Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth

scientific article

Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/PATH.2343
P3181OpenCitations bibliographic resource ID948810
P698PubMed publication ID18393365

P50authorRoberto CappaiQ42174255
Mary E WlodekQ61162846
P2093author name stringC L Masters
B C Fam
S Andrikopoulos
J Proietto
G D Ciccotosto
B E Needham
P2860cites workAssociation between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: cross sectional population based studyQ36246792
Risk of dementia among persons with diabetes mellitus: a population-based cohort studyQ39441115
Magnesium and other nutrient deficiencies as possible causes of hypertension and low birthweightQ39572234
Diabetes mellitus and the risk of dementia: The Rotterdam Study.Q53231897
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
GlucoseQ37525
preproinsulinQ7240673
P304page(s)155-163
P577publication date2008-06-01
P1433published inJournal of PathologyQ400296
P1476titleIdentification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth
P478volume215

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cites work (P2860)
Q37390973APLP2 regulates the expression of MHC class I molecules on irradiated Ewing's sarcoma cells
Q57092702APP involvement in retinogenesis of mice
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Q93033050Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues
Q36005686All in the Family: How the APPs Regulate Neurogenesis
Q44935800Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels.
Q52575657Amyloid Precursor Protein Dimerisation Reduces Neurite Outgrowth.
Q36980803Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics
Q37427458Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors
Q38678160Amyloid precursor protein in pancreatic islets.
Q34141680Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina
Q41073036Amyloid-precursor Like Proteins APLP1 and APLP2 Are Dispensable for Normal Development of the Neonatal Respiratory Network
Q58561394Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex
Q36792589Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes.
Q53460407Combined deletions of amyloid precursor protein and amyloid precursor-like protein 2 reveal different effects on mouse brain metal homeostasis.
Q97570180Critical analysis of the use of β-site amyloid precursor protein-cleaving enzyme 1 inhibitors in the treatment of Alzheimer's disease
Q37375685Effects of glucose and insulin on secretion of amyloid-β by human adipose tissue cells
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Q40074092Insulin-like growth factor-1 (IGF-1)-induced processing of amyloid-beta precursor protein (APP) and APP-like protein 2 is mediated by different metalloproteinases
Q34510196Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets
Q92846358Multi-pathway Protective Effects of MicroRNAs on Human Chondrocytes in an In Vitro Model of Osteoarthritis
Q27001550Platelets and Alzheimer's disease: Potential of APP as a biomarker
Q42675934Quantitation and localization of intracellular redox active metals by X-ray fluorescence microscopy in cortical neurons derived from APP and APLP2 knockout tissue
Q36350742Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells
Q26750116The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain Injury
Q34533985Type 2 diabetes mellitus, dyslipidemia, and Alzheimer's disease

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