Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder

scientific article

Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NBD.2015.06.018
P698PubMed publication ID26143616
P5875ResearchGate publication ID279635449

P50authorStefania TrazziQ41900410
Elisabetta CianiQ56550093
Marianna De FranceschiQ57307312
P2093author name stringClaudia Fuchs
Rocchina Viggiano
Roberto Rimondini
Renata Bartesaghi
P407language of work or nameEnglishQ1860
P921main subjectCDKL5 deficiency disorderQ40739448
P304page(s)298-310
P577publication date2015-10-01
P1433published inNeurobiology of DiseaseQ15716606
P1476titleInhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder
P478volume82

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cites work (P2860)
Q28079929A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.
Q53828453Comprehensive behavioral analysis of the Cdkl5 knockout mice revealed significant enhancement in anxiety- and fear-related behaviors and impairment in both acquisition and long-term retention of spatial reference memory.
Q64939210Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Clinical Review.
Q38736520Depletion of the Fragile X Mental Retardation Protein in Embryonic Stem Cells Alters the Kinetics of Neurogenesis
Q64078571Functional and Structural Impairments in the Perirhinal Cortex of a Mouse Model of CDKL5 Deficiency Disorder Are Rescued by a TrkB Agonist
Q48599692HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder
Q55436457Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder.
Q89460115Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons
Q39103694Lack of Cdkl5 Disrupts the Organization of Excitatory and Inhibitory Synapses and Parvalbumin Interneurons in the Primary Visual Cortex.
Q48183034Loss of CDKL5 in Glutamatergic Neurons Disrupts Hippocampal Microcircuitry and Leads to Memory Impairment in Mice.
Q47661198Mice lacking cyclin-dependent kinase-like 5 manifest autistic and ADHD-like behaviors
Q91678331Molecular and Synaptic Bases of CDKL5 Disorder
Q33752190Molecular and genetic insights into an infantile epileptic encephalopathy - CDKL5 disorder
Q33762246Searching for biomarkers of CDKL5 disorder: early-onset visual impairment in CDKL5 mutant mice
Q89596064The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo

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