Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1-7) in regulation of cardiovascular function

scientific article

Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1-7) in regulation of cardiovascular function is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.00618.2005
P3181OpenCitations bibliographic resource ID1308153
P698PubMed publication ID16055515

P2093author name stringJewell A Jessup
Carlos M Ferrario
Aaron J Trask
P2860cites workA novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9Q24290169
The mas oncogene encodes an angiotensin receptorQ24298473
Angiotensin (1-7) re-establishes impulse conduction in cardiac muscle during ischaemia-reperfusion. The role of the sodium pumpQ24299365
Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolismQ24300310
Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexinsQ24321922
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor MasQ24680069
ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysisQ27643059
Network biology: understanding the cell's functional organizationQ27861027
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidaseQ28115041
Angiotensin-converting enzyme 2 is an essential regulator of heart functionQ28205840
Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzymeQ28216431
ACEH/ACE2 is a novel mammalian metallocarboxypeptidase and a homologue of angiotensin-converting enzyme insensitive to ACE inhibitorsQ28218830
The mas oncogene as a neural peptide receptor: expression, regulation and mechanism of actionQ28249627
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injuryQ28260798
Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptorQ28573659
Cardiac Angiotensin-(1-7) in Ischemic CardiomyopathyQ79096678
Ac-SDKP reverses cardiac fibrosis in rats with renovascular hypertensionQ79214001
Renal ACE2 expression in human kidney diseaseQ80990190
Genome-wide scan for Japanese familial intracranial aneurysms: linkage to several chromosomal regionsQ81072729
ACE and ACE2: a tale of two enzymesQ81320236
Myocardial infarction increases ACE2 expression in rat and humansQ81656120
Pathways for angiotensin-(1---7) metabolism in pulmonary and renal tissuesQ73127508
Hypothesis: ACE2 modulates blood pressure in the mammalian organismQ73167489
Evidence that prostaglandins mediate the antihypertensive actions of angiotensin-(1-7) during chronic blockade of the renin-angiotensin systemQ73989986
Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin systemQ74132679
Metabolism of angiotensin-(1-7) by angiotensin-converting enzymeQ74132686
Vasodepressor actions of angiotensin-(1-7) unmasked during combined treatment with lisinopril and losartanQ74165944
Differential actions of renal ischemic injury on the intrarenal angiotensin systemQ74346345
N-domain-specific substrate and C-domain inhibitors of angiotensin-converting enzyme: angiotensin-(1-7) and keto-ACEQ74423538
Angiotensin-(1-7) improves the post-ischemic function in isolated perfused rat heartsQ74758710
Converting enzyme determines plasma clearance of angiotensin-(1-7)Q77310280
Differential response of angiotensin peptides in the urine of hypertensive animalsQ77425675
Angiotensin-(1-7) reduces smooth muscle growth after vascular injuryQ77945580
Angiotensin-(1-7) in normal and preeclamptic pregnancyQ78568866
Slow ventricular conduction in mice heterozygous for a connexin43 null mutationQ28591559
Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient miceQ28593966
The renin-angiotensin system: peptides and enzymes beyond angiotensin IIQ28645960
Angiotension-(1-7) and antihypertensive mechanismsQ33536947
Release of vasopressin from the rat hypothalamo-neurohypophysial system by angiotensin-(1-7) heptapeptideQ33579511
Angiotensin-(1-7): an update.Q34019825
The adipose tissue as a source of vasoactive factorsQ34342326
The angiotensin-converting enzyme gene family: genomics and pharmacologyQ34586915
Bradykinin, angiotensin-(1-7), and ACE inhibitors: how do they interact?Q35099121
Exploring the structure and function of zinc metallopeptidases: old enzymes and new discoveriesQ35139444
ACE2, a new regulator of the renin-angiotensin systemQ35756519
Novel aspects of the renal renin-angiotensin system: angiotensin-(1-7), ACE2 and blood pressure regulation.Q35833603
Enhanced expression of Ang-(1-7) during pregnancyQ35845564
Is angiotensin II made inside or outside of the cell?Q36062239
Angiotensin-[1-7]: evidence for novel actions in the brainQ36631113
Hypertension and coronary artery disease. Can the chain be broken?Q37103647
Angiotensin-(1-7): a new hormone of the angiotensin systemQ37450381
A comparison of the properties and enzymatic activities of three angiotensin processing enzymes: angiotensin converting enzyme, prolyl endopeptidase and neutral endopeptidase 24.11.Q40853474
Active fragments of angiotensin II: enzymatic pathways of synthesis and biological effectsQ41364638
Counterregulatory actions of angiotensin-(1-7).Q41607078
Pressor and reflex sensitivity is altered in spontaneously hypertensive rats treated with angiotensin-(1-7).Q41659395
Evidence for a functional cardiac interaction between losartan and angiotensin-(1-7) receptors revealed by orthostatic tilting test in ratsQ42016830
Effects of angiotensin analogues and angiotensin receptor antagonists on paraventricular neuronesQ42086362
News about ACE, or, the separate lives of "Siamese twin" domainsQ42356218
Molecular mechanisms of inhibition of vascular growth by angiotensin-(1-7).Q42447014
Single mutations at Asn295 and Leu305 in the cytoplasmic half of transmembrane alpha-helix domain 7 of the AT1 receptor induce promiscuous agonist specificity for angiotensin II fragments: a pseudo-constitutive activityQ42478506
Molecular cloning, mRNA expression and chromosomal localization of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2).Q42690932
Downregulation of the AT1A receptor by pharmacologic concentrations of Angiotensin-(1-7).Q43573763
Angiotensin-(1-7) downregulates the angiotensin II type 1 receptor in vascular smooth muscle cellsQ43576527
Angiotensin-(1-7): cardioprotective effect in myocardial ischemia/reperfusionQ43744776
Angiotensin(1-7) potentiates bradykinin-induced vasodilatation in man.Q43777437
Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivoQ43830188
The antithrombotic effect of angiotensin-(1-7) closely resembles that of losartanQ43907228
Urinary vasodilator and vasoconstrictor angiotensins during menstrual cycle, pregnancy, and lactationQ43912171
Angiotensin-(1-7) stimulates oxidative stress in rat kidneyQ44016672
Effects of omapatrilat on the renin-angiotensin system in salt-sensitive hypertensionQ44034807
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).Q44201695
Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR.Q44249678
Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy.Q44353743
Angiotensin-(1-7): a novel peptide in the ovary.Q44405108
Characterization of angiotensin-(1–7) receptor subtype in mesenteric arteriesQ44430740
Effects of truncated angiotensins in humans after double blockade of the renin systemQ44517333
Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2.Q44592757
Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptorsQ44790566
Angiotensin type-1 receptor blockade increases ACE 2 expression in the heartQ44790573
Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in ratsQ44811232
The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubulesQ45092010
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpressionQ45115249
Losartan increases bradykinin levels in hypertensive humansQ45227736
Myocardial infarction increases ACE2 expression in rat and humans.Q45238600
Pharmacological concentration of angiotensin-(1-7) activates NADPH oxidase after ischemia-reperfusion in rat heart through AT1 receptor stimulation.Q45244185
Sodium status and angiotensin-converting enzyme inhibition: effects on plasma angiotensin-(1-7) in healthy man.Q45270252
Identification of angiotensin converting enzyme 2 in the rodent retina.Q46374769
G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptorQ46421423
Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive ratsQ46440284
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2.Q46493539
The renin angiotensin system in childhood hypertension: selective increase of angiotensin-(1-7) in essential hypertension.Q47236987
Angiotensin-converting enzyme 2 protects from severe acute lung failureQ47768368
Angiotensin-(1-7) immunoreactivity in the hypothalamus of the (mRen-2d)27 transgenic rat.Q47836966
Converting enzyme activity and angiotensin metabolism in the dog brainstem.Q48120667
In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive ratsQ48478548
State-of-the-Art lecture. Antiproliferative actions of angiotensin-(1-7) in vascular smooth muscleQ48581865
The renin-angiotensin system during acute myocardial ischemia in dogsQ49106527
Nomenclature for angiotensin receptors. A report of the Nomenclature Committee of the Council for High Blood Pressure Research.Q50701988
Contribution of angiotensin-(1-7) to blood pressure regulation in salt-depleted hypertensive rats.Q51380827
Gene expression analysis of ischemic and nonischemic cardiomyopathy: shared and distinct genes in the development of heart failure.Q51528582
No association of angiotensin-converting enzyme 2 gene (ACE2) polymorphisms with essential hypertension.Q51995128
Enhanced Renal Immunocytochemical Expression of ANG-(1-7) and ACE2 During PregnancyQ57185045
Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in humansQ57244745
Angiotensin-(1–7) Attenuates the Development of Heart Failure After Myocardial Infarction in RatsQ61965141
Potentiation of the hypotensive effect of bradykinin by angiotensin-(1–7)-related peptidesQ62124894
Angiotensins. A family that grows from withinQ68190280
The mosaic theory 32 years laterQ70310776
Differential regulation of prostaglandin synthesis by angiotensin peptides in porcine aortic smooth muscle cells: subtypes of angiotensin receptors involvedQ70724478
Angiotensins differentially activate phospholipase D in vascular smooth muscle cells from spontaneously hypertensive and Wistar-Kyoto ratsQ70882366
Angiotensin-(1-7) inhibits vascular smooth muscle cell growthQ71173612
Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertensionQ71503848
Angiotensin-(1-7) and nitric oxide interaction in renovascular hypertensionQ71688965
Antihypertensive actions of angiotensin-(1-7) in spontaneously hypertensive ratsQ71949723
Opposing actions of angiotensin-(1-7) and angiotensin II in the brain of transgenic hypertensive ratsQ72282326
Cardiovascular actions of angiotensin(1-7)Q72589225
Angiotensin-(1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxideQ73086568
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcirculatory systemQ11068
P304page(s)H2281-90
P577publication date2005-12-01
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titleAdvances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1-7) in regulation of cardiovascular function
P478volume289

Reverse relations

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