MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells

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MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/STEM.1108
P8608Fatcat IDrelease_oxpncndgyvce7p6teig4lp5m7q
P3181OpenCitations bibliographic resource ID1292285
P698PubMed publication ID22511267
P5875ResearchGate publication ID224284583

P50authorZuzana HolubcováQ56524570
Marek MrázQ60566897
P2093author name stringMarek Mraz
Sarka Pospisilova
Ales Hampl
Petr Dvorak
Karla Plevova
Vladimir Vinarsky
Tomas Barta
Josef Jaros
Zuzana Holubcova
Dasa Dolezalova
P2860cites workThe miR-302-367 cluster as a potential stemness regulator in ESCsQ37379733
miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expressionQ38498353
The Nodal inhibitor Lefty is negatively modulated by the microRNA miR-302 in human embryonic stem cells.Q39602807
Human embryonic stem cells suffer from centrosomal amplification.Q39641991
Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo.Q39726753
MicroRNA-125b is a novel negative regulator of p53.Q39871732
A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cellsQ40228726
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phaseQ40232134
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors.Q42459454
A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiationQ42578044
An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesisQ44660997
p53 is required for etoposide-induced apoptosis of human embryonic stem cellsQ46042211
Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cellsQ47969653
miChip: an array-based method for microRNA expression profiling using locked nucleic acid capture probesQ57397529
Bioconductor: open software development for computational biology and bioinformaticsQ21194861
MicroRNA and gene expression patterns in the differentiation of human embryonic stem cellsQ21245471
Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cellsQ24323720
Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiationQ24563808
Significance analysis of microarrays applied to the ionizing radiation responseQ24606608
MicroRNAs: target recognition and regulatory functionsQ24609584
Normalization of cDNA microarray dataQ28181692
Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain developmentQ28261372
A microRNA component of the p53 tumour suppressor networkQ28305330
MicroRNA regulation of DNA repair gene expression in hypoxic stressQ28306694
miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalitiesQ28307338
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cellsQ29615089
Linking the p53 tumour suppressor pathway to somatic cell reprogrammingQ29616507
Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotencyQ29616797
The p53 pathway: positive and negative feedback loopsQ29617535
Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferationQ33382062
Survival responses of human embryonic stem cells to DNA damageQ34078474
miR-221/222 suppression protects against endoplasmic reticulum stress-induced apoptosis via p27(Kip1)- and MEK/ERK-mediated cell cycle regulationQ34125608
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damageQ34453891
Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.Q34784150
The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selectionQ34977214
MicroRNA isolation and stability in stored RNA samplesQ35004301
Characterization of microRNAs involved in embryonic stem cell statesQ35082773
Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cellsQ35924505
MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progressionQ36498054
Cell cycle control of embryonic stem cellsQ36672102
Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoterQ36949730
G1 to S phase cell cycle transition in somatic and embryonic stem cells.Q37220180
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
DNA damageQ5205747
human embryonic stem cellQ59626782
P304page(s)1362-72
P577publication date2012-07-01
P1433published inStem CellsQ15724411
P1476titleMicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells
P478volume30

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cites work (P2860)
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