| P50 | author | Qinxi Guo | Q56903908 |
| | Hongmei Li | Q56903887 |
| P2093 | author name string | Hui Zheng | |
| | Zilai Wang | |
| | Mary Wiese | |
| P2860 | cites work | Trafficking of cell-surface amyloid beta-protein precursor. I. Secretion, endocytosis and recycling as detected by labeled monoclonal antibody | Q71354783 |
| | The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures | Q73107254 |
| | Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42 | Q77926799 |
| | Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice | Q22242267 |
| | Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc | Q24292400 |
| | Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease | Q24298553 |
| | Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor | Q24317632 |
| | Mutation of the mouse klotho gene leads to a syndrome resembling ageing | Q24328782 |
| | Suppression of aging in mice by the hormone Klotho | Q24650916 |
| | The amyloid precursor protein: beyond amyloid | Q24680465 |
| | Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP | Q26269904 |
| | Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis | Q26269915 |
| | Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth | Q28275333 |
| | alpha-Klotho as a regulator of calcium homeostasis | Q28306317 |
| | Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans | Q28475536 |
| | Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members | Q28504488 |
| | Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development | Q28506956 |
| | Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein | Q28513133 |
| | A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference | Q28565029 |
| | Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene | Q28586800 |
| | No hippocampal neuron or synaptic bouton loss in learning-impaired aged beta-amyloid precursor protein-null mice | Q28587148 |
| | Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor | Q28588379 |
| | Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2 | Q28589908 |
| | Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice | Q28590025 |
| | Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein | Q28592893 |
| | beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity | Q28593175 |
| | The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor | Q29618322 |
| | Functional interaction between acyl-CoA synthetase 4, lipooxygenases and cyclooxygenase-2 in the aggressive phenotype of breast cancer cells | Q33750005 |
| | Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo | Q33754509 |
| | An overview of APP processing enzymes and products | Q33927819 |
| | AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice. | Q34480004 |
| | A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function. | Q34685168 |
| | The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function. | Q34708261 |
| | Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. | Q35000938 |
| | Identification of NEEP21 as a β-Amyloid Precursor Protein-Interacting ProteinIn VivoThat Modulates Amyloidogenic ProcessingIn Vitro | Q35014671 |
| | APL-1, a Caenorhabditis elegans protein related to the human beta-amyloid precursor protein, is essential for viability | Q35629330 |
| | Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk? | Q35635088 |
| | Transthyretin sequesters amyloid beta protein and prevents amyloid formation | Q35700645 |
| | Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease | Q35754225 |
| | Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease | Q36482688 |
| | Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity | Q36497488 |
| | apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor | Q36741195 |
| | Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP). | Q36761978 |
| | What determines the molecular composition of abnormal protein aggregates in neurodegenerative disease? | Q37146578 |
| | The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains | Q37295364 |
| | Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells | Q37576797 |
| | Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila | Q37592533 |
| | Amyloid precursor protein regulates Cav1.2 L-type calcium channel levels and function to influence GABAergic short-term plasticity | Q39441413 |
| | Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling. | Q39883256 |
| | The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. | Q40106778 |
| | Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels | Q40416147 |
| | FAD mutant PS-1 gene-targeted mice: increased A beta 42 and A beta deposition without APP overproduction | Q40737559 |
| | Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain | Q42263336 |
| | Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. | Q42495065 |
| | The nuclear receptor gene nhr-25 plays multiple roles in the Caenorhabditis elegans heterochronic gene network to control the larva-to-adult transition | Q42580405 |
| | Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines | Q42735982 |
| | Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain. | Q44041873 |
| | Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain. | Q44822089 |
| | Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice | Q44878954 |
| | Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice. | Q44898890 |
| | A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing | Q45711202 |
| | Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene | Q45729428 |
| | Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease | Q46519969 |
| | Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin | Q46755710 |
| | Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. | Q46959740 |
| | Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/Mint. | Q47070740 |
| | Amyloid precursor protein is required for convergent-extension movements during Zebrafish development | Q47073538 |
| | Reduced synaptic vesicle density and active zone size in mice lacking amyloid precursor protein (APP) and APP-like protein 2. | Q47380653 |
| | Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin). | Q48124090 |
| | Hypersensitivity to seizures in beta-amyloid precursor protein deficient mice | Q48236519 |
| | Generation of conditional null alleles for APP and APLP2. | Q48316010 |
| | Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus | Q48349302 |
| | Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence | Q48915342 |
| | The amyloid cascade hypothesis | Q49075559 |
| | Generation of transgenic zebrafish expressing green fluorescent protein under control of zebrafish amyloid precursor protein gene regulatory elements. | Q50645716 |
| | Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning. | Q51971344 |
| | The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction. | Q52572881 |
| | Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway. | Q53303993 |
| P433 | issue | 1 | |
| P921 | main subject | pathophysiology | Q1135939 |
| P304 | page(s) | 78-89 | |
| P577 | publication date | 2011-07-19 | |
| P1433 | published in | Cell Research | Q1524018 |
| P1476 | title | APP physiological and pathophysiological functions: insights from animal models | |
| P478 | volume | 22 | |