| scholarly article | Q13442814 |
| P2093 | author name string | Fred S Wouters | |
| Matthias Gralle | |||
| Michelle Gralle Botelho | |||
| P2860 | cites work | Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein | Q22241520 |
| Homo- and heterodimerization of APP family members promotes intercellular adhesion | Q24337232 | ||
| Reaching out for signals: filopodia sense EGF and respond by directed retrograde transport of activated receptors | Q24678987 | ||
| Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein | Q27617913 | ||
| Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein | Q27861056 | ||
| Alzheimer's disease: genes, proteins, and therapy | Q28131806 | ||
| Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network | Q28143129 | ||
| Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease | Q28241772 | ||
| Evidence that production and release of amyloid beta-protein involves the endocytic pathway | Q28244336 | ||
| ADAM-10 over-expression increases cortical synaptogenesis | Q28280531 | ||
| APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy | Q28288090 | ||
| Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members | Q28504488 | ||
| A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference | Q28565029 | ||
| A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis | Q28587599 | ||
| Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2 | Q28589908 | ||
| Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells | Q29547331 | ||
| The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor | Q29618322 | ||
| Imaging molecular interactions in cells by dynamic and static fluorescence anisotropy (rFLIM and emFRET). | Q33193242 | ||
| The beta-amyloid precursor protein controls a store-operated Ca2+ entry in cortical neurons | Q33207345 | ||
| GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. | Q33276402 | ||
| Synaptic targeting by Alzheimer's-related amyloid beta oligomers. | Q33288786 | ||
| Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants | Q33317424 | ||
| Superresolution by localization of quantum dots using blinking statistics | Q33461367 | ||
| Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-beta plaque deposition | Q33756388 | ||
| Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: an update | Q34102952 | ||
| The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain | Q34340080 | ||
| Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction. | Q34562025 | ||
| A dark yellow fluorescent protein (YFP)-based Resonance Energy-Accepting Chromoprotein (REACh) for Förster resonance energy transfer with GFP. | Q34572939 | ||
| Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss | Q35918370 | ||
| Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals | Q36382397 | ||
| Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice. | Q36530142 | ||
| Imaging molecular interactions in living cells by FRET microscopy | Q36584035 | ||
| Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. | Q36740945 | ||
| Structure and functions of the human amyloid precursor protein: the whole is more than the sum of its parts | Q36788739 | ||
| Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein | Q36935627 | ||
| A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis | Q37083598 | ||
| A closer look at alpha-secretase | Q37130663 | ||
| Secreted form of amyloid beta/A4 protein precursor (APP) binds to two distinct APP binding sites on rat B103 neuron-like cells through two different domains, but only one site is involved in neuritotropic activity. | Q39305257 | ||
| Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons. | Q40003065 | ||
| Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP. | Q40027243 | ||
| Biotin-ligand complexes with streptavidin quantum dots for in vivo cell labeling of membrane receptors | Q40181143 | ||
| Solution studies and structural model of the extracellular domain of the human amyloid precursor protein | Q40219967 | ||
| The receptor-bound N-terminal ectodomain of the amyloid precursor protein is associated with membrane rafts. | Q40674513 | ||
| Antibody-regulated neurotoxic function of cell-surface beta-amyloid precursor protein | Q40836196 | ||
| A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model | Q40841974 | ||
| Binding and selective detection of the secretory N-terminal domain of the alzheimer amyloid precursor protein on cell surfaces | Q40971910 | ||
| The expression of amyloid beta protein precursor protects nerve cells from beta-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix | Q41509726 | ||
| A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis | Q41737049 | ||
| Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs | Q41822677 | ||
| Fluorescence lifetime heterogeneity resolution in the frequency domain by lifetime moments analysis | Q42183780 | ||
| Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain | Q42263336 | ||
| Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. | Q42495065 | ||
| Beta-amyloid precursor protein is detectable on monocytes and is increased in Alzheimer's disease | Q42615013 | ||
| The secreted form of the Alzheimer's beta-amyloid precursor protein stimulates a membrane-associated guanylate cyclase | Q42822424 | ||
| Secreted Abeta does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein | Q43636557 | ||
| Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease. | Q43662767 | ||
| The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization. | Q44493507 | ||
| Specific labeling of cell surface proteins with chemically diverse compounds | Q44986275 | ||
| Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis. | Q45041133 | ||
| Amyloid precursor protein of Alzheimer's disease: evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures | Q48228409 | ||
| Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein | Q48342880 | ||
| Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation | Q48628855 | ||
| Alzheimer's beta-amyloid precursor protein is expressed on the surface of immediately ex vivo brain cells: a flow cytometric study | Q48875777 | ||
| Amyloid precursor protein family-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway. | Q52545476 | ||
| Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. | Q53188216 | ||
| Decreased α-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's diseas | Q53200551 | ||
| Solution Conformation and Heparin-induced Dimerization of the Full-length Extracellular Domain of the Human Amyloid Precursor Protein | Q57361076 | ||
| Covalent labeling of cell-surface proteins for in-vivo FRET studies | Q63363677 | ||
| Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner | Q72632596 | ||
| The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis | Q72787226 | ||
| Levels of alpha- and beta-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients | Q73398033 | ||
| Solution conformations of a peptide containing the cytoplasmic domain sequence of the beta amyloid precursor protein | Q73456204 | ||
| Three-dimensional structure of an independently folded extracellular domain of human amyloid-beta precursor protein | Q80380254 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 22 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 15016-15025 | |
| P577 | publication date | 2009-03-31 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers | |
| P478 | volume | 284 |
| Q47728000 | ADAM10 as a therapeutic target for brain diseases: from developmental disorders to Alzheimer's disease |
| Q33926960 | ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function |
| Q36840033 | APP Receptor? To Be or Not To Be. |
| Q42563807 | APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms |
| Q35787737 | Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-α: implications for autism. |
| Q33572654 | Aberrant amyloid precursor protein (APP) processing in hereditary forms of Alzheimer disease caused by APP familial Alzheimer disease mutations can be rescued by mutations in the APP GxxxG motif |
| Q36005686 | All in the Family: How the APPs Regulate Neurogenesis |
| Q34328562 | Altering APP proteolysis: increasing sAPPalpha production by targeting dimerization of the APP ectodomain |
| Q36535484 | Alzheimer disease and platelets: how's that relevant |
| Q39189107 | Amyloid Precursor Protein family as unconventional Go-coupled receptors and the control of neuronal motility |
| Q41547929 | Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta. |
| Q33646390 | Amyloid precursor protein mediates a tyrosine kinase-dependent activation response in endothelial cells |
| Q27012950 | Amyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's disease |
| Q41325973 | Amyloid-β Protein Precursor Cleavage Products in Postmortem Ventricular Cerebrospinal Fluid of Alzheimer's Disease Patients |
| Q34156758 | BACE1 (β-secretase) inhibitors for the treatment of Alzheimer's disease |
| Q93258140 | Behavioral and Cognitive Improvement Induced by Novel Imidazoline I2 Receptor Ligands in Female SAMP8 Mice |
| Q90083096 | Beyond the Ligand: Extracellular and Transcellular G Protein-Coupled Receptor Complexes in Physiology and Pharmacology |
| Q38263685 | Brain-Derived Neurotrophic Factor in Alzheimer's Disease: Risk, Mechanisms, and Therapy |
| Q42268906 | Calcium-Sensing Receptor Antagonist NPS 2143 Restores Amyloid Precursor Protein Physiological Non-Amyloidogenic Processing in Aβ-Exposed Adult Human Astrocytes. |
| Q38781934 | Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease |
| Q90621944 | Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice |
| Q42218764 | Comparable dimerization found in wildtype and familial Alzheimer's disease amyloid precursor protein mutants. |
| Q42578574 | Competition between homodimerization and cholesterol binding to the C99 domain of the amyloid precursor protein |
| Q27670602 | Crystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose Octasulfate |
| Q27674231 | Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization |
| Q33793579 | Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo |
| Q38194193 | Demystifying heparan sulfate-protein interactions. |
| Q41073215 | Developing BACE-1 inhibitors for FXS. |
| Q42166961 | Effects of oxidative stress on amyloid precursor protein processing in rat and human platelets |
| Q39032252 | Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium |
| Q33796184 | Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein |
| Q35679568 | Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway. |
| Q36207429 | Homodimerization of amyloid precursor protein at the plasma membrane: a homoFRET study by time-resolved fluorescence anisotropy imaging |
| Q50574806 | Human umbilical cord blood-derived monocytes improve cognitive deficits and reduce amyloid-β pathology in PSAPP mice. |
| Q37961730 | Identification and biology of α-secretase. |
| Q26999922 | Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease |
| Q39691943 | L-3-n-butylphthalide improves cognitive impairment and reduces amyloid-beta in a transgenic model of Alzheimer's disease |
| Q96303981 | L-histidine and L-carnosine exert anti-brain aging effects in D-galactose-induced aged neuronal cells |
| Q34347798 | Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization |
| Q40364440 | Modulation of BAG3 Expression and Proteasomal Activity by sAPPα Does Not Require Membrane-Tethered Holo-APP. |
| Q34221138 | Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease |
| Q99711299 | New Insights Into Blood-Brain Barrier Maintenance: The Homeostatic Role of β-Amyloid Precursor Protein in Cerebral Vasculature |
| Q34653599 | Non-selective calcium channel blocker bepridil decreases secondary pathology in mice after photothrombotic cortical lesion |
| Q39209681 | Not just amyloid: physiological functions of the amyloid precursor protein family |
| Q58695146 | Possible Clues for Brain Energy Translation via Endolysosomal Trafficking of APP-CTFs in Alzheimer's Disease |
| Q93017651 | Post-Translational Modification-Dependent Activity of Matrix Metalloproteinases |
| Q34107567 | Probing cellular events, one quantum dot at a time |
| Q37850214 | Quantum dots in cell biology |
| Q38002193 | Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems |
| Q36350742 | Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells |
| Q38929253 | Restoring Soluble Amyloid Precursor Protein α Functions as a Potential Treatment for Alzheimer's Disease. |
| Q28479242 | Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons |
| Q39135552 | Role of APP Interactions with Heterotrimeric G Proteins: Physiological Functions and Pathological Consequences |
| Q28072008 | Role of Drosophila Amyloid Precursor Protein in Memory Formation |
| Q37956562 | Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging |
| Q33988005 | Secreted human amyloid precursor protein binds semaphorin 3a and prevents semaphorin-induced growth cone collapse. |
| Q47688609 | Soluble Amyloid Precursor Protein Alpha Interacts with alpha3-Na, K-ATPAse to Induce Axonal Outgrowth but Not Neuroprotection: Evidence for Distinct Mechanisms Underlying these Properties |
| Q36218830 | Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3β signaling pathway |
| Q36462366 | Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation |
| Q37727192 | Structural and functional alterations in amyloid-β precursor protein induced by amyloid-β peptides |
| Q24600927 | Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein |
| Q39755143 | The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques. |
| Q27667862 | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization |
| Q26750116 | The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain Injury |
| Q39242629 | The Role of ADAM10 in Alzheimer's Disease |
| Q41546713 | The full-length form of the Drosophila amyloid precursor protein is involved in memory formation. |
| Q43478510 | The neuroprotective activity of the amyloid precursor protein against traumatic brain injury is mediated via the heparin binding site in residues 96-110. |
| Q39414505 | The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system |
| Q38038399 | What's hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders |
| Q34049978 | Withanolide A and asiatic acid modulate multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance |
| Q48558580 | sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury |
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