding machinery | Q34582131 | ||
| Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number | Q35250646 | ||
| SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins. | Q35641208 | ||
| Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. | Q36602121 | ||
| Chaperoning ribonucleoprotein biogenesis in health and disease | Q36777301 | ||
| Evolution of an RNP assembly system: a minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster | Q36786870 | ||
| snRNAs contain specific SMN-binding domains that are essential for snRNP assembly | Q37012661 | ||
| Evolutionary diversification of the Sm family of RNA-associated proteins | Q37238158 | ||
| SMN and Gemins: 'we are family' … or are we?: insights into the partnership between Gemins and the spinal muscular atrophy disease protein SMN. | Q37800873 | ||
| Deciphering arginine methylation: Tudor tells the tale. | Q37931616 | ||
| Tudor: a versatile family of histone methylation 'readers'. | Q38137526 | ||
| The intriguing case of motor neuron disease: ALS and SMA come closer. | Q38164393 | ||
| ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN. | Q39150934 | ||
| Mislocalised FUS mutants stall spliceosomal snRNPs in the cytoplasm | Q39176818 | ||
| Molecular and functional analysis of intragenic SMN1 mutations in patients with spinal muscular atrophy. | Q40484524 | ||
| Tudor domains in proteins that interact with RNA. | Q41361779 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2138-46 | |
| P577 | publication date | 2015-04-15 | |
| P1433 | published in | Human Molecular Genetics | Q2720965 |
| P1476 | title | The SMN structure reveals its crucial role in snRNP assembly | |
| P478 | volume | 24 |
| Q42289539 | A critical examination of the recently reported crystal structures of the human SMN protein. |
| Q93178436 | Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions |
| Q36389484 | How do SMA-linked mutations of SMN1 lead to structural/functional deficiency of the SMA protein? |
| Q51636016 | Mutation Spectrum of the Survival of Motor Neuron 1 and Functional Analysis of Variants in Chinese Spinal Muscular Atrophy. |
| Q48646595 | Retraction notice: the SMN structure reveals its crucial role in snRNP assembly |
| Q47885235 | SMN regulation in SMA and in response to stress: new paradigms and therapeutic possibilities. |
| Q38684609 | Seeing but not believing: the structure of glycerol dehydrogenase initially assumed to be the structure of a survival protein from Salmonella typhimurium |
| Q36613857 | Spatial regulation of cytoplasmic snRNP assembly at the cellular level |
| Q30398280 | Structure determination of contaminant proteins using the MarathonMR procedure |
| Q30008890 | Targeting the SH3 domain of human osteoclast-stimulating factor with rationally designed peptoid inhibitors |
| Q46255967 | The science is in the data. |
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