scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Niels Behrendt | Q57167310 |
P2093 | author name string | Niels Behrendt | |
P2860 | cites work | The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells | Q47859760 |
Characterization of a novel member of the macrophage mannose receptor type C lectin family | Q48060936 | ||
Differential binding of urokinase and peptide antagonists to the urokinase receptor: evidence from characterization of the receptor in four primate species | Q48365509 | ||
Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia. | Q51723107 | ||
LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation | Q52478181 | ||
Structural analysis of the interaction between urokinase-type plasminogen activator and its receptor: a potential target for anti-invasive cancer therapy | Q55952245 | ||
Physiological consequences of loss of plasminogen activator gene function in mice | Q59069678 | ||
A urokinase receptor-associated protein with specific collagen binding properties | Q22011054 | ||
Genes expressed in human tumor endothelium | Q24290105 | ||
An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator | Q24316221 | ||
A novel, specific pro-urokinase complex on monocyte-like cells, detected by transglutaminase-catalyzed cross-linking | Q24318514 | ||
Identification and characterization of the endocytic transmembrane glycoprotein Endo180 as a novel collagen receptor | Q24322753 | ||
Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes | Q24532196 | ||
Direct binding of occupied urokinase receptor (uPAR) to LDL receptor-related protein is required for endocytosis of uPAR and regulation of cell surface urokinase activity | Q24633333 | ||
The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes | Q24678932 | ||
Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction | Q24683196 | ||
A cysteine-rich domain of the "mannose" receptor mediates GalNAc-4-SO4 binding | Q24685889 | ||
Crystal structure of the cysteine-rich domain of mannose receptor complexed with a sulfated carbohydrate ligand | Q27622086 | ||
Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor | Q27622317 | ||
Gelatin-binding region of human matrix metalloproteinase-2: solution structure, dynamics, and function of the COL-23 two-domain construct | Q27631337 | ||
Structure of a C-type mannose-binding protein complexed with an oligosaccharide | Q27642164 | ||
Structure of the Calcium-Dependent Lectin Domain from a Rat Mannose-Binding Protein Determined by MAD Phasing | Q27643496 | ||
Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins | Q27729364 | ||
Structure of a soluble, glycosylated form of the human complement regulatory protein CD59 | Q27729400 | ||
Lipid rafts and signal transduction | Q28131735 | ||
Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells | Q28142061 | ||
Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease | Q28144714 | ||
Human and mouse proteases: a comparative genomic approach | Q28184208 | ||
The mannose receptor family | Q28201143 | ||
The urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motility | Q28212178 | ||
Serpins and other covalent protease inhibitors | Q28212469 | ||
Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598 | Q28253229 | ||
Role of vitronectin and its receptors in haemostasis and vascular remodeling | Q28272554 | ||
Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro | Q28282164 | ||
Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L | Q28290438 | ||
The receptor for urokinase plasminogen activator is present in plasma from healthy donors and elevated in patients with paroxysmal nocturnal haemoglobinuria | Q40993621 | ||
A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake | Q41007686 | ||
Three-dimensional interplay among the ligand-binding domains of the urokinase-plasminogen-activator-receptor-associated protein, Endo180. | Q41008420 | ||
Expression of the receptor for urokinase-type plasminogen activator in normal and neoplastic blood cells and hematopoietic tissue | Q41011037 | ||
Phagocytosis and intracellular digestion of collagen, its role in turnover and remodelling. | Q41077587 | ||
A soluble form of the glycolipid-anchored receptor for urokinase-type plasminogen activator is secreted from peripheral blood leukocytes from patients with paroxysmal nocturnal hemoglobinuria | Q41085646 | ||
Domain interplay in the urokinase receptor. Requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains. | Q41168123 | ||
Regulation of integrin function by the urokinase receptor | Q41168373 | ||
Very Low Density Lipoprotein Receptor Binds and Mediates Endocytosis of Urokinase-type Plasminogen Activator-Type-1 Plasminogen Activator Inhibitor Complex | Q41301968 | ||
The receptor for urokinase-type plasminogen activator is expressed by keratinocytes at the leading edge during re-epithelialization of mouse skin wounds | Q41475599 | ||
The urokinase-type plasminogen activator system in cancer metastasis: A review | Q41522331 | ||
Ultrastructural localization of plasma membrane-associated urokinase-type plasminogen activator at focal contacts | Q41543313 | ||
Structural requirements for glycosyl-phosphatidylinositol-anchor attachment in the cellular receptor for urokinase plasminogen activator | Q41606805 | ||
ECM and cell surface proteolysis: regulating cellular ecology | Q41656253 | ||
Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor | Q41669188 | ||
Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction | Q41787217 | ||
Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin | Q41812511 | ||
Two alternatively spliced mouse urokinase receptor mRNAs with different histological localization in the gastrointestinal tract | Q41877722 | ||
Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes | Q42163142 | ||
Phosphorylation of human pro-urokinase on Ser138/303 impairs its receptor-dependent ability to promote myelomonocytic adherence and motility | Q42209596 | ||
Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling | Q42478267 | ||
Cancer cell expression of urokinase-type plasminogen activator receptor mRNA in squamous cell carcinomas of the skin | Q42500699 | ||
Functional overlap between two classes of matrix-degrading proteases in wound healing | Q42679931 | ||
The C-type lectin receptor Endo180 displays internalization and recycling properties distinct from other members of the mannose receptor family | Q42813761 | ||
Urokinase-catalysed cleavage of the urokinase receptor requires an intact glycolipid anchor. | Q43000092 | ||
The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation. | Q43002806 | ||
An extended conformation of the macrophage mannose receptor | Q43560257 | ||
Cutting edge: evidence for a signaling partnership between urokinase receptors (CD87) and L-selectin (CD62L) in human polymorphonuclear neutrophils | Q43567106 | ||
The urokinase plasminogen activator receptor-associated protein/endo180 is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis | Q43764719 | ||
Activation of pro-urokinase by the human T cell-associated serine proteinase HuTSP-1. | Q43933765 | ||
Inhibition of receptor-dependent urokinase signaling by specific Ser to Glu substitutions. | Q43944113 | ||
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV. | Q44732185 | ||
Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent anthrax toxin | Q44779601 | ||
Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice | Q45754755 | ||
Urokinase but not tissue plasminogen activator mediates arterial neointima formation in mice | Q45884112 | ||
Optimal subsite occupancy and design of a selective inhibitor of urokinase. | Q45940894 | ||
Urokinase receptor is up-regulated in endothelial cells and macrophages associated with fibrinoid deposits in the human placenta | Q47800906 | ||
Kinetics of reciprocal pro-urokinase/plasminogen activation--stimulation by a template formed by the urokinase receptor bound to poly(D-lysine). | Q47853148 | ||
Human bladder cancer invasion model using rat bladder in vitro and its use to test mechanisms and therapeutic inhibitors of invasion | Q28350937 | ||
A plasma kallikrein-dependent plasminogen cascade required for adipocyte differentiation | Q28357136 | ||
A functional overlap of plasminogen and MMPs regulates vascularization during placental development | Q28507163 | ||
Matrix metalloproteinases: effectors of development and normal physiology | Q28679038 | ||
Inhibition of cell surface mediated plasminogen activation by a monoclonal antibody against alpha-Enolase | Q28910334 | ||
How matrix metalloproteinases regulate cell behavior | Q29620360 | ||
The very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro | Q30303631 | ||
Epidermal growth factor receptor-dependent and -independent cell-signaling pathways originating from the urokinase receptor | Q30310205 | ||
Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility | Q30471919 | ||
Association of a protease (plasminogen activator) with a specific membrane fraction isolated from transformed cells | Q30494593 | ||
Imaging proteolysis by living human glioma cells | Q30703032 | ||
Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly [...] | Q31960282 | ||
Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells | Q32063287 | ||
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis | Q33744153 | ||
Proteolysis and cell migration: creating a path? | Q33744936 | ||
A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity. | Q33887878 | ||
Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1. | Q33948206 | ||
Ligneous conjunctivitis | Q33967011 | ||
The plasminogen activation system in tumor growth, invasion, and metastasis | Q34008816 | ||
The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R. | Q34009345 | ||
The urokinase receptor is required for human monocyte chemotaxis in vitro | Q34137611 | ||
uPAR: a versatile signalling orchestrator | Q34162183 | ||
The urokinase receptor associated protein (uPARAP/endo180): a novel internalization receptor connected to the plasminogen activation system | Q34286244 | ||
Potent antitumor activity of a urokinase-activated engineered anthrax toxin | Q34470439 | ||
Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis | Q34489359 | ||
Matrix metalloproteinases in tumor invasion: role for cell migration | Q34657461 | ||
Role of plasminogen activator-plasmin system in tumor angiogenesis | Q35123778 | ||
Pericellular cathepsin B and malignant progression | Q35144589 | ||
Urokinase-type plasminogen activator (uPA) and its receptor (uPAR): development of antagonists of uPA/uPAR interaction and their effects in vitro and in vivo | Q35181139 | ||
Molecular and functional interdependence of the urokinase-type plasminogen activator system with integrins | Q35219000 | ||
High-affinity urokinase receptor antagonists identified with bacteriophage peptide display | Q35617966 | ||
A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase | Q36211634 | ||
The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type | Q36216545 | ||
Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants | Q36220582 | ||
Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells | Q36234366 | ||
Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release? | Q36237406 | ||
Receptor-independent role of urokinase-type plasminogen activator in pericellular plasmin and matrix metalloproteinase proteolysis during vascular wound healing in mice | Q36254926 | ||
uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion | Q36323184 | ||
GPI-anchored uPAR requires Endo180 for rapid directional sensing during chemotaxis. | Q36323266 | ||
Prevention of metastasis by inhibition of the urokinase receptor | Q36332391 | ||
The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae | Q36382514 | ||
Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo. | Q36401755 | ||
Chemical modification of the urokinase-type plasminogen activator and its receptor using tetranitromethane. Evidence for the involvement of specific tyrosine residues in both molecules during receptor-ligand interaction | Q36679850 | ||
p180, a novel recycling transmembrane glycoprotein with restricted cell type expression | Q36710108 | ||
Isolation and characterization of multiple isoforms of the rat urokinase receptor in osteoblasts | Q36762530 | ||
Differences in intracellular distribution of plasminogen activator in growing, confluent, and transformed 3T3 cells | Q37311345 | ||
Generation and characterization of urokinase receptor-deficient mice | Q37351869 | ||
The urokinase receptor (CD87) facilitates CD11b/CD18-mediated adhesion of human monocytes | Q37354367 | ||
Binding of high molecular weight kininogen to human endothelial cells is mediated via a site within domains 2 and 3 of the urokinase receptor | Q37372571 | ||
Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes | Q37524689 | ||
Urokinase-type plasminogen activator is effective in fibrin clearance in the absence of its receptor or tissue-type plasminogen activator | Q37561638 | ||
Plasminogen activator inhibitors: hormonally regulated serpins | Q37807999 | ||
Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells | Q38288786 | ||
Multifunctional activity of the extracellular domain of the M-type (180 kDa) membrane receptor for secretory phospholipases A2. | Q38290493 | ||
Peptide-derived antagonists of the urokinase receptor. affinity maturation by combinatorial chemistry, identification of functional epitopes, and inhibitory effect on cancer cell intravasation | Q38296358 | ||
The gelatin-binding site of human 72 kDa type IV collagenase (gelatinase A). | Q38310500 | ||
Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis | Q38317155 | ||
Sequences within domain II of the urokinase receptor critical for differential ligand recognition | Q38354388 | ||
Characterization of sugar binding by the mannose receptor family member, Endo180. | Q38361627 | ||
Dimerization controls the lipid raft partitioning of uPAR/CD87 and regulates its biological functions | Q40240320 | ||
Distribution of Endo180 receptor and ligand in developing articular cartilage. | Q40603509 | ||
Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxins | Q40683497 | ||
Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin alpha Mbeta 2 as well as by the urokinase receptor regulates cell adhesion and migration | Q40695132 | ||
The cleavage of the urokinase receptor regulates its multiple functions | Q40701611 | ||
Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection | Q40867377 | ||
Identification of a urokinase receptor-integrin interaction site. Promiscuous regulator of integrin function | Q40890085 | ||
Polysulfated heparinoids selectively inactivate heparin-binding angiogenesis factors | Q40901139 | ||
Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor | Q40915798 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | membrane protein | Q423042 |
P304 | page(s) | 103-136 | |
P577 | publication date | 2004-02-01 | |
P1433 | published in | Biological Chemistry | Q4914948 |
P1476 | title | The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodeling | |
P478 | volume | 385 |
Q39999171 | A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor |
Q35213422 | A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180 |
Q40302526 | A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth |
Q33546389 | A role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion |
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Q24306849 | Endosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassembly |
Q37399542 | Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice |
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Q53541672 | Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation. |
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Q37181208 | Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation |
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