Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment

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Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment is …
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scholarly articleQ13442814

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P356DOI10.1177/0269881112444941
P3181OpenCitations bibliographic resource ID1616413
P698PubMed publication ID22526685
P5875ResearchGate publication ID224819603

P50authorNusrat HusainQ40160167
Bill DeakinQ43291499
Jaime Eduardo Cecilio HallakQ89090861
P2093author name stringSerdar Dursun
Paul Richardson
Graham Dunn
Fareed Minhas
Imran B Chaudhry
John Stirling
P2860cites workNMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication developmentQ28205016
A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophreniaQ28263942
N-acetyl cysteine as a glutathione precursor for schizophrenia--a double-blind, randomized, placebo-controlled trialQ28277707
Association of schizophrenia and autoimmune diseases: linkage of Danish national registersQ28300105
The positive and negative syndrome scale (PANSS) for schizophreniaQ28301751
Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia.Q33814201
A separate disease within the syndrome of schizophreniaQ34140437
Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison.Q34174069
Antipsychotic drug effects on brain morphology in first-episode psychosisQ34408860
Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine.Q34574117
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.Q34584573
Neurocognitive effectiveness of haloperidol, risperidone, and olanzapine in first-episode psychosis: a randomized, controlled 1-year follow-up comparisonQ34606845
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The NADPH oxidase NOX2 controls glutamate release: a novel mechanism involved in psychosis-like ketamine responsesQ42925757
Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial).Q43219125
Chronic administration of haloperidol and olanzapine attenuates ketamine-induced brain metabolic activationQ44355547
Minocycline as adjunctive therapy for schizophrenia: an open-label studyQ46330964
Frontal cortical and left temporal glutamatergic dysfunction in schizophreniaQ46659291
First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patientsQ46724711
Inhibition of thrombin-induced microglial activation and NADPH oxidase by minocycline protects dopaminergic neurons in the substantia nigra in vivoQ46747415
Focal gray matter changes in schizophrenia across the course of the illness: a 5-year follow-up studyQ48258798
Brain volume changes in the first year of illness and 5-year outcome of schizophrenia.Q48407980
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Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography study.Q53411974
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectschizophreniaQ41112
placeboQ269829
minocyclineQ415336
P304page(s)1185-93
P577publication date2012-09-01
P1433published inJournal of PsychopharmacologyQ6295819
P1476titleMinocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment
P478volume26