Trbp regulates heart function through microRNA-mediated Sox6 repression

scientific article published on June 2015

Trbp regulates heart function through microRNA-mediated Sox6 repression is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NG.3324
P8608Fatcat IDrelease_gytaindl7jcftfiagbicdgdm74
P932PMC publication ID4485565
P698PubMed publication ID26029872

P50authorJian DingQ42910577
Zhiqiang LinQ56998519
P2093author name stringLixin Ma
Da-Zhi Wang
Xiaoyun Hu
Mao Nie
Zhong-Liang Deng
Yanqun Wang
Jinghai Chen
Masaharu Kataoka
Pingzhu Zhou
William T Pu
P2860cites workTRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencingQ24306121
Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathyQ24314590
TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencingQ24320260
Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathyQ24562178
Hopx and Hdac2 Interact to Modulate Gata4 Acetylation and Embryonic Cardiac Myocyte ProliferationQ24597593
Relatedness of an RNA-binding motif in human immunodeficiency virus type 1 TAR RNA-binding protein TRBP to human P1/dsI kinase and Drosophila staufenQ24606166
Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6Q24607540
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failureQ24648103
MicroRNAs in stress signaling and human diseaseQ27027517
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene listsQ28131785
Hop is an unusual homeobox gene that modulates cardiac developmentQ28203645
Myosin light chain mutation causes autosomal recessive cardiomyopathy with mid-cavitary hypertrophy and restrictive physiologyQ28218408
Congenital myopathy with nemaline rods and cap structures caused by a mutation in the beta-tropomyosin gene (TPM2)Q28248133
A mutation in the fast skeletal muscle troponin I gene causes myopathy and distal arthrogryposisQ28259210
Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTRQ28271896
Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin CQ28284750
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2Q28295844
A mutation in the alpha tropomyosin gene TPM3 associated with autosomal dominant nemaline myopathyQ28299243
Modulation of cardiac growth and development by HOP, an unusual homeodomain proteinQ28507581
Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophyQ28565486
A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cellsQ28586085
An essential role of Bmp4 in the atrioventricular septation of the mouse heartQ28586261
Control of stress-dependent cardiac growth and gene expression by a microRNAQ28587851
mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult heartsQ28594889
Efficient in vivo manipulation of mouse genomic sequences at the zygote stageQ29547306
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesisQ29547607
Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAsQ29618428
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performanceQ29619547
microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart.Q30090181
microRNA-138 modulates cardiac patterning during embryonic development.Q30484543
Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathyQ33853875
Elevated miR-499 levels blunt the cardiac stress responseQ33900451
Coexistence of cardiac troponin T variants reduces heart efficiencyQ33994922
Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6.Q34045389
Complexity of the microRNA repertoire revealed by next-generation sequencingQ34140539
Pervasive roles of microRNAs in cardiovascular biologyQ34775686
Chronic coexistence of two troponin T isoforms in adult transgenic mouse cardiomyocytes decreased contractile kinetics and caused dilatative remodelingQ36114673
TRBP alters human precursor microRNA processing in vitroQ36342240
Dicer partner proteins tune the length of mature miRNAs in flies and mammalsQ36718965
MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stressQ37038566
Regulation of cardiac microRNAs by cardiac microRNAsQ37162692
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice.Q37328435
A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcomaQ39331421
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heartQ40036277
Growth and hypertrophy of the heart: towards an understanding of cardiac specific and inducible gene expressionQ40786533
Homeodomain only protein x is down-regulated in human heart failureQ41860424
Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI modelQ41994688
Deletion of human tarbp2 reveals cellular microRNA targets and cell-cycle function of TRBP.Q53000083
Heart failure: advances through genomicsQ83667474
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
P304page(s)776-783
P577publication date2015-06-01
P1433published inNature GeneticsQ976454
P1476titleTrbp regulates heart function through microRNA-mediated Sox6 repression
P478volume47

Reverse relations

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