| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2011PLoSO...618006B |
| P356 | DOI | 10.1371/JOURNAL.PONE.0018006 |
| P932 | PMC publication ID | 3062548 |
| P698 | PubMed publication ID | 21445342 |
| P5875 | ResearchGate publication ID | 50892403 |
| P50 | author | Luciano D'Adamio | Q52350188 |
| P2093 | author name string | Hui Zheng | |
| Zilai Wang | |||
| Alessia P M Barbagallo | |||
| P2860 | cites work | Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc | Q24292400 |
| The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production | Q24309767 | ||
| Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter | Q24337889 | ||
| The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling | Q24531382 | ||
| Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism? | Q24684898 | ||
| Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis | Q26269915 | ||
| Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide | Q28131750 | ||
| Tip60 acetylates six lysines of a specific class in core histones in vitro | Q28140015 | ||
| Mints as adaptors. Direct binding to neurexins and recruitment of munc18 | Q28141531 | ||
| Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription | Q28201680 | ||
| SynCAM, a synaptic adhesion molecule that drives synapse assembly | Q28219424 | ||
| Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1 | Q28236674 | ||
| CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins | Q28288628 | ||
| Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice | Q28505777 | ||
| Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1 | Q28506045 | ||
| Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein | Q28513133 | ||
| Defective neurite extension is caused by a mutation in amyloid beta/A4 (A beta) protein precursor found in familial Alzheimer's disease | Q46440208 | ||
| Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin | Q46755710 | ||
| Hypersensitivity to seizures in beta-amyloid precursor protein deficient mice | Q48236519 | ||
| Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis | Q48858833 | ||
| Similar levels of long-term potentiation in amyloid precursor protein -null and wild-type mice in the CA1 region of picrotoxin treated slices. | Q53236126 | ||
| Neurobehavioral development, adult openfield exploration and swimming navigation learning in mice with a modified beta-amyloid precursor protein gene | Q28513269 | ||
| Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene | Q28586800 | ||
| Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein | Q28587017 | ||
| No hippocampal neuron or synaptic bouton loss in learning-impaired aged beta-amyloid precursor protein-null mice | Q28587148 | ||
| Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2 | Q28589908 | ||
| Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice | Q28590025 | ||
| Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein | Q28592893 | ||
| beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity | Q28593175 | ||
| Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP. | Q33267310 | ||
| Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo | Q33754509 | ||
| The presenilins in Alzheimer's disease--proteolysis holds the key. | Q33763282 | ||
| The genetics and molecular pathology of Alzheimer's disease: roles of amyloid and the presenilins | Q34079605 | ||
| The value of transgenic models for the study of neurodegenerative diseases | Q34148237 | ||
| A portrait of Alzheimer secretases--new features and familiar faces | Q34345559 | ||
| Gamma-secretase: never more enigmatic | Q34553814 | ||
| gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in? | Q34609917 | ||
| A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function. | Q34685168 | ||
| JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65 | Q34761715 | ||
| Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. | Q35000938 | ||
| Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex | Q35105866 | ||
| Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk? | Q35635088 | ||
| Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases | Q35934211 | ||
| Has the amyloid cascade hypothesis for Alzheimer's disease been proved? | Q36393771 | ||
| The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein | Q36788339 | ||
| The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains | Q37295364 | ||
| Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells | Q37576797 | ||
| Novel mediators of amyloid precursor protein signaling | Q39762318 | ||
| Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling. | Q39883256 | ||
| The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. | Q40106778 | ||
| A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. | Q40660368 | ||
| Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. | Q42495065 | ||
| Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid | Q43715880 | ||
| Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain. | Q44041873 | ||
| Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. | Q44532915 | ||
| Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1. | Q44534322 | ||
| Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1. | Q44548877 | ||
| Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain. | Q44822089 | ||
| FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein. | Q46004266 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e18006 | |
| P577 | publication date | 2011-03-22 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function | |
| P478 | volume | 6 |
| Q33661653 | A new molecular explanation for age-related neurodegeneration: the Tyr682 residue of amyloid precursor protein |
| Q36585916 | APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses |
| Q28543167 | APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functions |
| Q37902514 | APP physiological and pathophysiological functions: insights from animal models. |
| Q41045804 | Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration |
| Q34603033 | An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss |
| Q24336083 | FKBP12 regulates the localization and processing of amyloid precursor protein in human cell lines |
| Q34251023 | Knockdown of amyloid precursor protein in zebrafish causes defects in motor axon outgrowth |
| Q39209681 | Not just amyloid: physiological functions of the amyloid precursor protein family |
| Q33676177 | Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells |
| Q37987144 | Physiological functions of APP family proteins |
| Q39319453 | Protein Phosphorylation is a Key Mechanism in Alzheimer's Disease |
| Q38109402 | Redundancy and divergence in the amyloid precursor protein family |
| Q38923425 | The ITM2B (BRI2) gene is a target of BCL6 repression: Implications for lymphomas and neurodegenerative diseases |
| Q35796886 | Understanding cancer stem cell heterogeneity and plasticity. |
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