| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1040054870 |
| P356 | DOI | 10.1186/1749-8104-3-15 |
| P932 | PMC publication ID | 2442059 |
| P698 | PubMed publication ID | 18573216 |
| P5875 | ResearchGate publication ID | 5281615 |
| P50 | author | Dennis J. Selkoe | Q1189220 |
| Tracy L Young-Pearse | Q64009890 | ||
| P2093 | author name string | Rui Chang | |
| Cesar Marquez | |||
| Allen C Chen | |||
| P2860 | cites work | The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo | Q24306930 |
| Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor | Q24317632 | ||
| BACE (beta-secretase) modulates the processing of APLP2 in vivo | Q24336570 | ||
| Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling | Q24553489 | ||
| Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein | Q27617913 | ||
| Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription | Q28201680 | ||
| gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins | Q28207962 | ||
| Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1 | Q28236674 | ||
| The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation | Q28245707 | ||
| Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein | Q28290411 | ||
| A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference | Q28565029 | ||
| RNAi reveals doublecortin is required for radial migration in rat neocortex | Q28567912 | ||
| Alpha1beta1-integrin is an essential signal for neurite outgrowth induced by thrombospondin type 1 repeats of SCO-spondin | Q28571948 | ||
| The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity | Q28587197 | ||
| Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor | Q28588379 | ||
| Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice | Q28590025 | ||
| beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity | Q28593175 | ||
| Novel roles for integrins in the nervous system | Q33843150 | ||
| Binding partners of Alzheimer's disease proteins: are they physiologically relevant? | Q33946848 | ||
| Integrin function and regulation in development. | Q34075661 | ||
| Reelin, integrin and DAB1 interactions during embryonic cerebral cortical development | Q34392786 | ||
| Integrin alpha 8 beta 1 promotes attachment, cell spreading, and neurite outgrowth on fibronectin | Q34447949 | ||
| Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases | Q35934211 | ||
| The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement | Q36293844 | ||
| The multipolar stage and disruptions in neuronal migration | Q36483645 | ||
| Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components | Q36831631 | ||
| Presenilin: running with scissors in the membrane | Q36979995 | ||
| Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease | Q38306848 | ||
| A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching | Q39739662 | ||
| The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. | Q40106778 | ||
| Amyloid precursor protein potentiates the neurotrophic activity of NGF. | Q41060779 | ||
| Expression, Purification, and Neurotrophic Activity of Amyloid Precursor Protein-Secreted Forms Produced by Yeast | Q41313255 | ||
| Trophic effect of beta-amyloid precursor protein on cerebral cortical neurons in culture | Q41656266 | ||
| Cleavage of amyloid beta peptide during constitutive processing of its precursor | Q41852594 | ||
| Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. | Q42495065 | ||
| FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein. | Q46004266 | ||
| Polysialic acid limits septal neurite outgrowth on laminin | Q48254600 | ||
| The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth | Q48458288 | ||
| Immunohistochemical localization of beta-amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy | Q48511388 | ||
| Alzheimer's beta-amyloid precursor protein is expressed on the surface of immediately ex vivo brain cells: a flow cytometric study | Q48875777 | ||
| The amyloid precursor protein is concentrated in neuronal lysosomes in normal and Alzheimer disease subjects. | Q53300850 | ||
| Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells | Q71971007 | ||
| P921 | main subject | neurite | Q1534415 |
| P304 | page(s) | 15 | |
| P577 | publication date | 2008-06-23 | |
| P1433 | published in | Neural Development | Q15761981 |
| P1476 | title | Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. | |
| P478 | volume | 3 |
| Q35180666 | ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1 |
| Q36840033 | APP Receptor? To Be or Not To Be. |
| Q35052570 | APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP. |
| Q22251088 | APP binds DR6 to trigger axon pruning and neuron death via distinct caspases |
| Q42689739 | APP independent and dependent effects on neurite outgrowth are modulated by the receptor associated protein (RAP). |
| Q93033050 | Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues |
| Q48444707 | Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity. |
| Q26747569 | Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms |
| Q38767379 | Amyloid precursor like protein-1 promotes JNK-mediated cell migration in Drosophila |
| Q37427458 | Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors |
| Q35257809 | Amyloid precursor protein interaction network in human testis: sentinel proteins for male reproduction |
| Q34731871 | Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance |
| Q38933148 | Amyloid precursor protein processing and bioenergetics |
| Q36928448 | Amyloid precursor proteins interact with the heterotrimeric G protein Go in the control of neuronal migration |
| Q27012950 | Amyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's disease |
| Q34969012 | Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer |
| Q38883397 | Analysis of the amyloid precursor protein role in neuritogenesis reveals a biphasic SH-SY5Y neuronal cell differentiation model. |
| Q34241697 | Angiotensin converting enzyme (ACE) and ACE2 bind integrins and ACE2 regulates integrin signalling |
| Q38070883 | BACE1 influences debris clearance and axonal regeneration in injured peripheral nerve |
| Q48264035 | BRI2 Processing and Its Neuritogenic Role Are Modulated by Protein Phosphatase 1 Complexing. |
| Q47368687 | Beta secretase activity in peripheral nerve regeneration |
| Q34480173 | Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development |
| Q37869935 | Biology and pathophysiology of the amyloid precursor protein |
| Q58114173 | Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis |
| Q39432592 | Cerebrospinal Fluid Biomarkers in Alzheimer's Disease-From Brain Starch to Bench and Bedside |
| Q64882401 | Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications. |
| Q38781934 | Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease |
| Q90621944 | Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice |
| Q33622388 | Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression |
| Q34381637 | Comparative gene expression analysis in mouse models for multiple sclerosis, Alzheimer's disease and stroke for identifying commonly regulated and disease-specific gene changes |
| Q38045262 | Concise review: Can stem cells be used to treat or model Alzheimer's disease? |
| Q36937621 | Contributions of VLDLR and LRP8 in the establishment of retinogeniculate projections |
| Q34255981 | Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. |
| Q37405228 | Dosage of amyloid precursor protein affects axonal contact guidance in Down syndrome |
| Q28080897 | Dynamic self-guiding analysis of Alzheimer's disease |
| Q41907099 | Effects of cerebrovascular disease on amyloid precursor protein metabolites in cerebrospinal fluid |
| Q36525919 | Extracellular matrix molecules enhance the neurotrophic effect of Schwann cell-like differentiated adipose-derived stem cells and increase cell survival under stress conditions |
| Q38947884 | Extracellular matrix proteomics in schizophrenia and Alzheimer's disease. |
| Q35660090 | FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness |
| Q36925690 | Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue |
| Q34603848 | Follicular fluid Aβ40 concentrations may be associated with ongoing pregnancy following in vitro fertilization |
| Q37965817 | Functions of Aβ, sAPPα and sAPPβ : similarities and differences |
| Q37633601 | Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease |
| Q33665842 | Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism |
| Q64945281 | Identification of "sarsasapogenin-aglyconed" timosaponins as novel Aβ-lowering modulators of amyloid precursor protein processing. |
| Q35260723 | In utero electroporation followed by primary neuronal culture for studying gene function in subset of cortical neurons |
| Q28478681 | Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker |
| Q26999922 | Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease |
| Q24655186 | Interaction of reelin with amyloid precursor protein promotes neurite outgrowth |
| Q57899289 | Matrix metalloproteinase-9 and non-amyloidogenic pathway of amyloid precursor protein processing |
| Q33854483 | Multifaceted Roles of Metzincins in CNS Physiology and Pathology: From Synaptic Plasticity and Cognition to Neurodegenerative Disorders |
| Q34467566 | Neurogenin 2 mediates amyloid-β precursor protein-stimulated neurogenesis |
| Q39035050 | Neuronal migration during development and the amyloid precursor protein |
| Q48355470 | Neuroprotective effect of hesperidin on aluminium chloride induced Alzheimer's disease in Wistar rats. |
| Q30487766 | Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers |
| Q36293007 | New tricks from an old dog: Another synaptotoxic fragment from APP |
| Q39209681 | Not just amyloid: physiological functions of the amyloid precursor protein family |
| Q36595737 | Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain. |
| Q28593653 | Pancortins interact with amyloid precursor protein and modulate cortical cell migration |
| Q35568957 | Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing |
| Q39008879 | Peptide Pharmacological Approaches to Treating Traumatic Brain Injury: a Case for Arginine-Rich Peptides |
| Q37891181 | Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease |
| Q37987144 | Physiological functions of APP family proteins |
| Q27001550 | Platelets and Alzheimer's disease: Potential of APP as a biomarker |
| Q35827478 | Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system |
| Q38002193 | Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems |
| Q38929253 | Restoring Soluble Amyloid Precursor Protein α Functions as a Potential Treatment for Alzheimer's Disease. |
| Q39135552 | Role of APP Interactions with Heterotrimeric G Proteins: Physiological Functions and Pathological Consequences |
| Q28072008 | Role of Drosophila Amyloid Precursor Protein in Memory Formation |
| Q37956562 | Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging |
| Q33813121 | Secreted amyloid precursor protein β and secreted amyloid precursor protein α induce axon outgrowth in vitro through Egr1 signaling pathway |
| Q39432106 | Secreted amyloid precursor proteins promote proliferation and glial differentiation of adult hippocampal neural progenitor cells |
| Q33988005 | Secreted human amyloid precursor protein binds semaphorin 3a and prevents semaphorin-induced growth cone collapse. |
| Q36534395 | Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes. |
| Q47688609 | Soluble Amyloid Precursor Protein Alpha Interacts with alpha3-Na, K-ATPAse to Induce Axonal Outgrowth but Not Neuroprotection: Evidence for Distinct Mechanisms Underlying these Properties |
| Q26269904 | Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP |
| Q46573885 | Soluble amyloid precursor protein α in the cerebrospinal fluid as a diagnostic and prognostic biomarker for idiopathic normal pressure hydrocephalus |
| Q36462366 | Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation |
| Q46637160 | Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein. |
| Q27687528 | Structural aspects and physiological consequences of APP/APLP trans-dimerization |
| Q24600927 | Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein |
| Q37258141 | Systematic evaluation of candidate ligands regulating ectodomain shedding of amyloid precursor protein |
| Q41170054 | The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance. |
| Q88964540 | The Impact of APP on Alzheimer-like Pathogenesis and Gene Expression in Down Syndrome iPSC-Derived Neurons |
| Q26750116 | The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain Injury |
| Q47213827 | The amyloid precursor protein derivative, APP96-110, is efficacious following intravenous administration after traumatic brain injury |
| Q39118352 | The amyloid precursor protein represses expression of acetylcholinesterase in neuronal cell lines |
| Q36113757 | The keystone of Alzheimer pathogenesis might be sought in Aβ physiology |
| Q43478510 | The neuroprotective activity of the amyloid precursor protein against traumatic brain injury is mediated via the heparin binding site in residues 96-110. |
| Q93077432 | The new genetic landscape of Alzheimer's disease: from amyloid cascade to genetically driven synaptic failure hypothesis? |
| Q39414505 | The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system |
| Q40534733 | The precision of axon targeting of mouse olfactory sensory neurons requires the BACE1 protease |
| Q37825632 | The upside of APP at synapses |
| Q39145999 | Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα. |
| Q50052369 | Trans-Synaptic Spread of Amyloid-β in Alzheimer's Disease: Paths to β-Amyloidosis. |
| Q36278646 | Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult |
| Q38660086 | Vascular mTOR-dependent mechanisms linking the control of aging to Alzheimer's disease. |
| Q48558580 | sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury |
| Q47074139 | β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner |
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