Tachykinins and tachykinin receptors: structure and activity relationships

scientific article

Tachykinins and tachykinin receptors: structure and activity relationships is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.2174/0929867043364748
P3181OpenCitations bibliographic resource ID580101
P698PubMed publication ID15279567
P5875ResearchGate publication ID8429530

P50authorMariano HernándezQ28605059
Pedro M NietoQ52862822
Teresa A AlmeidaQ60547938
P2093author name stringJ Rojo
F M Pinto
P M Nieto
J D Martín
M L Candenas
P2860cites workChemical shifts as a tool for structure determinationQ40576242
P433issue15
P407language of work or nameEnglishQ1860
P921main subjecttachykinin receptorQ426034
P304page(s)2045-2081
P577publication date2004-08-01
P1433published inCurrent Medicinal ChemistryQ3007710
P1476titleTachykinins and tachykinin receptors: structure and activity relationships
P478volume11

Reverse relations

cites work (P2860)
Q40893810A Direct Neurokinin B Projection from the Arcuate Nucleus Regulates Magnocellular Vasopressin Cells of the Supraoptic Nucleus
Q37790485A decade of progress in the discovery and development of 'atypical' antipsychotics
Q35049408A population of kisspeptin/neurokinin B neurons in the arcuate nucleus may be the central target of the male effect phenomenon in goats
Q36319631An involvement of neurokinin-1 receptor in FcεRΙ-mediated RBL-2H3 mast cell activation
Q40756083Analysis of the Expression of Tachykinins and Tachykinin Receptors in the Rat Uterus During Early Pregnancy.
Q47141491Aprepitant for the Treatment of Chronic Refractory Pruritus.
Q34114183Autocrine regulation of human sperm motility by tachykinins
Q26784074Biological and Pharmacological Aspects of the NK1-Receptor
Q34588695Characterization of RO4583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK₁ and NK₃ receptors
Q28570413Chronic methamphetamine exposure suppresses the striatal expression of members of multiple families of immediate early genes (IEGs) in the rat: normalization by an acute methamphetamine injection
Q90411741Crystal structure of the human NK1 tachykinin receptor
Q39787316Design, Synthesis, and Optimization of Balanced Dual NK1/NK3 Receptor Antagonists
Q50086799Disruption of the neurokinin-3 receptor (NK3) in mice leads to cognitive deficits.
Q46490051Distribution of prolyl oligopeptidase in the mouse whole-body sections and peripheral tissues.
Q80338320Distribution pattern of tachykinin NK2 receptors in human colon: involvement in the regulation of intestinal motility
Q38189272Drug-target residence time--a case for G protein-coupled receptors
Q38965246Effect of truncated neurokinin-1 receptor expression changes on the interaction between human breast cancer and bone marrow-derived mesenchymal stem cells
Q35161008Effects of intravenous administration of neurokinin receptor subtype-selective agonists on gonadotropin-releasing hormone pulse generator activity and luteinizing hormone secretion in goats
Q37634265Effects of neurokinin B administration on reproductive hormone secretion in healthy men and women
Q47813007Enhancement of Gustatory Neural Responses by Parasympathetic Nerve in the Frog.
Q57357252Evidence for a role of caveolin-1 in neurokinin-1 receptor plasma-membrane localization, efficient signaling, and interaction with β-arrestin 2
Q35613975Evidence from the agonadal juvenile male rhesus monkey (Macaca mulatta) for the view that the action of neurokinin B to trigger gonadotropin-releasing hormone release is upstream from the kisspeptin receptor
Q34221590Expression and function of human hemokinin-1 in human and guinea pig airways
Q44522502Expression of neurokinin B/NK3 receptor and kisspeptin/KISS1 receptor in human granulosa cells.
Q34962059GPCR Heterodimerization in the Reproductive System: Functional Regulation and Implication for Biodiversity
Q61798028Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography
Q92620158IGFs Potentiate TAC3-induced SLα Expression via Upregulation of TACR3 Expression in Grass Carp Pituitary Cells
Q42862529In vitroassessment of metabolic drug–drug interaction potential of AZD2624, neurokinin-3 receptor antagonist, through cytochrome P450enzyme identification, inhibition, and induction studies
Q36439417Increased neurokinin B (Tac2) expression in the mouse arcuate nucleus is an early marker of pubertal onset with differential sensitivity to sex steroid-negative feedback than Kiss1.
Q28288195Interactions between kisspeptins and neurokinin B
Q33556294Involvement of L-selectin in contact hypersensitivity responses augmented by auditory stress
Q36756393Involvement of neuropeptide systems in schizophrenia: human studies
Q37617971Involvement of substance P and the NK-1 receptor in pancreatic cancer
Q35159620Knockout of the neurokinin-1 receptor reduces cholangiocyte proliferation in bile duct-ligated mice
Q38771632Looking forward to new targeted treatments for chronic spontaneous urticaria
Q47102783Mapping of KNDy neurons and immunohistochemical analysis of the interaction between KNDy and substance P neural systems in goat
Q46976681Membrane associated functions of neurokinin B (NKB) on Abeta (25-35) induced toxicity in aging rat brain synaptosomes
Q46511589Mouse Hemokinin-1 Decapeptide Subjected to a Brain-specific Post-translational Modification
Q37017449Mutational analysis of TAC3 and TACR3 genes in patients with idiopathic central pubertal disorders
Q46627333NK3 receptors mediate an increase in firing rate of midbrain dopamine neurons of the rat and the guinea pig.
Q27664966NMR evidence of GM1-induced conformational change of Substance P using isotropic bicelles
Q46257087Neurogenic mediators contribute to local edema induced by Micrurus lemniscatus venom
Q38244712Neurokinin B and reproductive functions: "KNDy neuron" model in mammals and the emerging story in fish
Q34354034Neurokinin B and the hypothalamic regulation of reproduction
Q28749270Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus
Q36069004Neurokinin Bs and neurokinin B receptors in zebrafish-potential role in controlling fish reproduction
Q34150798Neurokinin-1 receptor: functional significance in the immune system in reference to selected infections and inflammation
Q57810982Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K channel
Q42477734Neurokinin2‐R in medial septum regulate hippocampal and amygdalar ACh release induced by intraseptal application of neurokinins A and B
Q38857829Neuropeptide derivatives to regulate the reproductive axis: Kisspeptin receptor (KISS1R) ligands and neurokinin-3 receptor (NK3R) ligands
Q37492012Neuropeptide receptors as potential drug targets in the treatment of inflammatory conditions
Q26768672New Prognostic Biomarkers in Patients With Traumatic Brain Injury
Q57482211New prognostic biomarkers of mortality in patients undergoing liver transplantation for hepatocellular carcinoma
Q28286127Opinion: NK3 receptor antagonists: the next generation of antipsychotics?
Q37299308Ovarian steroids regulate tachykinin and tachykinin receptor gene expression in the mouse uterus
Q39017962Overexpression of membrane metalloendopeptidase inhibits substance P stimulation of cholangiocarcinoma growth
Q38792249Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene.
Q55003470Patients with high serum substance P levels previously to liver transplantation for hepatocellular carcinoma have higher risk of one-year liver transplantation mortality.
Q92819311Persistently High Serum Substance P Levels and Early Mortality in Patients with Severe Traumatic Brain Injury
Q35546454Prenatal testosterone excess decreases neurokinin 3 receptor immunoreactivity within the arcuate nucleus KNDy cell population
Q55076872Pruritus: Progress toward Pathogenesis and Treatment.
Q46791806Qualitative and quantitative analysis of tachykinin NK2 receptors in chemically defined human colonic neuronal pathways
Q36506401Recognition of GPCRs by peptide ligands and membrane compartments theory: structural studies of endogenous peptide hormones in membrane environment
Q37261419Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats
Q40684887Serum Levels of Substance P and Mortality in Patients with a Severe Acute Ischemic Stroke
Q35584890Serum substance P levels are associated with severity and mortality in patients with severe traumatic brain injury
Q33235331Specificity of a Vibrio vulnificus aminopeptidase toward kinins and other peptidyl substrates
Q39273907Sputum neurokinin A in Egyptian asthmatic children and adolescents: relation to exacerbation severity
Q87932936Substance P and Antagonists of the Neurokinin-1 Receptor in Neuroinflammation Associated with Infectious and Neurodegenerative Diseases of the Central Nervous System
Q42525242Substance P depolarizes striatal projection neurons and facilitates their glutamatergic inputs
Q42452231Substance P mediates excitatory interactions between striatal projection neurons
Q30436640Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependence
Q41182975Sustained Low Serum Substance P Levels in Non-Surviving Septic Patients
Q50774843Synthesis of new 4-heteroaryl-2-phenylquinolines and their pharmacological activity as NK-2/NK-3 receptor ligands.
Q34902985TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction
Q33984838TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood
Q33733130TGF-beta regulates T-cell neurokinin-1 receptor internalization and function
Q34171734Tachykinin neurokinin 3 receptor antagonists: a patent review (2005 - 2010).
Q37638682Tachykinin receptor antagonists in clinical trials
Q34147318Tachykinin receptor assays.
Q55334465Tachykinin-3 Genes and Peptides Characterized in a Basal Teleost, the European Eel: Evolutionary Perspective and Pituitary Role.
Q92445562Tachykinins and Kisspeptins in the Regulation of Human Male Fertility
Q37769121Tachykinins and Neurokinin Receptors in Bone Marrow Functions: Neural-Hematopoietic Link
Q91866904Tachykinins: Neuropeptides That Are Ancient, Diverse, Widespread and Functionally Pleiotropic
Q37827172Targeted treatment of pruritus: a look into the future
Q41093430Targeting neurokinin-3 receptor: a novel anti-angiogenesis strategy for cancer treatment
Q28751738Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy
Q46528981The levels of blood mercury and inflammatory-related neuropeptides in the serum are correlated in children with autism spectrum disorder
Q34259043The mammalian tachykinin ligand-receptor system: an emerging target for central neurological disorders
Q48727907The neurokinin B pathway in human reproduction
Q35682478The possible link between the elevated serum levels of neurokinin A and anti-ribosomal P protein antibodies in children with autism
Q34354198The role and potential sites of action of thyroid hormone in timing the onset of puberty in male primates
Q58914868The role of neurokinin-1 receptor in the microenvironment of inflammation and cancer
Q37235656The tachykinin peptide neurokinin B binds copper forming an unusual [CuII(NKB)2] complex and inhibits copper uptake into 1321N1 astrocytoma cells
Q48463949Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.
Q64086770Treatment-resistant prurigo nodularis: challenges and solutions
Q49972918Truncation of neurokinin-1 receptor-Negative regulation of substance P signaling
Q38095597Understanding the pathophysiology of itch

Search more.