Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia.

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Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia. is …
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scholarly articleQ13442814

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P356DOI10.1001/ARCHGENPSYCHIATRY.2010.199
P932PMC publication ID3476840
P698PubMed publication ID21300943
P5875ResearchGate publication ID49817143

P50authorNancy Coover AndreasenQ4065393
Vincent A. MagnottaQ26932611
Beng-Choon HoQ56246054
P2093author name stringRonald Pierson
Steven Ziebell
P2860cites workEffect of chronic antipsychotic exposure on astrocyte and oligodendrocyte numbers in macaque monkeysQ24654374
Reduced dendritic spine density in auditory cortex of subjects with schizophreniaQ24658134
Effect of antipsychotics on regional cerebral blood flow measured with positron emission tomographyQ48609948
Brain volume changes in schizophrenia: how do they arise? What do they mean?Q48653346
Schizophrenia as a chronic active brain process: a study of progressive brain structural change subsequent to the onset of schizophreniaQ48660056
Childhood-onset schizophrenia: brain MRI rescan after 2 years of clozapine maintenance treatmentQ49048938
Insular cortex abnormalities in schizophrenia: Relationship to symptoms and typical neuroleptic exposureQ49061545
National trends in the outpatient treatment of children and adolescents with antipsychotic drugs.Q51801492
Effects of atypical and typical neuroleptics on anterior cingulate volume in schizophrenia.Q51925921
Morphometry of the superior temporal plane in schizophrenia: relationship to clinical correlates.Q51937304
The Comprehensive Assessment of Symptoms and History (CASH). An instrument for assessing diagnosis and psychopathology.Q52042140
The global assessment scale. A procedure for measuring overall severity of psychiatric disturbanceQ52112284
Psychosis and brain volume changes during the first five years of schizophreniaQ60610021
The Iowa prospective longitudinal study of recent-onset psychosesQ67563066
Dose equivalence of the antipsychotic drugsQ70058149
Caudate nuclei volumes in schizophrenic patients treated with typical antipsychotics or clozapineQ72540541
Total nerve cell number in neocortex in chronic schizophrenics and controls estimated using optical disectorsQ72734923
Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophreniaQ30994462
The effects of antipsychotic treatment on cerebral structure and function in schizophreniaQ31120604
What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophreniaQ31147040
Antipsychotic treatment induces alterations in dendrite- and spine-associated proteins in dopamine-rich areas of the primate cerebral cortexQ31864319
Progressive brain volume changes and the clinical course of schizophrenia in men: a longitudinal magnetic resonance imaging studyQ33181630
Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findingsQ33425487
Results of a longitudinal analysis of national data to examine relationships between organizational and market characteristics and changes in antipsychotic prescribing in US nursing homes from 1996 through 2006.Q33483929
The effects of antipsychotics on the brain: what have we learnt from structural imaging of schizophrenia?--a systematic review.Q33494667
Progressive decrease of left superior temporal gyrus gray matter volume in patients with first-episode schizophreniaQ33754399
Progressive decrease of left Heschl gyrus and planum temporale gray matter volume in first-episode schizophrenia: a longitudinal magnetic resonance imaging studyQ33983993
The influence of chronic exposure to antipsychotic medications on brain size before and after tissue fixation: a comparison of haloperidol and olanzapine in macaque monkeysQ33985626
Mapping cortical change across the human life spanQ34172914
Antipsychotic drug effects on brain morphology in first-episode psychosisQ34408860
Subcortical MRI volumes in neuroleptic-naive and treated patients with schizophreniaQ34482389
Effect of chronic exposure to antipsychotic medication on cell numbers in the parietal cortex of macaque monkeysQ34576434
Association between brain-derived neurotrophic factor Val66Met gene polymorphism and progressive brain volume changes in schizophreniaQ34706991
Validity of symptom assessment in psychotic disorders: information variance across different sources of historyQ35751934
Progressive brain change in schizophrenia: a prospective longitudinal study of first-episode schizophreniaQ36395044
Antipsychotic dose equivalents and dose-years: a standardized method for comparing exposure to different drugs.Q36914354
Who are the new users of antipsychotic medications?Q37337653
Neuroleptic withdrawal in schizophrenic patients. A review of the literatureQ40602444
Longitudinal study of brain morphology in first episode schizophreniaQ40718665
Magnetic resonance imaging abnormalities in lenticular nuclei and cerebral cortex in schizophreniaQ41168210
Comparison of the effects of risperidone and haloperidol on regional cerebral blood flow in schizophreniaQ43582604
The effects of neuroleptic medications on basal ganglia blood flow in schizophreniform disorders: a comparison between the neuroleptic-naïve and medicated statesQ44193616
Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17.Q45307345
Dysregulated brain development in adult men with schizophrenia: a magnetic resonance imaging studyQ46273440
Change in basal ganglia volume over 2 years in patients with schizophrenia: typical versus atypical neurolepticsQ48134165
Neurotoxicity, neuroplasticity, and magnetic resonance imaging morphometryQ48229217
Focal gray matter changes in schizophrenia across the course of the illness: a 5-year follow-up studyQ48258798
Progressive structural brain abnormalities and their relationship to clinical outcome: a longitudinal magnetic resonance imaging study early in schizophrenia.Q48286419
Brain volume changes in first-episode schizophrenia: a 1-year follow-up studyQ48452819
Decreased caudate volume in neuroleptic-naive psychotic patientsQ48454154
A follow-up magnetic resonance imaging study of schizophrenia. Relationship of neuroanatomical changes to clinical and neurobehavioral measuresQ48519543
Subcortical and temporal structures in affective disorder and schizophrenia: a magnetic resonance imaging studyQ48539180
The effects of antipsychotics on brain structure: what have we learnt from structural imaging of schizophrenia?Q48596750
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectschizophreniaQ41112
P304page(s)128-137
P577publication date2011-02-01
P1433published inJAMA PsychiatryQ635830
P1476titleLong-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia
P478volume68

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cites work (P2860)
Q48496797'Prodromal' diagnosis of psychosis: Ethical problems in research and clinical practice
Q40706433A History of Psychosis in Bipolar Disorder is Associated With Gray Matter Volume Reduction
Q58106866A Place for Subjectivity in Psychiatry
Q89544041A Prospective Longitudinal Investigation of Cortical Thickness and Gyrification in Schizophrenia
Q36600804A Review of Brain-derived Neurotrophic Factor as a Candidate Biomarker in Schizophrenia
Q47635161A brain-wide association study of DISC1 genetic variants reveals a relationship with the structure and functional connectivity of the precuneus in schizophrenia.
Q36049650A framework for interpreting functional networks in schizophrenia
Q28539784A longitudinal study of alterations of hippocampal volumes and serum BDNF levels in association to atypical antipsychotics in a sample of first-episode patients with schizophrenia
Q48681125A longitudinal study of cortical changes and their cognitive correlates in patients followed up after first-episode psychosis
Q36692829A multimodal analysis of antipsychotic effects on brain structure and function in first-episode schizophrenia.
Q38629163A neurodevelopment and neuroplasticity-based framework for early intervention in psychotic disorders.
Q21558428A review of structural neuroimaging in schizophrenia: from connectivity to connectomics
Q24288871A systematic examination of brain volumetric abnormalities in recent-onset schizophrenia using voxel-based, surface-based and region-of-interest-based morphometric analyses
Q38194900A systematic review of antipsychotic drug effects on human gene expression related to risk factors for cardiovascular disease
Q91048454A transdiagnostic neuroanatomical signature of psychiatric illness
Q89091254A within-subject consideration of the psychotic spectrum disorder concept in a patient in remission associated with cortical gray matter recovery
Q44277658Aberrations in the arcuate fasciculus are associated with auditory verbal hallucinations in psychotic and in non-psychotic individuals
Q35783530Abnormalities in structural covariance of cortical gyrification in schizophrenia
Q26741515Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment
Q36579982Age at First Episode Modulates Diagnosis-Related Structural Brain Abnormalities in Psychosis
Q40994321Age-related cortical thickness trajectories in first episode psychosis patients presenting with early persistent negative symptoms.
Q42278927Age-related increase in the number of oligodendrocytes is dysregulated in schizophrenia and mood disorders
Q47882769Alcohol use is associated with thinner cerebral cortex and larger ventricles in schizophrenia, bipolar disorder and healthy controls
Q31155367Alteration of gray matter microstructure in schizophrenia
Q36817204Altered Thalamo-Cortical White Matter Connectivity: Probabilistic Tractography Study in Clinical-High Risk for Psychosis and First-Episode Psychosis
Q34700949Altered cortical thickness related to clinical severity but not the untreated disease duration in schizophrenia.
Q39133107An Auto-Ethnographic Study of "Open Dialogue": The Illumination of Snow
Q48007135An investigation of regional cerebral blood flow and tissue structure changes after acute administration of antipsychotics in healthy male volunteers
Q34589580Anatomical abnormalities in gray and white matter of the cortical surface in persons with schizophrenia
Q57519639Antidepressant, antipsychotic and psychological interventions in subjects at high clinical risk for psychosis: OASIS 6-year naturalistic study
Q45290173Antidopaminergic Medication is Associated with More Rapidly Progressive Huntington's Disease
Q50759017Antipsychotic drugs for prevention of relapse.
Q38084211Antipsychotic interventions in prodromal psychosis: safety issues
Q36915452Antipsychotic pharmacogenomics in first episode psychosis: a role for glutamate genes
Q33777656Antipsychotics activate mTORC1-dependent translation to enhance neuronal morphological complexity
Q53092564Antipsychotics decrease response confidence.
Q57825253Are structural brain changes in schizophrenia related to antipsychotic medication? A narrative review of the evidence from a clinical perspective
Q41687584Aripiprazole and Riluzole treatment alters behavior and neurometabolites in young ADHD rats: a longitudinal 1H-NMR spectroscopy study at 11.7T
Q47741746Association between using medications with anticholinergic properties and short-term cognitive decline among older men: A retrospective cohort study in Taiwan
Q57039080Association of Age at Onset and Longitudinal Course of Prefrontal Function in Youth With Schizophrenia
Q92667458Association of antidepressants with brain morphology in early stages of psychosis: an imaging genomics approach
Q52152130Association of serum VEGF levels with prefrontal cortex volume in schizophrenia.
Q52600030Associations between adolescent cannabis use and brain structure in psychosis.
Q47583502Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains.
Q37956422Atypical mood stabilizers: a new role for neuroleptics?
Q35852767Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine.
Q90176158BDNF Serum Levels are Associated With White Matter Microstructure in Schizophrenia - A Pilot Study
Q33566832BDNF Val66Met polymorphism and antipsychotic-induced tardive dyskinesia occurrence and severity: a meta-analysis
Q97521512Barriers to stopping neuroleptic (antipsychotic) treatment in people with schizophrenia, psychosis or bipolar disorder
Q70851694Benefits and harms of antipsychotic drugs in drug-naïve patients with psychosis: A systematic review
Q37971465Beyond the facts in schizophrenia: closing the gaps in diagnosis, pathophysiology, and treatment.
Q34447051Biomarkers and clinical staging in psychiatry
Q37124940Brain Biomarkers of Vulnerability and Progression to Psychosis
Q26786247Brain Functional Effects of Psychopharmacological Treatments in Schizophrenia: A Network-based Functional Perspective Beyond Neurotransmitter Systems
Q26786253Brain Structural Effects of Antipsychotic Treatment in Schizophrenia: A Systematic Review
Q26786245Brain Structural Effects of Psychopharmacological Treatment in Bipolar Disorder
Q47386048Brain Structure Biomarkers in the Psychosis Biotypes: Findings From the Bipolar-Schizophrenia Network for Intermediate Phenotypes
Q36148488Brain Structure in Neuropsychologically Defined Subgroups of Schizophrenia and Psychotic Bipolar Disorder
Q50419808Brain Subtyping Enhances The Neuroanatomical Discrimination of Schizophrenia.
Q48118494Brain TSPO imaging and gray matter volume in schizophrenia patients and in people at ultra high risk of psychosis: An [(11)C]PBR28 study
Q36660287Brain gray matter phenotypes across the psychosis dimension
Q33948574Brain tissue changes and antipsychotic medication
Q47859361Brain volume change in first-episode psychosis: an effect of antipsychotic medication independent of BMI change
Q48243224Brain volume changes over the first year of treatment in schizophrenia: relationships to antipsychotic treatment
Q38762872Brain-imaging studies of treatment-resistant schizophrenia: a systematic review
Q45071432Can long-term treatment with antipsychotic drugs lead to structural brain damage? Against
Q34899462Cannabinoid receptor 1 gene polymorphisms and marijuana misuse interactions on white matter and cognitive deficits in schizophrenia.
Q30558464Cannabis abuse and brain morphology in schizophrenia: a review of the available evidence
Q33699076Cavum septum pellucidum and first-episode psychosis: A meta-analysis.
Q34556900Cerebellar Morphology and Procedural Learning Impairment in Neuroleptic-Naive Youth at Ultrahigh Risk of Psychosis
Q34021040Challenges associated with application of clinical staging models to psychotic disorders
Q48608193Chances and problems of the recovery approach from a psychiatric viewpoint
Q94600188Characteristics of gray matter alterations in never-treated and treated chronic schizophrenia patients
Q48358415Characterization of white matter abnormalities in early-stage schizophrenia
Q37412453Chronic exposure to haloperidol and olanzapine leads to common and divergent shape changes in the rat hippocampus in the absence of grey-matter volume loss
Q55437545Classification of multi-site MR images in the presence of heterogeneity using multi-task learning☆.
Q35109168Clinical predictors of therapeutic response to antipsychotics in schizophrenia
Q38163315Clinical problems encountered in the treatment of adolescents with anorexia nervosa
Q38026886Clozapine for the treatment of schizophrenia
Q22251382Cognitive behavioural therapy for psychosis prevention: a systematic review and meta-analysis
Q95386203Cognitive therapy for people with a schizophrenia spectrum diagnosis not taking antipsychotic medication: an exploratory trial
Q50660859Cognitive therapy for people with schizophrenia spectrum disorders not taking antipsychotic drugs: a single-blind randomised controlled trial.
Q39566093Connectivity of the anterior insula differentiates participants with first-episode schizophrenia spectrum disorders from controls: a machine-learning study.
Q39070362Connectomic correlates of response to treatment in first-episode psychosis.
Q54965265Corpus callosum volumes in the 5 years following the first-episode of schizophrenia: Effects of antipsychotics, chronicity and maturation.
Q34274338Correlating anterior insula gray matter volume changes in young people with clinical and neurocognitive outcomes: an MRI study
Q34701018Correlations between brain structure and symptom dimensions of psychosis in schizophrenia, schizoaffective, and psychotic bipolar I disorders
Q55983721Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium
Q39066784Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group
Q37622623Cortical grey matter volume reduction in people with schizophrenia is associated with neuro-inflammation
Q30368997Cortical network dysfunction caused by a subtle defect of myelination.
Q35818882Cortical structural abnormalities in deficit versus nondeficit schizophrenia
Q88593547Cortical structures and their clinical correlates in antipsychotic-naïve schizophrenia patients before and after 6 weeks of dopamine D2/3 receptor antagonist treatment
Q44225154Cortical thickness in individuals with non-clinical and clinical psychotic symptoms
Q33826006Cortical thinning in temporo-parietal junction (TPJ) in non-affective first-episode of psychosis patients with persistent negative symptoms
Q39459514Critical analysis on the present methods for brain volume measurements in multiple sclerosis
Q36096550Design and protocol for the Focusing on Clozapine Unresponsive Symptoms (FOCUS) trial: a randomised controlled trial.
Q41560807Detecting neuroimaging biomarkers for schizophrenia: a meta-analysis of multivariate pattern recognition studies
Q30459202Dexamphetamine selectively increases 40 Hz auditory steady state response power to target and nontarget stimuli in healthy humans
Q36167245Diagnostic neuroimaging across diseases
Q87992766Diffusion Imaging of White Matter In Schizophrenia: Progress and Future Directions
Q30592331Diffusion tensor imaging findings of white matter changes in first episode schizophrenia: a systematic review
Q48594731Dissociable morphometric differences of the inferior parietal lobule in schizophrenia
Q37131018Distinguishing prodromal from first-episode psychosis using neuroanatomical single-subject pattern recognition
Q35550905Divergent effects of first-generation and second-generation antipsychotics on cortical thickness in first-episode psychosis
Q34254903Do all schizophrenia patients need antipsychotic treatment continuously throughout their lifetime? A 20-year longitudinal study
Q38060256Do subjects at clinical high risk for psychosis differ from those with a genetic high risk?--A systematic review of structural and functional brain abnormalities.
Q39680515Do they see dead people? Cultural factors and sensitivity in screening for schizophrenia spectrum disorders
Q50703532Does body shaping influence brain shape? Habitual physical activity is linked to brain morphology independent of age.
Q52652401Does treatment of schizophrenia with antipsychotic medications eliminate or reduce psychosis? A 20-year multi-follow-up study.
Q36148481Dose Equivalents for Second-Generation Antipsychotic Drugs: The Classical Mean Dose Method
Q89022593Dynamic Reorganization of Functional Connectivity Reveals Abnormal Temporal Efficiency in Schizophrenia
Q48016096Dynamic cerebral reorganization in the pathophysiology of schizophrenia: a MRI-derived cortical thickness study.
Q91067874Dynamic changes of functional segregation and integration in vulnerability and resilience to schizophrenia
Q35873850Early detection and intervention evaluation for people at risk of psychosis: multisite randomised controlled trial.
Q89891607Effects of Antipsychotic Medication on Brain Structure in Patients With Major Depressive Disorder and Psychotic Features: Neuroimaging Findings in the Context of a Randomized Placebo-Controlled Clinical Trial
Q34747371Effects of age on white matter integrity and negative symptoms in schizophrenia
Q48026458Effects of childhood trauma on left inferior frontal gyrus function during response inhibition across psychotic disorders
Q34068878Elevated concentrations of neurofilament light chain in the cerebrospinal fluid of bipolar disorder patients
Q57892499Engaging People with Psychosis in Acceptance and Commitment Therapy and Mindfulness
Q38988333Episodic memory functions in first episode psychosis and clinical high risk individuals
Q37975281Ethical implications for clinical practice and future research in "at risk" individuals.
Q57810372Ethics of giving antipsychotic medication to at-risk young people
Q38613680Experiences of antipsychotic use in patients with early psychosis: a two-year follow-up study
Q37623597Explaining attitudes and adherence to antipsychotic medication: the development of a process model
Q50664683Extensive brain structural network abnormality in first-episode treatment-naive patients with schizophrenia: morphometrical and covariation study.
Q35965893Extensive gray matter volume reduction in treatment-resistant schizophrenia.
Q39248594Extrastriatal dopamine D2/3 receptors and cortical grey matter volumes in antipsychotic-naïve schizophrenia patients before and after initial antipsychotic treatment
Q37730408Familial and environmental influences on brain volumes in twins with schizophrenia
Q50761921First, do no harm: confronting the myths of psychiatric drugs.
Q50556051First- and second-generation antipsychotic drug treatment and subcortical brain morphology in schizophrenia.
Q38893848Forty years of structural imaging in psychosis: promises and truth
Q36609798Frontal fasciculi and psychotic symptoms in antipsychotic-naive patients with schizophrenia before and after 6 weeks of selective dopamine D2/3 receptor blockade
Q48453000Frontal lobe function and social adjustment in patients with schizophrenia: near-infrared spectroscopy
Q92518217Functional brain networks in never-treated and treated long-term Ill schizophrenia patients
Q37602607Future in psychopathology research
Q48254506GLP-1 receptor agonist liraglutide reverses long-term atypical antipsychotic treatment associated behavioral depression and metabolic abnormalities in rats
Q45988102Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms.
Q37196005Genome-wide association analysis with gray matter volume as a quantitative phenotype in first-episode treatment-naïve patients with schizophrenia
Q47668735Gray matter changes and cognitive predictors of 2-year follow-up abnormalities in early-onset first-episode psychosis
Q48895267Gray matter volume as an intermediate phenotype for psychosis: Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP).
Q24606392Gray matter volume in schizophrenia and bipolar disorder with psychotic features
Q36960391Heritability of multivariate gray matter measures in schizophrenia
Q36377853Hippocampal Shape Abnormalities Predict Symptom Progression in Neuroleptic-Free Youth at Ultrahigh Risk for Psychosis
Q49616477Hippocampal Subregions Across the Psychosis Spectrum
Q36390750Hippocampal shape and volume changes with antipsychotics in early stage psychotic illness
Q34700980Hippocampal volume is reduced in schizophrenia and schizoaffective disorder but not in psychotic bipolar I disorder demonstrated by both manual tracing and automated parcellation (FreeSurfer).
Q31054567History of the Concept of Disconnectivity in Schizophrenia
Q28087255How Schizophrenia Develops: Cognitive and Brain Mechanisms Underlying Onset of Psychosis
Q35610726How can neuroimaging facilitate the diagnosis and stratification of patients with psychosis?
Q86708206How effective are the current treatments for children diagnosed with manic/mixed bipolar disorder?
Q49083694Hypothalamus and pituitary volume in schizophrenia: a structural MRI study
Q23890289Identification of a common neurobiological substrate for mental illness
Q36304801Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential
Q47871481Immediate-Early Genes Modulation by Antipsychotics: Translational Implications for a Putative Gateway to Drug-Induced Long-Term Brain Changes.
Q41084707Impact of polygenic schizophrenia-related risk and hippocampal volumes on the onset of psychosis
Q38955513Improving Current Treatments for Schizophrenia
Q42358625In search of an evidence-based role for psychiatry
Q92950030Individual Alpha Peak Frequency Moderates Transfer of Learning in Cognitive Remediation of Schizophrenia
Q36066670Individualized differential diagnosis of schizophrenia and mood disorders using neuroanatomical biomarkers
Q93069431Inefficient neural system stabilization: a theory of spontaneous resolutions and recurrent relapses in psychosis
Q36828285Influence of Antipsychotic and Anticholinergic Loads on Cognitive Functions in Patients with Schizophrenia
Q89572022Influence of More Than 5 Years of Continuous Exposure to Antipsychotics on Cerebral Functional Connectivity of Chronic Schizophrenia
Q37367250Influence of ZNF804a on brain structure volumes and symptom severity in individuals with schizophrenia.
Q36145094Insular volume abnormalities associated with different transition probabilities to psychosis
Q35878916Intact relational memory and normal hippocampal structure in the early stage of psychosis
Q91320613Integrating machining learning and multimodal neuroimaging to detect schizophrenia at the level of the individual
Q38376655Is duration of illness really influencing outcome in major psychoses?
Q36260919Joint Coupling of Awake EEG Frequency Activity and MRI Gray Matter Volumes in the Psychosis Dimension: A BSNIP Study
Q48364325Key functional circuitry altered in schizophrenia involves parietal regions associated with sense of self
Q36148454Lack of Evidence for Regional Brain Volume or Cortical Thickness Abnormalities in Youths at Clinical High Risk for Psychosis: Findings From the Longitudinal Youth at Risk Study
Q89088687Linked 4-Way Multimodal Brain Differences in Schizophrenia in a Large Chinese Han Population
Q33655392Local gyrification index in probands with psychotic disorders and their first-degree relatives
Q33853511Long term antipsychotic treatment does not alter metabolite concentrations in rat striatum: an in vivo magnetic resonance spectroscopy study.
Q34681347Long-term antipsychotic use and brain changes in schizophrenia - a systematic review and meta-analysis
Q70846418Long-term harms from previous use of selective serotonin reuptake inhibitors: A systematic review
Q35217858Longer lithium exposure is associated with better white matter integrity in older adults with bipolar disorder
Q33921159Longitudinal changes in total brain volume in schizophrenia: relation to symptom severity, cognition and antipsychotic medication
Q48466370Longitudinal follow-up of cavum septum pellucidum and adhesio interthalamica alterations in first-episode psychosis: a population-based MRI study
Q36157849Longitudinal regional brain volume loss in schizophrenia: Relationship to antipsychotic medication and change in social function
Q46147870Longitudinal study of cerebral surface morphology in youth with 22q11.2 deletion syndrome, and association with positive symptoms of psychosis
Q37358080MAPK14 and CNR1 gene variant interactions: effects on brain volume deficits in schizophrenia patients with marijuana misuse
Q55508141Maintenance antipsychotic treatment versus discontinuation strategies following remission from first episode psychosis: systematic review.
Q92932105Mechanisms and therapeutic significance of autophagy modulation by antipsychotic drugs
Q33762467Meta-analysis of cognitive deficits in ultra-high risk to psychosis and first-episode psychosis: do the cognitive deficits progress over, or after, the onset of psychosis?
Q35909333Metacognition-augmented cognitive remediation training reduces jumping to conclusions and overconfidence but not neurocognitive deficits in psychosis
Q92245093Micro- and Macrostructural White Matter Integrity in Never-Treated and Currently Unmedicated Patients With Schizophrenia and Effects of Short-Term Antipsychotic Treatment
Q28265163Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment
Q47841028Modular-level alterations of structure-function coupling in schizophrenia connectome.
Q37262794Morphological Alterations in the Thalamus, Striatum, and Pallidum in Autism Spectrum Disorder.
Q92417080Morphological Profiling of Schizophrenia: Cluster Analysis of MRI-Based Cortical Thickness Data
Q89959086Motor abnormalities and basal ganglia in first-episode psychosis (FEP)
Q50420417Multivariate Associations Among Behavioral, Clinical, and Multimodal Imaging Phenotypes in Patients With Psychosis.
Q50573955NEURAPRO-E study protocol: a multicentre randomized controlled trial of omega-3 fatty acids and cognitive-behavioural case management for patients at ultra high risk of schizophrenia and other psychotic disorders.
Q64085430Nerve Growth Factor Serum Levels Are Associated With Regional Gray Matter Volume Differences in Schizophrenia Patients
Q89320261Neural correlates of global and specific cognitive deficits in schizophrenia
Q38310750Neural oscillations as a translational tool in schizophrenia research: rationale, paradigms and challenges
Q41920722Neuroanatomical classification in a population-based sample of psychotic major depression and bipolar I disorder with 1 year of diagnostic stability
Q36386404Neuroanatomical maps of psychosis onset: voxel-wise meta-analysis of antipsychotic-naive VBM studies
Q46146851Neuroanatomical markers of genetic liability to psychosis and first episode psychosis: a voxelwise meta-analytical comparison
Q38026435Neurobiological correlates of delusion: beyond the salience attribution hypothesis
Q38175169Neurobiological effects of physical exercise in schizophrenia: a systematic review
Q37981491Neuroglialpharmacology: myelination as a shared mechanism of action of psychotropic treatments
Q36378169Neuroimaging predictors of functional outcomes in schizophrenia at baseline and 6-month follow-up
Q47382752Neuroprogression and episode recurrence in bipolar I disorder: A study of gray matter volume changes in first-episode mania and association with clinical outcome
Q35505540Neuropsychology, autobiographical memory, and hippocampal volume in "younger" and "older" patients with chronic schizophrenia
Q30582343Neuropsychopharmacology of auditory hallucinations: insights from pharmacological functional MRI and perspectives for future research
Q50556987No progressive brain changes during a 1-year follow-up of patients with first-episode psychosis.
Q42347518On discontinuing treatment in schizophrenia: a clinical conundrum
Q47322741Optical coherence tomography indices of structural retinal pathology in schizophrenia
Q38086645Optimizing outcomes in schizophrenia: long-acting depots and long-term treatment
Q35999354Patients with Schizophrenia Fail to Up-Regulate Task-Positive and Down-Regulate Task-Negative Brain Networks: An fMRI Study Using an ICA Analysis Approach
Q34041815Patients with poor response to antipsychotics have a more severe pattern of frontal atrophy: a voxel-based morphometry study of treatment resistance in schizophrenia
Q39646600Patterns of regional gray matter loss at different stages of schizophrenia: A multisite, cross-sectional VBM study in first-episode and chronic illness
Q58276450Perphenazine and trifluoperazine induce mitochondria-mediated cell death in SH-SY5Y cells
Q50527605Personal Accounts of Discontinuing Neuroleptic Medication for Psychosis.
Q34807152Pharmacogenetic associations of the type-3 metabotropic glutamate receptor (GRM3) gene with working memory and clinical symptom response to antipsychotics in first-episode schizophrenia
Q34274859Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents
Q92080750Positive and Negative Effects of Antipsychotic Medication: An International Online Survey of 832 Recipients
Q31095968Predicting individualized clinical measures by a generalized prediction framework and multimodal fusion of MRI data
Q44658919Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium.
Q30529640Prefrontal gray matter morphology mediates the association between serum anticholinergicity and cognitive functioning in early course schizophrenia
Q64113447Prognostic Utility of Multivariate Morphometry in Schizophrenia
Q35960362Progressive Brain Atrophy and Cortical Thinning in Schizophrenia after Commencing Clozapine Treatment
Q36395044Progressive brain change in schizophrenia: a prospective longitudinal study of first-episode schizophrenia
Q34351095Progressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies.
Q24626182Progressive loss of cortical gray matter in schizophrenia: a meta-analysis and meta-regression of longitudinal MRI studies
Q34691699Progressive reduction in cortical thickness as psychosis develops: a multisite longitudinal neuroimaging study of youth at elevated clinical risk
Q91731927Progressive subcortical volume loss in treatment-resistant schizophrenia patients after commencing clozapine treatment
Q58122155Propionate Protects Haloperidol-Induced Neurite Lesions Mediated by Neuropeptide Y
Q38399332Proteome and pathway effects of chronic haloperidol treatment in mouse hippocampus.
Q38984616Psychiatrist's adherence: a new factor in relapse prevention of schizophrenia. A randomized controlled study on relapse control through telemedicine system
Q31137558Psychoradiology: The Frontier of Neuroimaging in Psychiatry.
Q34467748Qualitative investigation of targets for and barriers to interventions to prevent psychosis relapse
Q38911287Quantifying the Interaction and Contribution of Multiple Datasets in Fusion: Application to the Detection of Schizophrenia
Q42374185Real-world effectiveness of antipsychotics
Q34337272Relapse duration, treatment intensity, and brain tissue loss in schizophrenia: a prospective longitudinal MRI study.
Q48189224Relationships between corpus callosum and language lateralization in patients with schizophrenia and bipolar disorders
Q46567488Response to Targeted Cognitive Training Correlates with Change in Thalamic Volume in a Randomized Trial for Early Schizophrenia
Q37451498Resting-state fMRI connectivity impairment in schizophrenia and bipolar disorder
Q59129268Resting-state gamma-band power alterations in schizophrenia reveal E/I-balance abnormalities across illness-stages
Q26776255Rethinking psychopharmacotherapy: The role of treatment context and brain plasticity in antidepressant and antipsychotic interventions
Q57312955Risk of dementia associated with psychotic disorders in later life: the health in men study (HIMS)
Q92282698Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration
Q56959104Schizophrenia
Q104134881Schizophrenia polygenic risk predicts general cognitive deficit but not cognitive decline in healthy older adults
Q47677836Schizophrenia: Basic and Clinical
Q34023115Schizophrenia: an integrated sociodevelopmental-cognitive model
Q47834944Shared and distinct alterations of white matter tracts in remitted and nonremitted patients with schizophrenia.
Q42362623Short-term mechanisms influencing volumetric brain dynamics
Q34635905Should attenuated psychosis syndrome be included in DSM-5?
Q47301729State-dependent microstructural white matter changes in drug-naïve patients with first-episode psychosis.
Q34250017Striatal presynaptic dopamine in schizophrenia, part II: meta-analysis of [(18)F/(11)C]-DOPA PET studies
Q39271880Striatal shape abnormalities as novel neurodevelopmental endophenotypes in schizophrenia: a longitudinal study.
Q36117393Structural abnormalities in the cuneus associated with Herpes Simplex Virus (type 1) infection in people at ultra high risk of developing psychosis
Q59135280Structural and functional brain abnormalities in drug-naive, first-episode, and chronic patients with schizophrenia: a multimodal MRI study
Q34341124Structural and functional neuroimaging studies in major depressive disorder with psychotic features: a critical review
Q37131057Structural brain alterations associated with schizophrenia preceded by conduct disorder: a common and distinct subtype of schizophrenia?
Q34393431Structural brain changes associated with antipsychotic treatment in schizophrenia as revealed by voxel-based morphometric MRI: an activation likelihood estimation meta-analysis
Q36348922Structural brain changes in schizophrenia at different stages of the illness: A selective review of longitudinal magnetic resonance imaging studies
Q30668157Structural correlates of formal thought disorder in schizophrenia: An ultra-high field multivariate morphometry study
Q88577624Structural covariance and cortical reorganisation in schizophrenia: a MRI-based morphometric study
Q38812229Structural neuroimaging across early-stage psychosis: Aberrations in neurobiological trajectories and implications for the staging model.
Q23747506Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
Q36395488Successful management of clozapine adverse effects with extended (alternate day) antipsychotic dosing in a patient with schizophrenia
Q37202142Supervised, Multivariate, Whole-Brain Reduction Did Not Help to Achieve High Classification Performance in Schizophrenia Research
Q48901567Surface-based brain morphometry and diffusion tensor imaging in schizoaffective disorder
Q34564212Sustaining remission of psychotic depression: rationale, design and methodology of STOP-PD II
Q48481845Swertisin ameliorates pre-pulse inhibition deficits and cognitive impairment induced by MK-801 in mice
Q50205158Symptoms, functioning and coping strategies in individuals with schizophrenia spectrum disorders who do not take antipsychotic medication: a comparative interview study.
Q41156644Targeted intermittent treatment in chronic schizophrenia
Q28077138The Longitudinal Course of Schizophrenia Across the Lifespan: Clinical, Cognitive, and Neurobiological Aspects
Q38570636The Use of Continuous Treatment Versus Placebo or Intermittent Treatment Strategies in Stabilized Patients with Schizophrenia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with First- and Second-Generation Antipsychotics
Q34649187The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: update 2012 on the long-term treatment of bipolar disorder
Q36591384The association of white matter volume in psychotic disorders with genotypic variation in NRG1, MOG and CNP: a voxel-based analysis in affected individuals and their unaffected relatives
Q90728397The debate regarding maintenance treatment with antipsychotic drugs in schizophrenia
Q44668111The effect of aerobic exercise on cortical architecture in patients with chronic schizophrenia: a randomized controlled MRI study.
Q47155737The effect of duration of illness and antipsychotics on subcortical volumes in schizophrenia: Analysis of 778 subjects
Q43032610The field of schizophrenia: strengths, weaknesses, opportunities, and threats
Q97556098The mGluR2/3 agonist pomaglumetad methionil normalizes aberrant dopamine neuron activity via action in the ventral hippocampus
Q64950972The meaning of group differences in cognitive test performance.
Q48318194The medicalisation of "ups and downs": the marketing of the new bipolar disorder
Q24067152The myth of schizophrenia as a progressive brain disease
Q38232366The neurobiology and treatment of first-episode schizophrenia
Q46558915The oft-times overlooked "pharmacologic" relapse in schizophrenia
Q96302720The polygenic architecture of schizophrenia - rethinking pathogenesis and nosology
Q38061036The psychosis high-risk state: a comprehensive state-of-the-art review
Q96773916The report of the joint WPA/CINP workgroup on the use and usefulness of antipsychotic medication in the treatment of schizophrenia
Q34418847The role of long-acting injectable antipsychotics in schizophrenia: a critical appraisal.
Q48746770The visual cortex in schizophrenia: alterations of gyrification rather than cortical thickness--a combined cortical shape analysis
Q30575242Three-way (N-way) fusion of brain imaging data based on mCCA+jICA and its application to discriminating schizophrenia
Q45775101Three-year longitudinal population-based volumetric MRI study in first-episode schizophrenia spectrum patients.
Q37230904Time-dependent effects of haloperidol on glutamine and GABA homeostasis and astrocyte activity in the rat brain
Q26860217Translating the MAM model of psychosis to humans
Q48231299Treatment of delirium with risperidone in cancer patients
Q35673737Twenty Years of Schizophrenia Research in the Northern Finland Birth Cohort 1966: A Systematic Review
Q64231585Twenty years of misdiagnosis of schizophrenia in a patient with Dandy-Walker variant syndrome
Q89901286Two distinct neuroanatomical subtypes of schizophrenia revealed using machine learning
Q37896626Understanding aberrant white matter development in schizophrenia: an avenue for therapy?
Q48628524Use of antipsychotic medication and suicidality--the Northern Finland Birth Cohort 1966.
Q30686416Use of proton magnetic resonance spectroscopy in the treatment of psychiatric disorders: a critical update
Q89669017Using Open Questions to Understand 650 People's Experiences With Antipsychotic Drugs
Q60460701Using the cognitive assessment interview to screen cognitive impairment in psychosis
Q38697215Ventricular volumes across stages of schizophrenia and other psychoses
Q38473103Verbal learning and memory and their associations with brain morphology and illness course in schizophrenia spectrum psychoses
Q48038781Views of early psychosis clinicians on discontinuation of antipsychotic medication following symptom remission in first episode psychosis
Q43762923Volume increases in putamen associated with positive symptom reduction in previously drug-naive schizophrenia after 6 weeks antipsychotic treatment.
Q34034400Volumetric changes in the basal ganglia after antipsychotic monotherapy: a systematic review
Q33935798Voxel-based gray and white matter morphometry correlates of hallucinations in schizophrenia: The superior temporal gyrus does not stand alone
Q48569172What determines continuing grey matter changes in first-episode schizophrenia and affective psychosis?
Q55023835What is the risk-benefit ratio of long-term antipsychotic treatment in people with schizophrenia?
Q37272654White matter alterations in antipsychotic- and mood stabilizer-naïve individuals with bipolar II/NOS disorder
Q34406905White matter alterations in bipolar disorder: potential for drug discovery and development
Q37705723White matter changes associated with antipsychotic treatment in first-episode psychosis
Q27686764White matter development in the early stages of psychosis.
Q37477310White matter integrity as a predictor of response to treatment in first episode psychosis
Q34778177White matter microstructural abnormalities of the cingulum bundle in youths with 22q11.2 deletion syndrome: associations with medication, neuropsychological function, and prodromal symptoms of psychosis
Q40119382White-matter connectivity related to paliperidone treatment response in patients with schizophrenia
Q48148097White-matter microstructure in previously drug-naive patients with schizophrenia after 6 weeks of treatment
Q48204422ZNF804A rs1344706 is associated with cortical thickness, surface area, and cortical volume of the unmedicated first episode schizophrenia and healthy controls
Q87117734[Can long-term treatment with antipsychotic drugs lead to structural brain damage? Pro]
Q87945859[Frontal brain volume reduction due to antipsychotic drugs?]
Q45958384[Personalised medicine in psychiatry and psychotherapy. A review of the current state-of-the-art in the biomarker-based early recognition of psychoses].
Q89919164[Pros and cons of antipsychotic drugs in Prodromal stages of schizophrenia]
Q60621254[Somatic morbidity in the mentally ill]
Q50302553[The German research network for mental disorders].
Q89363812[What role for paraclinical investigations within clinical trials conducted in psychiatric patients?]

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