Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR

scientific article

Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR is …
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scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.2011739
P8608Fatcat IDrelease_fparrcjqcraw7dkm3uz7xlr6ae
P3181OpenCitations bibliographic resource ID1781375
P698PubMed publication ID2011739

P50authorAnne GatignolQ47252183
P2093author name stringK T Jeang
B Berkhout
A Buckler-White
P433issue5001
P407language of work or nameEnglishQ1860
P921main subjectHIVQ15787
RNA-binding proteinsQ3928341
P304page(s)1597-600
P577publication date1991-03-29
P1433published inScienceQ192864
P1476titleCharacterization of a human TAR RNA-binding protein that activates the HIV-1 LTR
P478volume251

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cites work (P2860)
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Q38293063Human immunodeficiency virus type 1 TAR element revertant viruses define RNA structures required for efficient viral gene expression and replication
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Q36690014In memoriam: Kuan-Teh Jeang, MD PhD (1958-2013)
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Q35273064TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR
Q40046655TAR loop-dependent human immunodeficiency virus trans activation requires factors encoded on human chromosome 12.
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Q64245900TARBP2-Enhanced Resistance during Tamoxifen Treatment in Breast Cancer
Q64113617TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma
Q27310145TRBP and eIF6 homologue in Marsupenaeus japonicus play crucial roles in antiviral response
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Q38973401TRBP maintains mammalian embryonic neural stem cell properties by acting as a novel transcriptional coactivator of the Notch signaling pathway
Q24306121TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
Q24320260TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
Q89684927TRBP-Dicer interaction may enhance HIV-1 TAR RNA translation via TAR RNA processing, repressing host-cell apoptosis
Q24317387TRIP: a novel double stranded RNA binding protein which interacts with the leucine rich repeat of flightless I
Q92240525Tat IRES modulator of tat mRNA (TIM-TAM): a conserved RNA structure that controls Tat expression and acts as a switch for HIV productive and latent infection
Q41868116Tat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1.
Q34033142Tat as a transcriptional activator and a potential therapeutic target for HIV-1.
Q42636277The 2008 Retrovirology Prize: Ben Berkhout and his RNA world
Q41510614The 5' UTR of HIV-1 full-length mRNA and the Tat viral protein modulate the programmed -1 ribosomal frameshift that generates HIV-1 enzymes
Q24534342The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)
Q39097882The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication
Q24320118The RNA-binding region of human TRBP interacts with microRNA precursors through two independent domains
Q56794989The TAR RNA-binding Protein, TRBP, Stimulates the Expression of TAR-containing RNAsin Vitroandin VivoIndependently of Its Ability to Inhibit the dsRNA-dependent Kinase PKR
Q40479603The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection.
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Q43459638The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity
Q38960851The cellular TAR RNA binding protein, TRBP, promotes HIV-1 replication primarily by inhibiting the activation of double-stranded RNA-dependent kinase PKR.
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Q74450822The gene encoding PRBP, the mouse homolog of human TRBP, maps to distal chromosome 15
Q40597354The human immunodeficiency virus type-1 long terminal repeat and its role in gene expression
Q34505284The interplay between virus infection and the cellular RNA interference machinery
Q36697616The mouse antiphosphotyrosine immunoreactive kinase, TIK, is indistinguishable from the double-stranded RNAdependent, interferon-induced protein kinase, PKR
Q36194939The multiple functions of TRBP, at the hub of cell responses to viruses, stress, and cancer
Q35896506The sequence and structure of the 3' arm of the first stem-loop of the human immunodeficiency virus type 2 trans-activation responsive region mediate Tat-2 transactivation.
Q34462285The single-stranded DNA binding protein, Pur-alpha, binds HIV-1 TAR RNA and activates HIV-1 transcription
Q36499148Tombusvirus P19 RNA silencing suppressor (RSS) activity in mammalian cells correlates with charged amino acids that contribute to direct RNA-binding
Q33565167Transcriptional Gene Silencing (TGS) via the RNAi Machinery in HIV-1 Infections
Q27480847Translation elongation factor-1 alpha interacts with the 3' stem-loop region of West Nile virus genomic RNA
Q34114862Translational control in vertebrate development
Q36708965Translational control of retroviruses.
Q36012262Trbp Is Required for Differentiation of Myoblasts and Normal Regeneration of Skeletal Muscle
Q35798130Trbp regulates heart function through microRNA-mediated Sox6 repression
Q28204738Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression
Q34134540Unperturbed posttranscriptional regulatory Rev protein function and HIV-1 replication in astrocytes
Q39021524Up-regulation and worse prognostic marker of cytoplasmic TARBP2 expression in obstinate breast cancer
Q37800635Viral RNA silencing suppressors (RSS): Novel strategy of viruses to ablate the host RNA interference (RNAi) defense system
Q57810083Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells
Q38787648Visualizing repetitive diffusion activity of double-strand RNA binding proteins by single molecule fluorescence assays
Q41984284Xlrbpa, a double-stranded RNA-binding protein associated with ribosomes and heterogeneous nuclear RNPs
Q35864679cis-acting elements in human immunodeficiency virus type 1 RNAs direct viral transcripts to distinct intranuclear locations.
Q36342076siRNA, miRNA and HIV: promises and challenges

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