| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1998PNAS...9512683M |
| P356 | DOI | 10.1073/PNAS.95.21.12683 |
| P932 | PMC publication ID | 22891 |
| P698 | PubMed publication ID | 9770546 |
| P5875 | ResearchGate publication ID | 13514736 |
| P50 | author | Stéphane Paul | Q60318264 |
| P2093 | author name string | S Little | |
| C Mathis | |||
| J Clemens | |||
| A Ungerer | |||
| H Meziane | |||
| J C Dodart | |||
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| Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain. | Q41098330 | ||
| Individual isoforms of the amyloid beta precursor protein demonstrate differential adhesive potentials to constituents of the extracellular matrix | Q41099300 | ||
| Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein. | Q41240734 | ||
| A direct role for protein kinase C and the transcription factor Jun/AP-1 in the regulation of the Alzheimer's beta-amyloid precursor protein gene | Q41447789 | ||
| Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury | Q41451125 | ||
| Historical review of research on protein kinase C in learning and memory | Q41471721 | ||
| Recognition memory in rats--II. Neuroanatomical substrates | Q41712058 | ||
| Cleavage of amyloid beta peptide during constitutive processing of its precursor | Q41852594 | ||
| Cholinesterase inhibitors increase secretion of APPs in rat brain cortex | Q42276951 | ||
| Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism | Q42984978 | ||
| The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II. | Q43466747 | ||
| Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor | Q46359315 | ||
| Defective neurite extension is caused by a mutation in amyloid beta/A4 (A beta) protein precursor found in familial Alzheimer's disease | Q46440208 | ||
| Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury | Q48092228 | ||
| Behavioral dissociation of anterodorsal and posteroventral hippocampus by subseizure stimulation in mice | Q48100419 | ||
| Increase in extracellular NCAM and amyloid precursor protein following induction of long-term potentiation in the dentate gyrus of anaesthetized rats | Q48157101 | ||
| Involvement of amyloid precursor protein in memory formation in the rat: an indirect antibody approach | Q48331232 | ||
| Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein | Q48342880 | ||
| Effects of post-trial hippocampal stimulation on time-dependent improvement of performance in mice | Q48515063 | ||
| Synaptic beta-amyloid precursor proteins increase with learning capacity in rats | Q48631513 | ||
| The amino-terminal region of amyloid precursor protein is responsible for neurite outgrowth in rat neocortical explant culture | Q48659259 | ||
| Secreted form of beta-amyloid precursor protein shifts the frequency dependency for induction of LTD, and enhances LTP in hippocampal slices | Q48659729 | ||
| Pharmacological modulation of Alzheimer's beta-amyloid precursor protein levels in the CSF of rats with forebrain cholinergic system lesions | Q48696243 | ||
| Time-dependent sequential increases in [14C]2-deoxyglucose uptake in subcortical and cortical structures during memory consolidation of an operant training in mice. | Q48697587 | ||
| Scopolamine-induced deficits in a two-trial object recognition task in mice | Q48761222 | ||
| The neurosteroid pregnenolone sulfate blocks deficits induced by a competitive NMDA antagonist in active avoidance and lever-press learning tasks in mice | Q48783330 | ||
| Intraventricular infusions of antibodies to amyloid-beta-protein precursor impair the acquisition of a passive avoidance response in the rat. | Q48932605 | ||
| The neurosteroid pregnenolone sulfate reduces learning deficits induced by scopolamine and has promnestic effects in mice performing an appetitive learning task. | Q52046889 | ||
| Spatial learning deficit in mice expressing human 751-amino acid beta-amyloid precursor protein. | Q52198981 | ||
| Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins | Q53200405 | ||
| Opposing regulation of amyloid precursor protein by ionotropic and metabotropic glutamate receptors | Q63241456 | ||
| Regulated secretion of beta-amyloid precursor protein in rat brain | Q71511604 | ||
| Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells | Q71971007 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 12683-12688 | |
| P577 | publication date | 1998-10-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice | |
| P478 | volume | 95 |
| Q37081815 | A TAG on to the neurogenic functions of APP |
| Q40841974 | A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model |
| Q24312803 | A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein |
| Q36078010 | A role for the beta-amyloid precursor protein in memory? |
| Q34685168 | A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function. |
| Q53366645 | ADAM10 gene expression in the blood cells of Alzheimer's disease patients and mild cognitive impairment subjects. |
| Q39672952 | ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons |
| Q35036124 | AMPA receptor activation promotes non-amyloidogenic amyloid precursor protein processing and suppresses neuronal amyloid-β production |
| Q39251175 | APP Protein Family Signaling at the Synapse: Insights from Intracellular APP-Binding Proteins |
| Q34551487 | APP as a Protective Factor in Acute Neuronal Insults |
| Q49144347 | APP is required during an early phase of memory formation |
| Q35019451 | Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease. |
| Q48444707 | Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity. |
| Q42519345 | Age-dependent differential regulation of genes encoding APP and alpha-synuclein in hippocampal synaptic plasticity |
| Q43975380 | Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour. |
| Q35069720 | Alzheimer vaccine: amyloid-beta on trial. |
| Q48239128 | Alzheimer's disease proteins in cerebellar and hippocampal synapses during postnatal development and aging of the rat. |
| Q92603838 | Alzheimer's disease: pathogenesis, diagnostics, and therapeutics |
| Q36994590 | Alzheimer's disease: the lipid connection |
| Q35775000 | Amyloid at the cutting edge: activation of alpha-secretase prevents amyloidogenesis in an Alzheimer disease mouse model |
| Q43155401 | Amyloid beta mediates memory formation |
| Q37860317 | Amyloid precursor protein processing and Alzheimer's disease |
| Q29617429 | Amyloid precursor protein trafficking, processing, and function |
| Q48773075 | Amyloid precursor protein: from synaptic plasticity to Alzheimer's disease |
| Q27012950 | Amyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's disease |
| Q36966660 | Amyloid-β peptide: Dr. Jekyll or Mr. Hyde? |
| Q33927819 | An overview of APP processing enzymes and products |
| Q48356560 | Analysis of differential gene expression supports a role for amyloid precursor protein and a protein kinase C substrate (MARCKS) in long-term memory |
| Q34126136 | Animal models of Alzheimer's disease and evaluation of anti-dementia drugs |
| Q33971304 | Approaches to discovery and characterization of inhibitors of amyloid beta-peptide polymerization |
| Q47641650 | Arachidonic or Docosahexaenoic Acid Diet Prevents Memory Impairment in Tg2576 Mice. |
| Q36070820 | Association of Choline Acetyltransferase Gene Polymorphisms (SNPs rs868750G/A, rs1880676G/A, rs2177369G/A and rs3810950G/A) with Alzheimer's Disease Risk: A Meta-Analysis |
| Q27022080 | Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells |
| Q42079055 | Bacopa monniera Attenuates Scopolamine-Induced Impairment of Spatial Memory in Mice |
| Q90083096 | Beyond the Ligand: Extracellular and Transcellular G Protein-Coupled Receptor Complexes in Physiology and Pharmacology |
| Q42728923 | Bioinformatics identification of modules of transcription factor binding sites in Alzheimer's disease-related genes by in silico promoter analysis and microarrays |
| Q37869935 | Biology and pathophysiology of the amyloid precursor protein |
| Q34102952 | Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: an update |
| Q34988301 | Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease |
| Q88488990 | Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology |
| Q34391211 | Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody |
| Q35734048 | Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation |
| Q44292668 | Combined treatment with galanthaminium bromide, a new cholinesterase inhibitor, and RS 67333, a partial agonist of 5-HT4 receptors, enhances place and object recognition in young adult and old rats. |
| Q42218764 | Comparable dimerization found in wildtype and familial Alzheimer's disease amyloid precursor protein mutants. |
| Q42111601 | Complexing Aβ prevents the cellular anomalies induced by the Peptide alone |
| Q39287009 | Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines |
| Q34222721 | Current and emerging drug treatment options for Alzheimer's disease: a systematic review. |
| Q45797934 | Cyclic adenosine monophosphate as an endogenous modulator of the amyloid-β precursor protein metabolism. |
| Q35537641 | Defective response inhibition and collicular noradrenaline enrichment in mice with duplicated retinotopic map in the superior colliculus. |
| Q33793579 | Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo |
| Q33939218 | Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and γ-secretase |
| Q36329164 | Development of beta-amyloid-induced neurodegeneration in Alzheimer's disease and novel neuroprotective strategies. |
| Q37665855 | Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimer's disease |
| Q33406031 | Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice |
| Q45266419 | Difluorophenylglycinols as new modulators of proteolytic processing of amyloid precursor proteins |
| Q37572741 | Disease-modifying approach to the treatment of Alzheimer's disease: from alpha-secretase activators to gamma-secretase inhibitors and modulators. |
| Q54234721 | Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition. |
| Q24816713 | Does cholesterol act as a protector of cholinergic projections in Alzheimer's disease? |
| Q50507076 | Ectodomain shedding of nectin-1 regulates the maintenance of dendritic spine density. |
| Q42810444 | Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs. |
| Q33993507 | Effect size of reference memory deficits in the Morris water maze in Tg2576 mice |
| Q48021355 | Enhanced neuronal plasticity and elevated endogenous sAPPα levels in mice over-expressing MMP9. |
| Q33766789 | Environmental experience modulates ischemia-induced amyloidogenesis and enhances functional recovery |
| Q48293961 | Estrogen, beta-amyloid metabolism/trafficking, and Alzheimer's disease |
| Q46240526 | Etazolate, a neuroprotective drug linking GABA(A) receptor pharmacology to amyloid precursor protein processing |
| Q33881587 | Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness |
| Q47965152 | Functional and morphological alterations in compound transgenic mice overexpressing Cu/Zn superoxide dismutase and amyloid precursor protein [correction]. |
| Q37965817 | Functions of Aβ, sAPPα and sAPPβ : similarities and differences |
| Q36052527 | Genetic and pharmacological approaches to evaluate the interaction between the cannabinoid and cholinergic systems in cognitive processes |
| Q91904075 | Glutamate Receptor Trafficking and Protein Synthesis Mediate the Facilitation of LTP by Secreted Amyloid Precursor Protein-Alpha |
| Q91635058 | Hebbian and Homeostatic Synaptic Plasticity-Do Alterations of One Reflect Enhancement of the Other? |
| Q37961730 | Identification and biology of α-secretase. |
| Q52009792 | Identification of a single nucleotide polymorphism in the choline acetyltransferase gene associated with Alzheimer's disease. |
| Q47844206 | Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8. |
| Q38608328 | Impaired theta-gamma coupling in APP-deficient mice. |
| Q39431937 | Implications of peptide assemblies in amyloid diseases |
| Q40049769 | Interleukin-1 beta up-regulates TACE to enhance alpha-cleavage of APP in neurons: resulting decrease in Abeta production |
| Q52656382 | Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development. |
| Q35768842 | Involvement of beta-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity. |
| Q90356091 | Is the p3 Peptide (Aβ17-40, Aβ17-42) Relevant to the Pathology of Alzheimer's Disease?1 |
| Q26765824 | Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease |
| Q37732115 | L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline. |
| Q44456132 | Lack of association between a single nucleotide polymorphism within the choline acetyltransferase gene and patients with Alzheimer's disease |
| Q50094019 | Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease |
| Q35897595 | Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10. |
| Q34347798 | Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization |
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| Q91404770 | New Alzheimer's disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers |
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