Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling.

scientific article

Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3233/JAD-2009-0970
P8608Fatcat IDrelease_d4g6ize27bha7jqwv6lstl3bny
P698PubMed publication ID19221419

P50authorDawang ZhouQ37382920
Luciano D'AdamioQ52350188
Nicola ZambranoQ55860340
Tommaso RussoQ56855055
P2093author name stringLuciano D'Adamio
Nicola Zambrano
Tommaso Russo
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)301-307
P577publication date2009-01-01
P1433published inJournal of Alzheimer's DiseaseQ6294755
P1476titlePhosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling
P478volume16

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cites work (P2860)
Q33661653A new molecular explanation for age-related neurodegeneration: the Tyr682 residue of amyloid precursor protein
Q35997626A persistent stress response to impeded axonal transport leads to accumulation of amyloid-β in the endoplasmic reticulum, and is a probable cause of sporadic Alzheimer's disease
Q34685168A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function.
Q28543167APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functions
Q35870089APP is phosphorylated by TrkA and regulates NGF/TrkA signaling
Q37902514APP physiological and pathophysiological functions: insights from animal models.
Q41045804Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration
Q37563893Amyloid beta a4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as new binding proteins in the human brain
Q34603033An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss
Q38002193Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems
Q37295364The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains
Q34708261The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function.
Q33754509Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo
Q36405899Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance
Q30494084Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease
Q35006203Visualization and quantification of APP intracellular domain-mediated nuclear signaling by bimolecular fluorescence complementation
Q35297339Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction.
Q45893010¹H, ¹³C, and ¹⁵N chemical shift assignments of the phosphotyrosine binding domain 2 (PTB2) of human FE65.

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