Neurokinin B and reproductive functions: "KNDy neuron" model in mammals and the emerging story in fish

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Neurokinin B and reproductive functions: "KNDy neuron" model in mammals and the emerging story in fish is …
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P356DOI10.1016/J.YGCEN.2014.08.009
P698PubMed publication ID25172151

P50authorCheng-Yuan LinQ56951621
Anderson O L WongQ59708585
P2093author name stringMulan He
Guangfu Hu
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Neurokinin B and pre-eclampsia: a decade of discoveryQ21245537
Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic OrganizationQ22065873
Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsiaQ22254337
Characterization of the endokinins: Human tachykinins with cardiovascular activityQ24674629
The role of neurokinin B signalling in reproductive neuroendocrinologyQ26865477
Solution structure of the tachykinin peptide eledoisinQ27640297
Tachykinins and tachykinin receptors: a growing familyQ28239267
Gene regulation of neurokinin B and its receptor NK3 in late pregnancy and pre-eclampsiaQ28241073
Tachykinins and tachykinin receptors: structure and activity relationshipsQ28274228
Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretionQ28283342
Interactions between kisspeptins and neurokinin BQ28288195
Tachykinins: receptor to effectorQ28297263
dynorphin-kappa opioid receptor signaling partly mediates estrogen negative feedback effect on LH pulses in female ratsQ28570263
Involvement of anteroventral periventricular metastin/kisspeptin neurons in estrogen positive feedback action on luteinizing hormone release in female ratsQ28575729
Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterusQ28594544
Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleusQ28749270
Overview of the Primary Structure, Tissue-Distribution, and Functions of Tachykinins and their ReceptorsQ29029923
Profile of neurokinin B concentrations in maternal and cord blood in normal pregnancyQ29040192
The tachykinin NK1 receptor. Part I: Ligands and mechanisms of cellular activationQ29306227
Activation of neurokinin 3 receptors stimulates GnRH release in a location-dependent but kisspeptin-independent manner in adult miceQ30409753
Arcuate kisspeptin/neurokinin B/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weightQ30419024
Uncovering novel reproductive defects in neurokinin B receptor null mice: closing the gap between mice and men.Q30422142
Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouseQ30424215
Characterisation of arcuate nucleus kisspeptin/neurokinin B neuronal projections and regulation during lactation in the rat.Q30429153
Forebrain projections of arcuate neurokinin B neurons demonstrated by anterograde tract-tracing and monosodium glutamate lesions in the rat.Q30432921
Characterization of the Sialokinin I gene encoding the salivary vasodilator of the yellow fever mosquito, Aedes aegyptiQ30830328
Expression and functional characterization of a Drosophila neuropeptide precursor with homology to mammalian preprotachykinin A.Q30868764
Two tachykinin-like peptides from skin secretions of Danio rerioQ30953045
Placental neurokinin B mRNA expression increases at preterm labor.Q50336757
The inhibitory effects of neurokinin B on GnRH pulse generator frequency in the female rat.Q51385117
Pharmacology of stomoxytachykinin receptor depends on second messenger system.Q52654297
Substance P-induced inhibition of Leydig cell steroidogenesis in primary cultureQ67711391
Neurokinin B gene expression is increased in the arcuate nucleus of ovariectomized ratsQ71668975
Presence of nuclear androgen receptor-like immunoreactivity in neurokinin B-containing neurons of the hypothalamic arcuate nucleus of the adult male ratQ72153790
Dual label in situ hybridization studies provide evidence that luteinizing hormone-releasing hormone neurons do not synthesize messenger ribonucleic acid for mu, kappa, or delta opiate receptorsQ73167204
Identification of neurokinin B-expressing neurons as an highly estrogen-receptive, sexually dimorphic cell group in the ovine arcuate nucleusQ73218587
Neurokinin B levels in maternal and umbilical cord blood in preeclamptic and normal pregnanciesQ80268180
Tachykinin family genes and their receptors are differentially expressed in the hypothyroid ovary and pituitaryQ80971297
Coexpression of preprotachykinin A and B transcripts in the bovine corpus luteum and evidence for functional neurokinin receptor activity in luteal endothelial cells and ovarian macrophagesQ81103379
Speciation of polyploid Cyprinidae fish of common carp, crucian carp, and silver crucian carp derived from duplicated Hox genesQ84717510
Molecular modeling of neurokinin B and tachykinin NK₃ receptor complexQ95384808
Evidence of a role for kisspeptin and neurokinin B in puberty of female sheepQ35986104
Neurokinin Bs and neurokinin B receptors in zebrafish-potential role in controlling fish reproductionQ36069004
The evolution of neuroendocrine peptidesQ36111183
Expression divergence between duplicate genesQ36248335
KNDy (kisspeptin/neurokinin B/dynorphin) neurons are activated during both pulsatile and surge secretion of LH in the ewe.Q36323170
Prolactin and growth hormone in fish osmoregulationQ36365598
Neurokinin B and the control of the gonadotropic axis in the rat: developmental changes, sexual dimorphism, and regulation by gonadal steroids.Q36439366
Increased neurokinin B (Tac2) expression in the mouse arcuate nucleus is an early marker of pubertal onset with differential sensitivity to sex steroid-negative feedback than Kiss1.Q36439417
Role of neurokinin B in the control of female puberty and its modulation by metabolic statusQ36595730
Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neuronsQ36660601
Synchronous activation of gonadotropin-releasing hormone gene transcription and secretion by pulsatile kisspeptin stimulationQ36747469
Tachykinins and their functions in the gastrointestinal tract.Q36977607
Regulation of arcuate neurons coexpressing kisspeptin, neurokinin B, and dynorphin by modulators of neurokinin 3 and κ-opioid receptors in adult male miceQ37018552
Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat.Q37174107
Kisspeptin, neurokinin B, and dynorphin act in the arcuate nucleus to control activity of the GnRH pulse generator in ewesQ37240188
The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complexQ37273521
Ovarian steroids regulate tachykinin and tachykinin receptor gene expression in the mouse uterusQ37299308
Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouseQ37475488
Kisspeptin restores pulsatile LH secretion in patients with neurokinin B signaling deficiencies: physiological, pathophysiological and therapeutic implicationsQ37518722
Tachykinin-related peptides and their receptors in invertebrates: a current view.Q37603521
A role for neurokinin B in pulsatile GnRH secretion in the ewe.Q37685929
Neurokinin B signaling in puberty: human and animal studiesQ37696650
Tachykinins and the hypothalamo-pituitary-gonadal axis: An updateQ37908266
Neurokinin B signalling in the human reproductive axisQ37909571
Insight into molecular and functional diversity of tachykinins and their receptorsQ38013144
Mini-review: the evolution of neuropeptide signalingQ38021017
Anatomy of the kisspeptin systems in teleosts.Q38042518
Sex steroid regulation of kisspeptin circuits.Q38095411
The role of prolactin in fish reproductionQ38116259
Molecular recognition of tachykinin receptor selective agonists: insights from structural studiesQ38128359
The effects of the members of growth hormone family knockdown in zebrafish developmentQ38307122
Analysis of the expression of neurokinin B, kisspeptin, and their cognate receptors NK3R and KISS1R in the human female genital tractQ38404701
Role of Neurokinin B and Dynorphin A in pituitary gonadotroph and somatolactotroph cell linesQ39341027
Differentially regulated expression of neurokinin B (NKB)/NK3 receptor system in uterine leiomyomataQ39422495
Recombinant aequorin as a reporter for receptor-mediated changes of intracellular Ca2+ -levels in Drosophila S2 cellsQ40682716
Functional analysis of synthetic insectatachykinin analogs on recombinant neurokinin receptor expressing cell linesQ40690178
The neurokinin A receptor activates calcium and cAMP responses through distinct conformational statesQ40791665
Characterization of a receptor for insect tachykinin-like peptide agonists by functional expression in a stable Drosophila Schneider 2 cell lineQ40881469
Functional coupling of the NK1 tachykinin receptor to phospholipase D in chinese hamster ovary cells and astrocytoma cells.Q41046267
Truncated, desensitization-defective neurokinin receptors mediate sustained MAP kinase activation, cell growth and transformation by a Ras-independent mechanism.Q41075127
Where does amidation take place?Q41265097
Substance P and related tachykinins induce receptor-mediated hydrolysis of polyphosphoinositides in the rat anterior pituitaryQ41879098
A role for tachykinins in the regulation of human sperm motility.Q42152326
A novel biological role of tachykinins as an up-regulator of oocyte growth: identification of an evolutionary origin of tachykininergic functions in the ovary of the ascidian, Ciona intestinalisQ42436156
Evidence that dynorphin plays a major role in mediating progesterone negative feedback on gonadotropin-releasing hormone neurons in sheepQ42457788
Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat.Q42467752
Multiple mechanisms of arachidonic acid release in Chinese hamster ovary cells transfected with cDNA of substance P receptorQ42476717
Tachykinins induce secretion of prolactin from perifused rat anterior pituitary cells by interactions with two different binding sitesQ42526626
In vitro effects of substance P and arginine-vasopressin on testosterone production in Leydig cells of short and long photoperiodic hamsters.Q42529013
Characterization of a novel cDNA sequence encoding invertebrate tachykinin-related peptides isolated from the echiuroid worm, Urechis unicinctusQ42611286
Chemical transmission in the sea anemone Nematostella vectensis: A genomic perspectiveQ43093250
TAC3 and TACR3 defects cause hypothalamic congenital hypogonadotropic hypogonadism in humansQ43145611
Kisspeptin neurons in the ovine arcuate nucleus and preoptic area are involved in the preovulatory luteinizing hormone surge.Q43263801
Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice.Q43435526
Novel pituitary actions of TAC3 gene products in fish model: receptor specificity and signal transduction for prolactin and somatolactin α regulation by neurokinin B (NKB) and NKB-related peptide in carp pituitary cells.Q43538993
Whole genome duplication: challenges and considerations associated with sequence orthology assignment in SalmoninaeQ43564977
Changes in the expression of tachykinin receptors in the rat uterus during the course of pregnancyQ43683562
Binding of an iodinated substance P analogue to cultured anterior pituitary prolactin- and luteinizing hormone-containing cellsQ43769553
The evolution of tachykinin/tachykinin receptor (TAC/TACR) in vertebrates and molecular identification of the TAC3/TACR3 system in zebrafish (Danio rerio).Q44018628
Mutations in the extracellular amino-terminal domain of the NK2 neurokinin receptor abolish cAMP signaling but preserve intracellular calcium responsesQ44107300
Colocalization of progesterone receptors in parvicellular dynorphin neurons of the ovine preoptic area and hypothalamusQ44193786
Suppression of the GnRH pulse generator by neurokinin B involves a κ-opioid receptor-dependent mechanismQ44335610
Presence of mu and kappa opioid receptor mRNAs in galanin but not in GnRH neurons in the female rat.Q44347036
A role for tachykinins in female mouse and rat reproductive functionQ44457738
Characterization of tachykinin NK2 receptor in the anterior pituitary glandQ44572631
Estrogen Regulation of Neurokinin B Gene Expression in the Mouse Arcuate Nucleus Is Mediated by Estrogen Receptor αQ44639177
Cloning of somatolactin alpha and beta cDNAs in zebrafish and phylogenetic analysis of two distinct somatolactin subtypes in fish.Q44898718
Transcripts of neurokinin B and neurokinin 3 receptor in superovulated rat ovaries and increased number of corpora lutea as a non-specific effect of intraperitoneal agonist applicationQ45068904
Effect of substance P on venous tone in conscious ratsQ45197818
Grass carp somatolactin: I. Evidence for PACAP induction of somatolactin-alpha and -beta gene expression via activation of pituitary PAC-I receptors.Q45950664
Differential regulation of KiSS-1 mRNA expression by sex steroids in the brain of the male mouseQ46438750
Isolation and characterization of novel tachykinins from the posterior salivary gland of the common octopus Octopus vulgarisQ46522116
Neurokinin B activates arcuate kisspeptin neurons through multiple tachykinin receptors in the male mouseQ46563783
Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminenceQ46605330
Organization of two independent kisspeptin systems derived from evolutionary-ancient kiss genes in the brain of zebrafish.Q47321002
Cloning and expression of tachykinins and their association with kisspeptins in the brains of zebrafishQ48003730
A novel tachykinin-related peptide receptor of Octopus vulgaris--evolutionary aspects of invertebrate tachykinin and tachykinin-related peptideQ48080266
Tachykinin and tachykinin receptor of an ascidian, Ciona intestinalis: evolutionary origin of the vertebrate tachykinin familyQ48168182
Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeysQ48174465
Hypothalamic Kiss1 but not Kiss2 neurons are involved in estrogen feedback in medaka (Oryzias latipes).Q48281445
KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season.Q48329788
The effects of neurokinin B upon gonadotrophin release in male rodents.Q48361192
Spontaneous kisspeptin neuron firing in the adult mouse reveals marked sex and brain region differences but no support for a direct role in negative feedback.Q48371770
Coexpression of dynorphin and neurokinin B immunoreactivity in the rat hypothalamus: Morphologic evidence of interrelated function within the arcuate nucleusQ48443918
Sexual dimorphism in the organization of the rat hypothalamic infundibular areaQ48483225
Estradiol acts locally within the retrochiasmatic area to inhibit pulsatile luteinizing-hormone release in the female sheep during anestrusQ48702050
Substance P increases intracellular Ca2+ in individual rat pituitary lactotrophs, somatotrophs, and gonadotrophsQ48802200
Genome evolution and biodiversity in teleost fishQ33211247
Substance P inhibits progesterone conversion to neuroactive metabolites in spinal sensory circuit: a potential component of nociceptionQ33216935
Tachykinin-related peptide precursors in two cockroach speciesQ33217878
Amphibian tachykinin precursorQ33260584
Cloning and expression of kiss2 in the zebrafish and medakaQ33377387
Rapidly evolving fish genomes and teleost diversityQ33394488
Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the ratQ33519061
The kisspeptin/neurokinin B/dynorphin (KNDy) cell population of the arcuate nucleus: sex differences and effects of prenatal testosterone in sheepQ33577509
Neurokinin 3 receptor immunoreactivity in the septal region, preoptic area and hypothalamus of the female sheep: colocalisation in neurokinin B cells of the arcuate nucleus but not in gonadotrophin-releasing hormone neurones.Q33652453
Effects of tachykinins on uterine smooth muscleQ34079159
Autocrine regulation of human sperm motility by tachykininsQ34114183
Modulation of the fish immune system by hormones.Q34117548
Neurokinin B acts via the neurokinin-3 receptor in the retrochiasmatic area to stimulate luteinizing hormone secretion in sheepQ34132446
Neurokinin B Is a Paracrine Vasodilator in the Human Fetal Placental CirculationQ34194431
mRNA expression of tachykinins and tachykinin receptors in different human tissuesQ34328601
Hemokinins and endokininsQ34329882
Neurokinin B and the hypothalamic regulation of reproductionQ34354034
Neurokinin-3 receptor activation in the retrochiasmatic area is essential for the full pre-ovulatory luteinising hormone surge in ewes.Q34364194
Minireview: kisspeptin neurons as central processors in the regulation of gonadotropin-releasing hormone secretionQ34479046
Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alphaQ34514612
Tachykinins and tachykinin receptors in the gut, with special reference to NK2 receptors in humanQ34566552
Tachykinins in the immune systemQ34570153
Rapid subfunctionalization accompanied by prolonged and substantial neofunctionalization in duplicate gene evolutionQ34570892
Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cellsQ34737724
TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproductionQ34902985
Sialokinin I and II: vasodilatory tachykinins from the yellow fever mosquito Aedes aegyptiQ34908492
Hypogonadotropic hypogonadism due to a novel missense mutation in the first extracellular loop of the neurokinin B receptor.Q35014404
Tachykinins and tachykinin receptors in human uterusQ35045379
Substance P increases neutrophil adhesion to human umbilical vein endothelial cellsQ35045505
Substance P-immunoreactive cells in the ovine pars tuberalisQ35121089
Growth hormone and prolactin--molecular and functional evolutionQ35129346
Insight into tachykinin-related peptides, their receptors, and invertebrate tachykinins: a reviewQ35141544
Peripheral tachykinin receptors as potential therapeutic targets in visceral diseasesQ35143893
Mammalian tachykinins and uterine smooth muscle: the challenge escalatesQ35908478
New insights into the control of pulsatile GnRH release: the role of Kiss1/neurokinin B neuronsQ35971603
P304page(s)94-108
P577publication date2014-08-27
P1433published inGeneral and Comparative EndocrinologyQ15716702
P1476titleNeurokinin B and reproductive functions: "KNDy neuron" model in mammals and the emerging story in fish
P478volume208

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cites work (P2860)
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