scholarly article | Q13442814 |
P50 | author | Luciano D'Adamio | Q52350188 |
P2093 | author name string | Hui Zheng | |
Zilai Wang | |||
Alessia P M Barbagallo | |||
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Amino-terminal region of secreted form of amyloid precursor protein stimulates proliferation of neural stem cells | Q77773293 | ||
Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42 | Q77926799 | ||
Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter | Q24337889 | ||
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain | Q24536014 | ||
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP | Q26269904 | ||
Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis | Q26269915 | ||
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide | Q28131750 | ||
Mints as adaptors. Direct binding to neurexins and recruitment of munc18 | Q28141531 | ||
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60 | Q28205099 | ||
SynCAM, a synaptic adhesion molecule that drives synapse assembly | Q28219424 | ||
CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins | Q28288628 | ||
Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein | Q28513133 | ||
Neurobehavioral development, adult openfield exploration and swimming navigation learning in mice with a modified beta-amyloid precursor protein gene | Q28513269 | ||
Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene | Q28586800 | ||
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2 | Q28589908 | ||
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice | Q28590025 | ||
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity | Q28593175 | ||
Signal-dependent membrane protein trafficking in the endocytic pathway | Q29622948 | ||
Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo | Q33754509 | ||
JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65 | Q34761715 | ||
Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. | Q35000938 | ||
APL-1, a Caenorhabditis elegans protein related to the human beta-amyloid precursor protein, is essential for viability | Q35629330 | ||
Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk? | Q35635088 | ||
Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor | Q35638734 | ||
Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice. | Q36530142 | ||
Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role | Q36882015 | ||
The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains | Q37295364 | ||
Novel mediators of amyloid precursor protein signaling | Q39762318 | ||
Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling. | Q39883256 | ||
The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. | Q40106778 | ||
Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. | Q40714164 | ||
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. | Q42495065 | ||
Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain. | Q44041873 | ||
Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1. | Q44534322 | ||
Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain. | Q44822089 | ||
Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor. | Q48492125 | ||
Alzheimer amyloid protein precursor enhances proliferation of neural stem cells from fetal rat brain | Q72903742 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 8717-8721 | |
P577 | publication date | 2011-01-25 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function | |
P478 | volume | 286 |
Q33661653 | A new molecular explanation for age-related neurodegeneration: the Tyr682 residue of amyloid precursor protein |
Q28551424 | APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone |
Q39251175 | APP Protein Family Signaling at the Synapse: Insights from Intracellular APP-Binding Proteins |
Q36585916 | APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses |
Q36347215 | APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation. |
Q28543167 | APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functions |
Q35870089 | APP is phosphorylated by TrkA and regulates NGF/TrkA signaling |
Q37902514 | APP physiological and pathophysiological functions: insights from animal models. |
Q41045804 | Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration |
Q30531725 | Amyloid precursor protein (APP) regulates synaptic structure and function |
Q26769909 | Amyloid precursor protein and amyloid precursor-like protein 2 in cancer |
Q37869935 | Biology and pathophysiology of the amyloid precursor protein |
Q34255981 | Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. |
Q27316665 | FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation |
Q37935600 | Functions of the APP gene family in the nervous system: insights from mouse models |
Q34251023 | Knockdown of amyloid precursor protein in zebrafish causes defects in motor axon outgrowth |
Q34288710 | Neddylation dysfunction in Alzheimer's disease |
Q37408544 | Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's Disease |
Q39209681 | Not just amyloid: physiological functions of the amyloid precursor protein family |
Q89544702 | Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation |
Q37987144 | Physiological functions of APP family proteins |
Q38109402 | Redundancy and divergence in the amyloid precursor protein family |
Q27687528 | Structural aspects and physiological consequences of APP/APLP trans-dimerization |
Q40874327 | The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior. |
Q34708261 | The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function. |
Q27026919 | The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes |
Q98386132 | TrkB receptor cleavage by delta-secretase abolishes its phosphorylation of APP, aggravating Alzheimer's disease pathologies |
Q34854001 | Turnover of amyloid precursor protein family members determines their nuclear signaling capability |
Q36405899 | Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance |
Q35297339 | Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction. |
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