scholarly article | Q13442814 |
P50 | author | Dennis J. Selkoe | Q1189220 |
Tracy L Young-Pearse | Q64009890 | ||
P2093 | author name string | Jilin Bai | |
Joseph J LoTurco | |||
Rui Chang | |||
Jessica B Zheng | |||
P2860 | cites work | Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein | Q22241520 |
The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo | Q24306930 | ||
Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage | Q24312009 | ||
Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor | Q24317632 | ||
Homo- and heterodimerization of APP family members promotes intercellular adhesion | Q24337232 | ||
The amyloid-beta precursor protein: integrating structure with biological function | Q24540102 | ||
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein | Q27617913 | ||
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics | Q27860914 | ||
Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains. | Q27863303 | ||
Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1 | Q28142896 | ||
Interactions between Alzheimer's disease and cerebral ischemia--focus on inflammation | Q28174277 | ||
The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments | Q28182185 | ||
Reelin and brain development | Q28207865 | ||
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid | Q28207898 | ||
Aberrant splicing of a mouse disabled homolog, mdab1, in the scrambler mouse | Q28248620 | ||
DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing | Q28261752 | ||
Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein | Q28290411 | ||
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members | Q28504488 | ||
RNAi reveals doublecortin is required for radial migration in rat neocortex | Q28567912 | ||
The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity | Q28587197 | ||
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice | Q28590025 | ||
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity | Q28593175 | ||
Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease | Q33725164 | ||
Binding partners of Alzheimer's disease proteins: are they physiologically relevant? | Q33946848 | ||
The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids | Q33958834 | ||
A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease | Q34955569 | ||
A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein | Q35021238 | ||
The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement | Q36293844 | ||
The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins | Q36626425 | ||
beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin | Q36636403 | ||
Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP). | Q36761978 | ||
The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein | Q36788339 | ||
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth | Q38309410 | ||
The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. | Q40106778 | ||
Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11alpha. | Q40320662 | ||
Notch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression | Q40636877 | ||
Amyloid precursor protein potentiates the neurotrophic activity of NGF. | Q41060779 | ||
Expression, Purification, and Neurotrophic Activity of Amyloid Precursor Protein-Secreted Forms Produced by Yeast | Q41313255 | ||
Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives | Q41630805 | ||
Trophic effect of beta-amyloid precursor protein on cerebral cortical neurons in culture | Q41656266 | ||
The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion | Q41760569 | ||
Development of the endopiriform nucleus and the claustrum in the rat brain | Q42468830 | ||
Cell migration in the rat embryonic neocortex | Q42471382 | ||
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. | Q42495065 | ||
Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation. | Q46535530 | ||
Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein li | Q47357147 | ||
Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation | Q47880848 | ||
Intraneuronal compartments of the amyloid precursor protein. | Q48258074 | ||
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth | Q48458288 | ||
Impaired neuronal positioning and dendritogenesis in the neocortex after cell-autonomous Dab1 suppression. | Q48655898 | ||
The amino-terminal region of amyloid precursor protein is responsible for neurite outgrowth in rat neocortical explant culture | Q48659259 | ||
Efficient in utero gene transfer system to the developing mouse brain using electroporation: visualization of neuronal migration in the developing cortex | Q48919857 | ||
Characterization of high affinity binding between laminin and Alzheimer's disease amyloid precursor proteins. | Q53179680 | ||
An interaction between basement membrane and Alzheimer amyloid precursor proteins suggests a role in the pathogenesis of Alzheimer's disease. | Q53204203 | ||
APP-collagen interaction is mediated by a heparin bridge mechanism. | Q53293826 | ||
Reelin binds alpha3beta1 integrin and inhibits neuronal migration. | Q55034150 | ||
Low-density lipoprotein receptor-related protein levels and endocytic function are reduced by overexpression of the FE65 adaptor protein, FE65L1. | Q55473216 | ||
High affinity interactions between the Alzheimer's beta-amyloid precursor proteins and the basement membrane form of heparan sulfate proteoglycan | Q67992893 | ||
Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells | Q71971007 | ||
Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42 | Q77926799 | ||
P433 | issue | 52 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | RNA interference | Q201993 |
P304 | page(s) | 14459-14469 | |
P577 | publication date | 2007-12-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference | |
P478 | volume | 27 |
Q37081815 | A TAG on to the neurogenic functions of APP |
Q47951417 | A mobile APP for sharing contacts on your cell: An Editorial Highlight for 'The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system' on page 11. |
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Q34200883 | A tightly controlled conditional knockdown system using the Tol2 transposon-mediated technique. |
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Q35180666 | ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1 |
Q48138450 | APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding |
Q37162747 | APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease. |
Q42689739 | APP independent and dependent effects on neurite outgrowth are modulated by the receptor associated protein (RAP). |
Q57092702 | APP involvement in retinogenesis of mice |
Q37902514 | APP physiological and pathophysiological functions: insights from animal models. |
Q93033050 | Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues |
Q37418097 | Acute inactivation of the serine-threonine kinase Stk25 disrupts neuronal migration. |
Q36983553 | Addiction genetics and pleiotropic effects of common haplotypes that make polygenic contributions to vulnerability to substance dependence |
Q98174554 | Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles |
Q36005686 | All in the Family: How the APPs Regulate Neurogenesis |
Q59412136 | Alterations of functional circuitry in aging brain and the impact of mutated APP expression |
Q34421064 | Altered expression of Alzheimer's disease-related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy |
Q38749991 | Alternative Processing of the Amyloid Precursor Protein Family by Rhomboid Protease RHBDL4. |
Q26747569 | Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms |
Q84113248 | Alzheimer's disease |
Q44461865 | Alzheimer's disease: ageing-related or age-related? New hypotheses from an old debate |
Q92603838 | Alzheimer's disease: pathogenesis, diagnostics, and therapeutics |
Q47113449 | Amino-Terminal β-Amyloid Antibody Blocks β-Amyloid-Mediated Inhibition of the High-Affinity Choline Transporter CHT. |
Q35855501 | Amyloid Precursor Protein Translation Is Regulated by a 3'UTR Guanine Quadruplex |
Q39189107 | Amyloid Precursor Protein family as unconventional Go-coupled receptors and the control of neuronal motility |
Q30829734 | Amyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development. |
Q34777829 | Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin |
Q38767379 | Amyloid precursor like protein-1 promotes JNK-mediated cell migration in Drosophila |
Q36965723 | Amyloid precursor protein 96-110 and beta-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids |
Q37427458 | Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors |
Q36124650 | Amyloid precursor protein at node of Ranvier modulates nodal formation |
Q34731871 | Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance |
Q47073538 | Amyloid precursor protein is required for convergent-extension movements during Zebrafish development |
Q37860317 | Amyloid precursor protein processing and Alzheimer's disease |
Q29617429 | Amyloid precursor protein trafficking, processing, and function |
Q96640302 | Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish |
Q36928448 | Amyloid precursor proteins interact with the heterotrimeric G protein Go in the control of neuronal migration |
Q27012950 | Amyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's disease |
Q34969012 | Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer |
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Q37614648 | Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents. |
Q28658612 | Asynchronous evolutionary origins of Aβ and BACE1 |
Q30651711 | Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway |
Q34953710 | Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links |
Q41928807 | BECN1/Beclin 1 sorts cell-surface APP/amyloid β precursor protein for lysosomal degradation |
Q38787171 | Behavioral Resilience and Sensitivity to Locally Restricted Cortical Migration Deficits Induced by In Utero Knockdown of Disabled-1 in the Adult Rat. |
Q42735982 | Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines |
Q34480173 | Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development |
Q37869935 | Biology and pathophysiology of the amyloid precursor protein |
Q26738423 | Canonical and Non-canonical Reelin Signaling |
Q42371397 | Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants |
Q42218764 | Comparable dimerization found in wildtype and familial Alzheimer's disease amyloid precursor protein mutants. |
Q47441289 | Complexity and Selectivity of γ-Secretase Cleavage on Multiple Substrates: Consequences in Alzheimer's Disease and Cancer. |
Q38999340 | Current Perspective of Stem Cell Therapy in Neurodegenerative and Metabolic Diseases |
Q36634401 | DISC1 genetics, biology and psychiatric illness |
Q28302106 | DISC1-binding proteins in neural development, signalling and schizophrenia |
Q35893533 | Deficits in axonal transport in hippocampal-based circuitry and the visual pathway in APP knock-out animals witnessed by manganese enhanced MRI. |
Q34255981 | Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. |
Q38875417 | Differential regulation of the high-affinity choline transporter by wild-type and Swedish mutant amyloid precursor protein |
Q58562175 | Distal Dendritic Enrichment of HCN1 Channels in Hippocampal CA1 Is Promoted by Estrogen, but Does Not Require Reelin |
Q37405228 | Dosage of amyloid precursor protein affects axonal contact guidance in Down syndrome |
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Q42124529 | Downregulation of L1 perturbs neuronal migration and alters the expression of transcription factors in murine neocortex |
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Q39802765 | EFHC1 interacts with microtubules to regulate cell division and cortical development |
Q48605184 | Efficient gene transfer into neonatal mouse brain using electroporation |
Q48268002 | Embryonic mosaic deletion of APP results in displaced Reelin-expressing cells in the cerebral cortex |
Q64109078 | Emergence of synaptic and cognitive impairment in a mature-onset APP mouse model of Alzheimer’s disease |
Q34141836 | Emerging topics in Reelin function |
Q41210086 | Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory |
Q36488014 | Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease |
Q28505100 | Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex |
Q38892007 | Exosomes Secreted from HEK293-APP Swe/Ind Cells Impair the Hippocampal Neurogenesis |
Q37899107 | Extracellular matrix functions during neuronal migration and lamination in the mammalian central nervous system |
Q34413038 | Extracellular matrix: functions in the nervous system |
Q35660090 | FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness |
Q88954641 | Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes |
Q37965817 | Functions of Aβ, sAPPα and sAPPβ : similarities and differences |
Q37935600 | Functions of the APP gene family in the nervous system: insights from mouse models |
Q42744631 | Fyn kinase regulates the association between amyloid precursor protein and Dab1 by promoting their localization to detergent-resistant membranes |
Q37604848 | Generation of topically transgenic rats by in utero electroporation and in vivo bioluminescence screening. |
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Q54580271 | Going the wrong road: Fyn and targeting of amyloid precursor protein to lipid rafts. |
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