Impact of polygenic schizophrenia-related risk and hippocampal volumes on the onset of psychosis

scientific article published on 9 August 2016

Impact of polygenic schizophrenia-related risk and hippocampal volumes on the onset of psychosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/TP.2016.143
P932PMC publication ID5022088
P698PubMed publication ID27505231

P50authorAnita Riecher-RösslerQ550833
Tobias EgliQ57322239
Andreas PapassotiropoulosQ87015533
André SchmidtQ41595355
Stefan J BorgwardtQ43272535
P2093author name stringC Vogler
A E Simon
C Lenz
R Smieskova
F Harrisberger
P2860cites workA flexible and accurate genotype imputation method for the next generation of genome-wide association studiesQ21129496
Biological insights from 108 schizophrenia-associated genetic lociQ24561833
Genotype imputation with thousands of genomesQ24633967
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
Biomarkers for drug development in early psychosis: Current issues and promising directionsQ26752612
Stress effects on the hippocampus: a critical reviewQ26796713
Principal components analysis corrects for stratification in genome-wide association studiesQ27860975
Schizophrenia as a complex trait: evidence from a meta-analysis of twin studiesQ28190066
Common polygenic variation contributes to risk of schizophrenia and bipolar disorderQ28250609
Genome-wide association analysis identifies 13 new risk loci for schizophreniaQ28297287
Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-analysisQ31092643
Neuroimaging predictors of transition to psychosis--a systematic review and meta-analysis.Q33530424
Neuroanatomy of vulnerability to psychosis: a voxel-based meta-analysis.Q33775024
Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia.Q33814201
Schizophrenia severity, social functioning and hippocampal neuroanatomy: three-dimensional mapping studyQ33959553
Systematic meta-review and quality assessment of the structural brain alterations in schizophreniaQ34127541
Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.Q34255285
Cognitive functioning in prodromal psychosis: a meta-analysisQ34278910
Power and predictive accuracy of polygenic risk scores.Q34337027
Progressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies.Q34351095
Research review: Polygenic methods and their application to psychiatric traitsQ34434004
Common genetic variants influence human subcortical brain structuresQ34458961
Mapping the onset of psychosis: the Comprehensive Assessment of At-Risk Mental StatesQ34475129
Heritability of subcortical and limbic brain volume and shape in multiplex-multigenerational families with schizophreniaQ34585557
Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical riskQ34636460
Preventing a first episode of psychosis: meta-analysis of randomized controlled prevention trials of 12 month and longer-term follow-upsQ34654488
Genetic and environmental influences on neuroimaging phenotypes: a meta-analytical perspective on twin imaging studies.Q34919864
Long-term follow-up of a group at ultra high risk ("prodromal") for psychosis: the PACE 400 study.Q50706418
Efficacy of using cognitive status in predicting psychosis: a 7-year follow-up.Q51795265
The global burden of disease, 1990–2020Q53681952
A controlled study of brain structure in monozygotic twins concordant and discordant for schizophreniaQ57403363
Das Basel Screening Instrument für Psychosen (BSIP): Entwicklung, Aufbau, Reliabilität und ValiditätQ58896866
The Basel early-detection-of-psychosis (FEPSY)-study ? design and preliminary resultsQ58896933
Second-generation PLINK: rising to the challenge of larger and richer datasetsQ35125670
Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: evidence from two independent cohortsQ35221953
The hippocampo-prefrontal pathway: a possible therapeutic target for negative and cognitive symptoms of schizophreniaQ35222750
Hippocampal volume correlates with attenuated negative psychotic symptoms irrespective of antidepressant medicationQ35759415
A Bayesian model of shape and appearance for subcortical brain segmentationQ36158330
Neuroanatomical maps of psychosis onset: voxel-wise meta-analysis of antipsychotic-naive VBM studiesQ36386404
Genetic schizophrenia risk variants jointly modulate total brain and white matter volumeQ36612177
Phenotypic Manifestation of Genetic Risk for Schizophrenia During Adolescence in the General PopulationQ37258886
Polygenic determinants of white matter volume derived from GWAS lack reproducibility in a replicate sampleQ37621307
Hippocampal pathology in schizophrenia.Q37839953
The psychosis high-risk state: a comprehensive state-of-the-art reviewQ38061036
Towards indicated prevention of psychosis: using probabilistic assessments of transition risk in psychosis prodromeQ38260578
Hippocampal volume change relates to clinical outcome in childhood-onset schizophreniaQ39011523
Different duration of at-risk mental state associated with neurofunctional abnormalities. A multimodal imaging studyQ39289853
Prognosis of Brief Psychotic Episodes: A Meta-analysis.Q40110736
Prediction of psychosis. A step towards indicated prevention of schizophrenia.Q40840671
Bayesian mediation analysisQ41051811
Improved whole-chromosome phasing for disease and population genetic studiesQ44584387
Neuroanatomical markers of genetic liability to psychosis and first episode psychosis: a voxelwise meta-analytical comparisonQ46146851
Hippocampal volumes in schizophrenic twinsQ46211788
A twin study of genetic contributions to hippocampal morphology in schizophreniaQ46519005
Brain volumes in relatives of patients with schizophrenia: a meta-analysisQ48252424
Hippocampus and amygdala in schizophrenia: assessment of the relationship of neuroanatomy to psychopathologyQ48693683
Brain MRI abnormalities in schizophrenia: same genes or same environment?Q48767848
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P921main subjectschizophreniaQ41112
P304page(s)e868
P577publication date2016-08-09
P1433published inTranslational PsychiatryQ15716636
P1476titleImpact of polygenic schizophrenia-related risk and hippocampal volumes on the onset of psychosis
P478volume6

Reverse relations

cites work (P2860)
Q41535850Age-related brain structural alterations as an intermediate phenotype of psychosis
Q92667458Association of antidepressants with brain morphology in early stages of psychosis: an imaging genomics approach
Q90209906Do cognitive and neuropsychological functioning deficits coincide with hippocampal alteration during first-psychotic episode?
Q94599682Hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated psychosis
Q92238319Imaging Genetics Towards a Refined Diagnosis of Schizophrenia
Q59335564Is It Possible to Predict the Future in First-Episode Psychosis?
Q47550318MRI Indices of Cortical Development in Young People With Psychotic Experiences: Influence of Genetic Risk and Persistence of Symptoms.
Q52630895Polygenic Risk Scores in Clinical Psychology: Bridging Genomic Risk to Individual Differences.
Q91235313Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients
Q40144031Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia
Q52691528Thalamic Reticular Dysfunction as a Circuit Endophenotype in Neurodevelopmental Disorders.
Q61806070Treating the "E" in "G × E": Trauma-Informed Approaches and Psychological Therapy Interventions in Psychosis
Q49974926Verbal learning and hippocampal dysfunction in schizophrenia: A meta-analysis.

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